Monitoring M-proteins in patients with multiple myeloma using heavy-chain variable region clonotypic peptides and LC-MS/MS

Journal of Proteome Research

Volumn 13, Issue 4, 2014, Pages 1905-1910

  Barnidge, David R ^a   Tschumper, Renee C ^b   Theis, Jason D ^a   Snyder, Melissa R ^a   Jelinek, Diane F ^b   Katzmann, Jerry A ^a   Dispenzieri, Angela ^a   Murray, David L ^a  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

biomarker; clonotypic; digest; individualized; M protein; mass spectrometry; multiple myeloma; peptide; proteotypic; specificity; SRM; variable region

Indexed keywords

BIOLOGICAL MARKER; CLONOTYPIC PEPTIDE; IMMUNOGLOBULIN G; M PROTEIN; PEPTIDE; UNCLASSIFIED DRUG; IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN VARIABLE REGION; M-PROTEINS (MYELOMA);

ARTICLE; CELL CLONE; CLINICAL ARTICLE; CONTROLLED STUDY; GENE SEQUENCE; HEAVY CHAIN; HUMAN; LIQUID CHROMATOGRAPHY; MULTIPLE MYELOMA; PLASMA CELL; PRIORITY JOURNAL; PROTEIN DATABASE; TANDEM MASS SPECTROMETRY; BLOOD; CHEMISTRY; IMMUNOGLOBULIN VARIABLE REGION; PROCEDURES; PROTEOMICS;

CHROMATOGRAPHY, LIQUID; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOGLOBULINS; MULTIPLE MYELOMA; PEPTIDES; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84898744545     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5000544     Document Type: Article

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