메뉴 건너뛰기




Volumn 108, Issue 8, 2001, Pages 1185-1194

CD4+CD28- costimulation-independent T cells in multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; INTERLEUKIN 12 BETA2 RECEPTOR; INTERLEUKIN 12 RECEPTOR; MYELIN BASIC PROTEIN; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

EID: 0034773579     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200112516     Document Type: Article
Times cited : (232)

References (42)
  • 1
    • 0033786776 scopus 로고    scopus 로고
    • Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand
    • (2000) Nat. Med. , vol.6 , pp. 1167-1175
    • Bielekova, B.1
  • 3
    • 0025370870 scopus 로고
    • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
    • (1990) Nature , vol.346 , pp. 183-187
    • Ota, K.1
  • 4
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • (1994) J. Exp. Med. , vol.179 , pp. 973-984
    • Zhang, J.1
  • 7
    • 0033960291 scopus 로고    scopus 로고
    • Increased numbers of CCR5-interferon-gamma and tumor necrosis factor-alpha-secreting T lymphocytes in multiple sclerosis patients
    • (2000) Ann. Neurol. , vol.47 , pp. 269-273
    • Strunk, T.1
  • 8
    • 0027242269 scopus 로고
    • Adhesion molecule expression on cerebrospinal fluid T lymphocytes: Evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls
    • (1993) Ann. Neurol. , vol.34 , pp. 155-161
    • Svenningsson, A.1
  • 11
    • 0033964373 scopus 로고    scopus 로고
    • Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population
    • (2000) Nat. Med. , vol.6 , pp. 211-214
    • Anderson, D.E.1
  • 15
    • 0028979466 scopus 로고
    • New perspectives of CD28-DB7-mediated T cell costimulation
    • (1995) Immunity , vol.2 , pp. 555-559
    • Bluestone, J.A.1
  • 16
    • 0030176371 scopus 로고    scopus 로고
    • Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement
    • (1996) Immunity , vol.4 , pp. 535-543
    • Linsley, P.S.1
  • 18
    • 0034684648 scopus 로고    scopus 로고
    • T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeca diversity during the initiation of a CD4(+) T cell response in vivo
    • (2000) J. Exp. Med. , vol.192 , pp. 1719-1730
    • Fasso, M.1
  • 19
    • 0032171644 scopus 로고    scopus 로고
    • A very high level of crossreactivity is an essential feature of the T-cell receptor
    • (1998) Immunol. Today , vol.19 , pp. 395-404
    • Mason, D.1
  • 21
    • 0032519421 scopus 로고    scopus 로고
    • Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells
    • (1998) J. Clin. Invest. , vol.101 , pp. 725-730
    • Lovett-Racke, A.E.1
  • 23
    • 0030457897 scopus 로고    scopus 로고
    • CD11b+CD28-CD4+ human T cells: Activation requirements and association with HLA-DR alleles
    • (1996) J. Immunol. , vol.157 , pp. 4771-4780
    • Chapman, A.1
  • 27
    • 0027468174 scopus 로고
    • Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity
    • (1993) Cell , vol.72 , pp. 551-560
    • Goverman, J.1
  • 28
    • 0030267661 scopus 로고    scopus 로고
    • Persistent clonal expansions of peripheral blood CD4+ lymphocytes in chronic inflammatory bowel disease
    • (1996) J. Immunol. , vol.157 , pp. 3183-3191
    • Probert, C.S.1
  • 31
    • 0033577864 scopus 로고    scopus 로고
    • Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells
    • (1999) J. Exp. Med. , vol.189 , pp. 1521-1530
    • Bachmann, M.F.1
  • 32
    • 0034642499 scopus 로고    scopus 로고
    • Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cb1-b
    • (2000) Nature , vol.403 , pp. 211-216
    • Bachmaier, K.1
  • 33
    • 0034642534 scopus 로고    scopus 로고
    • Cb1-b regulates the CD28 dependence of T-cell activation
    • (2000) Nature , vol.403 , pp. 216-220
    • Chiang, Y.J.1
  • 34
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1
  • 35
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulator role of CTLA-4
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1
  • 36
    • 0033560023 scopus 로고    scopus 로고
    • Regulation of interleukin (IL)-12 receptor beta2 subunit expression by endogenous IL-12: A critical step in the differentiation of pathogenic autoreactive T cells
    • (1999) J. Exp. Med. , vol.189 , pp. 969-978
    • Chang, J.T.1    Shevach, E.M.2    Segal, B.M.3
  • 39
    • 0033135564 scopus 로고    scopus 로고
    • CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris
    • (1999) J. Clin. Invest. , vol.103 , pp. 1243-1252
    • Abrams, J.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.