-
1
-
-
33749681309
-
Sex ratio of multiple sclerosis in Canada: A longitudinal study
-
Canadian Collaborative Study Group
-
Orton S. M., Herrera B. M., Yee I. M., et al. Canadian Collaborative Study Group. Sex ratio of multiple sclerosis in Canada: a longitudinal study. Lancet Neurol: 2006; 5 11 932 936
-
(2006)
Lancet Neurol
, vol.5
, Issue.11
, pp. 932-936
-
-
Orton, S.M.1
Herrera, B.M.2
Yee, I.M.3
-
2
-
-
54149084585
-
Multiple sclerosis
-
Compston A., Coles A. Multiple sclerosis. Lancet: 2008; 372 9648 1502 1517
-
(2008)
Lancet
, vol.372
, Issue.9648
, pp. 1502-1517
-
-
Compston, A.1
Coles, A.2
-
3
-
-
80051684615
-
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
-
International Multiple Sclerosis Genetics Consortium; Wellcome Trust Case Control Consortium 2
-
Sawcer S., Hellenthal G., Pirinen M., et al. International Multiple Sclerosis Genetics Consortium; Wellcome Trust Case Control Consortium 2. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature: 2011; 476 7359 214 219
-
(2011)
Nature
, vol.476
, Issue.7359
, pp. 214-219
-
-
Sawcer, S.1
Hellenthal, G.2
Pirinen, M.3
-
4
-
-
84887058596
-
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
-
International Multiple Sclerosis Genetics Consortium (IMSGC); Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC
-
Beecham A. H., Patsopoulos N. A., Xifara D. K., et al. International Multiple Sclerosis Genetics Consortium (IMSGC); Wellcome Trust Case Control Consortium 2 (WTCCC2); International IBD Genetics Consortium (IIBDGC). Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet: 2013; 45 11 1353 1360
-
(2013)
Nat Genet
, vol.45
, Issue.11
, pp. 1353-1360
-
-
Beecham, A.H.1
Patsopoulos, N.A.2
Xifara, D.K.3
-
5
-
-
84868535570
-
The initiation and prevention of multiple sclerosis
-
Ascherio A., Munger K. L., Lünemann J. D. The initiation and prevention of multiple sclerosis. Nat Rev Neurol: 2012; 8 11 602 612
-
(2012)
Nat Rev Neurol
, vol.8
, Issue.11
, pp. 602-612
-
-
Ascherio, A.1
Munger, K.L.2
Lünemann, J.D.3
-
6
-
-
0032882173
-
Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis
-
Coles A. J., Wing M. G., Molyneux P., et al. Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis. Ann Neurol: 1999; 46 3 296 304
-
(1999)
Ann Neurol
, vol.46
, Issue.3
, pp. 296-304
-
-
Coles, A.J.1
Wing, M.G.2
Molyneux, P.3
-
7
-
-
0033759398
-
The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis. European Study Group on Interferon beta-1b in secondary progressive multiple sclerosis
-
Molyneux P. D., Kappos L., Polman C., et al. The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis. European Study Group on Interferon beta-1b in secondary progressive multiple sclerosis. Brain: 2000; 123 (Pt 11): 2256 2263
-
(2000)
Brain
, vol.123
, Issue.PART 11
, pp. 2256-2263
-
-
Molyneux, P.D.1
Kappos, L.2
Polman, C.3
-
8
-
-
0034194016
-
The effect of cladribine on T(1) 'black hole' changes in progressive MS
-
Filippi M., Rovaris M., Rice G. P., et al. The effect of cladribine on T(1) 'black hole' changes in progressive MS. J Neurol Sci: 2000; 176 1 42 44
-
(2000)
J Neurol Sci
, vol.176
, Issue.1
, pp. 42-44
-
-
Filippi, M.1
Rovaris, M.2
Rice, G.P.3
-
9
-
-
84922554905
-
Treatment of progressive multiple sclerosis: What works, what does not, and what is needed
-
Feinstein A., Freeman J., Lo A. C. Treatment of progressive multiple sclerosis: what works, what does not, and what is needed. Lancet Neurol: 2015; 14 2 194 207
-
(2015)
Lancet Neurol
, vol.14
, Issue.2
, pp. 194-207
-
-
Feinstein, A.1
Freeman, J.2
Lo, A.C.3
-
10
-
-
26444569231
-
MRI as a marker for disease heterogeneity in multiple sclerosis
-
Bielekova B., Kadom N., Fisher E., et al. MRI as a marker for disease heterogeneity in multiple sclerosis. Neurology: 2005; 65 7 1071 1076
-
(2005)
Neurology
, vol.65
, Issue.7
, pp. 1071-1076
-
-
Bielekova, B.1
Kadom, N.2
Fisher, E.3
-
11
-
-
27444448187
-
MRI evidence for multiple sclerosis as a diffuse disease of the central nervous system
-
Filippi M., Rocca M. A. MRI evidence for multiple sclerosis as a diffuse disease of the central nervous system. J Neurol: 2005; 252 05 v16 v24
-
(2005)
J Neurol
, vol.252
, pp. v16-v24
-
-
Filippi, M.1
Rocca, M.A.2
-
12
-
-
33646201174
-
Magnetic resonance imaging measures of brain atrophy in multiple sclerosis
-
Anderson V. M., Fox N. C., Miller D. H. Magnetic resonance imaging measures of brain atrophy in multiple sclerosis. J Magn Reson Imaging: 2006; 23 5 605 618
-
(2006)
J Magn Reson Imaging
, vol.23
, Issue.5
, pp. 605-618
-
-
Anderson, V.M.1
Fox, N.C.2
Miller, D.H.3
-
13
-
-
34248643430
-
Neuroimaging in multiple sclerosis
-
Zivadinov R., Cox J. L. Neuroimaging in multiple sclerosis. Int Rev Neurobiol: 2007; 79 449 474
-
(2007)
Int Rev Neurobiol
, vol.79
, pp. 449-474
-
-
Zivadinov, R.1
Cox, J.L.2
-
14
-
-
66549130329
-
The relation between inflammation and neurodegeneration in multiple sclerosis brains
-
Frischer J. M., Bramow S., Dal-Bianco A., et al. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain: 2009; 132 (Pt 5): 1175 1189
-
(2009)
Brain
, vol.132
, Issue.PART 5
, pp. 1175-1189
-
-
Frischer, J.M.1
Bramow, S.2
Dal-Bianco, A.3
-
15
-
-
0035833965
-
Axonal loss in normal-appearing white matter in a patient with acute MS
-
Bjartmar C., Kinkel R. P., Kidd G., Rudick R. A., Trapp B. D. Axonal loss in normal-appearing white matter in a patient with acute MS. Neurology: 2001; 57 7 1248 1252
-
(2001)
Neurology
, vol.57
, Issue.7
, pp. 1248-1252
-
-
Bjartmar, C.1
Kinkel, R.P.2
Kidd, G.3
Rudick, R.A.4
Trapp, B.D.5
-
16
-
-
33745115644
-
The contribution of demyelination to axonal loss in multiple sclerosis
-
DeLuca G. C., Williams K., Evangelou N., Ebers G. C., Esiri M. M. The contribution of demyelination to axonal loss in multiple sclerosis. Brain: 2006; 129 (Pt 6): 1507 1516
-
(2006)
Brain
, vol.129
, Issue.PART 6
, pp. 1507-1516
-
-
DeLuca, G.C.1
Williams, K.2
Evangelou, N.3
Ebers, G.C.4
Esiri, M.M.5
-
17
-
-
0033870097
-
Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions
-
Kornek B., Storch M. K., Weissert R., et al. Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions. Am J Pathol: 2000; 157 1 267 276
-
(2000)
Am J Pathol
, vol.157
, Issue.1
, pp. 267-276
-
-
Kornek, B.1
Storch, M.K.2
Weissert, R.3
-
18
-
-
0034842126
-
Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
-
Peterson J. W., Bö L., Mörk S., Chang A., Trapp B. D. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol: 2001; 50 3 389 400
-
(2001)
Ann Neurol
, vol.50
, Issue.3
, pp. 389-400
-
-
Peterson, J.W.1
Bö, L.2
Mörk, S.3
Chang, A.4
Trapp, B.D.5
-
19
-
-
0042123685
-
Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration
-
Bo L., Vedeler C. A., Nyland H., Trapp B. D., Mork S. J. Intracortical multiple sclerosis lesions are not associated with increased lymphocyte infiltration. Mult Scler: 2003; 9 4 323 331
-
(2003)
Mult Scler
, vol.9
, Issue.4
, pp. 323-331
-
-
Bo, L.1
Vedeler, C.A.2
Nyland, H.3
Trapp, B.D.4
Mork, S.J.5
-
20
-
-
0032576752
-
Axonal transection in the lesions of multiple sclerosis
-
Trapp B. D., Peterson J., Ransohoff R. M., Rudick R., Mörk S., Bö L. Axonal transection in the lesions of multiple sclerosis. N Engl J Med: 1998; 338 5 278 285
-
(1998)
N Engl J Med
, vol.338
, Issue.5
, pp. 278-285
-
-
Trapp, B.D.1
Peterson, J.2
Ransohoff, R.M.3
Rudick, R.4
Mörk, S.5
Bö, L.6
-
21
-
-
0036161001
-
Brain atrophy in clinically early relapsing-remitting multiple sclerosis
-
Chard D. T., Griffin C. M., Parker G. J., Kapoor R., Thompson A. J., Miller D. H. Brain atrophy in clinically early relapsing-remitting multiple sclerosis. Brain: 2002; 125 (Pt 2): 327 337
-
(2002)
Brain
, vol.125
, Issue.PART 2
, pp. 327-337
-
-
Chard, D.T.1
Griffin, C.M.2
Parker, G.J.3
Kapoor, R.4
Thompson, A.J.5
Miller, D.H.6
-
22
-
-
0036342788
-
Measurement of atrophy in multiple sclerosis: Pathological basis, methodological aspects and clinical relevance
-
Miller D. H., Barkhof F., Frank J. A., Parker G. J., Thompson A. J. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain: 2002; 125 (Pt 8): 1676 1695
-
(2002)
Brain
, vol.125
, Issue.PART 8
, pp. 1676-1695
-
-
Miller, D.H.1
Barkhof, F.2
Frank, J.A.3
Parker, G.J.4
Thompson, A.J.5
-
23
-
-
84876331426
-
Loss of retinal nerve fibre layer axons indicates white but not grey matter damage in early multiple sclerosis
-
Young K. L., Brandt A. U., Petzold A., et al. Loss of retinal nerve fibre layer axons indicates white but not grey matter damage in early multiple sclerosis. Eur J Neurol: 2013; 20 5 803 811
-
(2013)
Eur J Neurol
, vol.20
, Issue.5
, pp. 803-811
-
-
Young, K.L.1
Brandt, A.U.2
Petzold, A.3
-
24
-
-
79954568567
-
Neurofilament heavy chain in CSF correlates with relapses and disability in multiple sclerosis
-
Kuhle J., Leppert D., Petzold A., et al. Neurofilament heavy chain in CSF correlates with relapses and disability in multiple sclerosis. Neurology: 2011; 76 14 1206 1213
-
(2011)
Neurology
, vol.76
, Issue.14
, pp. 1206-1213
