메뉴 건너뛰기




Volumn 15, Issue 3, 2014, Pages 193-204

Emerging evidence for functional peptides encoded by short open reading frames

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; HUMANS; OPEN READING FRAMES; PEPTIDES; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; RNA, UNTRANSLATED;

EID: 84894380391     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg3520     Document Type: Review
Times cited : (434)

References (120)
  • 1
    • 79959421469 scopus 로고    scopus 로고
    • Identification of prokaryotic small proteins using a comparative genomic approach
    • Samayoa, J., Yildiz, F. H. & Karplus, K. Identification of prokaryotic small proteins using a comparative genomic approach. Bioinformatics 27, 1765-1771 (2011).
    • (2011) Bioinformatics , vol.27 , pp. 1765-1771
    • Samayoa, J.1    Yildiz, F.H.2    Karplus, K.3
  • 3
    • 0035851192 scopus 로고    scopus 로고
    • Polyamine regulation of ribosome pausing at the upstream open reading frame of S-adenosylmethionine decarboxylase
    • Law, G. L., Raney, A., Heusner, C. & Morris, D. R. Polyamine regulation of ribosome pausing at the upstream open reading frame of S-adenosylmethionine decarboxylase. J. Biol. Chem. 276, 38036-38043 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 38036-38043
    • Law, G.L.1    Raney, A.2    Heusner, C.3    Morris, D.R.4
  • 4
    • 33751072654 scopus 로고    scopus 로고
    • The Arabidopsis unannotated secreted peptide database, a resource for plant peptidomics
    • Lease, K. A. & Walker, J. C. The Arabidopsis unannotated secreted peptide database, a resource for plant peptidomics. Plant Physiol. 142, 831-838 (2006).
    • (2006) Plant Physiol. , vol.142 , pp. 831-838
    • Lease, K.A.1    Walker, J.C.2
  • 5
    • 41449119243 scopus 로고    scopus 로고
    • Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species
    • Hayden, C. & Bosco, G. Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. BMC Genomics 9, 61 (2008).
    • (2008) BMC Genomics , vol.9 , pp. 61
    • Hayden, C.1    Bosco, G.2
  • 6
    • 79953331944 scopus 로고    scopus 로고
    • Discovery and annotation of small proteins using genomics, proteomics, and computational approaches
    • Yang, X. et al. Discovery and annotation of small proteins using genomics, proteomics, and computational approaches. Genome Res. 21, 634-641 (2011).
    • (2011) Genome Res. , vol.21 , pp. 634-641
    • Yang, X.1
  • 7
    • 77954818578 scopus 로고    scopus 로고
    • An overview of the current status of eukaryote gene prediction strategies
    • Sleator, R. D. An overview of the current status of eukaryote gene prediction strategies. Gene 461, 1-4 (2010).
    • (2010) Gene , vol.461 , pp. 1-4
    • Sleator, R.D.1
  • 8
    • 2942521197 scopus 로고    scopus 로고
    • Recent advances in gene structure prediction
    • Brent, M. R. & Guigó, R. Recent advances in gene structure prediction. Curr. Opin. Struct. Biol. 14, 264-272 (2004).
    • (2004) Curr. Opin. Struct. Biol. , vol.14 , pp. 264-272
    • Brent, M.R.1    Guigó, R.2
  • 9
    • 0042880980 scopus 로고    scopus 로고
    • Vertebrate gene predictions and the problem of large genes
    • Wang, J. et al. Vertebrate gene predictions and the problem of large genes. Nature Rev. Genet. 4, 741-749 (2003).
    • (2003) Nature Rev. Genet. , vol.4 , pp. 741-749
    • Wang, J.1
  • 10
    • 34248202149 scopus 로고    scopus 로고
    • A large number of novel coding small open reading frames in the intergenic regions of the Arabidopsis thaliana genome are transcribed and/or under purifying selection
    • Hanada, K., Zhang, X., Borevitz, J. O., Li, W.-H. & Shiu, S.-H. A large number of novel coding small open reading frames in the intergenic regions of the Arabidopsis thaliana genome are transcribed and/or under purifying selection. Genome Res. 17, 632-640 (2007).
    • (2007) Genome Res. , vol.17 , pp. 632-640
    • Hanada, K.1    Zhang, X.2    Borevitz, J.O.3    Li, W.-H.4    Shiu, S.-H.5
  • 11
    • 80052208938 scopus 로고    scopus 로고
    • Small open reading frames: Current prediction techniques and future prospect
    • Cheng, H. et al. Small open reading frames: current prediction techniques and future prospect. Curr. Protein Pept. Sci. 12, 503-507 (2011).
    • (2011) Curr. Protein Pept. Sci. , vol.12 , pp. 503-507
    • Cheng, H.1
  • 12
    • 0030960992 scopus 로고    scopus 로고
    • Small open reading frames: Beautiful needles in the haystack
    • Basrai, M. A., Hieter, P. & Boeke, J. D. Small open reading frames: beautiful needles in the haystack. Genome Res. 7, 768-771 (1997).
    • (1997) Genome Res. , vol.7 , pp. 768-771
    • Basrai, M.A.1    Hieter, P.2    Boeke, J.D.3
  • 13
    • 0030768930 scopus 로고    scopus 로고
    • Computational methods for the identification of genes in vertebrate genomic sequences
    • Claverie, J.-M. Computational methods for the identification of genes in vertebrate genomic sequences. Hum. Mol. Genet. 6, 1735-1744 (1997).
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1735-1744
    • Claverie, J.-M.1
  • 14
    • 33646483032 scopus 로고    scopus 로고
    • The abundance of short proteins in the mammalian proteome
    • Frith, M. C. et al. The abundance of short proteins in the mammalian proteome. PLoS Genet. 2, e52 (2006).
    • (2006) PLoS Genet. , vol.2
    • Frith, M.C.1
  • 15
    • 44249122651 scopus 로고    scopus 로고
    • Lilliputians get into the limelight: Novel class of small peptide genes in morphogenesis
    • Hashimoto, Y., Kondo, T. & Kageyama, Y. Lilliputians get into the limelight: novel class of small peptide genes in morphogenesis. Dev. Growth Differ. 50, S269-S276 (2008).
