메뉴 건너뛰기




Volumn 47, Issue 6, 2000, Pages 707-717

Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL FEATURE; DEMYELINATING DISEASE; DISEASE ACTIVITY; DISEASE COURSE; HUMAN; HUMAN TISSUE; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0342906187     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(200006)47:6<707::AID-ANA3>3.0.CO;2-Q     Document Type: Article
Times cited : (2815)

References (45)
  • 1
    • 15844366743 scopus 로고    scopus 로고
    • A full genomic search in multiple sclerosis
    • Ebers GC, Kukay K, Bulman DE, et al. A full genomic search in multiple sclerosis. Nat Genet 1996;13:472-476
    • (1996) Nat Genet , vol.13 , pp. 472-476
    • Ebers, G.C.1    Kukay, K.2    Bulman, D.E.3
  • 2
    • 0009573338 scopus 로고    scopus 로고
    • A genomic screen for multiple sclerosis underscores a role for the major histocompatibility complex
    • Haines JL, Ter-Minassian M, Bazyk A, et al. A genomic screen for multiple sclerosis underscores a role for the major histocompatibility complex. The Multiple Sclerosis Genetics Group. Nat Gen 1996;13:469-471
    • (1996) The Multiple Sclerosis Genetics Group. Nat Gen , vol.13 , pp. 469-471
    • Haines, J.L.1    Ter-Minassian, M.2    Bazyk, A.3
  • 3
    • 15844368830 scopus 로고    scopus 로고
    • A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22
    • Sawcer S, Jones HB, Feakes R, et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 1996;13:469-471
    • (1996) Nat Genet , vol.13 , pp. 469-471
    • Sawcer, S.1    Jones, H.B.2    Feakes, R.3
  • 4
    • 0000386858 scopus 로고    scopus 로고
    • Natural history of multiple sclerosis
    • Compston A, ed. London: Churchill Livingstone
    • Ebers G. Natural history of multiple sclerosis. In: Compston A, ed. McAlpine's multiple sclerosis. 3rd ed. London: Churchill Livingstone, 1998:191-222
    • (1998) McAlpine's Multiple Sclerosis. 3rd Ed. , pp. 191-222
    • Ebers, G.1
  • 5
    • 0000268469 scopus 로고    scopus 로고
    • Genetic susceptibility to multiple sclerosis
    • Compston A, ed. London: Churchill Livingsrone
    • Compston A. Genetic susceptibility to multiple sclerosis. In: Compston A, ed. McAlpine's multiple sclerosis. 3rd ed. London: Churchill Livingsrone, 1998:101-142
    • (1998) McAlpine's Multiple Sclerosis. 3rd Ed. , pp. 101-142
    • Compston, A.1
  • 6
    • 0032764919 scopus 로고    scopus 로고
    • Spatial mapping of T2 and gadolinium-enhancing T1 lesion volumes in MS: Evidence for distinct mechanisms of lesion genesis?
