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Volumn 189, Issue 7, 2012, Pages 3618-3630

TCR Bias and HLA cross-restriction are strategies of human brain-infiltrating JC virus-specific CD4+ T cells during viral infection

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA ANTIGEN CLASS 2; INTERLEUKIN 4; PROTEIN VP1; T LYMPHOCYTE RECEPTOR;

EID: 84866564112     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201612     Document Type: Article
Times cited : (29)

References (63)
  • 2
    • 0037432736 scopus 로고    scopus 로고
    • Immunology: CD8 T cells remember with a little help
    • DOI 10.1126/science.1084511
    • Kaech, S. M., and R. Ahmed. 2003. Immunology. CD8 T cells remember with a little help. Science 300: 263-265. (Pubitemid 36433703)
    • (2003) Science , vol.300 , Issue.5617 , pp. 263-265
    • Kaech, S.M.1    Ahmed, R.2
  • 3
    • 0027971622 scopus 로고
    • + cytotoxic T-cell responses during chronic viral infection
    • Matloubian, M., R. J. Concepcion, and R. Ahmed. 1994. CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection. J. Virol. 68: 8056-8063. (Pubitemid 24362694)
    • (1994) Journal of Virology , vol.68 , Issue.12 , pp. 8056-8063
    • Matloubian, M.1    Concepcion, R.J.2    Ahmed, R.3
  • 4
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • DOI 10.1126/science.1082305
    • Shedlock, D. J., and H. Shen. 2003. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300: 337-339. (Pubitemid 36433726)
    • (2003) Science , vol.300 , Issue.5617 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 5
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • DOI 10.1126/science.1083317
    • Sun, J. C., and M. J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300: 339-342. (Pubitemid 36433727)
    • (2003) Science , vol.300 , Issue.5617 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 6
    • 0030053663 scopus 로고    scopus 로고
    • CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge
    • von Herrath, M. G., M. Yokoyama, J. Dockter, M. B. Oldstone, and J. L. Whitton. 1996. CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge. J. Virol. 70: 1072-1079. (Pubitemid 26029026)
    • (1996) Journal of Virology , vol.70 , Issue.2 , pp. 1072-1079
    • Von Herrath, M.G.1    Yokoyama, M.2    Dockter, J.3    Oldstone, M.B.A.4    Lindsay, W.J.5
  • 8
    • 0030986358 scopus 로고    scopus 로고
    • A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers
    • Planz, O., S. Ehl, E. Furrer, E. Horvath, M. A. Bründler, H. Hengartner, and R. M. Zinkernagel. 1997. A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proc. Natl. Acad. Sci. USA 94: 6874-6879.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6874-6879
    • Planz, O.1    Ehl, S.2    Furrer, E.3    Horvath, E.4    Bründler, M.A.5    Hengartner, H.6    Zinkernagel, R.M.7
  • 11
  • 12
    • 0041867853 scopus 로고    scopus 로고
    • Critical role of JC virus-specific CD4 T-cell responses in preventing progressive multifocal leukoencephalopathy
    • DOI 10.1097/00002030-200307040-00004
    • Gasnault, J., M. Kahraman, M. G. de Goër de Herve, D. Durali, J. F. Delfraissy, and Y. Taoufik. 2003. Critical role of JC virus-specific CD4 T-cell responses in preventing progressive multifocal leukoencephalopathy. AIDS 17: 1443-1449. (Pubitemid 36900544)
    • (2003) AIDS , vol.17 , Issue.10 , pp. 1443-1449
    • Gasnault, J.1    Kahraman, M.2    De Herve, M.G.D.G.3    Durali, D.4    Delfraissy, J.-F.5    Taoufik, Y.6
  • 13
    • 77949375380 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy in patients on immunomodulatory therapies
    • Major, E. O. 2010. Progressive multifocal leukoencephalopathy in patients on immunomodulatory therapies. Annu. Rev. Med. 61: 35-47.
