Quantitative analysis of single amino acid variant peptides associated with pancreatic cancer in serum by an isobaric labeling quantitative method

Journal of Proteome Research

Volumn 13, Issue 12, 2014, Pages 6058-6066

  Nie, Song ^a   Yin, Haidi ^a   Tan, Zhijing ^a   Anderson, Michelle A ^b   Ruffin, MacK T ^b   Simeone, Diane M ^a   Lubman, David M ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

biomarker; isobaric labeling; pancreatic cancer; proteomics; serum; single amino acid variant

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; AMINO ACID; SINGLE AMINO ACID VARIANT; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; PEPTIDE; PROTEOME; TUMOR MARKER;

ADULT; AMINO ACID BLOOD LEVEL; AMINO ACID SEQUENCE; ANALYTIC METHOD; ARTICLE; CHRONIC PANCREATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; OBSTRUCTIVE JAUNDICE; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PANCREAS CYST; QUANTITATIVE ANALYSIS; SELECTED REACTION MONITORING; AGED; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; METABOLISM; MIDDLE AGED; MISSENSE MUTATION; MOLECULAR GENETICS; PANCREAS TUMOR; PROCEDURES; PROTEOMICS; RECEIVER OPERATING CHARACTERISTIC; REPRODUCIBILITY; SINGLE NUCLEOTIDE POLYMORPHISM; TANDEM MASS SPECTROMETRY; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; BIOMARKERS, TUMOR; CHROMATOGRAPHY, LIQUID; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; ISOTOPE LABELING; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PANCREATIC NEOPLASMS; PEPTIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS; ROC CURVE; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 84915751033     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr500934u     Document Type: Article

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