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Volumn 210, Issue 1-2, 2009, Pages 92-99

α4 Integrin/FN-CS1 mediated leukocyte adhesion to brain microvascular endothelial cells under flow conditions

Author keywords

4 integrin; Adhesion; Blood brain barrier; Chemokines; Leukocyte; Multiple sclerosis; Shear stress

Indexed keywords

ALPHA4 INTEGRIN; BETA1A INTERFERON; CHEMOKINE; CYTOKINE; FIBRONECTIN; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON; NATALIZUMAB; PERTUSSIS TOXIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; MONOCLONAL ANTIBODY;

EID: 67349218765     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.03.008     Document Type: Article
Times cited : (49)

References (61)
  • 1
  • 4
    • 3242726945 scopus 로고    scopus 로고
    • CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer
    • Callahan M.K., Williams K.A., Kivisakk P., Pearce D., Stins M.F., and Ransohoff R.M. CXCR3 marks CD4+ memory T lymphocytes that are competent to migrate across a human brain microvascular endothelial cell layer. J. Neuroimmunol. 153 (2004) 150-157
    • (2004) J. Neuroimmunol. , vol.153 , pp. 150-157
    • Callahan, M.K.1    Williams, K.A.2    Kivisakk, P.3    Pearce, D.4    Stins, M.F.5    Ransohoff, R.M.6
  • 5
    • 7244248569 scopus 로고    scopus 로고
    • A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them
    • Carman C.V., and Springer T.A. A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them. J. Cell Biol. 167 (2004) 377-388
    • (2004) J. Cell Biol. , vol.167 , pp. 377-388
    • Carman, C.V.1    Springer, T.A.2
  • 6
    • 41349097097 scopus 로고    scopus 로고
    • STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier
    • Chaudhuri A., Yang B., Gendelman H.E., Persidsky Y., and Kanmogne G.D. STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier. Blood 111 (2008) 2062-2072
    • (2008) Blood , vol.111 , pp. 2062-2072
    • Chaudhuri, A.1    Yang, B.2    Gendelman, H.E.3    Persidsky, Y.4    Kanmogne, G.D.5
  • 8
    • 0037312886 scopus 로고    scopus 로고
    • Inflammatory mechanisms after ischemia and stroke
    • Danton G.H., and Dietrich W.D. Inflammatory mechanisms after ischemia and stroke. J. Neuropathol. Exp. Neurol. 62 (2003) 127-136
    • (2003) J. Neuropathol. Exp. Neurol. , vol.62 , pp. 127-136
    • Danton, G.H.1    Dietrich, W.D.2
  • 9
    • 33947193936 scopus 로고    scopus 로고
    • VCAM-1 activation of endothelial cell protein tyrosine phosphatase 1
    • Deem T.L., bdala-Valencia H., and Cook-Mills J.M. VCAM-1 activation of endothelial cell protein tyrosine phosphatase 1. B. J. Immunol. 178 (2007) 3865-3873
    • (2007) B. J. Immunol. , vol.178 , pp. 3865-3873
    • Deem, T.L.1    bdala-Valencia, H.2    Cook-Mills, J.M.3
  • 10
    • 40049095589 scopus 로고    scopus 로고
    • E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice
    • Doring A., Wild M., Vestweber D., Deutsch U., and Engelhardt B. E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice. J. Immunol. 179 (2007) 8470-8479
    • (2007) J. Immunol. , vol.179 , pp. 8470-8479
    • Doring, A.1    Wild, M.2    Vestweber, D.3    Deutsch, U.4    Engelhardt, B.5
  • 11
    • 0025161990 scopus 로고
    • VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site
    • Elices M.J., Osborn L., Takada Y., Crouse C., Luhowskyj S., Hemler M.E., and Lobb R.R. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60 (1990) 577-584
    • (1990) Cell , vol.60 , pp. 577-584
    • Elices, M.J.1    Osborn, L.2    Takada, Y.3    Crouse, C.4    Luhowskyj, S.5    Hemler, M.E.6    Lobb, R.R.7
  • 13
    • 23744475685 scopus 로고    scopus 로고
    • The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms
    • Engelhardt B., and Ransohoff R.M. The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms. Trends Immunol. 26 (2005) 485-495
    • (2005) Trends Immunol. , vol.26 , pp. 485-495
    • Engelhardt, B.1    Ransohoff, R.M.2
  • 14
    • 9244250315 scopus 로고    scopus 로고
    • Mini-review: Transendothelial migration of leukocytes: through the front door or around the side of the house?