-
-
Kuhle, J.1
Leppert, D.2
Petzold, A.3
-
25
-
-
0342906187
-
Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
-
Lucchinetti C., Brück W., Parisi J., Scheithauer B., Rodriguez M., Lassmann H. Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination. Ann Neurol: 2000; 47 6 707 717
-
(2000)
Ann Neurol
, vol.47
, Issue.6
, pp. 707-717
-
-
Lucchinetti, C.1
Brück, W.2
Parisi, J.3
Scheithauer, B.4
Rodriguez, M.5
Lassmann, H.6
-
26
-
-
84902199860
-
Pathologic heterogeneity persists in early active multiple sclerosis lesions
-
Metz I., Weigand S. D., Popescu B. F., et al. Pathologic heterogeneity persists in early active multiple sclerosis lesions. Ann Neurol: 2014; 75 5 728 738
-
(2014)
Ann Neurol
, vol.75
, Issue.5
, pp. 728-738
-
-
Metz, I.1
Weigand, S.D.2
Popescu, B.F.3
-
27
-
-
1642281535
-
Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion
-
Barnett M. H., Prineas J. W. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol: 2004; 55 4 458 468
-
(2004)
Ann Neurol
, vol.55
, Issue.4
, pp. 458-468
-
-
Barnett, M.H.1
Prineas, J.W.2
-
28
-
-
39049163500
-
Homogeneity of active demyelinating lesions in established multiple sclerosis
-
Breij E. C., Brink B. P., Veerhuis R., et al. Homogeneity of active demyelinating lesions in established multiple sclerosis. Ann Neurol: 2008; 63 1 16 25
-
(2008)
Ann Neurol
, vol.63
, Issue.1
, pp. 16-25
-
-
Breij, E.C.1
Brink, B.P.2
Veerhuis, R.3
-
29
-
-
1542327620
-
Expression of chemokine receptors CCR1 and CCR5 reflects differential activation of mononuclear phagocytes in pattern II and pattern III multiple sclerosis lesions
-
Mahad D. J., Trebst C., Kivisäkk P., et al. Expression of chemokine receptors CCR1 and CCR5 reflects differential activation of mononuclear phagocytes in pattern II and pattern III multiple sclerosis lesions. J Neuropathol Exp Neurol: 2004; 63 3 262 273
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, Issue.3
, pp. 262-273
-
-
Mahad, D.J.1
Trebst, C.2
Kivisäkk, P.3
-
30
-
-
23744454283
-
Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange
-
Keegan M., König F., McClelland R., et al. Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange. Lancet: 2005; 366 9485 579 582
-
(2005)
Lancet
, vol.366
, Issue.9485
, pp. 579-582
-
-
Keegan, M.1
König, F.2
McClelland, R.3
-
31
-
-
57749094962
-
Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis
-
Quintana F. J., Farez M. F., Viglietta V., et al. Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis. Proc Natl Acad Sci U S A: 2008; 105 48 18889 18894
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.48
, pp. 18889-18894
-
-
Quintana, F.J.1
Farez, M.F.2
Viglietta, V.3
-
32
-
-
84955362019
-
Central role of Th2/Tc2 lymphocytes in pattern II multiple sclerosis lesions
-
Planas R., Metz I., Ortiz Y., et al. Central role of Th2/Tc2 lymphocytes in pattern II multiple sclerosis lesions. Ann Clin Transl Neurol: 2015; 2 9 875 893
-
(2015)
Ann Clin Transl Neurol
, vol.2
, Issue.9
, pp. 875-893
-
-
Planas, R.1
Metz, I.2
Ortiz, Y.3
-
33
-
-
0021328623
-
Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice
-
Mokhtarian F., McFarlin D. E., Raine C. S. Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice. Nature: 1984; 309 5966 356 358
-
(1984)
Nature
, vol.309
, Issue.5966
, pp. 356-358
-
-
Mokhtarian, F.1
McFarlin, D.E.2
Raine, C.S.3
-
34
-
-
0022974996
-
T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis
-
Zamvil S. S., Mitchell D. J., Moore A. C., Kitamura K., Steinman L., Rothbard J. B. T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature: 1986; 324 6094 258 260
-
(1986)
Nature
, vol.324
, Issue.6094
, pp. 258-260
-
-
Zamvil, S.S.1
Mitchell, D.J.2
Moore, A.C.3
Kitamura, K.4
Steinman, L.5
Rothbard, J.B.6
-
35
-
-
0024213789
-
Susceptibility to PLP-induced EAE is regulated by non-H-2 genes
-
Tuohy V. K., Sobel R. A., Lees M. B. Susceptibility to PLP-induced EAE is regulated by non-H-2 genes. Ann N Y Acad Sci: 1988; 540 709 711
-
(1988)
Ann N y Acad Sci
, vol.540
, pp. 709-711
-
-
Tuohy, V.K.1
Sobel, R.A.2
Lees, M.B.3
-
36
-
-
0029038922
-
A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: Fine specificity and T cell receptor v beta expression of encephalitogenic T cells
-
Mendel I., Kerlero de Rosbo N., Ben-Nun A. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cells. Eur J Immunol: 1995; 25 7 1951 1959
-
(1995)
Eur J Immunol
, vol.25
, Issue.7
, pp. 1951-1959
-
-
Mendel, I.1
Kerlero De Rosbo, N.2
Ben-Nun, A.3
-
37
-
-
0027990803
-
Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia
-
Kojima K., Berger T., Lassmann H., et al. Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia. J Exp Med: 1994; 180 3 817 829
-
(1994)
J Exp Med
, vol.180
, Issue.3
, pp. 817-829
-
-
Kojima, K.1
Berger, T.2
Lassmann, H.3
-
39
-
-
0019465142
-
The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis
-
Ben-Nun A., Wekerle H., Cohen I. R. The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur J Immunol: 1981; 11 3 195 199
-
(1981)
Eur J Immunol
, vol.11
, Issue.3
, pp. 195-199
-
-
Ben-Nun, A.1
Wekerle, H.2
Cohen, I.R.3
-
40
-
-
0019465748
-
Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: Requirement for Lyt 1+ 2- T lymphocytes
-
Pettinelli C. B., McFarlin D. E. Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes. J Immunol: 1981; 127 4 1420 1423
-
(1981)
J Immunol
, vol.127
, Issue.4
, pp. 1420-1423
-
-
Pettinelli, C.B.1
McFarlin, D.E.2
-
41
-
-
0032719206
-
A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor
-
Madsen L. S., Andersson E. C., Jansson L., et al. A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nat Genet: 1999; 23 3 343 347
-
(1999)
Nat Genet
, vol.23
, Issue.3
, pp. 343-347
-
-
Madsen, L.S.1
Andersson, E.C.2
Jansson, L.3
-
42
-
-
84866147769
-
Myelin basic protein-specific TCR/HLA-DRB5∗01:01 transgenic mice support the etiologic role of DRB5∗01:01 in multiple sclerosis
-
Quandt J. A., Huh J., Baig M., et al. Myelin basic protein-specific TCR/HLA-DRB5∗01:01 transgenic mice support the etiologic role of DRB5∗01:01 in multiple sclerosis. J Immunol: 2012; 189 6 2897 2908
-
(2012)
J Immunol
, vol.189
, Issue.6
, pp. 2897-2908
-
-
Quandt, J.A.1
Huh, J.2
Baig, M.3
-
43
-
-
3242800448
-
Unique clinical and pathological features in HLA-DRB1∗0401-restricted MBP 111-129-specific humanized TCR transgenic mice
-
Quandt J. A., Baig M., Yao K., et al. Unique clinical and pathological features in HLA-DRB1∗0401-restricted MBP 111-129-specific humanized TCR transgenic mice. J Exp Med: 2004; 200 2 223 234
-
(2004)
J Exp Med
, vol.200
, Issue.2
, pp. 223-234
-
-
Quandt, J.A.1
Baig, M.2
Yao, K.3
-
44
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
International Multiple Sclerosis Genetics Consortium
-
Hafler D. A., Compston A., Sawcer S., et al. International Multiple Sclerosis Genetics Consortium. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med: 2007; 357 9 851 862
-
(2007)
N Engl J Med
, vol.357
, Issue.9
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
-
45
-
-
81855167104
-
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
-
Berer K., Mues M., Koutrolos M., et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature: 2011; 479 7374 538 541
-
(2011)
Nature
, vol.479
, Issue.7374
, pp. 538-541
-
-
Berer, K.1
Mues, M.2
Koutrolos, M.3
-
46
-
-
84865469861
-
T cells become licensed in the lung to enter the central nervous system
-
Odoardi F., Sie C., Streyl K., et al. T cells become licensed in the lung to enter the central nervous system. Nature: 2012; 488 7413 675 679
-
(2012)
Nature
, vol.488
, Issue.7413
, pp. 675-679
-
-
Odoardi, F.1
Sie, C.2
Streyl, K.3
-
47
-
-
84889098870
-
Remote control-triggering of brain autoimmune disease in the gut
-
Wekerle H., Berer K., Krishnamoorthy G. Remote control-triggering of brain autoimmune disease in the gut. Curr Opin Immunol: 2013; 25 6 683 689
-
(2013)
Curr Opin Immunol
, vol.25
, Issue.6
, pp. 683-689
-
-
Wekerle, H.1
Berer, K.2
Krishnamoorthy, G.3
-
48
-
-
70349305736
-
Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis
-
Hedström A. K., Bäärnhielm M., Olsson T., Alfredsson L. Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis. Neurology: 2009; 73 9 696 701
-
(2009)
Neurology
, vol.73
, Issue.9
, pp. 696-701
-
-
Hedström, A.K.1
Bäärnhielm, M.2
Olsson, T.3
Alfredsson, L.4
-
49
-
-
84876787121
-
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
-
Kleinewietfeld M., Manzel A., Titze J., et al. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature: 2013; 496 7446 518 522
-
(2013)
Nature
, vol.496
, Issue.7446
, pp. 518-522
-
-
Kleinewietfeld, M.1
Manzel, A.2
Titze, J.3
-
50
-
-
84866364390
-
The anatomical and cellular basis of immune surveillance in the central nervous system
-
Ransohoff R. M., Engelhardt B. The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol: 2012; 12 9 623 635
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.9
, pp. 623-635
-
-
Ransohoff, R.M.1
Engelhardt, B.2
-
51
-
-
0022375427
-
Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity
-
Fujinami R. S., Oldstone M. B. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity. Science: 1985; 230 4729 1043 1045
-
(1985)
Science
, vol.230
, Issue.4729
, pp. 1043-1045
-
-
Fujinami, R.S.1
Oldstone, M.B.2
-
52
-
-
0032915806
-
Molecular mimicry and multiple sclerosis: Degenerate T-cell recognition and the induction of autoimmunity
-
Gran B., Hemmer B., Vergelli M., McFarland H. F., Martin R. Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity. Ann Neurol: 1999; 45 5 559 567
-
(1999)
Ann Neurol
, vol.45
, Issue.5
, pp. 559-567
-
-
Gran, B.1
Hemmer, B.2
Vergelli, M.3
McFarland, H.F.4
Martin, R.5
-
53
-
-
0028926223
-
Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
-
Wucherpfennig K. W., Strominger J. L. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell: 1995; 80 5 695 705
-
(1995)
Cell
, vol.80
, Issue.5
, pp. 695-705
-
-
Wucherpfennig, K.W.1
Strominger, J.L.2
-
54
-
-
0030925578
-
Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone
-
Hemmer B., Fleckenstein B. T., Vergelli M., et al. Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone. J Exp Med: 1997; 185 9 1651 1659
-
(1997)
J Exp Med
, vol.185
, Issue.9
, pp. 1651-1659
-
-
Hemmer, B.1
Fleckenstein, B.T.2
Vergelli, M.3
-
55
-
-
0032728738
-
Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease
-
Hemmer B., Gran B., Zhao Y., et al. Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease. Nat Med: 1999; 5 12 1375 1382
-
(1999)
Nat Med
, vol.5
, Issue.12
, pp. 1375-1382
-
-
Hemmer, B.1
Gran, B.2
Zhao, Y.3
-
56
-
-
0036793245
-
A functional and structural basis for TCR cross-reactivity in multiple sclerosis
-
Lang H. L., Jacobsen H., Ikemizu S., et al. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol: 2002; 3 10 940 943
-
(2002)
Nat Immunol
, vol.3
, Issue.10
, pp. 940-943
-
-
Lang, H.L.1
Jacobsen, H.2
Ikemizu, S.3
-
57
-
-
31144473847
-
Redundancy in antigen-presenting function of the HLA-DR and -DQ molecules in the multiple sclerosis-associated HLA-DR2 haplotype
-
Sospedra M., Muraro P. A., Stefanová I., et al. Redundancy in antigen-presenting function of the HLA-DR and -DQ molecules in the multiple sclerosis-associated HLA-DR2 haplotype. J Immunol: 2006; 176 3 1951 1961
-
(2006)
J Immunol
, vol.176
, Issue.3
, pp. 1951-1961
-
-
Sospedra, M.1
Muraro, P.A.2
Stefanová, I.3
-
58
-
-
84866564112
-
TCR bias and HLA cross-restriction are strategies of human brain-infiltrating JC virus-specific CD4+ T cells during viral infection
-
Yousef S., Planas R., Chakroun K., et al. TCR bias and HLA cross-restriction are strategies of human brain-infiltrating JC virus-specific CD4+ T cells during viral infection. J Immunol: 2012; 189 7 3618 3630
-
(2012)
J Immunol
, vol.189
, Issue.7
, pp. 3618-3630
-
-
Yousef, S.1
Planas, R.2
Chakroun, K.3
-
59
-
-
0021856495
-
Clinical viral infections and multiple sclerosis
-
Sibley W. A., Bamford C. R., Clark K. Clinical viral infections and multiple sclerosis. Lancet: 1985; 1 8441 1313 1315
-
(1985)
Lancet
, vol.1
, Issue.8441
, pp. 1313-1315
-
-
Sibley, W.A.1
Bamford, C.R.2
Clark, K.3
-
60
-
-
17644396349
-
Immunology of multiple sclerosis
-
Sospedra M., Martin R. Immunology of multiple sclerosis. Annu Rev Immunol: 2005; 23 683 747
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
61
-
-
84929630106
-
Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis
-
Cao Y., Goods B. A., Raddassi K., et al. Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis. Sci Transl Med: 2015; 7 287 287ra74
-
(2015)
Sci Transl Med
, vol.7
, Issue.287
, pp. 287ra74
-
-
Cao, Y.1
Goods, B.A.2
Raddassi, K.3
-
62
-
-
0034773579
-
CD4+CD28- costimulation-independent T cells in multiple sclerosis
-
Markovic-Plese S., Cortese I., Wandinger K. P., McFarland H. F., Martin R. CD4+CD28- costimulation-independent T cells in multiple sclerosis. J Clin Invest: 2001; 108 8 1185 1194
-
(2001)
J Clin Invest
, vol.108
, Issue.8
, pp. 1185-1194
-
-
Markovic-Plese, S.1
Cortese, I.2
Wandinger, K.P.3
McFarland, H.F.4
Martin, R.5
-
63
-
-
1342345214
-
The CD4-Th1 model for multiple sclerosis: A critical [correction of crucial] re-appraisal
-
Lassmann H., Ransohoff R. M. The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisal. Trends Immunol: 2004; 25 3 132 137
-
(2004)
Trends Immunol
, vol.25
, Issue.3
, pp. 132-137
-
-
Lassmann, H.1
Ransohoff, R.M.2
-
64
-
-
0030890461
-
HPRT mutant T-cell lines from multiple sclerosis patients recognize myelin proteolipid protein peptides
-
Trotter J. L., Damico C. A., Cross A. H., et al. HPRT mutant T-cell lines from multiple sclerosis patients recognize myelin proteolipid protein peptides. J Neuroimmunol: 1997; 75 1-2 95 103
-
(1997)
J Neuroimmunol
, vol.75
, Issue.12
, pp. 95-103
-
-
Trotter, J.L.1
Damico, C.A.2
Cross, A.H.3
-
65
-
-
1542723658
-
Expansion and functional relevance of high-avidity myelin-specific CD4+ T cells in multiple sclerosis
-
Bielekova B., Sung M. H., Kadom N., Simon R., McFarland H., Martin R. Expansion and functional relevance of high-avidity myelin-specific CD4+ T cells in multiple sclerosis. J Immunol: 2004; 172 6 3893 3904
-
(2004)
J Immunol
, vol.172
, Issue.6
, pp. 3893-3904
-
-
Bielekova, B.1
Sung, M.H.2
Kadom, N.3
Simon, R.4
McFarland, H.5
Martin, R.6
-
66
-
-
0033786776
-
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
-
Bielekova B., Goodwin B., Richert N., et al. Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand. Nat Med: 2000; 6 10 1167 1175
-
(2000)
Nat Med
, vol.6
, Issue.10
, pp. 1167-1175
-
-
Bielekova, B.1
Goodwin, B.2
Richert, N.3
-
67
-
-
0037228871
-
Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders
-
Muraro P. A., Wandinger K. P., Bielekova B., et al. Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. Brain: 2003; 126 Pt 1 20 31
-
(2003)
Brain
, vol.126
, Issue.PART 1
, pp. 20-31
-
-
Muraro, P.A.1
Wandinger, K.P.2
Bielekova, B.3
-
68
-
-
77956340532
-
Two HLA class i genes independently associated with multiple sclerosis
-
Link J., Lorentzen A. R., Kockum I., et al. Two HLA class I genes independently associated with multiple sclerosis. J Neuroimmunol: 2010; 226 1-2 172 176
-
(2010)
J Neuroimmunol
, vol.226
, Issue.12
, pp. 172-176
-
-
Link, J.1
Lorentzen, A.R.2
Kockum, I.3
-
69
-
-
77955854940
-
HLA B∗44: Protective effects in MS susceptibility and MRI outcome measures
-
Healy B. C., Liguori M., Tran D., et al. HLA B∗44: protective effects in MS susceptibility and MRI outcome measures. Neurology: 2010; 75 7 634 640
-
(2010)
Neurology
, vol.75
, Issue.7
, pp. 634-640
-
-
Healy, B.C.1
Liguori, M.2
Tran, D.3
-
70
-
-
55549104692
-
Opposing effects of HLA class i molecules in tuning autoreactive CD8+ T cells in multiple sclerosis
-
Friese M. A., Jakobsen K. B., Friis L., et al. Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis. Nat Med: 2008; 14 11 1227 1235
-
(2008)
Nat Med
, vol.14
, Issue.11
, pp. 1227-1235
-
-
Friese, M.A.1
Jakobsen, K.B.2
Friis, L.3
-
71
-
-
45749157611
-
Priming of CD8+ T cells during central nervous system infection with a murine coronavirus is strain dependent
-
MacNamara K. C., Bender S. J., Chua M. M., Watson R., Weiss S. R. Priming of CD8+ T cells during central nervous system infection with a murine coronavirus is strain dependent. J Virol: 2008; 82 13 6150 6160
-
(2008)
J Virol
, vol.82
, Issue.13
, pp. 6150-6160
-
-
MacNamara, K.C.1
Bender, S.J.2
Chua, M.M.3
Watson, R.4
Weiss, S.R.5
-
72
-
-
0022459287
-
Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions
-
Hauser S. L., Bhan A. K., Gilles F., Kemp M., Kerr C., Weiner H. L. Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions. Ann Neurol: 1986; 19 6 578 587
-
(1986)
Ann Neurol
, vol.19
, Issue.6
, pp. 578-587
-
-
Hauser, S.L.1
Bhan, A.K.2
Gilles, F.3
Kemp, M.4
Kerr, C.5
Weiner, H.L.6
-
73
-
-
0034618094
-
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
-
Babbe H., Roers A., Waisman A., et al. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J Exp Med: 2000; 192 3 393 404
-
(2000)
J Exp Med
, vol.192
, Issue.3
, pp. 393-404
-
-
Babbe, H.1
Roers, A.2
Waisman, A.3
-
74
-
-
1442354894
-
Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood
-
Skulina C., Schmidt S., Dornmair K., et al. Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proc Natl Acad Sci U S A: 2004; 101 8 2428 2433
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.8
, pp. 2428-2433
-
-
Skulina, C.1
Schmidt, S.2
Dornmair, K.3
-
75
-
-
35648948324
-
Multiple sclerosis: T-cell receptor expression in distinct brain regions
-
Junker A., Ivanidze J., Malotka J., et al. Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain: 2007; 130 (Pt 11): 2789 2799
-
(2007)
Brain
, vol.130
, Issue.PART 11
, pp. 2789-2799
-
-
Junker, A.1
Ivanidze, J.2
Malotka, J.3
-
76
-
-
0029079852
-
Induction of MHC class i genes in neurons
-
Neumann H., Cavalié A., Jenne D. E., Wekerle H. Induction of MHC class I genes in neurons. Science: 1995; 269 5223 549 552
-
(1995)