    • (2008) Dev. Growth Differ. , vol.50
    • Hashimoto, Y.1    Kondo, T.2    Kageyama, Y.3
  • 16
    • 33644641676 scopus 로고    scopus 로고
    • Functional genomics of genes with small open reading frames (sORFs) in S. Cerevisiae
    • Kastenmayer, J. P. et al. Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res. 16, 365-373 (2006).
    • (2006) Genome Res. , vol.16 , pp. 365-373
    • Kastenmayer, J.P.1
  • 17
    • 33745584056 scopus 로고    scopus 로고
    • SwePep, a database designed for endogenous peptides and mass spectrometry
    • Fälth, M. et al. SwePep, a database designed for endogenous peptides and mass spectrometry. Mol. Cell. Proteom. 5, 998-1005 (2006).
    • (2006) Mol. Cell. Proteom. , vol.5 , pp. 998-1005
    • Fälth, M.1
  • 18
    • 84871325792 scopus 로고    scopus 로고
    • Peptidomic discovery of short open reading frame-encoded peptides in human cells
    • Slavoff, S. A. et al. Peptidomic discovery of short open reading frame-encoded peptides in human cells. Nature Chem. Biol. 9, 59-64 (2013).
    • (2013) Nature Chem. Biol. , vol.9 , pp. 59-64
    • Slavoff, S.A.1
  • 19
    • 84868315457 scopus 로고    scopus 로고
    • Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
    • Fritsch, C. et al. Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting. Genome Res. 22, 2208-2218 (2012).
    • (2012) Genome Res. , vol.22 , pp. 2208-2218
    • Fritsch, C.1
  • 20
    • 81055155799 scopus 로고    scopus 로고
    • Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes
    • Ingolia, N. T., Lareau, L. F. & Weissman, J. S. Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell 147, 789-802 (2011).
    • (2011) Cell , vol.147 , pp. 789-802
    • Ingolia, N.T.1    Lareau, L.F.2    Weissman, J.S.3
  • 21
    • 84866267681 scopus 로고    scopus 로고
    • Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution
    • Lee, S. et al. Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution. Proc. Natl Acad. Sci. 109, E2424-E2432 (2012).
    • (2012) Proc. Natl Acad. Sci. , vol.109
    • Lee, S.1
  • 22
    • 84865535621 scopus 로고    scopus 로고
    • BAIUCAS: A novel BLAST-based algorithm for the identification of upstream open reading frames with conserved amino acid sequences and its application to the Arabidopsis thaliana genome
    • Takahashi, H., Takahashi, A., Naito, S. & Onouchi, H. BAIUCAS: a novel BLAST-based algorithm for the identification of upstream open reading frames with conserved amino acid sequences and its application to the Arabidopsis thaliana genome. Bioinformatics 28, 2231-2241 (2012).
    • (2012) Bioinformatics , vol.28 , pp. 2231-2241
    • Takahashi, H.1    Takahashi, A.2    Naito, S.3    Onouchi, H.4
  • 23
    • 58549101102 scopus 로고    scopus 로고
    • Discovery and revision of Arabidopsis genes by proteogenomics
    • Castellana, N. E. et al. Discovery and revision of Arabidopsis genes by proteogenomics. Proc. Natl Acad. Sci. 105, 21034-21038 (2008).
    • (2008) Proc. Natl Acad. Sci. , vol.105 , pp. 21034-21038
    • Castellana, N.E.1
  • 24
    • 84881529829 scopus 로고    scopus 로고
    • Direct detection of alternative open reading frames translation products in human significantly expands the proteome
    • Vanderperre, B. et al. Direct detection of alternative open reading frames translation products in human significantly expands the proteome. PLoS ONE 8, e70698 (2013).
    • (2013) PLoS ONE , vol.8
    • Vanderperre, B.1
  • 25
    • 84879936964 scopus 로고    scopus 로고
    • Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near-cognate translation initiation events
    • Menschaert, G. et al. Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near-cognate translation initiation events. Mol. Cell. Proteom. 12, 1780-1790 (2013).
    • (2013) Mol. Cell. Proteom. , vol.12 , pp. 1780-1790
    • Menschaert, G.1
  • 26
    • 77949511569 scopus 로고    scopus 로고
    • SORF finder: A program package to identify small open reading frames with high coding potential
    • Hanada, K. et al. sORF finder: a program package to identify small open reading frames with high coding potential. Bioinformatics 26, 399-400 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 399-400
    • Hanada, K.1
  • 27
    • 84862250906 scopus 로고    scopus 로고
    • HAltORF: A database of predicted out-of-frame alternative open reading frames in human
    • Vanderperre, B., Lucier, J. F. & Roucou, X. HAltORF: a database of predicted out-of-frame alternative open reading frames in human. Database (Oxford) 2012, bas025 (2012).
    • (2012) Database (Oxford) , vol.2012
    • Vanderperre, B.1    Lucier, J.F.2    Roucou, X.3
  • 28
    • 84893163535 scopus 로고    scopus 로고
    • UPEPperoni: An online tool for upstream open reading frame location and analysis of transcript conservation
    • Skarshewski, A. et al. uPEPperoni: an online tool for upstream open reading frame location and analysis of transcript conservation. BMC Bioinformatics http://dx.doi.org/10.1186/1471-2105-15-36 (2014).
    • (2014) BMC Bioinformatics
    • Skarshewski, A.1
  • 29
    • 0036720020 scopus 로고    scopus 로고
    • The Ka/Ks ratio: Diagnosing the form of sequence evolution
    • Hurst, L. D. The Ka/Ks ratio: diagnosing the form of sequence evolution. Trends Genet. 18, 486-487 (2002).
    • (2002) Trends Genet. , vol.18 , pp. 486-487
    • Hurst, L.D.1
  • 30
    • 27644556090 scopus 로고    scopus 로고
    • Identification and characterization of upstream open reading frames (uORF) in the 5? Untranslated regions (UTR) of genes in Saccharomyces cerevisiae
    • Zhang, Z. & Dietrich, F. Identification and characterization of upstream open reading frames (uORF) in the 5? Untranslated regions (UTR) of genes in Saccharomyces cerevisiae. Curr. Genet. 48, 77-87 (2005).