    • Engelhardt B., and Wolburg H. Mini-review: Transendothelial migration of leukocytes: through the front door or around the side of the house?. Eur. J. Immunol. 34 (2004) 2955-2963
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2955-2963
    • Engelhardt, B.1    Wolburg, H.2
  • 15
    • 57649219453 scopus 로고    scopus 로고
    • Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells
    • Ganji S.H., Qin S., Zhang L., Kamanna V.S., and Kashyap M.L. Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells. Atherosclerosis 202 (2009) 68-75
    • (2009) Atherosclerosis , vol.202 , pp. 68-75
    • Ganji, S.H.1    Qin, S.2    Zhang, L.3    Kamanna, V.S.4    Kashyap, M.L.5
  • 16
    • 0025124607 scopus 로고
    • Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1
    • Guan J.L., and Hynes R.O. Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. Cell 60 (1990) 53-61
    • (1990) Cell , vol.60 , pp. 53-61
    • Guan, J.L.1    Hynes, R.O.2
  • 17
    • 0006457649 scopus 로고
    • Identification of a third region of cell-specific alternative splicing in human fibronectin mRNA
    • Gutman A., and Kornblihtt A.R. Identification of a third region of cell-specific alternative splicing in human fibronectin mRNA. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 7179-7182
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 7179-7182
    • Gutman, A.1    Kornblihtt, A.R.2
  • 19
    • 54249115529 scopus 로고    scopus 로고
    • A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells
    • Hartmann T.N., Grabovsky V., Pasvolsky R., Shulman Z., Buss E.C., Spiegel A., Nagler A., Lapidot T., Thelen M., and Alon R. A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells. J. Leukoc. Biol. 84 (2008) 1130-1140
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 1130-1140
    • Hartmann, T.N.1    Grabovsky, V.2    Pasvolsky, R.3    Shulman, Z.4    Buss, E.C.5    Spiegel, A.6    Nagler, A.7    Lapidot, T.8    Thelen, M.9    Alon, R.10
  • 20
    • 0025218924 scopus 로고
    • VLA proteins in the integrin family: structures, functions, and their role on leukocytes
    • Hemler M.E. VLA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu. Rev. Immunol. 8 (1990) 365-400
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 365-400
    • Hemler, M.E.1
  • 21
    • 0030047410 scopus 로고    scopus 로고
    • Heterogeneous autoregulation of cerebrocortical capillary flow: evidence for functional thoroughfare channels?
