Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor κB: Differential regulation of collagenase 1 and collagenase 3

Arthritis and Rheumatism

Volumn 43, Issue 4, 2000, Pages 801-811

  Mengshol, John A ^a   Vincenti, Matthew P ^a   Coon, Charles I ^a   Barchowsky, Aaron ^a   Brinckerhoff, Constance E ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; REPRESSOR PROTEIN; STRESS ACTIVATED PROTEIN KINASE; STROMELYSIN; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CHONDROSARCOMA; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENE INDUCTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION;

CHONDROCYTES; COLLAGENASES; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; TRANSFECTION;

EID: 0033851463     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200004)43:4<801::AID-ANR10>3.0.CO;2-4     Document Type: Article

References (68)

1. Biology of the normal joint
2. Pathogenesis of osteoarthritis
3. Pathophysiology of osteoarthritis
4. Purification and cloning of aggrecanase-l: A member of the ADAMTS family of proteins
5. Osteoarthritic lesions: Involvement of three different collagenases
6. Matrix metalloproteinases
7. Proteolytic remodeling of extracellular matrix
8. Regulating expression of the gene for matrix metalloproteinase-1 (collagenase): Mechanisms that control enzyme activity, transcription, and mRNA stability
9. Methods in molecular biology
10. Different collagenase gene products have different roles in degradation of type I collagen
11. The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction
12. Degradation of cartilage aggrecan by collagenase-3 (MMP-13)
13. Biochemical characterization of human collagenase-3
14. Collagenase-3 (MMP-13) is expressed during human fetal ossification and re-expressed in postnatal bone remodeling and in rheumatoid arthritis
15. Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development
16. Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation
17. Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis
18. Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage
19. Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage
20. The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes: A role in osteoarthritis
21. Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: Localization in the pannus-hard tissue junction and inhibition by alendronate
22. Comparative immunolocalization studies of collagenase 1 and collagenase 3 production in the rheumatoid lesion, and by human chondrocytes and synoviocytes in vitro
23. Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium
24. Human collagenase-3 is expressed in malignant squamous epithelium of the skin
25. Expression of collagenase-3 (matrix metalloproteinase-13) in squamous cell carcinomas of the head and neck
26. Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas
27. Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions
28. Collagenase-3 (MMP-13) expression in chondrosarcoma cells and its regulation by basic fibroblast growth factor
29. Collagenase-3 (matrix metalloproteinase-13) expression is induced in oral mucosal epithelium during chronic inflammation
30. Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds
31. Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques
32. Biologic basis for interleukin-1 in disease
33. Cytokine control of interstitial collagenase and collagenase-3 gene expression in human chondrocytes
34. In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy
35. In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: Prevention of osteoarthritis progression
36. Signal transduction and transcription factors in rheumatic disease
37. Tumour necrosis factor alpha and interleukin 1 signalling: Do MAPKK kinases connect it all?
38. Mitogen-activated protein kinases: Specific messages from ubiquitous messengers
39. Signal transduction by the c-Jun N-terminal kinase (JNK) - From inflammation to development
40. Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes
41. Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
42. Structural analysis and promoter characterization of the human collagenase-3 gene (MMP13)
43. Cloning, sequencing and characterization of the 5'-flanking region of the human collagenase-3 gene
44. Defining therapeutic targets by using adenovirus: Blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators
45. Nuclear factor κB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1β-stimulated synovial fibroblasts
46. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
47. Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants
48. Induction of collagenase mRNA in lapine articular chondrocytes by synovial factors and interleukin-1
49. Cloning of the gene for interstitial collagenase-3 (matrix metalloproteinase-13) from rabbit synovial fibroblasts: Differential expression with collagenase-1 (matrix metalloproteinase-1)
50. A cytoplasmic inhibitor of the JNK signal transduction pathway
51. The JIP group of mitogen-activated protein kinase scaffold proteins
52. Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination
53. Two activator protein-1 elements in the matrix metalloproteinase-1 promoter have different effects on transcription and bind Jun D, c-Fos, and Fra-2
54. Different mechanisms of regulation of the human stromelysin and collagenase genes: Analysis by a reverse-transcription-coupled-PCR assay
55. AP-1 function and regulation
56. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
57. A synthetic inhibitor of the mitogen-activated protein kinase cascade
58. Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals
59. UV irradiation induces the murine urokinase-type plasminogen activator gene via the c-Jun N-terminal kinase signaling pathway: Requirement of an AP1 enhancer element
60. Actions of IL-1 are selectively controlled by p38 mitogen-activated protein kinase: Regulation of prostaglandin H synthase-2, metalloproteinases, and IL-6 at different levels
61. Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase
62. Pharmacological profile of SB 203580, a selective inhibitor of cytokine suppressive binding protein/p38 kinase, in animal models of arthritis, bone resorption, endotoxin shock and immune function
63. Organization and regulation of mitogen-activated protein kinase signaling pathways
64. The AP-1 site and MMP gene regulation: What is all the fuss about?
65. Transcriptional control of matrix metalloproteinases and the tissue inhibitors of matrix metalloproteinases
66. Parathyroid hormone regulates the rat collagenase-3 promoter in osteoblastic cells through the cooperative interaction of the activator protein-1 site and the runt domain binding sequence
67. Differential effects of transforming growth factor-beta on the expression of collagenase-1 and collagenase-3 in human fibroblasts
68. Mitogen-activated protein kinase pathways