-
1
-
-
16844365788
-
+ regulatory T cells in immunological tolerance to self and non-self
-
+ regulatory T cells in immunological tolerance to self and non-self. Nat. Immunol. 6: 345-352.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
2
-
-
33746356813
-
Human regulatory T cells and their role in autoimmune disease
-
DOI 10.1111/j.0105-2896.2006.00417.x
-
Baecher-Allan, C., and D. A. Hafler. 2006. Human regulatory T cells and their role in autoimmune disease. Immunol. Rev. 212: 203-216. (Pubitemid 44116710)
-
(2006)
Immunological Reviews
, vol.212
, pp. 203-216
-
-
Baecher-Allan, C.1
Hafler, D.A.2
-
3
-
-
33747602533
-
Regulatory T cells in human autoimmune diseases
-
DOI 10.1007/s00281-006-0041-4
-
Torgerson, T. R. 2006. Regulatory T cells in human autoimmune diseases. Springer Semin. Immunopathol. 28: 63-76. (Pubitemid 44267960)
-
(2006)
Springer Seminars in Immunopathology
, vol.28
, Issue.1
, pp. 63-76
-
-
Torgerson, T.R.1
-
4
-
-
33846900430
-
high T regulatory cell function in patients with active systemic lupus erythematosus
-
high T regulatory cell function in patients with active systemic lupus erythematosus. J. Immunol. 178: 2579-2588.
-
(2007)
J. Immunol.
, vol.178
, pp. 2579-2588
-
-
Valencia, X.1
Yarboro, C.2
Illei, G.3
Lipsky, P.E.4
-
5
-
-
2442484053
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses
-
+ regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22: 531-562.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
7
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
DOI 10.1126/science.1079490
-
Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061. (Pubitemid 36222930)
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
8
-
-
33745817085
-
+ Treg cells
-
+ Treg cells. J. Exp. Med. 203: 1701-1711.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
Gottlieb, P.A.7
Kapranov, P.8
Gingeras, T.R.9
Fazekas De St Groth, B.10
-
9
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
-
DOI 10.1084/jem.20060468
-
Seddiki, N., B. Santner-Nanan, J. Martinson, J. Zaunders, S. Sasson, A. Landay, M. Solomon, W. Selby, S. I. Alexander, R. Nanan, et al. 2006. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J. Exp. Med. 203: 1693-1700. (Pubitemid 44036275)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.7
, pp. 1693-1700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
Zaunders, J.4
Sasson, S.5
Landay, A.6
Solomon, M.7
Selby, W.8
Alexander, S.I.9
Nanan, R.10
Kelleher, A.11
De St Groth, B.F.12
-
11
-
-
22144466887
-
+ Tregs
-
DOI 10.1172/JCI23963
-
Valmori, D., A. Merlo, N. E. Souleimanian, C. S. Hesdorffer, and M. Ayyoub. 2005. A peripheral circulating compartment of natural naive CD4 Tregs. J. Clin. Invest. 115: 1953-1962. (Pubitemid 40979735)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.7
, pp. 1953-1962
-
-
Valmori, D.1
Merlo, A.2
Souleimanian, N.E.3
Hesdorffer, C.S.4
Ayyoub, M.5
-
12
-
-
33751175422
-
Naive regulatory T cells: A novel subpopulation defined by resistance toward CD95L-mediated cell death
-
Fritzsching, B., N. Oberle, E. Pauly, R. Geffers, J. Buer, J. Poschl, P. Krammer, O. Linderkamp, and E. Suri-Payer. 2006. Naive regulatory T cells: a novel subpopulation defined by resistance toward CD95L-mediated cell death. Blood 108: 3371-3378.
-
(2006)
Blood
, vol.108
, pp. 3371-3378
-
-
Fritzsching, B.1
Oberle, N.2
Pauly, E.3
Geffers, R.4
Buer, J.5
Poschl, J.6
Krammer, P.7
Linderkamp, O.8
Suri-Payer, E.9
-
13
-
-
33645510596
-
+ regulatory T cells in adult life
-
+ regulatory T cells in adult life. Blood 107: 2830-2838.
