Unique clinical and pathological features in HLA-DRB1*0401-restricted MBP 111-129-specific humanized TCR transgenic mice

Journal of Experimental Medicine

Volumn 200, Issue 2, 2004, Pages 223-234

  Quandt, Jacqueline A ^a   Baig, Mirza ^a   Yao, Karen ^a   Kawamura, Kazuyuki ^a   Huh, Jaebong ^a   Ludwin, Samuel K ^c   Bian, Hong Jin ^d   Bryant, Mark ^b   Quigley, Laura ^a   Nagy, Zoltan A ^e   McFarland, Henry F ^a   Muraro, Paolo A ^a   Martin, Roland ^a   Ito, Kouichi ^a,f  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c QUEEN S UNIVERSITY   (Canada)

^d HOFFMANN LA ROCHE INC   (United States)

^e GPC Biotech AG   (Germany)

^f RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Experimental autoimmune encephalomyelitis; HLA DRB1*0401; Multiple sclerosis; Myelin basic protein; Transgenic mouse

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; GAMMA INTERFERON; HERMES ANTIGEN; HLA DR ANTIGEN; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; MYELIN BASIC PROTEIN; MYELIN BASIC PROTEIN[111-129]; PADGEM PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ALLELE; ALLERGIC ENCEPHALOMYELITIS; AMINO ACID ANALYSIS; ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; BRAIN STEM; CELL CLONE; CELL HETEROGENEITY; CELL INFILTRATION; CLINICAL FEATURE; CONTROLLED STUDY; CRANIAL NERVE; DEMYELINATION; DISEASE COURSE; DYSPHAGIA; EPITOPE MAPPING; GAIT DISORDER; HISTOPATHOLOGY; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPATHOGENESIS; INFLAMMATORY CELL; JAW MOVEMENT; MOUSE; NERVE ROOT; NEUROPATHOLOGY; NONHUMAN; PARALYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL NERVE; T LYMPHOCYTE RECEPTOR GENE; TONGUE; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; CELL SEPARATION; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FLOW CYTOMETRY; HLA-DR ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MULTIPLE SCLEROSIS; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL; TIME FACTORS;

EID: 3242800448     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20030994     Document Type: Article

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