    • Lee MA, Smith S, Palace J, et al. Spatial mapping of T2 and gadolinium-enhancing T1 lesion volumes in MS: evidence for distinct mechanisms of lesion genesis? Brain 1999;122:1261-1270
    • (1999) Brain , vol.122 , pp. 1261-1270
    • Lee, M.A.1    Smith, S.2    Palace, J.3
  • 7
    • 0028082170 scopus 로고
    • Reactive microglia in multiple sclerosis lesions have an increased expression of receptors for the Fc part of IgG
    • Ulvestad E, Williams K, Vedeler C, et al. Reactive microglia in multiple sclerosis lesions have an increased expression of receptors for the Fc part of IgG. J Neurol Sci 1994;121:125-131
    • (1994) J Neurol Sci , vol.121 , pp. 125-131
    • Ulvestad, E.1    Williams, K.2    Vedeler, C.3
  • 8
    • 0031019547 scopus 로고    scopus 로고
    • Indictment of microglia as the villain in multiple sclerosis
    • Sriram S, Rodriguez M. Indictment of microglia as the villain in multiple sclerosis. Neurology 1997;48:464-470
    • (1997) Neurology , vol.48 , pp. 464-470
    • Sriram, S.1    Rodriguez, M.2
  • 9
    • 0028843731 scopus 로고
    • Monocyte/macrophage differentiation in early multiple sclerosis lesions
    • Brück W, Porada P, Poser S, et al. Monocyte/macrophage differentiation in early multiple sclerosis lesions. Ann Neurol 1995;38:788-796
    • (1995) Ann Neurol , vol.38 , pp. 788-796
    • Brück, W.1    Porada, P.2    Poser, S.3
  • 10
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman FM, Hinton DR, Johnson K, Merrill JE. Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 1989;170:607-612
    • (1989) J Exp Med , vol.170 , pp. 607-612
    • Hofman, F.M.1    Hinton, D.R.2    Johnson, K.3    Merrill, J.E.4
  • 11
    • 0025852567 scopus 로고
    • Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
    • Selmaj K, Raine CS, Cannella B, Brosnan CF. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 1991;87:949-954
    • (1991) J Clin Invest , vol.87 , pp. 949-954
    • Selmaj, K.1    Raine, C.S.2    Cannella, B.3    Brosnan, C.F.4
  • 12
    • 0029939467 scopus 로고    scopus 로고
    • Multiple sclerosis: A coordinated immunological attack against myelin of the central nervous system
    • Steinman L. Multiple sclerosis: a coordinated immunological attack against myelin of the central nervous system. Cell 1996; 85:299-302
    • (1996) Cell , vol.85 , pp. 299-302
    • Steinman, L.1
  • 13
    • 0029592005 scopus 로고
    • Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis
    • Bagasra O, Michaels FH, Zheng YM, et al. Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis. Proc Natl Acad Sci USA 1995;92: 12041-12045
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12041-12045
    • Bagasra, O.1    Michaels, F.H.2    Zheng, Y.M.3
  • 14
    • 0019469331 scopus 로고
    • Multiple sclerosis: Capping of surface immunoglobulin G on macrophages engaged in myelin breakdown
    • Prineas JW, Graham JS. Multiple sclerosis: capping of surface immunoglobulin G on macrophages engaged in myelin breakdown. Ann Neurol 1981;10:149-158
    • (1981) Ann Neurol , vol.10 , pp. 149-158
    • Prineas, J.W.1    Graham, J.S.2
  • 15
    • 0031748566 scopus 로고    scopus 로고
    • Multiple sclerosis: In situ evidence for antibody and complement mediated demyelination
    • Storch MK, Piddlesden S, Haltia M, et al. Multiple sclerosis: in situ evidence for antibody and complement mediated demyelination. Ann Neurol 1998a;43:465-471
    • (1998) Ann Neurol , vol.43 , pp. 465-471
    • Storch, M.K.1    Piddlesden, S.2    Haltia, M.3
  • 16
    • 1842367972 scopus 로고    scopus 로고
    • The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis: Identification and characterization of primary demyelinating lesion
    • Gay FW, Drye TJ, Dick GW, Esiri MM. The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis: identification and characterization of primary demyelinating lesion. Brain 1997;120:1461-1483
    • (1997) Brain , vol.120 , pp. 1461-1483
    • Gay, F.W.1    Drye, T.J.2    Dick, G.W.3    Esiri, M.M.4
  • 18
    • 0018844966 scopus 로고
    • Immunocytochemical observations on the distribution of myelin-associated glycoprotein and myelin basic protein in multiple sclerosis lesions
    • Itoyama Y, Sternberger NH, Webster H deF, et al. Immunocytochemical observations on the distribution of myelin-associated glycoprotein and myelin basic protein in multiple sclerosis lesions. Ann Neurol 1980;7:167-177.