-
(2006)
Blood
, vol.107
, pp. 2830-2838
-
-
Seddiki, N.1
Santner-Nanan, B.2
Tangye, S.G.3
Alexander, S.I.4
Solomon, M.5
Lee, S.6
Nanan, R.7
Fazekas De St Groth, B.8
-
14
-
-
20444497416
-
high regulatory T cells increases with age
-
high regulatory T cells increases with age. Clin. Exp. Immunol. 140: 540-546.
-
(2005)
Clin. Exp. Immunol.
, vol.140
, pp. 540-546
-
-
Gregg, R.1
Smith, C.M.2
Clark, F.J.3
Dunnion, D.4
Khan, N.5
Chakraverty, R.6
Nayak, L.7
Moss, P.A.8
-
15
-
-
34447629515
-
Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration
-
DOI 10.1016/j.jneuroim.2007.05.011, PII S0165572807001749
-
Rosenkranz, D., S. Weyer, E. Tolosa, A. Gaenslen, D. Berg, T. Leyhe, T. Gasser, and L. Stoltze. 2007. Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration. J. Neuroimmunol. 188: 117-127. (Pubitemid 47095016)
-
(2007)
Journal of Neuroimmunology
, vol.188
, Issue.1-2
, pp. 117-127
-
-
Rosenkranz, D.1
Weyer, S.2
Tolosa, E.3
Gaenslen, A.4
Berg, D.5
Leyhe, T.6
Gasser, T.7
Stoltze, L.8
-
16
-
-
33748296240
-
+ regulatory T cells are derived by rapid turnover of memory populations in vivo
-
+ regulatory T cells are derived by rapid turnover of memory populations in vivo. J. Clin. Invest. 116: 2423-2433.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2423-2433
-
-
Vukmanovic-Stejic, M.1
Zhang, Y.2
Cook, J.E.3
Fletcher, J.M.4
McQuaid, A.5
Masters, J.E.6
Rustin, M.H.7
Taams, L.S.8
Beverley, P.C.9
Macallan, D.C.10
Akbar, A.N.11
-
18
-
-
27944499757
-
high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis
-
high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis. Eur. J. Immunol. 35: 3343-3352.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 3343-3352
-
-
Haas, J.1
Hug, A.2
Viehover, A.3
Fritzsching, B.4
Falk, C.S.5
Filser, A.6
Vetter, T.7
Milkova, L.8
Korporal, M.9
Fritz, B.10
-
19
-
-
33744904725
-
+ regulatory T-cell function and FOXP3 expression
-
+ regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 83: 1432-1446.
-
(2006)
J. Neurosci. Res.
, vol.83
, pp. 1432-1446
-
-
Venken, K.1
Hellings, N.2
Hensen, K.3
Rummens, J.L.4
Medaer, R.5
D'Hooghe, M.B.6
Dubois, B.7
Raus, J.8
Stinissen, P.9
-
20
-
-
23744515175
-
Decreased FOXP3 levels in multiple sclerosis patients
-
DOI 10.1002/jnr.20522
-
Huan, J., N. Culbertson, L. Spencer, R. Bartholomew, G. G. Burrows, Y. K. Chou, D. Bourdette, S. F. Ziegler, H. Offner, and A. A. Vandenbark. 2005. Decreased FOXP3 levels in multiple sclerosis patients. J. Neurosci. Res. 81: 45-52. (Pubitemid 41139109)
-
(2005)
Journal of Neuroscience Research
, vol.81
, Issue.1
, pp. 45-52
-
-
Huan, J.1
Culbertson, N.2
Spencer, L.3
Bartholomew, R.4
Burrows, G.G.5
Chou, Y.K.6
Bourdette, D.7
Ziegler, S.F.8
Offner, H.9
Vandenbark, A.A.10
-
21
-
-
37149003363
-
high regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level
-
high regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level. Immunology 123: 79-89.