    • Hudetz A.G., Fehér G., and Kampine J.P. Heterogeneous autoregulation of cerebrocortical capillary flow: evidence for functional thoroughfare channels?. Microvasc. Res. 51 (1996) 131-136
    • (1996) Microvasc. Res. , vol.51 , pp. 131-136
    • Hudetz, A.G.1    Fehér, G.2    Kampine, J.P.3
  • 23
    • 0034068610 scopus 로고    scopus 로고
    • Cytokine-induced modulation of cellular adhesion to human cerebral endothelial cells is mediated by soluble vascular cell adhesion molecule-1
    • Kallmann B.A., Hummel V., Lindenlaub T., Ruprecht K., Toyka K.V., and Rieckmann P. Cytokine-induced modulation of cellular adhesion to human cerebral endothelial cells is mediated by soluble vascular cell adhesion molecule-1. Brain 123 Pt 4 (2000) 687-697
    • (2000) Brain , vol.123 , Issue.PART 4 , pp. 687-697
    • Kallmann, B.A.1    Hummel, V.2    Lindenlaub, T.3    Ruprecht, K.4    Toyka, K.V.5    Rieckmann, P.6
  • 24
    • 0028987311 scopus 로고
    • A monoclonal antibody to alpha 4 integrin suppresses and reverses active experimental allergic encephalomyelitis
    • Kent S.J., Karlik S.J., Cannon C., Hines D.K., Yednock T.A., Fritz L.C., and Horner H.C. A monoclonal antibody to alpha 4 integrin suppresses and reverses active experimental allergic encephalomyelitis. J. Neuroimmunol. 58 (1995) 1-10
    • (1995) J. Neuroimmunol. , vol.58 , pp. 1-10
    • Kent, S.J.1    Karlik, S.J.2    Cannon, C.3    Hines, D.K.4    Yednock, T.A.5    Fritz, L.C.6    Horner, H.C.7
  • 27
    • 3843101531 scopus 로고    scopus 로고
    • Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro
    • Kraus J., Ling A.K., Hamm S., Voigt K., Oschmann P., and Engelhardt B. Interferon-beta stabilizes barrier characteristics of brain endothelial cells in vitro. Ann. Neurol. 56 (2004) 192-205
    • (2004) Ann. Neurol. , vol.56 , pp. 192-205
    • Kraus, J.1    Ling, A.K.2    Hamm, S.3    Voigt, K.4    Oschmann, P.5    Engelhardt, B.6
  • 28
    • 55449137632 scopus 로고    scopus 로고
    • Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis
    • Krumbholz M., Meinl I., Kümpfel T., Hohlfeld R., and Meinl E. Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis. Neurology 71 (2008) 1350-1354
    • (2008) Neurology , vol.71 , pp. 1350-1354
    • Krumbholz, M.1    Meinl, I.2    Kümpfel, T.3    Hohlfeld, R.4    Meinl, E.5
  • 29
    • 1842588603 scopus 로고    scopus 로고
    • Structural pathways for macromolecular and cellular transport across the blood-brain barrier during inflammatory conditions. Review
    • Lossinsky A.S., and Shivers R.R. Structural pathways for macromolecular and cellular transport across the blood-brain barrier during inflammatory conditions. Review. Histol. Histopathol. 19 (2004) 535-564
    • (2004) Histol. Histopathol. , vol.19 , pp. 535-564
    • Lossinsky, A.S.1    Shivers, R.R.2
  • 30
    • 0036696096 scopus 로고    scopus 로고
    • The role of endothelial cell lateral junctions during leukocyte trafficking
    • Luscinskas F.W., Ma S., Nusrat A., Parkos C.A., and Shaw S.K. The role of endothelial cell lateral junctions during leukocyte trafficking. Immunol. Rev. 186 (2002) 57-67
    • (2002) Immunol. Rev. , vol.186 , pp. 57-67
    • Luscinskas, F.W.1    Ma, S.2    Nusrat, A.3    Parkos, C.A.4    Shaw, S.K.5
  • 31
    • 30044447736 scopus 로고    scopus 로고
    • Immune cell migration in inflammation: present and future therapeutic targets