    • (2005) Curr. Genet. , vol.48 , pp. 77-87
    • Zhang, Z.1    Dietrich, F.2
  • 32
    • 37648999313 scopus 로고    scopus 로고
    • Distinguishing protein-coding and noncoding genes in the human genome
    • Clamp, M. et al. Distinguishing protein-coding and noncoding genes in the human genome. Proc. Natl Acad. Sci. 104, 19428-19433 (2007).
    • (2007) Proc. Natl Acad. Sci. , vol.104 , pp. 19428-19433
    • Clamp, M.1
  • 33
    • 0023665902 scopus 로고
    • An analysis of 5?-noncoding sequences from 699 vertebrate messenger RNAs
    • Kozak, M. An analysis of 5?-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15, 8125-8148 (1987).
    • (1987) Nucleic Acids Res. , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 34
    • 0032426005 scopus 로고    scopus 로고
    • Comparative DNA analysis across diverse genomes
    • Karlin, S., Campbell, A. M. & Mrázek, J. Comparative DNA analysis across diverse genomes. Annu. Rev. Genet. 32, 185-225 (1998).
    • (1998) Annu. Rev. Genet. , vol.32 , pp. 185-225
    • Karlin, S.1    Campbell, A.M.2    Mrázek, J.3
  • 35
    • 9144257886 scopus 로고    scopus 로고
    • The Pfam protein families database
    • Bateman, A. et al. The Pfam protein families database. Nucleic Acids Res. 32, D138-D141 (2004).
    • (2004) Nucleic Acids Res. , vol.32
    • Bateman, A.1
  • 36
    • 36148976155 scopus 로고    scopus 로고
    • Identification of novel conserved peptide uORF homology groups in Arabidopsis and rice reveals ancient eukaryotic origin of select groups and preferential association with transcription factor-encoding genes
    • Hayden, C. & Jorgensen, R. Identification of novel conserved peptide uORF homology groups in Arabidopsis and rice reveals ancient eukaryotic origin of select groups and preferential association with transcription factor-encoding genes. BMC Biol. 5, 32 (2007).
    • (2007) BMC Biol. , vol.5 , pp. 32
    • Hayden, C.1    Jorgensen, R.2
  • 37
    • 84890786431 scopus 로고    scopus 로고
    • Detailed analysis of putative genes encoding small proteins in legume genomes
    • Guillén, G. et al. Detailed analysis of putative genes encoding small proteins in legume genomes. Front. Plant Sci. 4, 208 (2013).
    • (2013) Front. Plant Sci. , vol.4 , pp. 208
    • Guillén, G.1
  • 38
    • 3242878575 scopus 로고    scopus 로고
    • CSTminer: A web tool for the identification of coding and noncoding conserved sequence tags through cross-species genome comparison
    • Castrignanò, T. et al. CSTminer: a web tool for the identification of coding and noncoding conserved sequence tags through cross-species genome comparison. Nucleic Acids Res. 32, W624-W627 (2004).
    • (2004) Nucleic Acids Res. , vol.32
    • Castrignanò, T.1
  • 39
    • 0032900737 scopus 로고    scopus 로고
    • CRITICA: Coding region identification tool invoking comparative analysis
    • Badger, J. H. & Olsen, G. J. CRITICA: coding region identification tool invoking comparative analysis. Mol. Biol. Evol. 16, 512-524 (1999).
    • (1999) Mol. Biol. Evol. , vol.16 , pp. 512-524
    • Badger, J.H.1    Olsen, G.J.2
  • 40
    • 34547582418 scopus 로고    scopus 로고
    • CPC: Assess the protein-coding potential of transcripts using sequence features and support vector machine
    • Kong, L. et al. CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine. Nucleic Acids Res. 35, W345-W349 (2007).
    • (2007) Nucleic Acids Res. , vol.35
    • Kong, L.1
  • 41
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • Wang, Z., Gerstein, M. & Snyder, M. RNA-Seq: a revolutionary tool for transcriptomics. Nature Rev. Genet. 10, 57-63 (2009).
    • (2009) Nature Rev. Genet. , vol.10 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 42
    • 53549123008 scopus 로고    scopus 로고
    • Nature nurture, or chance: Stochastic gene expression and its consequences
    • Raj, A. & van Oudenaarden, A. Nature, nurture, or chance: stochastic gene expression and its consequences. Cell 135, 216-226 (2008).
    • (2008) Cell , vol.135 , pp. 216-226
    • Raj, A.1    Van Oudenaarden, A.2
  • 43
    • 62549134121 scopus 로고    scopus 로고
    • Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
    • Ingolia, N. T., Ghaemmaghami, S., Newman, J. R. S. & Weissman, J. S. Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 324, 218-223 (2009).
    • (2009) Science , vol.324 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.S.3    Weissman, J.S.4
  • 44
    • 84879969127 scopus 로고    scopus 로고
    • Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins
    • Guttman, M., Russell, P., Ingolia, N. T., Weissman, J. S. & Lander, E. S. Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins. Cell 154, 240-251 (2013).
    • (2013) Cell , vol.154 , pp. 240-251
    • Guttman, M.1    Russell, P.2    Ingolia, N.T.3    Weissman, J.S.4    Lander, E.S.5
  • 45
    • 78751653049 scopus 로고    scopus 로고
    • Mass spectrometry at the interface of proteomics and genomics
    • Krug, K., Nahnsen, S. & Macek, B. Mass spectrometry at the interface of proteomics and genomics. Mol. BioSystems 7, 284-291 (2011).
    • (2011) Mol. BioSystems , vol.7 , pp. 284-291
    • Krug, K.1    Nahnsen, S.2    MacEk, B.3
  • 46
    • 0037012881 scopus 로고    scopus 로고
    • Large-scale transcriptional activity in chromosomes 21 and 22
    • Kapranov, P. et al. Large-scale transcriptional activity in chromosomes 21 and 22. Science 296, 916-919 (2002).