-
(2008)
Immunology
, vol.123
, pp. 79-89
-
-
Venken, K.1
Hellings, N.2
Thewissen, M.3
Somers, V.4
Hensen, K.5
Rummens, J.L.6
Medaer, R.7
Hupperts, R.8
Stinissen, P.9
-
22
-
-
0034955141
-
Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis
-
DOI 10.1002/ana.1032
-
McDonald, W. I., A. Compston, G. Edan, D. Goodkin, H. P. Hartung, F. D. Lublin, H. F. McFarland, D. W. Paty, C. H. Polman, S. C. Reingold, et al. 2001. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann. Neurol. 50: 121-127. (Pubitemid 32591472)
-
(2001)
Annals of Neurology
, vol.50
, Issue.1
, pp. 121-127
-
-
Buckley, C.1
Douek, D.2
Newsom-Davis, J.3
Vincent, A.4
Willcox, N.5
-
24
-
-
34247108103
-
Analyses of immunosenescent markers in patients with autoimmune disease
-
DOI 10.1016/j.clim.2007.01.005, PII S1521661607000083
-
Thewissen, M., V. Somers, K. Venken, L. Linsen, P. Van Paassen, P. Geusens, J. Damoiseaux, and P. Stinissen. 2007. Analyses of immunosenescent markers in patients with autoimmune disease. Clin. Immunol. 123: 209-218. (Pubitemid 46590073)
-
(2007)
Clinical Immunology
, vol.123
, Issue.2
, pp. 209-218
-
-
Thewissen, M.1
Somers, V.2
Venken, K.3
Linsen, L.4
Van Paassen, P.5
Geusens, P.6
Damoiseaux, J.7
Stinissen, P.8
-
26
-
-
0030017526
-
The complete 685-kilobase DNA sequence of the human β T cell receptor locus
-
Rowen, L., B. F. Koop, and L. Hood. 1996. The complete 685-kilobase DNA sequence of the human β T cell receptor locus. Science 272: 1755-1762. (Pubitemid 26256389)
-
(1996)
Science
, vol.272
, Issue.5269
, pp. 1755-1762
-
-
Rowen, L.1
Koop, B.F.2
Hood, L.3
-
27
-
-
23944490475
-
Memory T cell homeostasis and senescence during aging
-
DOI 10.1016/j.coi.2005.07.019, PII S095279150500124X
-
Akbar, A. N., and J. M. Fletcher. 2005. Memory T cell homeostasis and senescence during aging. Curr. Opin. Immunol. 17: 480-485. (Pubitemid 41207950)
-
(2005)
Current Opinion in Immunology
, vol.17
, Issue.5
, pp. 480-485
-
-
Akbar, A.N.1
Fletcher, J.M.2
-
28
-
-
0037128660
-
Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood
-
DOI 10.1084/jem.20011756
-
Kimmig, S., G. K. Przybylski, C. A. Schmidt, K. Laurisch, B. Mowes, A. Radbruch, and A. Thiel. 2002. Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195: 789-794. (Pubitemid 34259723)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.6
, pp. 789-794
-
-
Kimmig, S.1
Przybylski, G.K.2
Schmidt, C.A.3
Laurisch, K.4
Mowes, B.5
Radbruch, A.6
Thiel, A.7
-
29
-
-
33845873044
-
+ regulatory T-cell function: An ex vivo and in vitro longitudinal study in relapsing-remitting multiple sclerosis
-
DOI 10.1016/j.jneuroim.2006.09.012, PII S0165572806003808
-
de Andres, C., C. Aristimuno, V. de Las Heras, M. L. Martinez-Gines, M. Bartolome, R. Arroyo, J. Navarro, S. Gimenez-Roldan, E. Fernandez-Cruz, and S. Sanchez-Ramon. 2007. Interferon β-1a therapy enhances CD4β regulatory T-cell function: an ex vivo and in vitro longitudinal study in relapsing-remitting multiple sclerosis. J. Neuroimmunol. 182: 204-211. (Pubitemid 46026708)
-
(2007)
Journal of Neuroimmunology
, vol.182
, Issue.1-2
, pp. 204-211
-
-
De Andres, C.1
Aristimuno, C.2
De Las Heras, V.3
Martinez-Gines, M.L.4
Bartolome, M.5
Arroyo, R.6
Navarro, J.7
Gimenez-Roldan, S.8
Fernandez-Cruz, E.9
Sanchez-Ramon, S.10
-
31
-
-
0036284229
-
+ T cells in thymus, cord, and adult blood
-
+ T cells in thymus, cord, and adult blood. Immunology 106: 190-199.