    • (1980) Ann Neurol , vol.7 , pp. 167-177
    • Itoyama, Y.1    Sternberger, N.H.2    Webster, H.D.F.3
  • 20
    • 0028578038 scopus 로고
    • Patterns of oligodendroglia pathology in multiple sclerosis
    • Ozawa K, Suchanek G, Breitschopf H, et al. Patterns of oligodendroglia pathology in multiple sclerosis. Brain 1994;117: 1311-1322
    • (1994) Brain , vol.117 , pp. 1311-1322
    • Ozawa, K.1    Suchanek, G.2    Breitschopf, H.3
  • 21
    • 0030056764 scopus 로고    scopus 로고
    • Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis
    • Lucchinetti CL, Bruck WB, Rodriguez M, Lassmann H. Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis. Brain Pathology 1996;6:259-274
    • (1996) Brain Pathology , vol.6 , pp. 259-274
    • Lucchinetti, C.L.1    Bruck, W.B.2    Rodriguez, M.3    Lassmann, H.4
  • 22
    • 0022553992 scopus 로고
    • The distribution of Ia-antigen in the lesions of rat acute experimental allergic encephalomyelitis
    • Vass K, Lassmann H, Wekerle H, Wisniewski HM. The distribution of Ia-antigen in the lesions of rat acute experimental allergic encephalomyelitis. Acta Neuropathol (Berl) 1986;70: 149-160
    • (1986) Acta Neuropathol (Berl) , vol.70 , pp. 149-160
    • Vass, K.1    Lassmann, H.2    Wekerle, H.3    Wisniewski, H.M.4
  • 23
    • 0026468291 scopus 로고
    • In situ hybridization with digoxigenin-labeled probes: Sensitive and reliable detection method applied to myelinating rat brain
    • Breitschopf H, Suchanek G, Gould RM, et al. In situ hybridization with digoxigenin-labeled probes: sensitive and reliable detection method applied to myelinating rat brain. Acta Neuropathol 1992;84:581-587
    • (1992) Acta Neuropathol , vol.84 , pp. 581-587
    • Breitschopf, H.1    Suchanek, G.2    Gould, R.M.3
  • 24
    • 0028136653 scopus 로고
    • Differentiation between cellular apoptosis and necrosis by combined use of in situ tailing and nick translation techniques
    • Gold R, Schmied M, Giegerich G, et al. Differentiation between cellular apoptosis and necrosis by combined use of in situ tailing and nick translation techniques. Lab Invest 1994;71: 219-225
    • (1994) Lab Invest , vol.71 , pp. 219-225
    • Gold, R.1    Schmied, M.2    Giegerich, G.3
  • 25
    • 0000138505 scopus 로고
    • Detail zur grauen degeneration von gehirn und rückenmark
    • Rindfleisch E. Histologisches Detail zur grauen Degeneration von Gehirn und Rückenmark. Arch Pathol Anat Physiol Klin Med (Virchow) 1863;26:474-483
    • (1863) Arch Pathol Anat Physiol Klin Med (Virchow) , vol.26 , pp. 474-483
    • Rindfleisch, E.1
  • 26
    • 84974201150 scopus 로고
    • The histology of disseminated sclerosis
    • Dawson JW. The histology of disseminated sclerosis. Trans R Soc 1916;50:517-540
    • (1916) Trans R Soc , vol.50 , pp. 517-540
    • Dawson, J.W.1
  • 27
    • 0030738366 scopus 로고    scopus 로고
    • Multiple sclerosis: Oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
    • Bonetti B, Raine CS. Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis. Ann Neurol 1997;42:74-84
    • (1997) Ann Neurol , vol.42 , pp. 74-84
    • Bonetti, B.1    Raine, C.S.2
  • 28
    • 0023931606 scopus 로고
    • Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/ oligodendrocyte glycoprotein
    • Linington C, Bradl M, Lassmann H, et al. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/ oligodendrocyte glycoprotein. Am J Pathol 1988;130:443-454
    • (1988) Am J Pathol , vol.130 , pp. 443-454