    • (2002) Science , vol.296 , pp. 916-919
    • Kapranov, P.1
  • 47
    • 0142104045 scopus 로고    scopus 로고
    • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
    • Okazaki, Y. et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature 420, 563-573 (2002).
    • (2002) Nature , vol.420 , pp. 563-573
    • Okazaki, Y.1
  • 48
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • Birney, E. et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 447, 799-816 (2007).
    • (2007) Nature , vol.447 , pp. 799-816
    • Birney, E.1
  • 49
    • 79960911703 scopus 로고    scopus 로고
    • The reality of pervasive transcription
    • Clark, M. B. et al. The reality of pervasive transcription. PLoS Biol. 9, e1000625 (2011).
    • (2011) PLoS Biol. , vol.9
    • Clark, M.B.1
  • 50
    • 77952905505 scopus 로고    scopus 로고
    • Most dark matter transcripts are associated with known genes
    • van Bakel, H., Nislow, C., Blencowe, B. J. & Hughes, T. R. Most "dark matter" transcripts are associated with known genes. PLoS Biol. 8, e1000371 (2010).
    • (2010) PLoS Biol. , vol.8
    • Van Bakel, H.1    Nislow, C.2    Blencowe, B.J.3    Hughes, T.R.4
  • 51
    • 33846984935 scopus 로고    scopus 로고
    • Transcriptional noise and the fidelity of initiation by RNA polymerase II
    • Struhl, K. Transcriptional noise and the fidelity of initiation by RNA polymerase II. Nature Struct. Mol. Biol. 14, 103-105 (2007).
    • (2007) Nature Struct. Mol. Biol. , vol.14 , pp. 103-105
    • Struhl, K.1
  • 52
    • 0038349948 scopus 로고    scopus 로고
    • Sequencing and comparison of yeast species to identify genes and regulatory elements
    • Kellis, M., Patterson, N., Endrizzi, M., Birren, B. & Lander, E. S. Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423, 241-254 (2003).
    • (2003) Nature , vol.423 , pp. 241-254
    • Kellis, M.1    Patterson, N.2    Endrizzi, M.3    Birren, B.4    Lander, E.S.5
  • 53
    • 80053560943 scopus 로고    scopus 로고
    • Coding versus non-coding: Translatability of short ORFs found in putative non-coding transcripts
    • Kageyama, Y., Kondo, T. & Hashimoto, Y. Coding versus non-coding: translatability of short ORFs found in putative non-coding transcripts. Biochimie 93, 1981-1986 (2011).
    • (2011) Biochimie , vol.93 , pp. 1981-1986
    • Kageyama, Y.1    Kondo, T.2    Hashimoto, Y.3
  • 54
    • 84865727393 scopus 로고    scopus 로고
    • The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
    • Derrien, T. et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 22, 1775-1789 (2012).
    • (2012) Genome Res. , vol.22 , pp. 1775-1789
    • Derrien, T.1
  • 55
    • 17044409660 scopus 로고    scopus 로고
    • UAUG and uORFs in human and rodent 5?untranslated mRNAs
    • Iacono, M., Mignone, F. & Pesole, G. uAUG and uORFs in human and rodent 5?untranslated mRNAs. Gene 349, 97-105 (2005).
    • (2005) Gene , vol.349 , pp. 97-105
    • Iacono, M.1    Mignone, F.2    Pesole, G.3
  • 56
    • 33646136452 scopus 로고    scopus 로고
    • Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides
    • Crowe, M., Wang, X.-Q. & Rothnagel, J. A. Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides. BMC Genomics 7, 16 (2006).
    • (2006) BMC Genomics , vol.7 , pp. 16
    • Crowe, M.1    Wang, X.-Q.2    Rothnagel, J.A.3
  • 57
    • 34547774618 scopus 로고    scopus 로고
    • Dual modes of natural selection on upstream open reading frames
    • Neafsey, D. E. & Galagan, J. E. Dual modes of natural selection on upstream open reading frames. Mol. Biol. Evol. 24, 1744-1751 (2007).
    • (2007) Mol. Biol. Evol. , vol.24 , pp. 1744-1751
    • Neafsey, D.E.1    Galagan, J.E.2
  • 58
    • 34548512248 scopus 로고    scopus 로고
    • Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation
    • Cvijovic, M., Dalevi, D., Bilsland, E., Kemp, G. & Sunnerhagen, P. Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation. BMC Bioinformatics 8, 295 (2007).
    • (2007) BMC Bioinformatics , vol.8 , pp. 295
    • Cvijovic, M.1    Dalevi, D.2    Bilsland, E.3    Kemp, G.4    Sunnerhagen, P.5
  • 59
    • 50549100596 scopus 로고    scopus 로고
    • Conserved upstream open reading frames in higher plants
    • Tran, M., Schultz, C. & Baumann, U. Conserved upstream open reading frames in higher plants. BMC Genomics 9, 361 (2008).
    • (2008) BMC Genomics , vol.9 , pp. 361
    • Tran, M.1    Schultz, C.2    Baumann, U.3
  • 60
    • 84857388545 scopus 로고    scopus 로고
    • Known and novel post-transcriptional regulatory sequences are conserved across plant families
    • Vaughn, J. N., Ellingson, S. R., Mignone, F. & von Arnim, A. Known and novel post-transcriptional regulatory sequences are conserved across plant families. RNA 18, 368-384 (2012).
    • (2012) RNA , vol.18 , pp. 368-384
    • Vaughn, J.N.1    Ellingson, S.R.2    Mignone, F.3    Von Arnim, A.4
  • 61
    • 77957195626 scopus 로고    scopus 로고
    • Upstream open reading frames: Molecular switches in (patho) physiology
    • Wethmar, K., Smink, J. J. & Leutz, A. Upstream open reading frames: molecular switches in (patho) physiology. BioEssays 32, 885-893 (2010).
    • (2010) BioEssays , vol.32 , pp. 885-893
    • Wethmar, K.1    Smink, J.J.2    Leutz, A.3
  • 62
    • 0034736511 scopus 로고    scopus 로고
    • Analysis of oligonucleotide AUG start codon context in eukariotic mRNAs
    • Pesole, G. et al. Analysis of oligonucleotide AUG start codon context in eukariotic mRNAs. Gene 261, 85-91 (2000).