    • (2010) Annu. Rev. Med. , vol.61 , pp. 35-47
    • Major, E.O.1
  • 14
    • 77649139783 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy in individuals with minimal or occult immunosuppression
    • Gheuens, S., G. Pierone, P. Peeters, and I. J. Koralnik. 2010. Progressive multifocal leukoencephalopathy in individuals with minimal or occult immunosuppression. J. Neurol. Neurosurg. Psychiatry 81: 247-254.
    • (2010) J. Neurol. Neurosurg. Psychiatry , vol.81 , pp. 247-254
    • Gheuens, S.1    Pierone, G.2    Peeters, P.3    Koralnik, I.J.4
  • 15
    • 77949619394 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy in a patient with idiopathic CD4+T lymphocytopenia
    • Puri, V., N. Chaudhry, P. Gulati, N. Patel, M. Tatke, and S. Sinha. 2010. Progressive multifocal leukoencephalopathy in a patient with idiopathic CD4+T lymphocytopenia. Neurol. India 58: 118-121.
    • (2010) Neurol. India , vol.58 , pp. 118-121
    • Puri, V.1    Chaudhry, N.2    Gulati, P.3    Patel, N.4    Tatke, M.5    Sinha, S.6
  • 16
    • 77949297173 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: Clinical features and pathogenesis
    • Tan, C. S., and I. J. Koralnik. 2010. Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis. Lancet Neurol. 9: 425-437.
    • (2010) Lancet Neurol. , vol.9 , pp. 425-437
    • Tan, C.S.1    Koralnik, I.J.2
  • 17
    • 0015232447 scopus 로고
    • Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy
    • Padgett, B. L., D. L. Walker, G. M. ZuRhein, R. J. Eckroade, and B. H. Dessel. 1971. Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1: 1257-1260.
    • (1971) Lancet , vol.1 , pp. 1257-1260
    • Padgett, B.L.1    Walker, D.L.2    ZuRhein, G.M.3    Eckroade, R.J.4    Dessel, B.H.5
  • 18
    • 0036136313 scopus 로고    scopus 로고
    • + progressive multifocal leukoencephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope
    • Koralnik, I. J., R. A. Du Pasquier, M. J. Kuroda, J. E. Schmitz, X. Dang, Y. Zheng, M. Lifton, and N. L. Letvin. 2002. Association of prolonged survival in HLA-A2+ progressive multifocal leukoencephalopathy patients with a CTL response specific for a commonly recognized JC virus epitope. J. Immunol. 168: 499-504. (Pubitemid 34014154)
    • (2002) Journal of Immunology , vol.168 , Issue.1 , pp. 499-504
    • Koralnik, I.J.1    Du, P.R.A.2    Kuroda, M.J.3    Schmitz, J.E.4    Dang, X.5    Zheng, Y.6    Lifton, M.7    Letvin, N.L.8
  • 19
    • 4344600302 scopus 로고    scopus 로고
    • A prospective study demonstrates an association between JC virus-specific cytotoxic T lymphocytes and the early control of progressive multifocal leukoencephalopathy
    • DOI 10.1093/brain/awh215
    • Du Pasquier, R. A., M. J. Kuroda, Y. Zheng, J. Jean-Jacques, N. L. Letvin, and I. J. Koralnik. 2004. A prospective study demonstrates an association between JC virus-specific cytotoxic T lymphocytes and the early control of progressive multifocal leukoencephalopathy. Brain 127: 1970-1978. (Pubitemid 39150256)
    • (2004) Brain , vol.127 , Issue.9 , pp. 1970-1978
    • Du, P.R.A.1    Kuroda, M.J.2    Zheng, Y.3    Jean-Jacques, J.4    Letvin, N.L.5    Koralnik, I.J.6
  • 21
    • 79960418196 scopus 로고    scopus 로고
    • Role of CD4+ and CD8+ T-cell responses against JC virus in the outcome of patients with progressive multifocal leukoencephalopathy (PML) and PML with immune reconstitution inflammatory syndrome
    • Gheuens, S., E. Bord, S. Kesari, D. M. Simpson, R. T. Gandhi, D. B. Clifford, J. R. Berger, L. Ngo, and I. J. Koralnik. 2011. Role of CD4+ and CD8+ T-cell responses against JC virus in the outcome of patients with progressive multifocal leukoencephalopathy (PML) and PML with immune reconstitution inflammatory syndrome. J. Virol. 85: 7256-7263.