Science
, vol.269
, Issue.5223
, pp. 549-552
-
-
Neumann, H.1
Cavalié, A.2
Jenne, D.E.3
Wekerle, H.4
-
77
-
-
84943186954
-
Neurons and T cells: Understanding this interaction for inflammatory neurological diseases
-
Yshii L., Gebauer C., Bernard-Valnet R., Liblau R. Neurons and T cells: Understanding this interaction for inflammatory neurological diseases. Eur J Immunol: 2015; 45 10 2712 2720
-
(2015)
Eur J Immunol
, vol.45
, Issue.10
, pp. 2712-2720
-
-
Yshii, L.1
Gebauer, C.2
Bernard-Valnet, R.3
Liblau, R.4
-
78
-
-
0029792284
-
IFN-secreting cells
-
Olsson T., Wallström E. IFN-secreting cells. Neurology: 1996; 47 3 854 855
-
(1996)
Neurology
, vol.47
, Issue.3
, pp. 854-855
-
-
Olsson, T.1
Wallström, E.2
-
79
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington L. E., Hatton R. D., Mangan P. R., et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol: 2005; 6 11 1123 1132
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
80
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H., Li Z., Yang X. O., et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol: 2005; 6 11 1133 1141
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
-
81
-
-
84866749073
-
Defining the human T helper 17 cell phenotype
-
Annunziato F., Cosmi L., Liotta F., Maggi E., Romagnani S. Defining the human T helper 17 cell phenotype. Trends Immunol: 2012; 33 10 505 512
-
(2012)
Trends Immunol
, vol.33
, Issue.10
, pp. 505-512
-
-
Annunziato, F.1
Cosmi, L.2
Liotta, F.3
Maggi, E.4
Romagnani, S.5
-
82
-
-
79956116032
-
RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
-
Codarri L., Gyülvészi G., Tosevski V., et al. RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nat Immunol: 2011; 12 6 560 567
-
(2011)
Nat Immunol
, vol.12
, Issue.6
, pp. 560-567
-
-
Codarri, L.1
Gyülvészi, G.2
Tosevski, V.3
-
84
-
-
46949086111
-
A rush to judgment on Th17
-
Steinman L. A rush to judgment on Th17. J Exp Med: 2008; 205 7 1517 1522
-
(2008)
J Exp Med
, vol.205
, Issue.7
, pp. 1517-1522
-
-
Steinman, L.1
-
85
-
-
34948909646
-
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
-
Kebir H., Kreymborg K., Ifergan I., et al. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat Med: 2007; 13 10 1173 1175
-
(2007)
Nat Med
, vol.13
, Issue.10
, pp. 1173-1175
-
-
Kebir, H.1
Kreymborg, K.2
Ifergan, I.3
-
86
-
-
38749143286
-
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos J. S., Friese M. A., Craner M. J., et al. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am J Pathol: 2008; 172 1 146 155
-
(2008)
Am J Pathol
, vol.172
, Issue.1
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.2
Craner, M.J.3
-
87
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
Lock C., Hermans G., Pedotti R., et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med: 2002; 8 5 500 508
-
(2002)
Nat Med
, vol.8
, Issue.5
, pp. 500-508
-
-
Lock, C.1
Hermans, G.2
Pedotti, R.3
-
88
-
-
84921753054
-
+ T cell clones primed by pathogens or vaccines
-
+ T cell clones primed by pathogens or vaccines. Science: 2015; 347 6220 400 406
-
(2015)
Science
, vol.347
, Issue.6220
, pp. 400-406
-
-
Becattini, S.1
Latorre, D.2
Mele, F.3
-
89
-
-
67649881102
-
Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
-
Australia and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene) Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nat Genet: 2009; 41 7 824 828
-
(2009)
Nat Genet
, vol.41
, Issue.7
, pp. 824-828
-
-
-
90
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
International MS Genetics Consortium
-
De Jager P. L., Jia X., Wang J., et al. International MS Genetics Consortium. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet: 2009; 41 7 776 782
-
(2009)
Nat Genet
, vol.41
, Issue.7
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
-
91
-
-
35748981184
-
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
-
Wellcome Trust Case Control Consortium; Australo-Anglo-American Spondylitis Consortium (TASC); Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee; Breast Cancer Susceptibility Collaboration (UK
-
Burton P. R., Clayton D. G., Cardon L. R., et al. Wellcome Trust Case Control Consortium; Australo-Anglo-American Spondylitis Consortium (TASC); Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee; Breast Cancer Susceptibility Collaboration (UK). Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet: 2007; 39 11 1329 1337
-
(2007)
Nat Genet
, vol.39
, Issue.11
, pp. 1329-1337
-
-
Burton, P.R.1
Clayton, D.G.2
Cardon, L.R.3
-
92
-
-
34548351247
-
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis
-
Multiple Sclerosis Genetics Group
-
Gregory S. G., Schmidt S., Seth P., et al. Multiple Sclerosis Genetics Group. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet: 2007; 39 9 1083 1091
-
(2007)
Nat Genet
, vol.39
, Issue.9
, pp. 1083-1091
-
-
Gregory, S.G.1
Schmidt, S.2
Seth, P.3
-
93
-
-
38549180589
-
Haplotypes of the interleukin 7 receptor alpha gene are correlated with altered expression in whole blood cells in multiple sclerosis
-
McKay F. C., Swain L. I., Schibeci S. D., et al. Haplotypes of the interleukin 7 receptor alpha gene are correlated with altered expression in whole blood cells in multiple sclerosis. Genes Immun: 2008; 9 1 1 6
-
(2008)
Genes Immun
, vol.9
, Issue.1
, pp. 1-6
-
-
McKay, F.C.1
Swain, L.I.2
Schibeci, S.D.3
-
94
-
-
84886720726
-
IL7RA haplotype-associated alterations in cellular immune function and gene expression patterns in multiple sclerosis
-
Jäger J., Schulze C., Rösner S., Martin R. IL7RA haplotype-associated alterations in cellular immune function and gene expression patterns in multiple sclerosis. Genes Immun: 2013; 14 7 453 461
-
(2013)
Genes Immun
, vol.14
, Issue.7
, pp. 453-461
-
-
Jäger, J.1
Schulze, C.2
Rösner, S.3
Martin, R.4
-
95
-
-
44449135110
-
Lack of TIM-3 immunoregulation in multiple sclerosis
-
Yang L., Anderson D. E., Kuchroo J., Hafler D. A. Lack of TIM-3 immunoregulation in multiple sclerosis. J Immunol: 2008; 180 7 4409 4414
-
(2008)
J Immunol
, vol.180
, Issue.7
, pp. 4409-4414
-
-
Yang, L.1
Anderson, D.E.2
Kuchroo, J.3
Hafler, D.A.4
-
96
-
-
33745035874
-
Dysregulated T cell expression of TIM3 in multiple sclerosis
-
Koguchi K., Anderson D. E., Yang L., O'Connor K. C., Kuchroo V. K., Hafler D. A. Dysregulated T cell expression of TIM3 in multiple sclerosis. J Exp Med: 2006; 203 6 1413 1418
-
(2006)
J Exp Med
, vol.203
, Issue.6
, pp. 1413-1418
-
-
Koguchi, K.1
Anderson, D.E.2
Yang, L.3
O'Connor, K.C.4
Kuchroo, V.K.5
Hafler, D.A.6
-
97
-
-
84908142768
-
A multiple sclerosis-associated variant of CBLB links genetic risk with type i IFN function
-
Stürner K. H., Borgmeyer U., Schulze C., Pless O., Martin R. A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function. J Immunol: 2014; 193 9 4439 4447
-
(2014)
J Immunol
, vol.193
, Issue.9
, pp. 4439-4447
-
-
Stürner, K.H.1
Borgmeyer, U.2
Schulze, C.3
Pless, O.4
Martin, R.5
-
98
-
-
84929093567
-
New candidates for CD4 T cell pathogenicity in experimental neuroinflammation and multiple sclerosis
-
Hoppmann N., Graetz C., Paterka M., et al. New candidates for CD4 T cell pathogenicity in experimental neuroinflammation and multiple sclerosis. Brain: 2015; 138 (Pt 4): 902 917
-
(2015)
Brain
, vol.138
, Issue.PART 4
, pp. 902-917
-
-
Hoppmann, N.1
Graetz, C.2
Paterka, M.3
-
99
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
Viglietta V., Baecher-Allan C., Weiner H. L., Hafler D. A. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med: 2004; 199 7 971 979
-
(2004)
J Exp Med
, vol.199
, Issue.7
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
100
-
-
27944499757
-
Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis
-
Haas J., Hug A., Viehöver A., et al. Reduced suppressive effect of CD4+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis. Eur J Immunol: 2005; 35 11 3343 3352
-
(2005)
Eur J Immunol
, vol.35
, Issue.11
, pp. 3343-3352
-
-
Haas, J.1
Hug, A.2
Viehöver, A.3
-
101
-
-
79958134797
-
Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease
-
Dominguez-Villar M., Baecher-Allan C. M., Hafler D. A. Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease. Nat Med: 2011; 17 6 673 675
-
(2011)
Nat Med
, vol.17
, Issue.6
, pp. 673-675
-
-
Dominguez-Villar, M.1
Baecher-Allan, C.M.2
Hafler, D.A.3
-
102
-
-
79953215997
-
CD2 costimulation reveals defective activity by human CD4+CD25(hi) regulatory cells in patients with multiple sclerosis
-
Baecher-Allan C. M., Costantino C. M., Cvetanovich G. L., et al. CD2 costimulation reveals defective activity by human CD4+CD25(hi) regulatory cells in patients with multiple sclerosis. J Immunol: 2011; 186 6 3317 3326
-
(2011)
J Immunol
, vol.186
, Issue.6
, pp. 3317-3326
-
-
Baecher-Allan, C.M.1
Costantino, C.M.2
Cvetanovich, G.L.3
-
103
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Zheng Y., Josefowicz S. Z., Kas A., Chu T. T., Gavin M. A., Rudensky A. Y. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature: 2007; 445 7130 936 940
