Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein

Osteoarthritis and Cartilage

Volumn 22, Issue 7, 2014, Pages 1007-1017

  Uehara, Y ^a   Hirose, J ^b   Yamabe, S ^a   Okamoto, N ^a   Okada, T ^a   Oyadomari, S ^c   Mizuta, H ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

C EBP homologous protein; Cartilage degeneration; Chondrocyte apoptosis; Endoplasmic reticulum stress

Indexed keywords

AGGRECAN; CASPASE 3; COLLAGEN TYPE 2; COLLAGENASE 3; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; TUNICAMYCIN; X BOX BINDING PROTEIN 1; DDIT3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMUR; GENE EXPRESSION; GENE INACTIVATION; IMMUNOHISTOCHEMISTRY; LIGAMENT SURGERY; LIGAMENT TRANSECTION; MANKIN SCORE; MENISCECTOMY; MOUSE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL CULTURE; CHONDROPATHY; DEFICIENCY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECTS; GENETICS; HOMEOSTASIS; IN VITRO STUDY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGGRECANS; ANIMALS; APOPTOSIS; CARTILAGE DISEASES; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; IN VITRO TECHNIQUES; MATRIX METALLOPROTEINASE 13; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TRANSCRIPTION FACTOR CHOP; TUNICAMYCIN;

EID: 84903773914     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2014.04.025     Document Type: Article

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