메뉴 건너뛰기




Volumn 46, Issue 3, 1999, Pages 296-304

Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; METHYLPREDNISOLONE; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 0032882173     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(199909)46:3<296::aid-ana4>3.0.co;2-%23     Document Type: Article
Times cited : (475)

References (43)
  • 1
    • 0022642908 scopus 로고
    • Induction of tolerance by monoclonal antibody therapy
    • Benjamin RJ, Waldmann H. Induction of tolerance by monoclonal antibody therapy. Nature 1986;320:449-451
    • (1986) Nature , vol.320 , pp. 449-451
    • Benjamin, R.J.1    Waldmann, H.2
  • 2
    • 0027479685 scopus 로고
    • "Infectious" transplantation tolerance
    • Qin S, Cobbold SP, Pope H, et al. "Infectious" transplantation tolerance. Science 1993;259:974-977
    • (1993) Science , vol.259 , pp. 974-977
    • Qin, S.1    Cobbold, S.P.2    Pope, H.3
  • 3
    • 0028346432 scopus 로고
    • Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis
    • published erratum. Lancet 1994;344:486
    • Moreau T, Thorpe J, Miller D, et al. Preliminary evidence from magnetic resonance imaging for reduction in disease activity after lymphocyte depletion in multiple sclerosis [published erratum. Lancet 1994;344:486]. Lancet 1994;344:298-301
    • (1994) Lancet , vol.344 , pp. 298-301
    • Moreau, T.1    Thorpe, J.2    Miller, D.3
  • 4
    • 0029869119 scopus 로고    scopus 로고
    • Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis
    • Moreau T, Coles A, Wing M, et al. Transient increase in symptoms associated with cytokine release in patients with multiple sclerosis. Brain 1996;119:225-237
    • (1996) Brain , vol.119 , pp. 225-237
    • Moreau, T.1    Coles, A.2    Wing, M.3
  • 5
    • 0027076729 scopus 로고
    • Evidence that antihuman tumor necrosis factor monoclonal antibody prevents OKT3-induced acute syndrome
    • Charpentier B, Hiesse C, Lantz O, et al. Evidence that antihuman tumor necrosis factor monoclonal antibody prevents OKT3-induced acute syndrome. Transplantation 1992;54:997-1002
    • (1992) Transplantation , vol.54 , pp. 997-1002
    • Charpentier, B.1    Hiesse, C.2    Lantz, O.3
  • 6
    • 0025949863 scopus 로고
    • Cascade modulation by anti-tumor necrosis factor monoclonal antibody of interferon-gamma, interleukin 3 and interleukin 6 release after triggering of the CD3/T cell receptor activation pathway
    • Ferran C, Dy M, Sheehan K, et al. Cascade modulation by anti-tumor necrosis factor monoclonal antibody of interferon-gamma, interleukin 3 and interleukin 6 release after triggering of the CD3/T cell receptor activation pathway. Eur J Immunol 1991;21:2349-2353
    • (1991) Eur J Immunol , vol.21 , pp. 2349-2353
    • Ferran, C.1    Dy, M.2    Sheehan, K.3
  • 7
    • 85080543929 scopus 로고    scopus 로고
    • Quantitative MRI in patients with secondary progressive MS treated monoclonal antibody, Campath-1H
    • In press
    • Paolillo A, Coles A, Molyneux P, et al. Quantitative MRI in patients with secondary progressive MS treated monoclonal antibody, Campath-1H. Neurology (In press)
    • Neurology
    • Paolillo, A.1    Coles, A.2    Molyneux, P.3
  • 8
    • 0021035886 scopus 로고
    • Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
    • Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33: 1444-1452
    • (1983) Neurology , vol.33 , pp. 1444-1452
    • Kurtzke, J.F.1
  • 9
    • 0026002097 scopus 로고
    • A specific and reliable bioassay for the detection of femtomolar levels of human and murine tumor necrosis factors
    • Branch DR, Shah A, Guilbert LJ. A specific and reliable bioassay for the detection of femtomolar levels of human and murine tumor necrosis factors. J Immunol Methods 1991;143:251-261
    • (1991) J Immunol Methods , vol.143 , pp. 251-261
    • Branch, D.R.1    Shah, A.2    Guilbert, L.J.3
  • 10
    • 0024947945 scopus 로고
    • Studies on the specificity of the L929 cell bioassay for the measurement of tumour necrosis factor
    • Hay H, Cohen J. Studies on the specificity of the L929 cell bioassay for the measurement of tumour necrosis factor. J Clin Lab Immunol 1989;29:151-155
    • (1989) J Clin Lab Immunol , vol.29 , pp. 151-155
    • Hay, H.1    Cohen, J.2
  • 11
    • 0030453516 scopus 로고    scopus 로고
    • Progressive cerebral atrophy in multiple sclerosis: A serial MRI study
    • Losseff NA, Wang L, Lai HM, et al. Progressive cerebral atrophy in multiple sclerosis: a serial MRI study. Brain 1996;119: 2009-2019
    • (1996) Brain , vol.119 , pp. 2009-2019