    • Linington, C.1    Bradl, M.2    Lassmann, H.3
  • 29
    • 0031688565 scopus 로고    scopus 로고
    • Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology
    • Storch MK, Stefferl A, Brehm U, et al. Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology. Brain Pathol 1998b;8:681-694
    • (1998) Brain Pathol , vol.8 , pp. 681-694
    • Storch, M.K.1    Stefferl, A.2    Brehm, U.3
  • 30
    • 0031960227 scopus 로고    scopus 로고
    • Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible ro experimental autoimmune encephalomyelitis
    • Sahrbacher UC, Lechner F, Eugster HP, et al. Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible ro experimental autoimmune encephalomyelitis. Eur J Immunol 1998;28:1332-1338
    • (1998) Eur J Immunol , vol.28 , pp. 1332-1338
    • Sahrbacher, U.C.1    Lechner, F.2    Eugster, H.P.3
  • 31
    • 0020039451 scopus 로고
    • Distribution of papovavirus, myelin-associated glycoprotein, and myelin basic protein in progressive multifocal leukoencephalopathy lesions
    • Itoyama Y, Webster H deF, Sternberger NH, et al. Distribution of papovavirus, myelin-associated glycoprotein, and myelin basic protein in progressive multifocal leukoencephalopathy lesions. Ann Neurol 1982;11:396-407
    • (1982) Ann Neurol , vol.11 , pp. 396-407
    • Itoyama, Y.1    Webster, H.D.F.2    Sternberger, N.H.3
  • 32
    • 0020442111 scopus 로고
    • Immunocytochemical study of myelin-associated glycoprotein and basic protein in acute experimental allergic encephalomyelitis (EAE)
    • Itoyama Y, H deF Webster. Immunocytochemical study of myelin-associated glycoprotein and basic protein in acute experimental allergic encephalomyelitis (EAE). J Neuroimmunol 1982;3:351-364
    • (1982) J Neuroimmunol , vol.3 , pp. 351-364
    • Itoyama, Y.1    Webster, H.D.F.2
  • 33
    • 0020076467 scopus 로고
    • Myelin-associated glycoprotein localized immunocytochemically in peroaxonal regions of oligodendroglia during hexachlorophene intoxication
    • Winchell KH, Sternberger NH, Webster H deF. Myelin-associated glycoprotein localized immunocytochemically in peroaxonal regions of oligodendroglia during hexachlorophene intoxication. Brain Res 1982;239:679-684
    • (1982) Brain Res , vol.239 , pp. 679-684
    • Winchell, K.H.1    Sternberger, N.H.2    Webster, H.D.F.3
  • 34
    • 0021268108 scopus 로고
    • Immunocytochemical localization of the myelin-associated glycoprotein
    • Trapp BD, Quarles RH. Immunocytochemical localization of the myelin-associated glycoprotein. J Neuroimmunol 1984;6: 231-249
    • (1984) J Neuroimmunol , vol.6 , pp. 231-249
    • Trapp, B.D.1    Quarles, R.H.2
  • 35
    • 0025651203 scopus 로고
    • Myelin-associated glycoprotein: Location and potential functions
    • Trapp BD. Myelin-associated glycoprotein: location and potential functions. Ann NY Acad Sci 1990;605:29-43
    • (1990) Ann NY Acad Sci , vol.605 , pp. 29-43
    • Trapp, B.D.1
  • 36
    • 0021838039 scopus 로고
    • A quantitation of myelin-associated glycoprotein and myelin basic protein loss in different demyelinating diseases
    • Gendelman HE, Pezeshkpour GH, Pressman NJ, et al. A quantitation of myelin-associated glycoprotein and myelin basic protein loss in different demyelinating diseases. Ann Neurol 1985; 18:324-329
    • (1985) Ann Neurol , vol.18 , pp. 324-329
    • Gendelman, H.E.1    Pezeshkpour, G.H.2    Pressman, N.J.3
  • 37
    • 0021239052 scopus 로고