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 936-940
-
-
Zheng, Y.1
Josefowicz, S.Z.2
Kas, A.3
Chu, T.T.4
Gavin, M.A.5
Rudensky, A.Y.6
-
104
-
-
33847242598
-
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
-
Marson A., Kretschmer K., Frampton G. M., et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature: 2007; 445 7130 931 935
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 931-935
-
-
Marson, A.1
Kretschmer, K.2
Frampton, G.M.3
-
105
-
-
84930809027
-
Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli
-
Housley W. J., Fernandez S. D., Vera K., et al. Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli. Sci Transl Med: 2015; 7 291 291ra93
-
(2015)
Sci Transl Med
, vol.7
, Issue.291
, pp. 291ra93
-
-
Housley, W.J.1
Fernandez, S.D.2
Vera, K.3
-
106
-
-
84921342055
-
Neutrophil-related factors as biomarkers in EAE and MS
-
Rumble J. M., Huber A. K., Krishnamoorthy G., et al. Neutrophil-related factors as biomarkers in EAE and MS. J Exp Med: 2015; 212 1 23 35
-
(2015)
J Exp Med
, vol.212
, Issue.1
, pp. 23-35
-
-
Rumble, J.M.1
Huber, A.K.2
Krishnamoorthy, G.3
-
107
-
-
84856804751
-
Neutrophils in multiple sclerosis are characterized by a primed phenotype
-
Naegele M., Tillack K., Reinhardt S., Schippling S., Martin R., Sospedra M. Neutrophils in multiple sclerosis are characterized by a primed phenotype. J Neuroimmunol: 2012; 242 1-2 60 71
-
(2012)
J Neuroimmunol
, vol.242
, Issue.12
, pp. 60-71
-
-
Naegele, M.1
Tillack, K.2
Reinhardt, S.3
Schippling, S.4
Martin, R.5
Sospedra, M.6
-
108
-
-
0034643935
-
Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor
-
Openshaw H., Stuve O., Antel J. P., et al. Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor. Neurology: 2000; 54 11 2147 2150
-
(2000)
Neurology
, vol.54
, Issue.11
, pp. 2147-2150
-
-
Openshaw, H.1
Stuve, O.2
Antel, J.P.3
-
109
-
-
84859404847
-
T lymphocyte priming by neutrophil extracellular traps links innate and adaptive immune responses
-
Tillack K., Breiden P., Martin R., Sospedra M. T lymphocyte priming by neutrophil extracellular traps links innate and adaptive immune responses. J Immunol: 2012; 188 7 3150 3159
-
(2012)
J Immunol
, vol.188
, Issue.7
, pp. 3150-3159
-
-
Tillack, K.1
Breiden, P.2
Martin, R.3
Sospedra, M.4
-
110
-
-
0343618469
-
Differential expression of NK T cell v alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy
-
Illés Z., Kondo T., Newcombe J., Oka N., Tabira T., Yamamura T. Differential expression of NK T cell V alpha 24J alpha Q invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. J Immunol: 2000; 164 8 4375 4381
-
(2000)
J Immunol
, vol.164
, Issue.8
, pp. 4375-4381
-
-
Illés, Z.1
Kondo, T.2
Newcombe, J.3
Oka, N.4
Tabira, T.5
Yamamura, T.6
-
111
-
-
84877631908
-
Invariant natural killer T-cell anergy to endogenous myelin acetyl-glycolipids in multiple sclerosis
-
Gately C. M., Podbielska M., Counihan T., et al. Invariant natural killer T-cell anergy to endogenous myelin acetyl-glycolipids in multiple sclerosis. J Neuroimmunol: 2013; 259 1-2 1 7
-
(2013)
J Neuroimmunol
, vol.259
, Issue.12
, pp. 1-7
-
-
Gately, C.M.1
Podbielska, M.2
Counihan, T.3
-
112
-
-
79551700235
-
CD161(high)CD8+T cells bear pathogenetic potential in multiple sclerosis
-
Annibali V., Ristori G., Angelini D. F., et al. CD161(high)CD8+T cells bear pathogenetic potential in multiple sclerosis. Brain: 2011; 134 (Pt 2): 542 554
-
(2011)
Brain
, vol.134
, Issue.PART 2
, pp. 542-554
-
-
Annibali, V.1
Ristori, G.2
Angelini, D.F.3
-
113
-
-
84883442367
-
Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis
-
Abrahamsson S. V., Angelini D. F., Dubinsky A. N., et al. Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis. Brain: 2013; 136 (Pt 9): 2888 2903
-
(2013)
Brain
, vol.136
, Issue.PART 9
, pp. 2888-2903
-
-
Abrahamsson, S.V.1
Angelini, D.F.2
Dubinsky, A.N.3
-
114
-
-
84923179779
-
+ MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis
-
+ MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis. Eur J Immunol: 2014; 44 10 3119 3128
-
(2014)
Eur J Immunol
, vol.44
, Issue.10
, pp. 3119-3128
-
-
Willing, A.1
Leach, O.A.2
Ufer, F.3
-
115
-
-
84944416146
-
T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis
-
Held K., Beltrán E., Moser M., Hohlfeld R., Dornmair K. T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis. Hum Immunol: 2015; 76 9 607 614
-
(2015)
Hum Immunol
, vol.76
, Issue.9
, pp. 607-614
-
-
Held, K.1
Beltrán, E.2
Moser, M.3
Hohlfeld, R.4
Dornmair, K.5
-
116
-
-
0032526195
-
A role for natural killer cells in the immunopathogenesis of multiple sclerosis
-
Kastrukoff L. F., Morgan N. G., Zecchini D., et al. A role for natural killer cells in the immunopathogenesis of multiple sclerosis. J Neuroimmunol: 1998; 86 2 123 133
-
(1998)
J Neuroimmunol
, vol.86
, Issue.2
, pp. 123-133
-
-
Kastrukoff, L.F.1
Morgan, N.G.2
Zecchini, D.3
-
117
-
-
2942537826
-
Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta
-
Bielekova B., Richert N., Howard T., et al. Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. Proc Natl Acad Sci U S A: 2004; 101 23 8705 8708
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.23
, pp. 8705-8708
-
-
Bielekova, B.1
Richert, N.2
Howard, T.3
-
118
-
-
33645812129
-
Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis
-
Bielekova B., Catalfamo M., Reichert-Scrivner S., et al. Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis. Proc Natl Acad Sci U S A: 2006; 103 15 5941 5946
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.15
, pp. 5941-5946
-
-
Bielekova, B.1
Catalfamo, M.2
Reichert-Scrivner, S.3
-
119
-
-
0001435965
-
An electrophoretic study of the protein components in cerebrospinal fluid and their relationship to the serum proteins
-
Kabat E. A., Moore D. H., Landow H. An electrophoretic study of the protein components in cerebrospinal fluid and their relationship to the serum proteins. J Clin Invest: 1942; 21 5 571 577
-
(1942)
J Clin Invest
, vol.21
, Issue.5
, pp. 571-577
-
-
Kabat, E.A.1
Moore, D.H.2
Landow, H.3
-
120
-
-
0038790058
-
Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event
-
Berger T., Rubner P., Schautzer F., et al. Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event. N Engl J Med: 2003; 349 2 139 145
-
(2003)
N Engl J Med
, vol.349
, Issue.2
, pp. 139-145
-
-
Berger, T.1
Rubner, P.2
Schautzer, F.3
-
121
-
-
80053300042
-
Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis
-
Pröbstel A. K., Dornmair K., Bittner R., et al. Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology: 2011; 77 6 580 588
-
(2011)
Neurology
, vol.77
, Issue.6
, pp. 580-588
-
-
Pröbstel, A.K.1
Dornmair, K.2
Bittner, R.3
-
122
-
-
84865611092
-
Anti-myelin oligodendrocyte glycoprotein antibodies in pediatric patients with optic neuritis
-
Rostasy K., Mader S., Schanda K., et al. Anti-myelin oligodendrocyte glycoprotein antibodies in pediatric patients with optic neuritis. Arch Neurol: 2012; 69 6 752 756
-
(2012)
Arch Neurol
, vol.69
, Issue.6
, pp. 752-756
-
-
Rostasy, K.1
Mader, S.2
Schanda, K.3
-
123
-
-
84926656859
-
Antibodies to myelin oligodendrocyte glycoprotein in idiopathic optic neuritis
-
Nakajima H., Motomura M., Tanaka K., et al. Antibodies to myelin oligodendrocyte glycoprotein in idiopathic optic neuritis. BMJ Open: 2015; 5 4 e007766
-
(2015)
BMJ Open
, vol.5
, Issue.4
, pp. e007766
-
-
Nakajima, H.1
Motomura, M.2
Tanaka, K.3
-
124
-
-
84868525833
-
B cells and antibodies in multiple sclerosis pathogenesis and therapy
-
Krumbholz M., Derfuss T., Hohlfeld R., Meinl E. B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nat Rev Neurol: 2012; 8 11 613 623
-
(2012)
Nat Rev Neurol
, vol.8
, Issue.11
, pp. 613-623
-
-
Krumbholz, M.1
Derfuss, T.2
Hohlfeld, R.3
Meinl, E.4
-
125
-
-
84863649686
-
Potassium channel KIR4.1 as an immune target in multiple sclerosis
-
Srivastava R., Aslam M., Kalluri S. R., et al. Potassium channel KIR4.1 as an immune target in multiple sclerosis. N Engl J Med: 2012; 367 2 115 123
-
(2012)
N Engl J Med
, vol.367
, Issue.2
, pp. 115-123
-
-
Srivastava, R.1
Aslam, M.2
Kalluri, S.R.3
-
126
-
-
34948864286
-
Neurofascin as a novel target for autoantibody-mediated axonal injury
-
Mathey E. K., Derfuss T., Storch M. K., et al. Neurofascin as a novel target for autoantibody-mediated axonal injury. J Exp Med: 2007; 204 10 2363 2372
-
(2007)
J Exp Med
, vol.204
, Issue.10
, pp. 2363-2372
-
-
Mathey, E.K.1
Derfuss, T.2
Storch, M.K.3
-
127
-
-
66249105681
-
Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals
-
Derfuss T., Parikh K., Velhin S., et al. Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proc Natl Acad Sci U S A: 2009; 106 20 8302 8307
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.20
, pp. 8302-8307
-
-
Derfuss, T.1
Parikh, K.2
Velhin, S.3
-
128
-
-
84861556651
-
Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis
-
Elliott C., Lindner M., Arthur A., et al. Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain: 2012; 135 (Pt 6): 1819 1833
