Functional heterogeneity of human memory CD4+ T cell clones primed by pathogens or vaccines

Science

Volumn 347, Issue 6220, 2015, Pages 400-406

  Becattini, Simone ^a,b   Latorre, Daniela ^a   Mele, Federico ^a   Foglierini, Mathilde ^a   De Gregorio, Corinne ^a   Cassotta, Antonino ^a   Fernez, Blanca ^a   Kelderman, Ser ^c   Schumacher, Ton N ^c   Corti, Davide ^a   Lanzavecchia, Antonio ^a,b   Sallusto, Federica ^a  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR; VACCINE; LYMPHOCYTE ANTIGEN RECEPTOR;

CLONE; HETEROGENEITY; MEMORY; PATHOGEN; POLARIZATION; PUBLIC HEALTH; VACCINE;

ARTICLE; CANDIDA ALBICANS; CD4 LYMPHOCYTE COUNT; CELL EXPANSION; CELL HETEROGENEITY; CELL POLARITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CLONE; MYCOBACTERIUM TUBERCULOSIS; PATHOGENESIS; PRIORITY JOURNAL; PROGENY; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; TH2 CELL; AMINO ACID SEQUENCE; CD4+ T LYMPHOCYTE; CELL CLONE; CELL CULTURE; GENETICS; HIGH THROUGHPUT SEQUENCING; HOST PATHOGEN INTERACTION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; CANDIDA ALBICANS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CLONE CELLS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH17 CELLS; TH2 CELLS; VACCINES;

EID: 84921753054     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1260668     Document Type: Article

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