    • (2011) J. Virol. , vol.85 , pp. 7256-7263
    • Gheuens, S.1    Bord, E.2    Kesari, S.3    Simpson, D.M.4    Gandhi, R.T.5    Clifford, D.B.6    Berger, J.R.7    Ngo, L.8    Koralnik, I.J.9
  • 23
    • 0036956426 scopus 로고    scopus 로고
    • Overview of the cellular immunity against JC virus in progressive multifocal leukoencephalopathy
    • DOI 10.1080/13550280290167894
    • Koralnik, I. J. 2002. Overview of the cellular immunity against JC virus in progressive multifocal leukoencephalopathy. J. Neurovirol. 8(Suppl 2): 59-65. (Pubitemid 36097778)
    • (2002) Journal of NeuroVirology , vol.8 , Issue.SUPPL. 2 , pp. 59-65
    • Koralnik, I.J.1
  • 25
    • 0005861795 scopus 로고
    • JC papovavirus large tumor (T)-antigen expression in brain tissue of acquired immune deficiency syndrome (AIDS) and non-AIDS patients with progressive multifocal leukoencephalopathy
    • Stoner, G. L., C. F. Ryschkewitsch, D. L. Walker, and H. D. Webster. 1986. JC papovavirus large tumor (T)-antigen expression in brain tissue of acquired immune deficiency syndrome (AIDS) and non-AIDS patients with progressive multifocal leukoencephalopathy. Proc. Natl. Acad. Sci. USA 83: 2271-2275.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2271-2275
    • Stoner, G.L.1    Ryschkewitsch, C.F.2    Walker, D.L.3    Webster, H.D.4
  • 27
    • 22844439662 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis
    • DOI 10.1056/NEJMoa051782
    • Kleinschmidt-DeMasters, B. K., and K. L. Tyler. 2005. Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis. N. Engl. J. Med. 353: 369-374. (Pubitemid 41132341)
    • (2005) New England Journal of Medicine , vol.353 , Issue.4 , pp. 369-374
    • Kleinschmidt-DeMasters, B.K.1    Tyler, K.L.2
  • 28
    • 22844445230 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy in a patient treated with natalizumab
    • DOI 10.1056/NEJMoa051847
    • Langer-Gould, A., S. W. Atlas, A. J. Green, A. W. Bollen, and D. Pelletier. 2005. Progressive multifocal leukoencephalopathy in a patient treated with natalizumab. N. Engl. J. Med. 353: 375-381. (Pubitemid 41132342)
    • (2005) New England Journal of Medicine , vol.353 , Issue.4 , pp. 375-381
    • Langer-Gould, A.1    Atlas, S.W.2    Green, A.J.3    Bollen, A.W.4    Pelletier, D.5
  • 30
    • 77949297173 scopus 로고    scopus 로고
    • Comment to: Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis: C. D. Tan, I. J. Koralnik
    • 2010
    • Urbach, H. 2010. Comment to: progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis: C. D. Tan, I. J. Koralnik Lancet Neurol. 2010;9:425-37.
    • (2010) Lancet Neurol. , vol.9 , pp. 425-437
    • Urbach, H.1
  • 34
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin
    • Yednock, T. A., C. Cannon, L. C. Fritz, F. Sanchez-Madrid, L. Steinman, and N. Karin. 1992. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature 356: 63-66.
    • (1992) Nature , vol.356 , pp. 63-66
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 35
    • 33746825429 scopus 로고    scopus 로고
    • Progressive multifocal leukoencephalopathy revisited: Has the disease outgrown its name?