    • (2000) Gene , vol.261 , pp. 85-91
    • Pesole, G.1
  • 63
    • 0343069798 scopus 로고    scopus 로고
    • Statistical analysis of the 5? Untranslated region of human mRNA using oligo-capped cDNA libraries
    • Suzuki, Y. et al. Statistical analysis of the 5? Untranslated region of human mRNA using "oligo-capped" cDNA libraries. Genomics 64, 286-297 (2000).
    • (2000) Genomics , vol.64 , pp. 286-297
    • Suzuki, Y.1
  • 64
    • 0034781576 scopus 로고    scopus 로고
    • Presence of ATG triplets in 5? Untranslated regions of eukaryotic cDNAs correlates with a 'weak' context of the start codon
    • Rogozin, I. B., Kochetov, A. V., Kondrashov, F. A., Koonin, E. V. & Milanesi, L. Presence of ATG triplets in 5? Untranslated regions of eukaryotic cDNAs correlates with a 'weak' context of the start codon. Bioinformatics 17, 890-900 (2001).
    • (2001) Bioinformatics , vol.17 , pp. 890-900
    • Rogozin, I.B.1    Kochetov, A.V.2    Kondrashov, F.A.3    Koonin, E.V.4    Milanesi, L.5
  • 65
    • 0345860903 scopus 로고    scopus 로고
    • Small open reading frames in 5? Untranslated regions of mRNAs
    • Yamashita, R., Suzuki, Y., Nakai, K. & Sugano, S. Small open reading frames in 5? Untranslated regions of mRNAs. C. R. Biol. 326, 987-991 (2003).
    • (2003) C. R. Biol. , vol.326 , pp. 987-991
    • Yamashita, R.1    Suzuki, Y.2    Nakai, K.3    Sugano, S.4
  • 66
    • 79959834852 scopus 로고    scopus 로고
    • Exploring the selective constraint on the sizes of insertions and deletions in 5? Untranslated regions in mammals
    • Chen, C. H., Liao, B. Y. & Chen, F. C. Exploring the selective constraint on the sizes of insertions and deletions in 5? Untranslated regions in mammals. BMC Evol. Biol. 11, 192 (2011).
    • (2011) BMC Evol. Biol. , vol.11 , pp. 192
    • Chen, C.H.1    Liao, B.Y.2    Chen, F.C.3
  • 67
    • 42549161129 scopus 로고    scopus 로고
    • Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts
    • Ribrioux, S., Brungger, A., Baumgarten, B., Seuwen, K. & John, M. R. Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts. BMC Genomics 9, 122 (2008).
    • (2008) BMC Genomics , vol.9 , pp. 122
    • Ribrioux, S.1    Brungger, A.2    Baumgarten, B.3    Seuwen, K.4    John, M.R.5
  • 68
    • 84868324214 scopus 로고    scopus 로고
    • Observation of dually decoded regions of the human genome using ribosome profiling data
    • Michel, A. M. et al. Observation of dually decoded regions of the human genome using ribosome profiling data. Genome Res. 22, 2219-2229 (2012).
    • (2012) Genome Res. , vol.22 , pp. 2219-2229
    • Michel, A.M.1
  • 70
    • 77950529397 scopus 로고    scopus 로고
    • Length of the ORF, position of the first AUG and the Kozak motif are important factors in potential dual-coding transcripts
    • Xu, H. et al. Length of the ORF, position of the first AUG and the Kozak motif are important factors in potential dual-coding transcripts. Cell Res. 20, 445-457 (2010).
    • (2010) Cell Res. , vol.20 , pp. 445-457
    • Xu, H.1
  • 71
    • 79953673245 scopus 로고    scopus 로고
    • Expression of distinct RNAs from 3? Untranslated regions
    • Mercer, T. R. et al. Expression of distinct RNAs from 3? Untranslated regions. Nucleic Acids Res. 39, 2393-2403 (2011).
    • (2011) Nucleic Acids Res. , vol.39 , pp. 2393-2403
    • Mercer, T.R.1
  • 72
    • 84878865619 scopus 로고    scopus 로고
    • Ribosome profiling reveals resemblance between long non-coding RNAs and 5? Leaders of coding RNAs
    • Chew, G.-L. et al. Ribosome profiling reveals resemblance between long non-coding RNAs and 5? leaders of coding RNAs. Development 140, 2828-2834 (2013).
    • (2013) Development , vol.140 , pp. 2828-2834
    • Chew, G.-L.1
  • 73
    • 84865839598 scopus 로고    scopus 로고
    • Long noncoding RNAs are rarely translated in two human cell lines
    • Bánfai, B. et al. Long noncoding RNAs are rarely translated in two human cell lines. Genome Res. 22, 1646-1657 (2012).
    • (2012) Genome Res. , vol.22 , pp. 1646-1657
    • Bánfai, B.1
  • 74
    • 84873479857 scopus 로고    scopus 로고
    • Small open reading frames associated with morphogenesis are hidden in plant genomes
    • Hanada, K. et al. Small open reading frames associated with morphogenesis are hidden in plant genomes. Proc. Natl Acad. Sci. 110, 2395-2400 (2013).
    • (2013) Proc. Natl Acad. Sci. , vol.110 , pp. 2395-2400
    • Hanada, K.1
  • 75
    • 7444253965 scopus 로고    scopus 로고
    • Analysis of small human proteins reveals the translation of upstream open reading frames of mRNAs
    • Oyama, M. et al. Analysis of small human proteins reveals the translation of upstream open reading frames of mRNAs. Genome Res. 14, 2048-2052 (2004).
    • (2004) Genome Res. , vol.14 , pp. 2048-2052
    • Oyama, M.1
  • 76
    • 34347392057 scopus 로고    scopus 로고
    • Diversity of translation start sites may define increased complexity of the human short ORFeome
    • Oyama, M. et al. Diversity of translation start sites may define increased complexity of the human short ORFeome. Mol. Cell. Proteom. 6, 1000-1006 (2007).