    • The distribution of myelin-associated glycoprotein and myelin basic protein in actively demyelinating multiple sclerosis lesions
    • Prineas JW, Kwon EE, Sternberger NH, Lennon VA. The distribution of myelin-associated glycoprotein and myelin basic protein in actively demyelinating multiple sclerosis lesions. J Neuroimmunol 1984;6:251-264
    • (1984) J Neuroimmunol , vol.6 , pp. 251-264
    • Prineas, J.W.1    Kwon, E.E.2    Sternberger, N.H.3    Lennon, V.A.4
  • 38
    • 0019468510 scopus 로고
    • Evidence of a "dying-back" gliopathy in demyelinating disease
    • Ludwin SK, Johnson ES. Evidence of a "dying-back" gliopathy in demyelinating disease. Ann Neurol 1981;9:301-305
    • (1981) Ann Neurol , vol.9 , pp. 301-305
    • Ludwin, S.K.1    Johnson, E.S.2
  • 39
    • 0022253157 scopus 로고
    • Virus-induced demyelination in mice: "Dying-back" of oligodendrocytes
    • Rodriguez M: Virus-induced demyelination in mice: "dying-back" of oligodendrocytes. Mayo Clin Proc 1995;60:433-438
    • (1995) Mayo Clin Proc , vol.60 , pp. 433-438
    • Rodriguez, M.1
  • 40
    • 0031081587 scopus 로고    scopus 로고
    • Dying-back oligodendrogliopathy: A late sequel of myelin-associated glycoprotein deficiency
    • Lassmann H, Bartsch U, Montag D, Schachner M. Dying-back oligodendrogliopathy: a late sequel of myelin-associated glycoprotein deficiency. Glia 1997;19:104-110.5
    • (1997) Glia , vol.19 , pp. 104-1105
    • Lassmann, H.1    Bartsch, U.2    Montag, D.3    Schachner, M.4
  • 41
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983:227-231
    • (1983) Ann Neurol , pp. 227-231
    • Poser, C.M.1    Paty, D.W.2    Scheinberg, L.3
  • 42
    • 0025999066 scopus 로고
    • Detection of a monocyte/macrophage differentiation antigen in routinely processed paraffin-embedded tissues by monoclonal antibody Ki-M1P
    • Radzun HJ, Hansmann ML, Heidebrecht HJ, et al. Detection of a monocyte/macrophage differentiation antigen in routinely processed paraffin-embedded tissues by monoclonal antibody Ki-M1P. Lab Invest 1991;65:306-315
    • (1991) Lab Invest , vol.65 , pp. 306-315
    • Radzun, H.J.1    Hansmann, M.L.2    Heidebrecht, H.J.3
  • 43
    • 0021917632 scopus 로고
    • Generation and characterization of mouse monoclonal antibodies to myelin-associated glycoprorein (MAG)
    • Dobersen MJ, Hammer JA, Noronha AB, et al. Generation and characterization of mouse monoclonal antibodies to myelin-associated glycoprorein (MAG). Neurochem Res 1985;10:499-513
    • (1985) Neurochem Res , vol.10 , pp. 499-513
    • Dobersen, M.J.1    Hammer, J.A.2    Noronha, A.B.3
  • 44
    • 0025203934 scopus 로고
    • Myelin/oligodendrocyte glycoprotein expression during development in normal and myelin-deficient mice
    • Matthieu J-M, Amiguet P. Myelin/oligodendrocyte glycoprotein expression during development in normal and myelin-deficient mice. Dev Neurosci 1990;12:293-302
    • (1990) Dev Neurosci , vol.12 , pp. 293-302
    • Matthieu, J.-M.1    Amiguet, P.2
  • 45
    • 0027733797 scopus 로고
    • The demyelinating potential of antibodies to myelin oligodendroglia glycoprotein is related to their ability to fix complement
    • Piddlesden S, Lassmann H, Zimprich F, et al. The demyelinating potential of antibodies to myelin oligodendroglia glycoprotein is related to their ability to fix complement. Am J Pathol 1993;143:555-564
    • (1993) Am J Pathol , vol.143 , pp. 555-564
    • Piddlesden, S.1    Lassmann, H.2    Zimprich, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.