Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation

Annual Review of Analytical Chemistry

Volumn 9, Issue , 2016, Pages 521-545

  Sheynkman, Gloria M ^a,b,c   Shortreed, Michael R ^c   Cesnik, Anthony J ^c   Smith, Lloyd M ^c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Alternative splicing; Customized protein databases; Genetic variation; Isoforms; Novel splice junction; Polymorphism; Proteoform; Proteomics; Sample specific databases; Single amino acid variant

Indexed keywords

DATABASE SYSTEMS; DNA SEQUENCES; GENE ENCODING; GENES; MASS SPECTROMETRY; MOLECULAR BIOLOGY; POLYMORPHISM; SEARCH ENGINES; SPECTROMETRY;

ALTERNATIVE SPLICING; GENETIC VARIATION; ISOFORMS; PROTEIN DATABASE; PROTEOFORM; PROTEOMICS; SINGLE AMINO ACID VARIANT; SPLICE JUNCTIONS;

PROTEINS;

PROTEIN;

CHEMISTRY; GENETIC VARIATION; GENETICS; HUMAN; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PROTEOGENOMICS;

BASE SEQUENCE; GENETIC VARIATION; HUMANS; MASS SPECTROMETRY; PROTEINS; PROTEOGENOMICS;

EID: 84975484700     PISSN: 19361327     EISSN: 19361335     Source Type: Book Series    
DOI: 10.1146/annurev-anchem-071015-041722     Document Type: Review

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