-
(2002)
Immunology
, vol.106
, pp. 190-199
-
-
Wing, K.1
Ekmark, A.2
Karlsson, H.3
Rudin, A.4
Suri-Payer, E.5
-
32
-
-
0031573665
-
+ stage, before the onset of functional maturation
-
+ stage, before the onset of functional maturation. J. Immunol. 159: 5973-5983.
-
(1997)
J. Immunol.
, vol.159
, pp. 5973-5983
-
-
Vanhecke, D.1
Verhasselt, B.2
De Smedt, M.3
Leclercq, G.4
Plum, J.5
Vandekerckhove, B.6
-
33
-
-
0035161658
-
T cell receptor excision circles as markers for recent thymic emigrants: Basic aspects, technical approach, and guidelines for interpretation
-
DOI 10.1007/s001090100271
-
Hazenberg, M. D., M. C. Verschuren, D. Hamann, F. Miedema, and J. J. van Dongen. 2001. T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation. J. Mol. Med. 79: 631-640. (Pubitemid 33071151)
-
(2001)
Journal of Molecular Medicine
, vol.79
, Issue.11
, pp. 631-640
-
-
Hazenberg, M.D.1
Verschuren, M.C.2
Hamann, D.3
Miedema, F.4
Dongen, J.J.5
-
34
-
-
33644866342
-
Altered naive CD4 and CD8 T cell homeostasis in patients with relapsing-remitting multiple sclerosis: Thymic versus peripheral (non-thymic) mechanisms
-
Duszczyszyn, D. A., J. D. Beck, J. Antel, A. Bar-Or, Y. Lapierre, V. Gadag, and D. G. Haegert. 2006. Altered naive CD4 and CD8 T cell homeostasis in patients with relapsing-remitting multiple sclerosis: thymic versus peripheral (non-thymic) mechanisms. Clin. Exp. Immunol. 143: 305-313.
-
(2006)
Clin. Exp. Immunol.
, vol.143
, pp. 305-313
-
-
Duszczyszyn, D.A.1
Beck, J.D.2
Antel, J.3
Bar-Or, A.4
Lapierre, Y.5
Gadag, V.6
Haegert, D.G.7
-
35
-
-
34548721641
-
Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis
-
Haas, J., B. Fritzsching, P. Trubswetter, M. Korporal, L. Milkova, B. Fritz, D. Vobis, P. H. Krammer, E. Suri-Payer, and B. Wildemann. 2007. Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis. J. Immunol. 179: 1322-1330.
-
(2007)
J. Immunol.
, vol.179
, pp. 1322-1330
-
-
Haas, J.1
Fritzsching, B.2
Trubswetter, P.3
Korporal, M.4
Milkova, L.5
Fritz, B.6
Vobis, D.7
Krammer, P.H.8
Suri-Payer, E.9
Wildemann, B.10
-
36
-
-
0037530472
-
Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis
-
Hug, A., M. Korporal, I. Schroder, J. Haas, K. Glatz, B. Storch-Hagenlocher, and B. Wildemann. 2003. Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis. J. Immunol. 171: 432-437. (Pubitemid 36745317)
-
(2003)
Journal of Immunology
, vol.171
, Issue.1
, pp. 432-437
-
-
Hug, A.1
Korporal, M.2
Schroder, I.3
Haas, J.4
Glatz, K.5
Storch-Hagenlocher, B.6
Wildemann, B.7
-
37
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
DOI 10.1056/NEJMoa073493
-
Hafler, D. A., A. Compston, S. Sawcer, E. S. Lander, M. J. Daly, P. L. De Jager, P. I. de Bakker, S. B. Gabriel, D. B. Mirel, A. J. Ivinson, et al. 2007. Risk alleles for multiple sclerosis identified by a genomewide study. N. Engl. J. Med. 357: 851-862. (Pubitemid 47347319)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.9
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
De Bakker, P.I.W.7
Gabriel, S.B.8
Mirel, D.B.9
Ivinson, A.J.10
Pericak-Vance, M.A.11
Gregory, S.G.12
Rioux, J.D.13
McCauley, J.L.14
Haines, J.L.15
Barcellos, L.F.16
Cree, B.17
Oksenberg, J.R.18
Hauser, S.L.19
-
38
-
-
34147128572
-
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
-