    • Luster A.D., Alon R., and Von Andrian U.H. Immune cell migration in inflammation: present and future therapeutic targets. Nat. Immunol. 6 (2005) 1182-1190
    • (2005) Nat. Immunol. , vol.6 , pp. 1182-1190
    • Luster, A.D.1    Alon, R.2    Von Andrian, U.H.3
  • 33
    • 33947543465 scopus 로고    scopus 로고
    • Inflammatory cell migration into the central nervous system: a few new twists on an old tale
    • Man S., Ubogu E.E., and Ransohoff R.M. Inflammatory cell migration into the central nervous system: a few new twists on an old tale. Brain Pathol. 17 (2007) 243-250
    • (2007) Brain Pathol. , vol.17 , pp. 243-250
    • Man, S.1    Ubogu, E.E.2    Ransohoff, R.M.3
  • 34
    • 41149178098 scopus 로고    scopus 로고
    • Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migration
    • Man S., Ubogu E.E., Williams K.A., Tucky B., Callahan M.K., and Ransohoff R.M. Human brain microvascular endothelial cells and umbilical vein endothelial cells differentially facilitate leukocyte recruitment and utilize chemokines for T cell migration. Clin. Dev. Immunol. 2008 (2008) 384982
    • (2008) Clin. Dev. Immunol. , vol.2008 , pp. 384982
    • Man, S.1    Ubogu, E.E.2    Williams, K.A.3    Tucky, B.4    Callahan, M.K.5    Ransohoff, R.M.6
  • 36
    • 40449087213 scopus 로고    scopus 로고
    • Pathological expression of CXCL12 at the blood-brain barrier correlates with severity of multiple sclerosis
    • McCandless E.E., Piccio L., Woerner B.M., Schmidt R.E., Rubin J.B., Cross A.H., and Klein R.S. Pathological expression of CXCL12 at the blood-brain barrier correlates with severity of multiple sclerosis. Am. J. Pathol. 172 (2008) 799-808
    • (2008) Am. J. Pathol. , vol.172 , pp. 799-808
    • McCandless, E.E.1    Piccio, L.2    Woerner, B.M.3    Schmidt, R.E.4    Rubin, J.B.5    Cross, A.H.6    Klein, R.S.7
  • 37
    • 45849086857 scopus 로고    scopus 로고
    • Antioxidative pyranonigrins in rice mold starters and their suppressive effect on the expression of blood adhesion molecules
    • Miyake Y., Mochizuki M., Ito C., Itoigawa M., and Osawa T. Antioxidative pyranonigrins in rice mold starters and their suppressive effect on the expression of blood adhesion molecules. Biosci. Biotechnol. Biochem. 72 (2008) 1580-1585
    • (2008) Biosci. Biotechnol. Biochem. , vol.72 , pp. 1580-1585
    • Miyake, Y.1    Mochizuki, M.2    Ito, C.3    Itoigawa, M.4    Osawa, T.5
  • 38
    • 0032559851 scopus 로고    scopus 로고
    • Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization
    • Navarro P., Ruco L., and Dejana E. Differential localization of VE- and N-cadherins in human endothelial cells: VE-cadherin competes with N-cadherin for junctional localization. J. Cell. Biol. 140 (1998) 1475-1484
    • (1998) J. Cell. Biol. , vol.140 , pp. 1475-1484
    • Navarro, P.1    Ruco, L.2    Dejana, E.3
  • 42
    • 34250779802 scopus 로고    scopus 로고
    • Natalizumab for multiple sclerosis
    • Ransohoff R.M. Natalizumab for multiple sclerosis. N. Engl. J. Med. 356 (2007) 2622-2629
    • (2007) N. Engl. J. Med. , vol.356 , pp. 2622-2629
    • Ransohoff, R.M.1
  • 43
    • 33846927197 scopus 로고    scopus 로고
    • "Doing the locomotion" with the multistep paradigm
    • Ransohoff R.M., Man S., and Ubogu E.E. "Doing the locomotion" with the multistep paradigm. Blood 109 (2007) 1342-1343
    • (2007) Blood , vol.109 , pp. 1342-1343
    • Ransohoff, R.M.1    Man, S.2    Ubogu, E.E.3
  • 44
    • 17644398787 scopus 로고    scopus 로고
    • Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale
    • Rice G.P., Hartung H.P., and Calabresi P.A. Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale. Neurology 64 (2005) 1336-1342
    • (2005) Neurology , vol.64 , pp. 1336-1342
    • Rice, G.P.1    Hartung, H.P.2    Calabresi, P.A.3
  • 46
    • 33846918610 scopus 로고    scopus 로고
    • Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm
    • Schreiber T.H., Shinder V., Cain D.W., Alon R., and Sackstein R. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm. Blood 109 (2007) 1381-1386
    • (2007) Blood , vol.109 , pp. 1381-1386
    • Schreiber, T.H.1    Shinder, V.2    Cain, D.W.3    Alon, R.4    Sackstein, R.5
  • 48
    • 33748304311 scopus 로고    scopus 로고
    • DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration
    • Shulman Z., Pasvolsky R., Woolf E., Grabovsky V., Feigelson S.W., Erez N., Fukui Y., and Alon R. DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration. Blood 108 (2006) 2150-2158
    • (2006) Blood , vol.108 , pp. 2150-2158
    • Shulman, Z.1    Pasvolsky, R.2    Woolf, E.3    Grabovsky, V.4    Feigelson, S.W.5    Erez, N.6    Fukui, Y.7    Alon, R.8
  • 49
    • 0028141376 scopus 로고
    • Engagement of the common leukocyte antigen CD45 induces homotypic adhesion of activated human T cells
    • Spertini F., Wang A.V., Chatila T., and Geha R.S. Engagement of the common leukocyte antigen CD45 induces homotypic adhesion of activated human T cells. J. Immunol. 153 (1994) 1593-1602
    • (1994) J. Immunol. , vol.153 , pp. 1593-1602
    • Spertini, F.1    Wang, A.V.2    Chatila, T.3    Geha, R.S.4
  • 50
    • 0030917425 scopus 로고    scopus 로고
    • Selective expression of adhesion molecules on human brain microvascular endothelial cells
    • Stins M.F., Gilles F., and Kim K.S. Selective expression of adhesion molecules on human brain microvascular endothelial cells. J. Neuroimmunol. 76 (1997) 81-90
    • (1997) J. Neuroimmunol. , vol.76 , pp. 81-90
    • Stins, M.F.1    Gilles, F.2    Kim, K.S.3
  • 51
    • 0033999986 scopus 로고    scopus 로고
    • Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin
    • Ting K.M., Rothaupt D., McCormick T.S., Hammerberg C., Chen G., Gilliam A.C., Stevens S., Culp L., and Cooper K.D. Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin. J. Invest. Dermatol. 114 (2000) 706-711
    • (2000) J. Invest. Dermatol. , vol.114 , pp. 706-711
    • Ting, K.M.1    Rothaupt, D.2    McCormick, T.S.3    Hammerberg, C.4    Chen, G.5    Gilliam, A.C.6    Stevens, S.7    Culp, L.8    Cooper, K.D.9
  • 52
    • 33749128330 scopus 로고    scopus 로고
    • Determinants of CCL5-driven mononuclear cell migration across the blood-brain barrier. Implications for therapeutically modulating neuroinflammation
    • Ubogu E.E., Callahan M.K., Tucky B.H., and Ransohoff R.M. Determinants of CCL5-driven mononuclear cell migration across the blood-brain barrier. Implications for therapeutically modulating neuroinflammation. J. Neuroimmunol. 179 (2006) 132-144
    • (2006) J. Neuroimmunol. , vol.179 , pp. 132-144
    • Ubogu, E.E.1    Callahan, M.K.2    Tucky, B.H.3    Ransohoff, R.M.4
  • 54
    • 23844503579 scopus 로고    scopus 로고
    • Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes
    • Van H.J., Bo L., Vos C.M., Virtanen I., and De Vries H.E. Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes. J. Neuropathol. Exp. Neurol. 64 (2005) 722-729
    • (2005) J. Neuropathol. Exp. Neurol. , vol.64 , pp. 722-729