-
(2012)
Brain
, vol.135
, Issue.PART 6
, pp. 1819-1833
-
-
Elliott, C.1
Lindner, M.2
Arthur, A.3
-
129
-
-
0033710540
-
The myelin oligodendrocyte glycoprotein (MOG): A model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis
-
Stefferl A., Brehm U., Linington C. The myelin oligodendrocyte glycoprotein (MOG): a model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis. J Neural Transm Suppl: 2000; 58 58 123 133
-
(2000)
J Neural Transm Suppl
, vol.58
, Issue.58
, pp. 123-133
-
-
Stefferl, A.1
Brehm, U.2
Linington, C.3
-
130
-
-
85047691237
-
Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS
-
Villar L. M., Sádaba M. C., Roldán E., et al. Intrathecal synthesis of oligoclonal IgM against myelin lipids predicts an aggressive disease course in MS. J Clin Invest: 2005; 115 1 187 194
-
(2005)
J Clin Invest
, vol.115
, Issue.1
, pp. 187-194
-
-
Villar, L.M.1
Sádaba, M.C.2
Roldán, E.3
-
131
-
-
34249700046
-
Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology
-
Magliozzi R., Howell O., Vora A., et al. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain: 2007; 130 (Pt 4): 1089 1104
-
(2007)
Brain
, vol.130
, Issue.PART 4
, pp. 1089-1104
-
-
Magliozzi, R.1
Howell, O.2
Vora, A.3
-
133
-
-
36549034729
-
Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain
-
Serafini B., Rosicarelli B., Franciotta D., et al. Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain. J Exp Med: 2007; 204 12 2899 2912
-
(2007)
J Exp Med
, vol.204
, Issue.12
, pp. 2899-2912
-
-
Serafini, B.1
Rosicarelli, B.2
Franciotta, D.3
-
134
-
-
84879977301
-
Radioactive in situ hybridization for Epstein-Barr virus-encoded small RNA supports presence of Epstein-Barr virus in the multiple sclerosis brain
-
Serafini B., Muzio L., Rosicarelli B., Aloisi F. Radioactive in situ hybridization for Epstein-Barr virus-encoded small RNA supports presence of Epstein-Barr virus in the multiple sclerosis brain. Brain: 2013; 136 (Pt 7): e233
-
(2013)
Brain
, vol.136
, Issue.PART 7
, pp. e233
-
-
Serafini, B.1
Muzio, L.2
Rosicarelli, B.3
Aloisi, F.4
-
135
-
-
80052959919
-
Epstein-Barr virus in the multiple sclerosis brain: A controversial issue-report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria
-
NeuroproMiSe EBV Working Group. (Pt 9
-
Lassmann H., Niedobitek G., Aloisi F., Middeldorp J. M.; NeuroproMiSe EBV Working Group. Epstein-Barr virus in the multiple sclerosis brain: a controversial issue-report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria. Brain: 2011; 134 (Pt 9): 2772 2786
-
(2011)
Brain
, vol.134
, pp. 2772-2786
-
-
Lassmann, H.1
Niedobitek, G.2
Aloisi, F.3
Middeldorp, J.M.4
-
136
-
-
80052927697
-
Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
-
Howell O. W., Reeves C. A., Nicholas R., et al. Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis. Brain: 2011; 134 (Pt 9): 2755 2771
-
(2011)
Brain
, vol.134
, Issue.PART 9
, pp. 2755-2771
-
-
Howell, O.W.1
Reeves, C.A.2
Nicholas, R.3
-
137
-
-
84890599669
-
Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats
-
Gardner C., Magliozzi R., Durrenberger P. F., Howell O. W., Rundle J., Reynolds R. Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats. Brain: 2013; 136 (Pt 12): 3596 3608
-
(2013)
Brain
, vol.136
, Issue.PART 12
, pp. 3596-3608
-
-
Gardner, C.1
Magliozzi, R.2
Durrenberger, P.F.3
Howell, O.W.4
Rundle, J.5
Reynolds, R.6
-
138
-
-
84905967681
-
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
-
Stern J. N., Yaari G., Vander Heiden J. A., et al. B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes. Sci Transl Med: 2014; 6 248 248ra107
-
(2014)
Sci Transl Med
, vol.6
, Issue.248
, pp. 248ra107
-
-
Stern, J.N.1
Yaari, G.2
Vander Heiden, J.A.3
-
139
-
-
84870498631
-
B cell exchange across the blood-brain barrier in multiple sclerosis
-
von Büdingen H. C., Kuo T. C., Sirota M., et al. B cell exchange across the blood-brain barrier in multiple sclerosis. J Clin Invest: 2012; 122 12 4533 4543
-
(2012)
J Clin Invest
, vol.122
, Issue.12
, pp. 4533-4543
-
-
Von Büdingen, H.C.1
Kuo, T.C.2
Sirota, M.3
-
140
-
-
84905988500
-
Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis
-
Palanichamy A., Apeltsin L., Kuo T. C., et al. Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis. Sci Transl Med: 2014; 6 248 248ra106
-
(2014)
Sci Transl Med
, vol.6
, Issue.248
, pp. 248ra106
-
-
Palanichamy, A.1
Apeltsin, L.2
Kuo, T.C.3
-
141
-
-
39049142995
-
B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
-
HERMES Trial Group
-
Hauser S. L., Waubant E., Arnold D. L., et al. HERMES Trial Group. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med: 2008; 358 7 676 688
-
(2008)
N Engl J Med
, vol.358
, Issue.7
, pp. 676-688
-
-
Hauser, S.L.1
Waubant, E.2
Arnold, D.L.3
-
142
-
-
84988372229
-
Efficacy and safety of ocrelizumab in relapsing multiple sclerosis-results of the interferon-beta-1a-controlled, double-blind, phase III OPERA i and II studies
-
Hauser S. L., Comi G. C., Hartung H. P., et al. Efficacy and safety of ocrelizumab in relapsing multiple sclerosis-results of the interferon-beta-1a-controlled, double-blind, phase III OPERA I and II studies. ECTRIMS Online Library 2015; 116634
-
ECTRIMS Online Library 2015
, pp. 116634
-
-
Hauser, S.L.1
Comi, G.C.2
Hartung, H.P.3
-
143
-
-
43249103954
-
Getting specific: Monoclonal antibodies in multiple sclerosis
-
Lutterotti A., Martin R. Getting specific: monoclonal antibodies in multiple sclerosis. Lancet Neurol: 2008; 7 6 538 547
-
(2008)
Lancet Neurol
, vol.7
, Issue.6
, pp. 538-547
-
-
Lutterotti, A.1
Martin, R.2
-
144
-
-
84945538148
-
Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy
-
Canadian B cells in MS Team
-
Li R., Rezk A., Miyazaki Y., et al. Canadian B cells in MS Team. Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy. Sci Transl Med: 2015; 7 310 310ra166
-
(2015)
Sci Transl Med
, vol.7
, Issue.310
, pp. 310ra166
-
-
Li, R.1
Rezk, A.2
Miyazaki, Y.3
-
145
-
-
84896041306
-
From the regulatory functions of B cells to the identification of cytokine-producing plasma cell subsets
-
Dang V. D., Hilgenberg E., Ries S., Shen P., Fillatreau S. From the regulatory functions of B cells to the identification of cytokine-producing plasma cell subsets. Curr Opin Immunol: 2014; 28 77 83
-
(2014)
Curr Opin Immunol
, vol.28
, pp. 77-83
-
-
Dang, V.D.1
Hilgenberg, E.2
Ries, S.3
Shen, P.4
Fillatreau, S.5
-
146
-
-
84869885852
-
Capture, crawl, cross: The T cell code to breach the blood-brain barriers
-
Engelhardt B., Ransohoff R. M. Capture, crawl, cross: the T cell code to breach the blood-brain barriers. Trends Immunol: 2012; 33 12 579 589
-
(2012)
Trends Immunol
, vol.33
, Issue.12
, pp. 579-589
-
-
Engelhardt, B.1
Ransohoff, R.M.2
-
147
-
-
0037816192
-
Human cerebrospinal fluid central memory CD4+ T cells: Evidence for trafficking through choroid plexus and meninges via P-selectin
-
Kivisäkk P., Mahad D. J., Callahan M. K., et al. Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin. Proc Natl Acad Sci U S A: 2003; 100 14 8389 8394
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.14
, pp. 8389-8394
-
-
Kivisäkk, P.1
Mahad, D.J.2
Callahan, M.K.3
-
148
-
-
65649096159
-
Localizing central nervous system immune surveillance: Meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis
-
Kivisäkk P., Imitola J., Rasmussen S., et al. Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann Neurol: 2009; 65 4 457 469
-
(2009)
Ann Neurol
, vol.65
, Issue.4
, pp. 457-469
-
-
Kivisäkk, P.1
Imitola, J.2
Rasmussen, S.3
-
149
-
-
16244380177
-
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
-
Greter M., Heppner F. L., Lemos M. P., et al. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat Med: 2005; 11 3 328 334
-
(2005)
Nat Med
, vol.11
, Issue.3
, pp. 328-334
-
-
Greter, M.1
Heppner, F.L.2
Lemos, M.P.3
-
150
-
-
20044376483
-
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
-
Heppner F. L., Greter M., Marino D., et al. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med: 2005; 11 2 146 152
-
(2005)
Nat Med
, vol.11
, Issue.2
, pp. 146-152
-
-
Heppner, F.L.1
Greter, M.2
Marino, D.3
-
151
-
-
34247108119
-
Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis
-
Brown D. A., Sawchenko P. E. Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis. J Comp Neurol: 2007; 502 2 236 260
-
(2007)
J Comp Neurol
, vol.502
, Issue.2
, pp. 236-260
-
-
Brown, D.A.1
Sawchenko, P.E.2
-
152
-
-
0026506799
-
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
-
Yednock T. A., Cannon C., Fritz L. C., Sanchez-Madrid F., Steinman L., Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature: 1992; 356 6364 63 66
-
(1992)
Nature
, vol.356
, Issue.6364
, pp. 63-66
-
-
Yednock, T.A.1
Cannon, C.2
Fritz, L.C.3
Sanchez-Madrid, F.4
Steinman, L.5
Karin, N.6
-
153
-
-
23844467851
-
Therapeutic targeting of alpha 4-integrins in chronic inflammatory diseases: Tipping the scales of risk towards benefit?