    • DOI 10.1002/ana.20933
    • Koralnik, I. J. 2006. Progressive multifocal leukoencephalopathy revisited: Has the disease outgrown its name? Ann. Neurol. 60: 162-173. (Pubitemid 44182391)
    • (2006) Annals of Neurology , vol.60 , Issue.2 , pp. 162-173
    • Koralnik, I.J.1
  • 36
    • 67549085134 scopus 로고    scopus 로고
    • PML-IRIS in patients with HIV infection: Clinical manifestations and treatment with steroids
    • Tan, K., R. Roda, L. Ostrow, J. McArthur, and A. Nath. 2009. PML-IRIS in patients with HIV infection: clinical manifestations and treatment with steroids. Neurology 72: 1458-1464.
    • (2009) Neurology , vol.72 , pp. 1458-1464
    • Tan, K.1    Roda, R.2    Ostrow, L.3    McArthur, J.4    Nath, A.5
  • 37
    • 80052942855 scopus 로고    scopus 로고
    • Central role of JC virus-specific CD4+ lymphocytes in progressive multi-focal leucoencephalopathy-immune reconstitution inflammatory syndrome
    • Aly, L., S. Yousef, S. Schippling, I. Jelcic, P. Breiden, J. Matschke, R. Schulz, S. Bofill-Mas, L. Jones, V. Demina, et al. 2011. Central role of JC virus-specific CD4+ lymphocytes in progressive multi-focal leucoencephalopathy- immune reconstitution inflammatory syndrome. Brain 134: 2687-2702.
    • (2011) Brain , vol.134 , pp. 2687-2702
    • Aly, L.1    Yousef, S.2    Schippling, S.3    Jelcic, I.4    Breiden, P.5    Matschke, J.6    Schulz, R.7    Bofill-Mas, S.8    Jones, L.9    Demina, V.10
  • 38
    • 33845190339 scopus 로고    scopus 로고
    • Structural determinants of T-cell receptor bias in immunity
    • DOI 10.1038/nri1977, PII NRI1977
    • Turner, S. J., P. C. Doherty, J. McCluskey, and J. Rossjohn. 2006. Structural determinants of T-cell receptor bias in immunity. Nat. Rev. Immunol. 6: 883-894. (Pubitemid 44851731)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.12 , pp. 883-894
    • Turner, S.J.1    Doherty, P.C.2    McCluskey, J.3    Rossjohn, J.4
  • 39
    • 79952816254 scopus 로고    scopus 로고
    • Bias in the αβ T-cell repertoire: Implications for disease pathogenesis and vaccination
    • Miles, J. J., D. C. Douek, and D. A. Price. 2011. Bias in the αβ T-cell repertoire: implications for disease pathogenesis and vaccination. Immunol. Cell Biol. 89: 375-387.
    • (2011) Immunol. Cell Biol. , vol.89 , pp. 375-387
    • Miles, J.J.1    Douek, D.C.2    Price, D.A.3
  • 40
    • 0025992233 scopus 로고
    • Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide
    • Moss, P. A., R. J. Moots, W. M. Rosenberg, S. J. Rowland-Jones, H. C. Bodmer, A. J. McMichael, and J. I. Bell. 1991. Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide. Proc. Natl. Acad. Sci. USA 88: 8987-8990.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8987-8990
    • Moss, P.A.1    Moots, R.J.2    Rosenberg, W.M.3    Rowland-Jones, S.J.4    Bodmer, H.C.5    McMichael, A.J.6    Bell, J.I.7
  • 41
    • 0028909051 scopus 로고
    • Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment
    • Lehner, P. J., E. C. Wang, P. A. Moss, S. Williams, K. Platt, S. M. Friedman, J. I. Bell, and L. K. Borysiewicz. 1995. Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment. J. Exp. Med. 181: 79-91.