    • (2007) Mol. Cell. Proteom. , vol.6 , pp. 1000-1006
    • Oyama, M.1
  • 77
    • 0029862690 scopus 로고    scopus 로고
    • Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen
    • Wang, R. F., Parkhurst, M. R., Kawakami, Y., Robbins, P. F. & Rosenberg, S. A. Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen. J. Exp. Med. 183, 1131-1140 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 1131-1140
    • Wang, R.F.1    Parkhurst, M.R.2    Kawakami, Y.3    Robbins, P.F.4    Rosenberg, S.A.5
  • 78
    • 0033168153 scopus 로고    scopus 로고
    • A non-AUG-defined alternative open reading frame of the intestinal carboxyl esterase mRNA generates an epitope recognized by renal cell carcinoma-reactive tumor-infiltrating lymphocytes in situ
    • Ronsin, C. et al. A non-AUG-defined alternative open reading frame of the intestinal carboxyl esterase mRNA generates an epitope recognized by renal cell carcinoma-reactive tumor-infiltrating lymphocytes in situ. J. Immunol. 163, 483-490 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 483-490
    • Ronsin, C.1
  • 79
    • 0037076219 scopus 로고    scopus 로고
    • A small, novel protein highly conserved in plants and animals promotes the polarized growth and division of maize leaf epidermal cells
    • Frank, M. J. & Smith, L. G. A small, novel protein highly conserved in plants and animals promotes the polarized growth and division of maize leaf epidermal cells. Curr. Biol. 12, 849-853 (2002).
    • (2002) Curr. Biol. , vol.12 , pp. 849-853
    • Frank, M.J.1    Smith, L.G.2
  • 81
    • 84894377781 scopus 로고    scopus 로고
    • The POLARIS gene of Arabidopsis encodes a predicted peptide required for correct root growth and leaf vascular patterning
    • Stuart, A. et al. The POLARIS gene of Arabidopsis encodes a predicted peptide required for correct root growth and leaf vascular patterning. Plant Cell 14, 16 (2002).
    • (2002) Plant Cell , vol.14 , pp. 16
    • Stuart, A.1
  • 82
    • 2542525473 scopus 로고    scopus 로고
    • Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell proliferation and alters leaf shape in Arabidopsis thaliana
    • Narita, N. N. et al. Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell proliferation and alters leaf shape in Arabidopsis thaliana. Plant J. 38, 699-713 (2004).
    • (2004) Plant J. , vol.38 , pp. 699-713
    • Narita, N.N.1
  • 83
    • 36749030603 scopus 로고    scopus 로고
    • HSPC300 and its role in neuronal connectivity
    • Abrar, Q. et al. HSPC300 and its role in neuronal connectivity. Neural Dev. 2, 18 (2007).
    • (2007) Neural Dev. , vol.2 , pp. 18
    • Abrar, Q.1
  • 84
    • 84860491077 scopus 로고    scopus 로고
    • Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing
    • Colombani, J., Andersen, D. S. & L?pold, P. Secreted peptide Dilp8 coordinates Drosophila tissue growth with developmental timing. Science 336, 582-585 (2012).
    • (2012) Science , vol.336 , pp. 582-585
    • Colombani, J.1    Andersen, D.S.2    Lpold, P.3
  • 85
    • 84860487216 scopus 로고    scopus 로고
    • Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation
    • Garelli, A., Gontijo, A. M., Miguela, V., Caparros, E. & Dominguez, M. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation. Science 336, 579-582 (2012).
    • (2012) Science , vol.336 , pp. 579-582
    • Garelli, A.1    Gontijo, A.M.2    Miguela, V.3    Caparros, E.4    Dominguez, M.5
  • 86
    • 84883487014 scopus 로고    scopus 로고
    • Conserved regulation of cardiac calcium uptake by peptides encoded in small open reading frames
    • Magny, E. G. et al. Conserved regulation of cardiac calcium uptake by peptides encoded in small open reading frames. Science 341, 1116-1120 (2013).
    • (2013) Science , vol.341 , pp. 1116-1120
    • Magny, E.G.1
  • 87
    • 34249021370 scopus 로고    scopus 로고
    • Peptides encoded by short ORFs control development and define a new eukaryotic gene family
    • Galindo, M. I., Pueyo, J. I., Fouix, S., Bishop, S. A. & Couso, J. P. Peptides encoded by short ORFs control development and define a new eukaryotic gene family. PLoS Biol. 5, e106 (2007).
    • (2007) PLoS Biol. , vol.5
    • Galindo, M.I.1    Pueyo, J.I.2    Fouix, S.3    Bishop, S.A.4    Couso, J.P.5
  • 88
    • 34447573973 scopus 로고    scopus 로고
    • Small peptide regulators of actin-based cell morphogenesis encoded by a polycistronic mRNA
    • Kondo, T. et al. Small peptide regulators of actin-based cell morphogenesis encoded by a polycistronic mRNA. Nature Cell Biol. 9, 660-665 (2007).
    • (2007) Nature Cell Biol. , vol.9 , pp. 660-665
    • Kondo, T.1
  • 89
    • 77954786287 scopus 로고    scopus 로고
    • Small peptides switch the transcriptional activity of Shavenbaby during Drosophila embryogenesis
    • Kondo, T. et al. Small peptides switch the transcriptional activity of Shavenbaby during Drosophila embryogenesis. Science 329, 336-339 (2010).
    • (2010) Science , vol.329 , pp. 336-339
    • Kondo, T.1
  • 90
    • 33746736922 scopus 로고    scopus 로고
    • A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides
    • Savard, J., Marques-Souza, H., Aranda, M. & Tautz, D. A segmentation gene in tribolium produces a polycistronic mRNA that codes for multiple conserved peptides. Cell 126, 559-569 (2006).
    • (2006) Cell , vol.126 , pp. 559-569
    • Savard, J.1    Marques-Souza, H.2    Aranda, M.3    Tautz, D.4
  • 91
    • 0036731785 scopus 로고    scopus 로고
    • Ovol2, a mammalian homolog of Drosophila Ovo: Gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice
    • Li, B. et al. Ovol2, a mammalian homolog of Drosophila Ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice. Genomics 80, 319-325 (2002).
