Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes

EMBO Journal

Volumn 23, Issue 10, 2004, Pages 2134-2145

  Hill, Michelle M ^a,b   Adrain, Colin ^a   Duriez, Patrick J ^a   Creagh, Emma M ^a   Martin, Seamus J ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Apoptosis; Apoptosome; Caspase 9; PHAPI; XIAP

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN; PROTEIN PHAPI; PROTEINASE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRESS; STRUCTURE ANALYSIS;

ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; CARRIER PROTEINS; CASPASE 3; CASPASE 9; CASPASES; CYTOCHROMES C; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; MITOCHONDRIAL PROTEINS; MULTIPROTEIN COMPLEXES; PEPTIDE MAPPING; PROTEINS; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 2942532135     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600210     Document Type: Article

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