메뉴 건너뛰기




Volumn 180, Issue 7, 2008, Pages 4409-4414

Lack of TIM-3 immunoregulation in multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CD3 ANTIBODY; GAMMA INTERFERON; GLATIRAMER; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY TIM 3; PROTEIN TIM 3; UNCLASSIFIED DRUG; HAVCR2 PROTEIN, HUMAN;

EID: 44449135110     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.7.4409     Document Type: Article
Times cited : (117)

References (31)
  • 2
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin in the central nervous system
    • Steinman, L. 1996. Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system. Cell 85: 299-302.
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 3
    • 0028990462 scopus 로고
    • Immunologic mechanisms and therapy in multiple sclerosis
    • Hafler, D. A., and H. L. Weiner. 1995. Immunologic mechanisms and therapy in multiple sclerosis. Immunol. Rev. 144: 75-107.
    • (1995) Immunol. Rev , vol.144 , pp. 75-107
    • Hafler, D.A.1    Weiner, H.L.2
  • 5
    • 0027845224 scopus 로고
    • Cytokine mRNA expression in inflammatory multiple sclerosis lesions: Detection by non-radioactive in situ hybridization
    • Woodroofe, M. N., and M. L. Cuzner. 1993. Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization. Cytokine 5: 583-588.
    • (1993) Cytokine , vol.5 , pp. 583-588
    • Woodroofe, M.N.1    Cuzner, M.L.2
  • 6
    • 0028809507 scopus 로고
    • Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
    • Windhagen, A., J. Newcombe, F. Dangond, C. Strand, M. N. Woodroofe, M. L. Cuzner, and D. A. Hafler. 1995. Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J. Exp. Med. 182: 1985-1996.
    • (1995) J. Exp. Med , vol.182 , pp. 1985-1996
    • Windhagen, A.1    Newcombe, J.2    Dangond, F.3    Strand, C.4    Woodroofe, M.N.5    Cuzner, M.L.6    Hafler, D.A.7
  • 7
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj, K., C. S. Raine, B. Cannella, and C. F. Brosnan. 1991. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J. Clin. Invest. 87: 949 -954.
    • (1991) J. Clin. Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 8
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman, F. M., D. R. Hinton, K. Johnson, and J. E. Merrill. 1989. Tumor necrosis factor identified in multiple sclerosis brain. J. Exp. Med. 170: 607-612.
    • (1989) J. Exp. Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 10
    • 0024357498 scopus 로고
    • Antiproliferative effect of IFN-γ in immune regulation: III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ
    • Gajewski, T. F., J. Joyce, and F. W. Fitch. 1989. Antiproliferative effect of IFN-γ in immune regulation: III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-γ. J. Immunol. 143: 15-22.
    • (1989) J. Immunol , vol.143 , pp. 15-22
    • Gajewski, T.F.1    Joyce, J.2    Fitch, F.W.3
  • 12
    • 12044249483 scopus 로고
    • IL-12: Initiation cytokine for cell-mediated immunity
    • Scott, P. 1993. IL-12: initiation cytokine for cell-mediated immunity. Science 260: 496 -497.
    • (1993) Science , vol.260 , pp. 496-497
    • Scott, P.1
  • 13
    • 0028288179 scopus 로고
    • Lymphokine production by human T cells in disease states
    • Romagnani, S. 1994. Lymphokine production by human T cells in disease states. Annu. Rev. Immunol. 12: 227-257.
    • (1994) Annu. Rev. Immunol , vol.12 , pp. 227-257
    • Romagnani, S.1
  • 14
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 16
    • 32244442562 scopus 로고    scopus 로고
    • TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen, M., R. J. Hocking, C. J. Atkins, R. M. Locksley, and B. Stockinger. 2006. TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179 -189.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 17
    • 33744936550 scopus 로고    scopus 로고
    • IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
    • Vaknin-Dembinsky, A., K. Balashov, and H. L. Weiner. 2006. IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J. Immunol. 176: 7768 -7774.
    • (2006) J. Immunol , vol.176 , pp. 7768-7774
    • Vaknin-Dembinsky, A.1    Balashov, K.2    Weiner, H.L.3
  • 18
    • 14744284737 scopus 로고    scopus 로고
    • IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human
    • Vanden Eijnden, S., S. Goriely, D. De Wit, F. Willems, and M. Goldman. 2005. IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human. Eur. J. Immunol. 35: 469 -475.
    • (2005) Eur. J. Immunol , vol.35 , pp. 469-475
    • Vanden Eijnden, S.1    Goriely, S.2    De Wit, D.3    Willems, F.4    Goldman, M.5
  • 25
    • 2442704124 scopus 로고    scopus 로고
    • T cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis
    • Khademi, M., Z. Illes, A. W. Gielen, M. Marta, N. Takazawa, C. Baecher-Allan, L. Brundin, J. Hannerz, C. Martin, R. A. Harris, et al. 2004. T cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis. J. Immunol. 172: 7169 -7176.
    • (2004) J. Immunol , vol.172 , pp. 7169-7176
    • Khademi, M.1    Illes, Z.2    Gielen, A.W.3    Marta, M.4    Takazawa, N.5    Baecher-Allan, C.6    Brundin, L.7    Hannerz, J.8    Martin, C.9    Harris, R.A.10
  • 27
    • 34247895422 scopus 로고    scopus 로고
    • Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
    • Nakae, S., Y. Iwakura, H. Suto, and S. J. Galli. 2007. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J. Leukocyte Biol. 81: 1258-1268.
    • (2007) J. Leukocyte Biol , vol.81 , pp. 1258-1268
    • Nakae, S.1    Iwakura, Y.2    Suto, H.3    Galli, S.J.4
  • 28
    • 33744980720 scopus 로고    scopus 로고
    • Prieto, A., D. Diaz, H. Barcenilla, C. Castrillo, J. Monserrat, A. G. Merino, and M. Alvarez-Mon. 2006. Increased spontaneous ex vivo apoptosis and subset alterations in peripheral blood T cells from patients with multiple sclerosis. J. Clin. Immunol. 26: 101-112.
    • Prieto, A., D. Diaz, H. Barcenilla, C. Castrillo, J. Monserrat, A. G. Merino, and M. Alvarez-Mon. 2006. Increased spontaneous ex vivo apoptosis and subset alterations in peripheral blood T cells from patients with multiple sclerosis. J. Clin. Immunol. 26: 101-112.
  • 31
    • 5644273987 scopus 로고    scopus 로고
    • What do we know about the mechanism of action of disease-modifying treatments in MS?
    • Hartung, H. P., A. Bar-Or, and Y. Zoukos. 2004. What do we know about the mechanism of action of disease-modifying treatments in MS? J. Neurol. 251(Suppl. 5): v12-v29.
    • (2004) J. Neurol , vol.251 , Issue.SUPPL. 5
    • Hartung, H.P.1    Bar-Or, A.2    Zoukos, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.