    • (2002) Genomics , vol.80 , pp. 319-325
    • Li, B.1
  • 92
    • 84885402965 scopus 로고    scopus 로고
    • Conserved-peptide upstream open reading frames (CPuORFs) are associated with regulatory genes in angiosperms
    • Jorgensen, R. A. & Dorantes-Acosta, A. E. Conserved-peptide upstream open reading frames (CPuORFs) are associated with regulatory genes in angiosperms. Front. Plant Sci. 3, 191 (2012).
    • (2012) Front. Plant Sci. , vol.3 , pp. 191
    • Jorgensen, R.A.1    Dorantes-Acosta, A.E.2
  • 93
    • 0023659507 scopus 로고
    • The leader peptide of yeast gene CPA1 is essential for the translational repression of its expression
    • Werner, M., Feller, A., Messenguy, F. & Pi?ard, A. The leader peptide of yeast gene CPA1 is essential for the translational repression of its expression. Cell 49, 805-813 (1987).
    • (1987) Cell , vol.49 , pp. 805-813
    • Werner, M.1    Feller, A.2    Messenguy, F.3    Piard, A.4
  • 94
    • 27644520989 scopus 로고    scopus 로고
    • Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay
    • Gaba, A., Jacobson, A. & Sachs, M. S. Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay. Mol. Cell 20, 449-460 (2005).
    • (2005) Mol. Cell , vol.20 , pp. 449-460
    • Gaba, A.1    Jacobson, A.2    Sachs, M.S.3
  • 95
    • 67650123654 scopus 로고    scopus 로고
    • Sucrose control of translation mediated by an upstream open reading frame-encoded peptide
    • Rahmani, F. et al. Sucrose control of translation mediated by an upstream open reading frame-encoded peptide. Plant Physiol. 150, 1356-1367 (2009).
    • (2009) Plant Physiol. , vol.150 , pp. 1356-1367
    • Rahmani, F.1
  • 96
    • 28244500966 scopus 로고    scopus 로고
    • A dual upstream open reading frame-based autoregulatory circuit controlling polyamine-responsive translation
    • Hanfrey, C. et al. A dual upstream open reading frame-based autoregulatory circuit controlling polyamine-responsive translation. J. Biol. Chem. 280, 39229-39237 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 39229-39237
    • Hanfrey, C.1
  • 97
    • 84865757184 scopus 로고    scopus 로고
    • Translational regulation of Arabidopsis XIPOTL1 is modulated by phosphocholine levels via the phylogenetically conserved upstream open reading frame 30
    • Alatorre-Cobos, F. et al. Translational regulation of Arabidopsis XIPOTL1 is modulated by phosphocholine levels via the phylogenetically conserved upstream open reading frame 30. J. Exp. Bot. 63, 5203-5221 (2012).
    • (2012) J. Exp. Bot. , vol.63 , pp. 5203-5221
    • Alatorre-Cobos, F.1
  • 98
    • 0034745378 scopus 로고    scopus 로고
    • 5?UTR sequences of the glucocorticoid receptor 1A transcript encode a peptide associated with translational regulation of the glucocorticoid receptor
    • Diba, F., Watson, C. S. & Gametchu, B. 5?UTR sequences of the glucocorticoid receptor 1A transcript encode a peptide associated with translational regulation of the glucocorticoid receptor. J. Cell. Biochem. 81, 149-161 (2001).
    • (2001) J. Cell. Biochem. , vol.81 , pp. 149-161
    • Diba, F.1    Watson, C.S.2    Gametchu, B.3
  • 99
    • 21244451600 scopus 로고    scopus 로고
    • Regulation of endothelial argininosuccinate synthase expression and NO production by an upstream open reading frame
    • Pendleton, L. C., Goodwin, B. L., Solomonson, L. P. & Eichler, D. C. Regulation of endothelial argininosuccinate synthase expression and NO production by an upstream open reading frame. J. Biol. Chem. 280, 24252-24260 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 24252-24260
    • Pendleton, L.C.1    Goodwin, B.L.2    Solomonson, L.P.3    Eichler, D.C.4
  • 100
    • 84878087993 scopus 로고    scopus 로고
    • Expression of a novel mRNA transcript for human microsomal epoxide hydrolase (EPHX1) is regulated by short open reading frames within its 5?-untranslated region
    • Nguyen, H. L., Yang, X. & Omiecinski, C. J. Expression of a novel mRNA transcript for human microsomal epoxide hydrolase (EPHX1) is regulated by short open reading frames within its 5?-untranslated region. RNA 19, 752-766 (2013).
    • (2013) RNA , vol.19 , pp. 752-766
    • Nguyen, H.L.1    Yang, X.2    Omiecinski, C.J.3
  • 101
    • 84873579097 scopus 로고    scopus 로고
    • Translational repression of the McKusick-Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites
    • Akimoto, C. et al. Translational repression of the McKusick-Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites. Biochim. Biophys. Acta. 1830, 2728-2738 (2013).
    • (2013) Biochim. Biophys. Acta. , vol.1830 , pp. 2728-2738
    • Akimoto, C.1
  • 102
    • 79960185504 scopus 로고    scopus 로고
    • An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein
    • Vanderperre, B. et al. An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein. FASEB J. 25, 2373-2386 (2011).
    • (2011) FASEB J. , vol.25 , pp. 2373-2386
    • Vanderperre, B.1
  • 103
    • 84881260172 scopus 로고    scopus 로고
    • An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein
    • Bergeron, D. et al. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein. J. Biol. Chem. 288, 21824-21835 (2013).
    • (2013) J. Biol. Chem. , vol.288 , pp. 21824-21835
    • Bergeron, D.1
  • 104
    • 84871519181 scopus 로고    scopus 로고
    • TALENs: A widely applicable technology for targeted genome editing
    • Joung, J. K. & Sander, J. D. TALENs: a widely applicable technology for targeted genome editing. Nature Rev. Mol. Cell Biol. 14, 49-55 (2013).