    • Losseff, N.A.1    Wang, L.2    Lai, H.M.3
  • 12
    • 0020686503 scopus 로고
    • New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
    • Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-231
    • (1983) Ann Neurol , vol.13 , pp. 227-231
    • Poser, C.M.1    Paty, D.W.2    Scheinberg, L.3
  • 13
    • 0026323045 scopus 로고
    • The pathophysiology of acute optic neuritis: An association of gadolinium leakage with clinical and electrophysiological deficits
    • Youl BD, Turano G, Miller DH, et al. The pathophysiology of acute optic neuritis: an association of gadolinium leakage with clinical and electrophysiological deficits. Brain 1991;114:2437-2450
    • (1991) Brain , vol.114 , pp. 2437-2450
    • Youl, B.D.1    Turano, G.2    Miller, D.H.3
  • 14
    • 0017191362 scopus 로고
    • Experimental studies of the effects of extrinsic factors on conduction in normal and demyelinated nerve. 1. Temperature
    • Davis FA, Schauf CL, Reed BJ, Kesler RL. Experimental studies of the effects of extrinsic factors on conduction in normal and demyelinated nerve. 1. Temperature. J Neurol Neurosurg Psychiatry 1976;39:442-448
    • (1976) J Neurol Neurosurg Psychiatry , vol.39 , pp. 442-448
    • Davis, F.A.1    Schauf, C.L.2    Reed, B.J.3    Kesler, R.L.4
  • 15
    • 0017148934 scopus 로고
    • Neuroelectric blocking factors in human and animal sera evaluated using the isolated frog spinal cord
    • Schauf CL, Davis FA, Sack DA, et al. Neuroelectric blocking factors in human and animal sera evaluated using the isolated frog spinal cord. J Neurol Neurosurg Psychiatry 1976;39: 680-685
    • (1976) J Neurol Neurosurg Psychiatry , vol.39 , pp. 680-685
    • Schauf, C.L.1    Davis, F.A.2    Sack, D.A.3
  • 16
    • 0031439343 scopus 로고    scopus 로고
    • Nitric oxide donors reversibly block axonal conduction: Demyelinated axons are especially susceptible
    • Redford EJ, Kapoor R, Smith KJ. Nitric oxide donors reversibly block axonal conduction: demyelinated axons are especially susceptible. Brain 1997;120:2149-2157
    • (1997) Brain , vol.120 , pp. 2149-2157
    • Redford, E.J.1    Kapoor, R.2    Smith, K.J.3
  • 17
    • 0028107813 scopus 로고
    • Follow-up study of MS patients treated with high-dose intravenous methylprednisolone
    • Frequin ST, Lamers KJ, Barkhof F, et al. Follow-up study of MS patients treated with high-dose intravenous methylprednisolone. Acta Neurol Scand 1994;90:105-110
    • (1994) Acta Neurol Scand , vol.90 , pp. 105-110
    • Frequin, S.T.1    Lamers, K.J.2    Barkhof, F.3
  • 18
    • 0023194967 scopus 로고
    • A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 1. Clinical effects
    • Milligan NM, Newcombe R, Compston DA. A double-blind controlled trial of high dose methylprednisolone in patients with multiple sclerosis: 1. Clinical effects. J Neurol Neurosurg Psychiatry 1987;50:511-516
    • (1987) J Neurol Neurosurg Psychiatry , vol.50 , pp. 511-516
    • Milligan, N.M.1    Newcombe, R.2    Compston, D.A.3
  • 19
    • 0029751983 scopus 로고    scopus 로고
    • Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2
    • Van Oosten BW, Barkhof F, Truyen L, et al. Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. Neurology 1996;47:1531-1534
    • (1996) Neurology , vol.47 , pp. 1531-1534
    • Van Oosten, B.W.1    Barkhof, F.2    Truyen, L.3
  • 20
    • 0028143212 scopus 로고
    • Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, et al. Repeated therapy with monoclonal antibody to tumour necrosis factor alpha (cA2) in patients with rheumatoid arthritis. Lancet 1994;344: 1125-1127
    • (1994) Lancet , vol.344 , pp. 1125-1127
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 21
    • 0028143211 scopus 로고
    • Randomised doubleblind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, et al. Randomised doubleblind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-1110
    • (1994) Lancet , vol.344 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 22
    • 0030773332 scopus 로고    scopus 로고
    • Characterization of MRI response to treatment with interferon beta-1b: Contrast-enhancing MRI lesion frequency as a primary outcome measure
    • Stone LA, Frank JA, Albert PS, et al. Characterization of MRI response to treatment with Interferon beta-Ib: contrast-enhancing MRI lesion frequency as a primary outcome measure. Neurology 1997;49:862-869
    • (1997) Neurology , vol.49 , pp. 862-869
    • Stone, L.A.1    Frank, J.A.2    Albert, P.S.3
  • 23
    • 0028922832 scopus 로고
    • Does interferon beta cause initial exacerbation of multiple sclerosis?