    • Van, H.J.1    Bo, L.2    Vos, C.M.3    Virtanen, I.4    De Vries, H.E.5
  • 55
    • 0037413240 scopus 로고    scopus 로고
    • Alpha4 integrins as therapeutic targets in autoimmune disease
    • Von Andrian U.H., and Engelhardt B. Alpha4 integrins as therapeutic targets in autoimmune disease. N. Engl. J. Med. 348 (2003) 68-72
    • (2003) N. Engl. J. Med. , vol.348 , pp. 68-72
    • Von Andrian, U.H.1    Engelhardt, B.2
  • 56
    • 2642563866 scopus 로고    scopus 로고
    • Molecular anatomy of interendothelial junctions in human blood-brain barrier microvessels
    • Vorbrodt A.W., and Dobrogowska D.H. Molecular anatomy of interendothelial junctions in human blood-brain barrier microvessels. Folia Histochem. Cytobiol. 42 (2004) 67-75
    • (2004) Folia Histochem. Cytobiol. , vol.42 , pp. 67-75
    • Vorbrodt, A.W.1    Dobrogowska, D.H.2
  • 57
    • 0033857526 scopus 로고    scopus 로고
    • Differentiation of polymorphonuclear neutrophils in patients with systemic infections and chronic inflammatory diseases: evidence of prolonged life span and de novo synthesis of fibronectin
    • Wagner C., Pioch M., Meyer C., Iking-Konert C., Andrassy K., and Hansch G.M. Differentiation of polymorphonuclear neutrophils in patients with systemic infections and chronic inflammatory diseases: evidence of prolonged life span and de novo synthesis of fibronectin. J. Mol. Med. 78 (2000) 337-345
    • (2000) J. Mol. Med. , vol.78 , pp. 337-345
    • Wagner, C.1    Pioch, M.2    Meyer, C.3    Iking-Konert, C.4    Andrassy, K.5    Hansch, G.M.6
  • 58
    • 47749105350 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 infection increases the in vivo capacity of peripheral monocytes to cross the blood-brain barrier into the brain and the in vivo sensitivity of the blood-brain barrier to disruption by lipopolysaccharide
    • Wang H., Sun J., and Goldstein H. Human immunodeficiency virus type 1 infection increases the in vivo capacity of peripheral monocytes to cross the blood-brain barrier into the brain and the in vivo sensitivity of the blood-brain barrier to disruption by lipopolysaccharide. J. Virol. 82 (2008) 7591-7600
    • (2008) J. Virol. , vol.82 , pp. 7591-7600
    • Wang, H.1    Sun, J.2    Goldstein, H.3
  • 59
    • 12244252762 scopus 로고    scopus 로고
    • Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor- and interleukin-1-related gene polymorphisms
    • Watanabe E., Hirasawa H., Oda S., Matsuda K., Hatano M., and Tokuhisa T. Extremely high interleukin-6 blood levels and outcome in the critically ill are associated with tumor necrosis factor- and interleukin-1-related gene polymorphisms. Crit. Care Med. 33 (2005) 89-97
    • (2005) Crit. Care Med. , vol.33 , pp. 89-97
    • Watanabe, E.1    Hirasawa, H.2    Oda, S.3    Matsuda, K.4    Hatano, M.5    Tokuhisa, T.6
  • 60
    • 0033030208 scopus 로고    scopus 로고
    • In vitro adhesion and migration of T lymphocytes across monolayers of human brain microvessel endothelial cells: regulation by ICAM-1, VCAM-1, E-selectin and PECAM-1
    • Wong D., Prameya R., and Dorovini-Zis K. In vitro adhesion and migration of T lymphocytes across monolayers of human brain microvessel endothelial cells: regulation by ICAM-1, VCAM-1, E-selectin and PECAM-1. J. Neuropathol. Exp. Neurol. 58 (1999) 138-152
    • (1999) J. Neuropathol. Exp. Neurol. , vol.58 , pp. 138-152
    • Wong, D.1    Prameya, R.2    Dorovini-Zis, K.3
  • 61


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