Methionine to isothreonine conversion as a source of false discovery identifications of genetically encoded variants in proteogenomics

Journal of Proteomics

Volumn 120, Issue , 2015, Pages 169-178

  Chernobrovkin, Alexey L ^a,b   Kopylov, Arthur T ^a   Zgoda, Victor G ^a   Moysa, Alexander A ^a   Pyatnitskiy, Mikhail A ^a   Kuznetsova, Ksenia G ^a   Ilina, Irina Y ^a   Karpova, Maria A ^a   Karpov, Dmitry S ^a,c   Veselovsky, Alexander V ^a   Ivanov, Mark V ^d,e   Gorshkov, Mikhail V ^d,e   Archakov, Alexander I ^a   Moshkovskii, Sergei A ^a,f  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^d SEMENOV INSTITUTE OF CHEMICAL PHYSICS   (Russian Federation)

^e MOSCOW INSTITUTE OF PHYSICS AND TECHNOLOGY   (Russian Federation)

^f PIROGOV RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY   (Russian Federation)

Author keywords

Cancer cell line; Iodoacetamide; Isothreonine; Methionine; Proteogenomics; Tandem mass spectrometry

Indexed keywords

AMINO ACID; BOVINE SERUM ALBUMIN; CHAPERONE; IODOACETAMIDE; ISOTHREONINE; METHIONINE; NUCLEIC ACID; PEPTIDE FRAGMENT; PROTEOME; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; GENETIC MARKER; THREONINE;

ARTICLE; CANCER CELL LINE; GENOME; GENOMICS; HUMAN; LIQUID CHROMATOGRAPHY; MOLECULAR MODEL; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DATABASE; PROTEOGENOMICS; PROTEOMICS; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; AMINO ACID SUBSTITUTION; ARTIFACT; GENETIC MARKER; GENETIC VARIABILITY; GENETICS; LABORATORY DIAGNOSIS; NEOPLASM; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TUMOR CELL LINE;

BOVINAE;

AMINO ACID SUBSTITUTION; ARTIFACTS; CELL LINE, TUMOR; FALSE POSITIVE REACTIONS; GENETIC MARKERS; GENETIC VARIATION; HUMANS; METHIONINE; NEOPLASMS; PROTEOME; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THREONINE;

EID: 84925937233     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2015.03.003     Document Type: Article

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