-
Engelhardt B., Briskin M. J. Therapeutic targeting of alpha 4-integrins in chronic inflammatory diseases: tipping the scales of risk towards benefit? Eur J Immunol: 2005; 35 8 2268 2273
-
(2005)
Eur J Immunol
, vol.35
, Issue.8
, pp. 2268-2273
-
-
Engelhardt, B.1
Briskin, M.J.2
-
154
-
-
61549130275
-
Effect of plasma exchange in accelerating natalizumab clearance and restoring leukocyte function
-
Khatri B. O., Man S., Giovannoni G., et al. Effect of plasma exchange in accelerating natalizumab clearance and restoring leukocyte function. Neurology: 2009; 72 5 402 409
-
(2009)
Neurology
, vol.72
, Issue.5
, pp. 402-409
-
-
Khatri, B.O.1
Man, S.2
Giovannoni, G.3
-
155
-
-
67349218765
-
Alpha4 integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions
-
Man S., Tucky B., Bagheri N., Li X., Kochar R., Ransohoff R. M. Alpha4 integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions. J Neuroimmunol: 2009; 210 1-2 92 99
-
(2009)
J Neuroimmunol
, vol.210
, Issue.12
, pp. 92-99
-
-
Man, S.1
Tucky, B.2
Bagheri, N.3
Li, X.4
Kochar, R.5
Ransohoff, R.M.6
-
156
-
-
70350718157
-
Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis
-
Coisne C., Mao W., Engelhardt B. Cutting edge: natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis. J Immunol: 2009; 182 10 5909 5913
-
(2009)
J Immunol
, vol.182
, Issue.10
, pp. 5909-5913
-
-
Coisne, C.1
Mao, W.2
Engelhardt, B.3
-
157
-
-
70449525704
-
Chemokines and chemokine receptors: Standing at the crossroads of immunobiology and neurobiology
-
Ransohoff R. M. Chemokines and chemokine receptors: standing at the crossroads of immunobiology and neurobiology. Immunity: 2009; 31 5 711 721
-
(2009)
Immunity
, vol.31
, Issue.5
, pp. 711-721
-
-
Ransohoff, R.M.1
-
158
-
-
65249175159
-
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
-
Reboldi A., Coisne C., Baumjohann D., et al. C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat Immunol: 2009; 10 5 514 523
-
(2009)
Nat Immunol
, vol.10
, Issue.5
, pp. 514-523
-
-
Reboldi, A.1
Coisne, C.2
Baumjohann, D.3
-
159
-
-
84855475637
-
Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE
-
Rothhammer V., Heink S., Petermann F., et al. Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE. J Exp Med: 2011; 208 12 2465 2476
-
(2011)
J Exp Med
, vol.208
, Issue.12
, pp. 2465-2476
-
-
Rothhammer, V.1
Heink, S.2
Petermann, F.3
-
160
-
-
1642458745
-
The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis
-
Kawakami N., Lassmann S., Li Z., et al. The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. J Exp Med: 2004; 199 2 185 197
-
(2004)
J Exp Med
, vol.199
, Issue.2
, pp. 185-197
-
-
Kawakami, N.1
Lassmann, S.2
Li, Z.3
-
161
-
-
70449106029
-
Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
-
Bartholomäus I., Kawakami N., Odoardi F., et al. Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature: 2009; 462 7269 94 98
-
(2009)
Nature
, vol.462
, Issue.7269
, pp. 94-98
-
-
Bartholomäus, I.1
Kawakami, N.2
Odoardi, F.3
-
162
-
-
33846918610
-
Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: Implications for locomotion and the multistep paradigm
-
Schreiber T. H., Shinder V., Cain D. W., Alon R., Sackstein R. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm. Blood: 2007; 109 4 1381 1386
-
(2007)
Blood
, vol.109
, Issue.4
, pp. 1381-1386
-
-
Schreiber, T.H.1
Shinder, V.2
Cain, D.W.3
Alon, R.4
Sackstein, R.5
-
163
-
-
58149352396
-
Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis
-
Kim J. V., Kang S. S., Dustin M. L., McGavern D. B. Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis. Nature: 2009; 457 7226 191 195
-
(2009)
Nature
, vol.457
, Issue.7226
, pp. 191-195
-
-
Kim, J.V.1
Kang, S.S.2
Dustin, M.L.3
McGavern, D.B.4
-
164
-
-
0031002545
-
Axonal damage in acute multiple sclerosis lesions
-
Ferguson B., Matyszak M. K., Esiri M. M., Perry V. H. Axonal damage in acute multiple sclerosis lesions. Brain: 1997; 120 (Pt 3): 393 399
-
(1997)
Brain
, vol.120
, Issue.PART 3
, pp. 393-399
-
-
Ferguson, B.1
Matyszak, M.K.2
Esiri, M.M.3
Perry, V.H.4
-
165
-
-
0030002224
-
A novel population of CD4+CD56+ myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule
-
Vergelli M., Le H., van Noort J. M., Dhib-Jalbut S., McFarland H., Martin R. A novel population of CD4+CD56+ myelin-reactive T cells lyses target cells expressing CD56/neural cell adhesion molecule. J Immunol: 1996; 157 2 679 688
-
(1996)
J Immunol
, vol.157
, Issue.2
, pp. 679-688
-
-
Vergelli, M.1
Le, H.2
Van Noort, J.M.3
Dhib-Jalbut, S.4
McFarland, H.5
Martin, R.6
-
166
-
-
0031569102
-
Human autoreactive CD4+ T cell clones use perforin- or Fas/Fas ligand-mediated pathways for target cell lysis
-
Vergelli M., Hemmer B., Muraro P. A., et al. Human autoreactive CD4+ T cell clones use perforin- or Fas/Fas ligand-mediated pathways for target cell lysis. J Immunol: 1997; 158 6 2756 2761
-
(1997)
J Immunol
, vol.158
, Issue.6
, pp. 2756-2761
-
-
Vergelli, M.1
Hemmer, B.2
Muraro, P.A.3
-
167
-
-
0032519963
-
Non-MHC-restricted cell-mediated lysis of human oligodendrocytes in vitro: Relation with CD56 expression
-
Antel J. P., McCrea E., Ladiwala U., Qin Y. F., Becher B. Non-MHC-restricted cell-mediated lysis of human oligodendrocytes in vitro: relation with CD56 expression. J Immunol: 1998; 160 4 1606 1611
-
(1998)
J Immunol
, vol.160
, Issue.4
, pp. 1606-1611
-
-
Antel, J.P.1
McCrea, E.2
Ladiwala, U.3
Qin, Y.F.4
Becher, B.5
-
168
-
-
84874826127
-
Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosis
-
Zaguia F., Saikali P., Ludwin S., et al. Cytotoxic NKG2C+ CD4 T cells target oligodendrocytes in multiple sclerosis. J Immunol: 2013; 190 6 2510 2518
-
(2013)
J Immunol
, vol.190
, Issue.6
, pp. 2510-2518
-
-
Zaguia, F.1
Saikali, P.2
Ludwin, S.3
-
169
-
-
20944446609
-
Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL
-
Aktas O., Smorodchenko A., Brocke S., et al. Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL. Neuron: 2005; 46 3 421 432
-
(2005)
Neuron
, vol.46
, Issue.3
, pp. 421-432
-
-
Aktas, O.1
Smorodchenko, A.2
Brocke, S.3
-
170
-
-
33644799988
-
TRAIL-induced death of human adult oligodendrocytes is mediated by JNK pathway
-
Jurewicz A., Matysiak M., Andrzejak S., Selmaj K. TRAIL-induced death of human adult oligodendrocytes is mediated by JNK pathway. Glia: 2006; 53 2 158 166
-
(2006)
Glia
, vol.53
, Issue.2
, pp. 158-166
-
-
Jurewicz, A.1
Matysiak, M.2
Andrzejak, S.3
Selmaj, K.4
-
171
-
-
0028059276
-
Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes
-
Suidan H. S., Bouvier J., Schaerer E., Stone S. R., Monard D., Tschopp J. Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes. Proc Natl Acad Sci U S A: 1994; 91 17 8112 8116
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, Issue.17
, pp. 8112-8116
-
-
Suidan, H.S.1
Bouvier, J.2
Schaerer, E.3
Stone, S.R.4
Monard, D.5
Tschopp, J.6
-
172
-
-
0023904746
-
Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
-
Selmaj K. W., Raine C. S. Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol: 1988; 23 4 339 346
-
(1988)
Ann Neurol
, vol.23
, Issue.4
, pp. 339-346
-
-
Selmaj, K.W.1
Raine, C.S.2
-
173
-
-
33751116843
-
Interferon-gamma induced nitric oxide mediates in vitro neuronal damage by Trypanosoma cruzi-infected macrophages
-
Almeida-Leite C. M., Galvão L. M., Afonso L. C., Cunha F. Q., Arantes R. M. Interferon-gamma induced nitric oxide mediates in vitro neuronal damage by Trypanosoma cruzi-infected macrophages. Neurobiol Dis: 2007; 25 1 170 178
