The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis

Brain

Volumn 123, Issue 11, 2000, Pages 2256-2263

  Molyneux, P D ^a   Kappos, L ^a   Polman, C ^a   Pozzilli, C ^a   Barkhof, F ^a   Filippi, M ^a   Yousry, T ^a   Hahn, D ^a   Wagner, K ^a   Ghazi, M ^a   Beckmann, K ^a   Dahlke, F ^a   Losseff, N ^a   Barker, G J ^a   Thompson, A J ^a   Miller, D H ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cerebral atrophy; Interferon beta 1b; MRI; Multiple sclerosis; Secondary progressive multiple sclerosis

Indexed keywords

INTERFERON BETA SERINE;

ADULT; AGED; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; BRAIN SLICE; CONTRAST ENHANCEMENT; DIAGNOSTIC IMAGING; DRUG EFFECT; FEMALE; HEMISPHERE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOMES RESEARCH; PRIORITY JOURNAL; REPRODUCIBILITY;

ADULT; ATROPHY; CEREBRAL CORTEX; DISEASE PROGRESSION; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INTERFERON-BETA; MAGNETIC RESONANCE IMAGING; MALE; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RANDOMIZED CONTROLLED TRIALS; STATISTICAL DISTRIBUTIONS;

EID: 0033759398     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/123.11.2256     Document Type: Article

References (19)

1. Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis
2. Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis
3. Comparison of MS clinical phenotypes using conventional and magnetization transfer MRI
4. Progressive cerebral atrophy in MS. A serial study using registered, volumetric MRI
5. A reproducible repositioning method for serial magnetic resonance imaging studies of the brain in treatment trials for multiple sclerosis
6. Interferon beta-1b in the treatment of multiple sclerosis: Final outcome of the randomized, controlled trial
7. Progressive cerebral atrophy in multiple sclerosis. A serial MRI study
8. The role of magnetic resonance techniques in understanding and managing multiple sclerosis
9. Effect of interferon-beta 1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: Results of a European multicenter, randomized, double-blind, placebo-controlled trial
10. Correlations between monthly enhanced MRI lesion rate and changes in T2 lesion volume in multiple sclerosis
11. Quantitative MRI in patients with secondary progressive MS treated with monoclonal antibody Campath 1H
12. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial
13. Interferon beta-1b in secondary progressive multiple sclerosis-outline of the clinical trial
14. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
15. Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns, and prediction
16. The effect of Avonex on cerebral atrophy in relapsing multiple sclerosis
17. A longitudinal study of brain atrophy in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)
18. One year follow up study of primary and transitional progressive multiple sclerosis
19. A magnetization transfer histogram study of normal-appearing brain tissue in MS