    • (2013) Nature Rev. Mol. Cell Biol. , vol.14 , pp. 49-55
    • Joung, J.K.1    Sander, J.D.2
  • 105
    • 84884856342 scopus 로고    scopus 로고
    • Cas9 as a versatile tool for engineering biology
    • Mali, P., Esvelt, K. M. & Church, G. M. Cas9 as a versatile tool for engineering biology. Nature Methods 10, 957-963 (2013).
    • (2013) Nature Methods , vol.10 , pp. 957-963
    • Mali, P.1    Esvelt, K.M.2    Church, G.M.3
  • 106
    • 78650873392 scopus 로고    scopus 로고
    • Regulation of protein function by 'microProteins'
    • Staudt, A. C. & Wenkel, S. Regulation of protein function by 'microProteins'. EMBO Rep. 12, 35-42 (2011).
    • (2011) EMBO Rep. , vol.12 , pp. 35-42
    • Staudt, A.C.1    Wenkel, S.2
  • 107
    • 66149118241 scopus 로고    scopus 로고
    • Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
    • Calvo, S. E., Pagliarini, D. J. & Mootha, V. K. Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans. Proc. Natl Acad. Sci. 106, 7507-7512 (2009).
    • (2009) Proc. Natl Acad. Sci. , vol.106 , pp. 7507-7512
    • Calvo, S.E.1    Pagliarini, D.J.2    Mootha, V.K.3
  • 108
    • 59149083659 scopus 로고    scopus 로고
    • Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis
    • Wen, Y. et al. Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis. Nature Genet. 41, 228-233 (2009).
    • (2009) Nature Genet. , vol.41 , pp. 228-233
    • Wen, Y.1
  • 109
    • 84865498226 scopus 로고    scopus 로고
    • Investigation of cytotoxicity of negative control peptides versus bioactive peptides on skin cancer and normal cells: A comparative study
    • Almansour, N. M., Pirogova, E., Coloe, P. J., Cosic, I. & Istivan, T. S. Investigation of cytotoxicity of negative control peptides versus bioactive peptides on skin cancer and normal cells: a comparative study. Future Med. Chem. 4, 1553-1565 (2012).
    • (2012) Future Med. Chem. , vol.4 , pp. 1553-1565
    • Almansour, N.M.1    Pirogova, E.2    Coloe, P.J.3    Cosic, I.4    Istivan, T.S.5
  • 110
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak, M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44, 283-292 (1986).
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 111
    • 0023425901 scopus 로고
    • Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes
    • Kozak, M. Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes. Mol. Cell. Biol. 7, 3438-3445 (1987).
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3438-3445
    • Kozak, M.1
  • 112
    • 0034459468 scopus 로고    scopus 로고
    • Upstream open reading frames as regulators of mRNA translation
    • Morris, D. R. & Geballe, A. P. Upstream open reading frames as regulators of mRNA translation. Mol. Cell. Biol. 20, 8635-8642 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8635-8642
    • Morris, D.R.1    Geballe, A.P.2
  • 113
    • 0032400867 scopus 로고    scopus 로고
    • Thrombopoietin production is inhibited by a translational mechanism
    • Ghilardi, N., Wiestner, A. & Skoda, R. C. Thrombopoietin production is inhibited by a translational mechanism. Blood 92, 4023-4030 (1998).
    • (1998) Blood , vol.92 , pp. 4023-4030
    • Ghilardi, N.1    Wiestner, A.2    Skoda, R.C.3
  • 114
    • 0033869876 scopus 로고    scopus 로고
    • Translational control of C/EBPα and C/EBPβ isoform expression
    • Calkhoven, C. F., Müller, C. & Leutz, A. Translational control of C/EBPα and C/EBPβ isoform expression. Genes Dev. 14, 1920-1932 (2000).
    • (2000) Genes Dev. , vol.14 , pp. 1920-1932
    • Calkhoven, C.F.1    Müller, C.2    Leutz, A.3
  • 115
    • 0030803256 scopus 로고    scopus 로고
    • Translational regulation of yeast GCN4
    • Hinnebusch, A. G. Translational regulation of yeast GCN4. J. Biol. Chem. 272, 21661-21664 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 21661-21664
    • Hinnebusch, A.G.1
  • 116
    • 0033588103 scopus 로고    scopus 로고
    • Translational control by an upstream open reading frame in the HER-2/neu transcript
    • Child, S. J., Miller, M. K. & Geballe, A. P. Translational control by an upstream open reading frame in the HER-2/neu transcript. J. Biol. Chem. 274, 24335-24341 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 24335-24341
    • Child, S.J.1    Miller, M.K.2    Geballe, A.P.3
  • 117
    • 0035846946 scopus 로고    scopus 로고
    • Post-transcriptional regulation of the GLI1 oncogene by the expression of alternative 5? Untranslated regions
    • Wang, X.-Q. & Rothnagel, J. A. Post-transcriptional regulation of the GLI1 oncogene by the expression of alternative 5? Untranslated regions. J. Biol. Chem. 276, 1311-1316 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 1311-1316
    • Wang, X.-Q.1    Rothnagel, J.A.2
  • 118
    • 2542589355 scopus 로고    scopus 로고
    • 5?-untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation
    • Wang, X. Q. & Rothnagel, J. A. 5?-untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation. Nucleic Acids Res. 32, 1382-1391 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1382-1391
    • Wang, X.Q.1    Rothnagel, J.A.2
  • 119
    • 0026342613 scopus 로고
    • An analysis of vertebrate mRNA sequences: Intimations of translational control
    • Kozak, M. An analysis of vertebrate mRNA sequences: intimations of translational control. J. Cell Biol. 115, 887-903 (1991).
    • (1991) J. Cell Biol. , vol.115 , pp. 887-903
    • Kozak, M.1
  • 120
    • 38949116410 scopus 로고    scopus 로고
    • Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells
    • Hanyu-Nakamura, K., Sonobe-Nojima, H., Tanigawa, A. & Lasko, P. Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells. Nature 451, 730-733 (2008).
    • (2008) Nature , vol.451 , pp. 730-733
    • Hanyu-Nakamura, K.1    Sonobe-Nojima, H.2    Tanigawa, A.3    Lasko, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.