-
(2007)
Neurobiol Dis
, vol.25
, Issue.1
, pp. 170-178
-
-
Almeida-Leite, C.M.1
Galvão, L.M.2
Afonso, L.C.3
Cunha, F.Q.4
Arantes, R.M.5
-
174
-
-
1842663407
-
Interferon-gamma but not TNF alpha promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells
-
Wong G., Goldshmit Y., Turnley A. M. Interferon-gamma but not TNF alpha promotes neuronal differentiation and neurite outgrowth of murine adult neural stem cells. Exp Neurol: 2004; 187 1 171 177
-
(2004)
Exp Neurol
, vol.187
, Issue.1
, pp. 171-177
-
-
Wong, G.1
Goldshmit, Y.2
Turnley, A.M.3
-
175
-
-
58149159798
-
Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis
-
Lees J. R., Golumbek P. T., Sim J., Dorsey D., Russell J. H. Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis. J Exp Med: 2008; 205 11 2633 2642
-
(2008)
J Exp Med
, vol.205
, Issue.11
, pp. 2633-2642
-
-
Lees, J.R.1
Golumbek, P.T.2
Sim, J.3
Dorsey, D.4
Russell, J.H.5
-
176
-
-
46949104323
-
IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
Kroenke M. A., Carlson T. J., Andjelkovic A. V., Segal B. M. IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med: 2008; 205 7 1535 1541
-
(2008)
J Exp Med
, vol.205
, Issue.7
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
177
-
-
84923629275
-
Exploring the origins of grey matter damage in multiple sclerosis
-
Calabrese M., Magliozzi R., Ciccarelli O., Geurts J. J., Reynolds R., Martin R. Exploring the origins of grey matter damage in multiple sclerosis. Nat Rev Neurosci: 2015; 16 3 147 158
-
(2015)
Nat Rev Neurosci
, vol.16
, Issue.3
, pp. 147-158
-
-
Calabrese, M.1
Magliozzi, R.2
Ciccarelli, O.3
Geurts, J.J.4
Reynolds, R.5
Martin, R.6
-
178
-
-
83155173565
-
Inflammatory cortical demyelination in early multiple sclerosis
-
Lucchinetti C. F., Popescu B. F., Bunyan R. F., et al. Inflammatory cortical demyelination in early multiple sclerosis. N Engl J Med: 2011; 365 23 2188 2197
-
(2011)
N Engl J Med
, vol.365
, Issue.23
, pp. 2188-2197
-
-
Lucchinetti, C.F.1
Popescu, B.F.2
Bunyan, R.F.3
-
179
-
-
37549070224
-
Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection
-
Zeis T., Graumann U., Reynolds R., Schaeren-Wiemers N. Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. Brain: 2008; 131 (Pt 1): 288 303
-
(2008)
Brain
, vol.131
, Issue.PART 1
, pp. 288-303
-
-
Zeis, T.1
Graumann, U.2
Reynolds, R.3
Schaeren-Wiemers, N.4
-
180
-
-
0242667881
-
Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult
-
Graumann U., Reynolds R., Steck A. J., Schaeren-Wiemers N. Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult. Brain Pathol: 2003; 13 4 554 573
-
(2003)
Brain Pathol
, vol.13
, Issue.4
, pp. 554-573
-
-
Graumann, U.1
Reynolds, R.2
Steck, A.J.3
Schaeren-Wiemers, N.4
-
181
-
-
20444489863
-
The spectrum of multiple sclerosis: New lessons from pathology
-
Brück W., Stadelmann C. The spectrum of multiple sclerosis: new lessons from pathology. Curr Opin Neurol: 2005; 18 3 221 224
-
(2005)
Curr Opin Neurol
, vol.18
, Issue.3
, pp. 221-224
-
-
Brück, W.1
Stadelmann, C.2
-
182
-
-
84884907805
-
Pathology and disease mechanisms in different stages of multiple sclerosis
-
Lassmann H. Pathology and disease mechanisms in different stages of multiple sclerosis. J Neurol Sci: 2013; 333 1-2 1 4
-
(2013)
J Neurol Sci
, vol.333
, Issue.12
, pp. 1-4
-
-
Lassmann, H.1
-
183
-
-
84922485376
-
Pathological mechanisms in progressive multiple sclerosis
-
Mahad D. H., Trapp B. D., Lassmann H. Pathological mechanisms in progressive multiple sclerosis. Lancet Neurol: 2015; 14 2 183 193
-
(2015)
Lancet Neurol
, vol.14
, Issue.2
, pp. 183-193
-
-
Mahad, D.H.1
Trapp, B.D.2
Lassmann, H.3
-
184
-
-
33845302957
-
Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis
-
Astier A. L., Meiffren G., Freeman S., Hafler D. A. Alterations in CD46-mediated Tr1 regulatory T cells in patients with multiple sclerosis. J Clin Invest: 2006; 116 12 3252 3257
-
(2006)
J Clin Invest
, vol.116
, Issue.12
, pp. 3252-3257
-
-
Astier, A.L.1
Meiffren, G.2
Freeman, S.3
Hafler, D.A.4
-
185
-
-
33744904725
-
Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
-
Venken K., Hellings N., Hensen K., et al. Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression. J Neurosci Res: 2006; 83 8 1432 1446
-
(2006)
J Neurosci Res
, vol.83
, Issue.8
, pp. 1432-1446
-
-
Venken, K.1
Hellings, N.2
Hensen, K.3
-
186
-
-
44449171488
-
Natural naive CD4+CD25+CD127low regulatory T cell (Treg) development and function are disturbed in multiple sclerosis patients: Recovery of memory Treg homeostasis during disease progression
-
Venken K., Hellings N., Broekmans T., Hensen K., Rummens J. L., Stinissen P. Natural naive CD4+CD25+CD127low regulatory T cell (Treg) development and function are disturbed in multiple sclerosis patients: recovery of memory Treg homeostasis during disease progression. J Immunol: 2008; 180 9 6411 6420
-
(2008)
J Immunol
, vol.180
, Issue.9
, pp. 6411-6420
-
-
Venken, K.1
Hellings, N.2
Broekmans, T.3
Hensen, K.4
Rummens, J.L.5
Stinissen, P.6
-
187
-
-
43649095467
-
CD127 immunophenotyping suggests altered CD4+ T cell regulation in primary progressive multiple sclerosis
-
McKay F. C., Swain L. I., Schibeci S. D., et al. CD127 immunophenotyping suggests altered CD4+ T cell regulation in primary progressive multiple sclerosis. J Autoimmun: 2008; 31 1 52 58
-
(2008)
J Autoimmun
, vol.31
, Issue.1
, pp. 52-58
-
-
McKay, F.C.1
Swain, L.I.2
Schibeci, S.D.3
-
188
-
-
84931365086
-
TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: A novel mechanism of reduced regulatory T cell function in multiple sclerosis
-
Nyirenda M. H., Morandi E., Vinkemeier U., et al. TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: a novel mechanism of reduced regulatory T cell function in multiple sclerosis. J Immunol: 2015; 194 12 5761 5774
-
(2015)
J Immunol
, vol.194
, Issue.12
, pp. 5761-5774
-
-
Nyirenda, M.H.1
Morandi, E.2
Vinkemeier, U.3
-
189
-
-
84941361355
-
Melatonin contributes to the seasonality of multiple sclerosis relapses
-
Farez M. F., Mascanfroni I. D., Méndez-Huergo S. P., et al. Melatonin contributes to the seasonality of multiple sclerosis relapses. Cell: 2015; 162 6 1338 1352
-
(2015)
Cell
, vol.162
, Issue.6
, pp. 1338-1352
-
-
Farez, M.F.1
Mascanfroni, I.D.2
Méndez-Huergo, S.P.3
-
190
-
-
84943562782
-
Daclizumab HYP versus interferon beta-1a in relapsing multiple sclerosis
-
Kappos L., Wiendl H., Selmaj K., et al. Daclizumab HYP versus interferon beta-1a in relapsing multiple sclerosis. N Engl J Med: 2015; 373 15 1418 1428
-
(2015)
N Engl J Med
, vol.373
, Issue.15
, pp. 1418-1428
-
-
Kappos, L.1
Wiendl, H.2
Selmaj, K.3
-
191
-
-
65249138318
-
Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis
-
Bielekova B., Howard T., Packer A. N., et al. Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis. Arch Neurol: 2009; 66 4 483 489
-
(2009)
Arch Neurol
, vol.66
, Issue.4
, pp. 483-489
-
-
Bielekova, B.1
Howard, T.2
Packer, A.N.3
-
192
-
-
64949122507
-
Function of neurotrophic factors beyond the nervous system: Inflammation and autoimmune demyelination
-
Linker R., Gold R., Luhder F. Function of neurotrophic factors beyond the nervous system: inflammation and autoimmune demyelination. Crit Rev Immunol: 2009; 29 1 43 68
-
(2009)
Crit Rev Immunol
, vol.29
, Issue.1
, pp. 43-68
-
-
Linker, R.1
Gold, R.2
Luhder, F.3
|