DOI 10.1038/nm1564, PII NM1564
-
Korn, T., J. Reddy, W. Gao, E. Bettelli, A. Awasthi, T. R. Petersen, B. T. Backstrom, R. A. Sobel, K. W. Wucherpfennig, T. B. Strom, et al. 2007. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat. Med. 13: 423-431. (Pubitemid 46559831)
-
(2007)
Nature Medicine
, vol.13
, Issue.4
, pp. 423-431
-
-
Korn, T.1
Reddy, J.2
Gao, W.3
Bettelli, E.4
Awasthi, A.5
Petersen, T.R.6
Backstrom, B.T.7
Sobel, R.A.8
Wucherpfennig, K.W.9
Strom, T.B.10
Oukka, M.11
Kuchroo, V.K.12
-
40
-
-
0032749804
-
Disease steps in multiple sclerosis: A longitudinal study comparing Disease Steps and EDSS to evaluate disease progression
-
Hohol, M. J., E. J. Orav, and H. L. Weiner. 1999. Disease steps in multiple sclerosis: a longitudinal study comparing disease steps and EDSS to evaluate disease progression. Mult. Scler. 5: 349-354. (Pubitemid 29505050)
-
(1999)
Multiple Sclerosis
, vol.5
, Issue.5
, pp. 349-354
-
-
Hohol, M.J.1
Orav, E.J.2
Weiner, H.L.3
-
41
-
-
33644974688
-
Secondary progressive multiple sclerosis: Current knowledge and future challenges
-
Rovaris, M., C. Confavreux, R. Furlan, L. Kappos, G. Comi, and M. Filippi. 2006. Secondary progressive multiple sclerosis: current knowledge and future challenges. Lancet Neurol. 5: 343-354.
-
(2006)
Lancet Neurol.
, vol.5
, pp. 343-354
-
-
Rovaris, M.1
Confavreux, C.2
Furlan, R.3
Kappos, L.4
Comi, G.5
Filippi, M.6
-
42
-
-
17644396349
-
Immunology of multiple sclerosis
-
DOI 10.1146/annurev.immunol.23.021704.115707
-
Sospedra, M., and R. Martin. 2005. Immunology of multiple sclerosis. Annu. Rev. Immunol. 23: 683-747. (Pubitemid 40563183)
-
(2005)
Annual Review of Immunology
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
43
-
-
21244465055
-
+ regulatory T cells are highly susceptible to CD95 ligand- But not to TCR-mediated cell death
-
+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death. J. Immunol. 175: 32-36.
-
(2005)
J. Immunol.
, vol.175
, pp. 32-36
-
-
Fritzsching, B.1
Oberle, N.2
Eberhardt, N.3
Quick, S.4
Haas, J.5
Wildemann, B.6
Krammer, P.H.7
Suri-Payer, E.8
-
45
-
-
0035186416
-
Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells
-
DOI 10.1034/j.1600-065X.2001.1820117.x
-
Weiner, H. L. 2001. Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells. Immunol. Rev. 182: 207-214. (Pubitemid 33070220)
-
(2001)
Immunological Reviews
, vol.182
, pp. 207-214
-
-
Weiner, H.L.1
-
46
-
-
32644471889
-
Tr1 cells: From discovery to their clinical application
-
DOI 10.1016/j.smim.2006.01.007, PII S104453230600008X, Regulatory T Cells
-
Battaglia, M., S. Gregori, R. Bacchetta, and M. G. Roncarolo. 2006. Tr1 cells: from discovery to their clinical application. Semin. Immunol. 18: 120-127. (Pubitemid 43248740)
-
(2006)
Seminars in Immunology
, vol.18
, Issue.2
, pp. 120-127
-
-
Battaglia, M.1
Gregori, S.2
Bacchetta, R.3
Roncarolo, M.-G.4
-
47
-
-
33645778289
-
MHC class II expression identifies functionally distinct human regulatory T cells
-
Baecher-Allan, C., E. Wolf, and D. A. Hafler. 2006. MHC class II expression identifies functionally distinct human regulatory T cells. J. Immunol. 176: 4622-4631.
-
(2006)
J. Immunol.
, vol.176
, pp. 4622-4631
-
-
Baecher-Allan, C.1
Wolf, E.2
Hafler, D.A.3
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