    • Letter
    • Rudge P, Miller D, Crimlisk H, Thorpe J. Does Interferon beta cause initial exacerbation of multiple sclerosis? Lancet 1995; 345:580 (Letter)
    • (1995) Lancet , vol.345 , pp. 580
    • Rudge, P.1    Miller, D.2    Crimlisk, H.3    Thorpe, J.4
  • 24
    • 0029431903 scopus 로고
    • Changes in the amount of diseased white matter over time in patients with relapsing-remitting multiple sclerosis
    • Stone LA, Albert PS, Smith ME, et al. Changes in the amount of diseased white matter over time in patients with relapsing-remitting multiple sclerosis. Neurology 1995;45:1808-1814
    • (1995) Neurology , vol.45 , pp. 1808-1814
    • Stone, L.A.1    Albert, P.S.2    Smith, M.E.3
  • 25
    • 0031891592 scopus 로고    scopus 로고
    • Correlations between monthly enhanced MRI lesion rate and changes in T2 lesion volume in multiple sclerosis
    • Molyneux PD, Filippi M, Barkhof F, et al. Correlations between monthly enhanced MRI lesion rate and changes in T2 lesion volume in multiple sclerosis. Ann Neurol 1998;43: 332-339
    • (1998) Ann Neurol , vol.43 , pp. 332-339
    • Molyneux, P.D.1    Filippi, M.2    Barkhof, F.3
  • 26
    • 0025906369 scopus 로고
    • Patterns of blood-brain barrier breakdown in inflammatory demyelination
    • Hawkins CP, Mackenzie F, Tofts P, et al. Patterns of blood-brain barrier breakdown in inflammatory demyelination. Brain 1991;114:801-810
    • (1991) Brain , vol.114 , pp. 801-810
    • Hawkins, C.P.1    Mackenzie, F.2    Tofts, P.3
  • 27
    • 0027503708 scopus 로고
    • Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis
    • Katz D, Taubenberger JK, Cannella B, et al. Correlation between magnetic resonance imaging findings and lesion development in chronic, active multiple sclerosis. Ann Neurol 1993;34: 661-669
    • (1993) Ann Neurol , vol.34 , pp. 661-669
    • Katz, D.1    Taubenberger, J.K.2    Cannella, B.3
  • 28
    • 0030780349 scopus 로고    scopus 로고
    • Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology
    • Bruck W, Bitsch A, Kolenda H, et al. Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology. Ann Neurol 1997;42:783-793
    • (1997) Ann Neurol , vol.42 , pp. 783-793
    • Bruck, W.1    Bitsch, A.2    Kolenda, H.3
  • 29
    • 0030880011 scopus 로고    scopus 로고
    • Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412; results of a randomized, double-blind, placebo-controlled, MR-monitored phase II trial
    • Van Oosten BW, Lai M, Hodgkinson S, et al. Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412; results of a randomized, double-blind, placebo-controlled, MR-monitored phase II trial. Neurology 1997;49: 351-357
    • (1997) Neurology , vol.49 , pp. 351-357
    • Van Oosten, B.W.1    Lai, M.2    Hodgkinson, S.3
  • 31
    • 0027450301 scopus 로고
    • Proton nuclear magnetic resonance spectroscopy unambiguously identifies different cell types
    • Urenjak J, Williams SR, Gadian DG, Noble M. Proton nuclear magnetic resonance spectroscopy unambiguously identifies different cell types. J Neurosci 1993;13:981-989
    • (1993) J Neurosci , vol.13 , pp. 981-989
    • Urenjak, J.1    Williams, S.R.2    Gadian, D.G.3    Noble, M.4
  • 32
    • 0028838091 scopus 로고
    • A proliferative adult human oligodendrocyte progenitor
    • Scolding NJ, Rayner PJ, Sussman J, et al. A proliferative adult human oligodendrocyte progenitor. Neuroreport 1995; 6:441-445
    • (1995) Neuroreport , vol.6 , pp. 441-445
    • Scolding, N.J.1    Rayner, P.J.2    Sussman, J.3
  • 33
    • 0028814565 scopus 로고
    • High resolution proton NMR spectroscopy of multiple sclerosis lesions
