The human transcriptome across tissues and individuals

Science

Volumn 348, Issue 6235, 2015, Pages 660-665

  Melé, Marta ^a,b   Ferreira, Pedro G ^a,c,d   Reverter, Ferran ^a,e,f   DeLuca, David S ^g   Monlong, Jean ^a,f,h   Sammeth, Michael ^a,f,i   Young, Taylor R ^g   Goldmann, Jakob M ^a,f,j   Pervouchine, Dmitri D ^a,f,k   Sullivan, Timothy J ^g   Johnson, Rory ^a,f   Segrè, Ayellet V ^g   Djebali, Sarah ^a,f   Niarchou, Anastasia ^c,d   Wright, Fred A ^l   Lappalainen, Tuuli ^c,d,m,n   Calvo, Miquel ^e   Getz, Gad ^g,o   Dermitzakis, Emmanouil T ^c,d   Ardlie, Kristin G ^g   Guigó, Roderic ^a,f,p,q   more..

^a CENTRE FOR GENOMIC REGULATION CRG   (Spain)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^e UNIVERSITY OF BARCELONA   (Spain)

^f UNIVERSITAT POMPEU FABRA   (Spain)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^h MCGILL UNIVERSITY   (Canada)

ⁱ LABORATÓRIO NACIONAL DE COMPUTAÇÃO CIENTÍFICA   (Brazil)

^j RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^k MOSCOW STATE UNIVERSITY   (Russian Federation)

^l NORTH CAROLINA STATE UNIVERSITY   (United States)

^m NEW YORK GENOME CENTER   (United States)

ⁿ Och Spine at New York Presbyterian Hospitals   (United States)

^o MASSACHUSETTS GENERAL HOSPITAL   (United States)

^p HOSPITAL DEL MAR   (Spain)

^q INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTOME;

CYTOLOGY; GENE EXPRESSION; GENOTYPE; PHENOTYPE; RNA; SAMPLING;

AGE; ARTICLE; CELL SPECIFICITY; ETHNICITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; PRIORITY JOURNAL; RNA SEQUENCE; RNA SPLICING; ALTERNATIVE RNA SPLICING; ANTIBODY SPECIFICITY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HUMAN GENOME; MALE; PHENOTYPE; SEQUENCE ANALYSIS; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

ALTERNATIVE SPLICING; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; MALE; ORGAN SPECIFICITY; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, RNA; SEX FACTORS; TRANSCRIPTOME;

EID: 84929015296     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa0355     Document Type: Article

References (23)

1. FANTOM Consortium and the RIKEN PMI and CLST (DGT) et al., Nature 507, 462-470 (2014).
2. ENCODE Project Consortium, Nature 489, 57-74 (2012).
3. T. Lappalainen et al., Nature 501, 506-511 (2013).
4. E. Grundberg et al., Nat. Genet. 44, 1084-1089 (2012).
5. T. J. Lonsdale et al., Nat. Genet. 45, 580-585 (2013).
6. The GTEx Consortium, Science 348, 648-660 (2015).
7. Materials and methods are available in the supplementary materials on Science Online.
8. D. S. DeLuca et al., Bioinformatics 28, 1530-1532 (2012).
9. J. Harrow et al., Genome Res. 22, 1760-1774 (2012).
10. M. Lukk et al., Nat. Biotechnol. 28, 322-324 (2010).
11. A. C. Birdsill, D. G. Walker, L. Lue, L. I. Sue, T. G. Beach, Cell Tissue Bank. 12, 311-318 (2011).
12. J. P. Brunet, P. Tamayo, T. R. Golub, J. P. Mesirov, Proc. Natl. Acad. Sci. U.S.A. 101, 4164-4169 (2004).
13. P. Carninci et al., Genome Res. 10, 1617-1630 (2000).
14. R. D. Kelly, A. Mahmud, M. McKenzie, I. A. Trounce, J. C. St John, Nucleic Acids Res. 40, 10124-10138 (2012).
15. D. Kelley, J. Rinn, Genome Biol. 13, R107 (2012).
16. L. Carrel, H. F. Willard, Nature 434, 400-404 (2005).
17. S. Djebali et al., Nature 489, 101-108 (2012).
18. V. Regitz-Zagrosek, U. Seeland, Wien. Med. Wochenschr. 161, 109 (2011).
19. M. Yan et al., Science 290, 523-527 (2000).
20. G. Yeo, D. Holste, G. Kreiman, C. B. Burge, Genome Biol. 5, R74 (2004).
21. J. K. Pickrell, A. A. Pai, Y. Gilad, J. K. Pritchard, PLOS Genet. 6, e1001236 (2010).
22. I. Ezkurdia et al., Mol. Biol. Evol. 29, 2265-2283 (2012).
23. M. Gonzàlez-Porta, A. Frankish, J. Rung, J. Harrow, A. Brazma, Genome Biol. 14, R70 (2013).