    • (1995) J. Exp. Med. , vol.181 , pp. 79-91
    • Lehner, P.J.1    Wang, E.C.2    Moss, P.A.3    Williams, S.4    Platt, K.5    Friedman, S.M.6    Bell, J.I.7    Borysiewicz, L.K.8
  • 46
    • 0031842156 scopus 로고    scopus 로고
    • A dominant Vβ bias in the CTL response after HSV-1 infection is determined by peptide residues predicted to also interact with the TCR β- chain CDR3
    • DOI 10.1016/S0161-5890(98)00051-0, PII S0161589098000510
    • Turner, S. J., and F. R. Carbone. 1998. A dominant V beta bias in the CTL response after HSV-1 infection is determined by peptide residues predicted to also interact with the TCR beta-chain CDR3. Mol. Immunol. 35: 307-316. (Pubitemid 28389691)
    • (1998) Molecular Immunology , vol.35 , Issue.5 , pp. 307-316
    • Turner, S.J.1    Carbone, F.R.2
  • 48
    • 38949100462 scopus 로고    scopus 로고
    • The Structural Dynamics and Energetics of an Immunodominant T Cell Receptor Are Programmed by Its Vβ Domain
    • DOI 10.1016/j.immuni.2007.12.018, PII S1074761308000411
    • Ishizuka, J., G. B. Stewart-Jones, A. van der Merwe, J. I. Bell, A. J. McMichael, and E. Y. Jones. 2008. The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain. Immunity 28: 171-182. (Pubitemid 351215238)
    • (2008) Immunity , vol.28 , Issue.2 , pp. 171-182
    • Ishizuka, J.1    Stewart-Jones, G.B.E.2    Van Der Merwe, A.3    Bell, J.I.4    McMichael, A.J.5    Jones, E.Y.6
  • 49
    • 0028927653 scopus 로고
    • Antigen-specific development of primary and memory T cells in vivo
    • McHeyzer-Williams, M. G., and M. M. Davis. 1995. Antigen-specific development of primary and memory T cells in vivo. Science 268: 106-111.
    • (1995) Science , vol.268 , pp. 106-111
    • McHeyzer-Williams, M.G.1    Davis, M.M.2
  • 50
    • 0033532540 scopus 로고    scopus 로고
    • Evolution of antigen-specific T cell receptors in vivo: Preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs
    • McHeyzer-Williams, L. J., J. F. Panus, J. A. Mikszta, and M. G. McHeyzer-Williams. 1999. Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs. J. Exp. Med. 189: 1823-1838.
    • (1999) J. Exp. Med. , vol.189 , pp. 1823-1838
    • McHeyzer-Williams, L.J.1    Panus, J.F.2    Mikszta, J.A.3    McHeyzer-Williams, M.G.4
  • 52
    • 0042166065 scopus 로고    scopus 로고
    • + T clones specific for an immunodominant epitope of Mycobacterium tuberculosis 16-kDa protein
    • DOI 10.1046/j.1365-2249.2003.02201.x
    • Caccamo, N., A. Barera, C. Di Sano, S. Meraviglia, J. Ivanyi, F. Hudecz, S. Bosze, F. Dieli, and A. Salerno. 2003. Cytokine profile, HLA restriction and TCR sequence analysis of human CD4+ T clones specific for an immunodominant epitope of Mycobacterium tuberculosis 16-kDa protein. Clin. Exp. Immunol. 133: 260-266. (Pubitemid 36918601)
    • (2003) Clinical and Experimental Immunology , vol.133 , Issue.2 , pp. 260-266
    • Caccamo, N.1    Barera, A.2    Di, S.C.3    Meraviglia, S.4    Ivanyi, J.5    Hudecz, F.6    Bosze, S.7    Dieli, F.8    Salerno, A.9
  • 56
    • 0032194159 scopus 로고    scopus 로고
    • Structural basis of specificity and degeneracy of T cell recognition: Pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR
    • Doherty, D. G., J. E. Penzotti, D. M. Koelle, W. W. Kwok, T. P. Lybrand, S. Masewicz, and G. T. Nepom. 1998. Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR. J. Immunol. 161: 3527-3535.
