Sodium chloride drives autoimmune disease by the induction of pathogenic TH 17 cells

Nature

Volumn 496, Issue 7446, 2013, Pages 518-522

  Kleinewietfeld, Markus ^a   Manzel, Arndt ^c,d   Titze, Jens ^c,e   Kvakan, Heda ^f,g   Yosef, Nir ^b   Linker, Ralf A ^c   Muller, Dominik N ^f,h   Hafler, David A ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

^e VANDERBILT UNIVERSITY   (United States)

^f MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^g HELIOS KLINIKUM BERLIN BUCH   (Germany)

^h UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; MITOGEN ACTIVATED PROTEIN KINASE P38; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SODIUM CHLORIDE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT5; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

CELL ORGANELLE; ENVIRONMENTAL FACTOR; GENETIC ANALYSIS; IMMUNE RESPONSE; IMMUNE SYSTEM; INHIBITION; NERVOUS SYSTEM; PATHOGENICITY; RODENT; SODIUM CHLORIDE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CELL MATURATION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; IN VIVO STUDY; MOUSE; NONHUMAN; PATHOGENICITY; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TH17 CELL; UPREGULATION;

ANIMALS; CELLS, CULTURED; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE SILENCING; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERLEUKIN-2; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; SODIUM CHLORIDE, DIETARY; TH17 CELLS; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MURINAE; MUS;

EID: 84876787121     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11868     Document Type: Article

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