Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

Nature Medicine

Volumn 13, Issue 10, 2007, Pages 1173-1175

  Kebir, Hania ^a   Kreymborg, Katharina ^b   Ifergan, Igal ^a   Dodelet Devillers, Aurore ^a   Cayrol, Romain ^a   Bernard, Monique ^a   Giuliani, Fabrizio ^c   Arbour, Nathalie ^a   Becher, Burkhard ^b   Prat, Alexandre ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME B; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN RECEPTOR; GRANZYME; INTERLEUKIN 22 RECEPTOR; INTERLEUKIN-22 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CD4+ T LYMPHOCYTE; CELL MIGRATION; CENTRAL NERVOUS SYSTEM DISEASE; CENTRAL NERVOUS SYSTEM INFLAMMATION; CONTROLLED STUDY; ENDOTHELIUM CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MULTIPLE SCLEROSIS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; CASE CONTROL STUDY; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CELL MOTION; CENTRAL NERVOUS SYSTEM; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; HELPER CELL; HUMAN; IMMUNOLOGY; INFLAMMATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TIGHT JUNCTION; VASCULAR ENDOTHELIUM;

BLOOD-BRAIN BARRIER; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CELL MEMBRANE PERMEABILITY; CELL MOVEMENT; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GRANZYMES; HUMANS; INFLAMMATION; INTERLEUKIN-17; MULTIPLE SCLEROSIS; RECEPTORS, INTERLEUKIN; T-LYMPHOCYTES, HELPER-INDUCER; TIGHT JUNCTIONS;

EID: 34948909646     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1651     Document Type: Article

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