    • (1998) J. Immunol. , vol.161 , pp. 3527-3535
    • Doherty, D.G.1    Penzotti, J.E.2    Koelle, D.M.3    Kwok, W.W.4    Lybrand, T.P.5    Masewicz, S.6    Nepom, G.T.7
  • 57
    • 0037018102 scopus 로고    scopus 로고
    • Structure of a complex of the human α/β T cell receptor (TCR) HA1.7, Influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRBI*0401): Insight into TCR cross-restriction and alloreactivity
    • DOI 10.1084/jem.20011194
    • Hennecke, J., and D. C. Wiley. 2002. Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivity. J. Exp. Med. 195: 571-581. (Pubitemid 34461502)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.5 , pp. 571-581
    • Hennecke, J.1    Wiley, D.C.2
  • 58
    • 0042470456 scopus 로고    scopus 로고
    • Positive and negative selection of T cells
    • DOI 10.1146/annurev.immunol.21.120601.141107
    • Starr, T. K., S. C. Jameson, and K. A. Hogquist. 2003. Positive and negative selection of T cells. Annu. Rev. Immunol. 21: 139-176. (Pubitemid 37174529)
    • (2003) Annual Review of Immunology , vol.21 , pp. 139-176
    • Starr, T.K.1    Jameson, S.C.2    Hogquist, K.A.3
  • 60
    • 0030176009 scopus 로고    scopus 로고
    • Mitogens, superantigens, and nominal antigens elicit distinctive patterns of TCRB CDR3 diversity
    • DOI 10.1016/0198-8859(96)00076-6
    • Currier, J. R., H. Deulofeut, K. S. Barron, P. J. Kehn, and M. A. Robinson. 1996. Mitogens, superantigens, and nominal antigens elicit distinctive patterns of TCRB CDR3 diversity. Hum. Immunol. 48: 39-51. (Pubitemid 26238952)
    • (1996) Human Immunology , vol.48 , Issue.1-2 , pp. 39-51
    • Currier, J.R.1    Deulofreut, H.2    Barron, K.S.3    Kehn, P.J.4    Robinson, M.A.5
  • 61
    • 0028169415 scopus 로고
    • Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice
    • Cibotti, R., J.-P. Cabaniols, C. Pannetier, C. Delarbre, I. Vergnon, J. M. Kanellopoulos, and P. Kourilsky. 1994. Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice. J. Exp. Med. 180: 861-872.
    • (1994) J. Exp. Med. , vol.180 , pp. 861-872
    • Cibotti, R.1    Cabaniols, J.-P.2    Pannetier, C.3    Delarbre, C.4    Vergnon, I.5    Kanellopoulos, J.M.6    Kourilsky, P.7
  • 62
    • 0242331748 scopus 로고    scopus 로고
    • p36 in Patients with Proven or Possible Progressive Multifocal Leukoencephalopathy
    • DOI 10.1128/JVI.77.22.11918-11926.2003
    • Du Pasquier, R. A., M. J. Kuroda, J. E. Schmitz, Y. Zheng, K. Martin, F. W. Peyerl, M. Lifton, D. Gorgone, P. Autissier, N. L. Letvin, and I. J. Koralnik. 2003. Low frequency of cytotoxic T lymphocytes against the novel HLA-A*0201-restricted JC virus epitope VP1(p36) in patients with proven or possible progressive multifocal leukoencephalopathy. J. Virol. 77: 11918-11926. (Pubitemid 37339845)
    • (2003) Journal of Virology , vol.77 , Issue.22 , pp. 11918-11926
    • Du, P.R.A.1    Kuroda, M.J.2    Schmitz, J.E.3    Zheng, Y.4    Martin, K.5    Peyerl, F.W.6    Lifton, M.7    Gorgone, D.8    Autissier, P.9    Letvin, N.L.10    Koralnik, I.J.11


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