    • Davies SEC, Newcombe J, Williams SR, et al. High resolution proton NMR spectroscopy of multiple sclerosis lesions. J Neurochem 1995;64:742-748
    • (1995) J Neurochem , vol.64 , pp. 742-748
    • Davies, S.E.C.1    Newcombe, J.2    Williams, S.R.3
  • 34
    • 0027233870 scopus 로고
    • Proton spectroscopy of the brain in HIV infection: Correlation with clinical, immunologic and MR imaging findings
    • Chong WK, Sweeney B, Wilkinson ID, et al. Proton spectroscopy of the brain in HIV infection: correlation with clinical, immunologic and MR imaging findings. Radiology 1993;188: 119-124
    • (1993) Radiology , vol.188 , pp. 119-124
    • Chong, W.K.1    Sweeney, B.2    Wilkinson, I.D.3
  • 35
    • 0026446242 scopus 로고
    • Early time course of N acetyl aspartate, creatinine and phosphocreatine and compounds containing choline in the brain after acute stroke: A proton magnetic resonance study
    • Gideon P, Henricksen O, Sperling B, et al. Early time course of N acetyl aspartate, creatinine and phosphocreatine and compounds containing choline in the brain after acute stroke: a proton magnetic resonance study. Stroke 1992;23:1566-1572
    • (1992) Stroke , vol.23 , pp. 1566-1572
    • Gideon, P.1    Henricksen, O.2    Sperling, B.3
  • 37
    • 0029925782 scopus 로고    scopus 로고
    • Serial gadolinium-enhanced MRI of the brain and spinal cord in early relapsing-remitting multiple sclerosis
    • Thorpe JW, Kidd D, Moseley IF, et al. Serial gadolinium-enhanced MRI of the brain and spinal cord in early relapsing-remitting multiple sclerosis. Neurology 1996;46:373-378
    • (1996) Neurology , vol.46 , pp. 373-378
    • Thorpe, J.W.1    Kidd, D.2    Moseley, I.F.3
  • 38
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B, Matyszak MK, Esiri MM, Perry VH. Axonal damage in acute multiple sclerosis lesions. Brain 1997;120:393-399
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 39
    • 0032576752 scopus 로고    scopus 로고
    • Axonal transection in the lesions of multiple sclerosis
    • Trapp BD, Peterson J, Ransohoff RM, et al. Axonal transection in the lesions of multiple sclerosis. N Engl J Med 1998;338: 278-285
    • (1998) N Engl J Med , vol.338 , pp. 278-285
    • Trapp, B.D.1    Peterson, J.2    Ransohoff, R.M.3
  • 40
    • 0028218020 scopus 로고
    • The role of oligodendrocytes and myelin on axon maturation in the developing rat retinofugal pathway
    • Colello RJ, Pott U, Schwab ME. The role of oligodendrocytes and myelin on axon maturation in the developing rat retinofugal pathway. J Neurosci 1994;14:2594-2605
    • (1994) J Neurosci , vol.14 , pp. 2594-2605
    • Colello, R.J.1    Pott, U.2    Schwab, M.E.3
  • 41
    • 0030901101 scopus 로고    scopus 로고
    • Induction of sodium channel clustering by oligodendrocytes
    • Kaplan MR, Meyer Franke A, Lambert S, et al. Induction of sodium channel clustering by oligodendrocytes. Nature 1997; 386:724-728
    • (1997) Nature , vol.386 , pp. 724-728
    • Kaplan, M.R.1    Meyer Franke, A.2    Lambert, S.3
  • 42
    • 0028867186 scopus 로고
    • Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture
    • Meyer Franke A, Kaplan MR, Pfrieger FW, Barres BA. Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron 1995;15:805-819
    • (1995) Neuron , vol.15 , pp. 805-819
    • Meyer Franke, A.1    Kaplan, M.R.2    Pfrieger, F.W.3    Barres, B.A.4
  • 43
    • 0030773837 scopus 로고    scopus 로고
    • Synaptic efficacy enhanced by glial cells in vitro
    • Pfrieger FW, Barres BA. Synaptic efficacy enhanced by glial cells in vitro. Science 1997;277:1684-1687
    • (1997) Science , vol.277 , pp. 1684-1687
    • Pfrieger, F.W.1    Barres, B.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.