-
1
-
-
79952649573
-
-
Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, USA
-
Green DR. Means To An End: Apoptosis, and Other Cell Death Mechanisms. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, USA, 2011, p 220.
-
(2011)
Means to An End: Apoptosis, and Other Cell Death Mechanisms
, pp. 220
-
-
Green, D.R.1
-
2
-
-
77956938316
-
A model to die for: Signaling to apoptotic cell removal in worm, fly, and mouse
-
Kinchen JM A model to die for: signaling to apoptotic cell removal in worm, fly, and mouse. Apoptosis. 2010; 15: 998-1006.
-
(2010)
Apoptosis
, vol.15
, pp. 998-1006
-
-
Kinchen, J.M.1
-
5
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP L) complex inhibits RIPK3-dependent necrosis
-
Oberst A, Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C, et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature. 2011; 471: 363-367.
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
-
6
-
-
80052179138
-
Caspase-1-induced pyroptotic cell death
-
Miao EA, Rajan JV, Aderem A. Caspase-1-induced pyroptotic cell death. Immunol Rev. 2011; 243: 206-214.
-
(2011)
Immunol Rev
, vol.243
, pp. 206-214
-
-
Miao, E.A.1
Rajan, J.V.2
Aderem, A.3
-
7
-
-
84966971852
-
Prix fixe: Efferocytosis as a four-course meal
-
Martinez J. Prix fixe: efferocytosis as a four-course meal. Curr Top Microbiol Immunol. 2015; 1-36.
-
(2015)
Curr Top Microbiol Immunol
, pp. 1-36
-
-
Martinez, J.1
-
8
-
-
84939625807
-
Phagocytosis of apoptotic cells in homeostasis
-
Arandjelovic S, Ravichandran KS. Phagocytosis of apoptotic cells in homeostasis. Nat Immunol. 2015; 16: 907-917.
-
(2015)
Nat Immunol
, vol.16
, pp. 907-917
-
-
Arandjelovic, S.1
Ravichandran, K.S.2
-
9
-
-
0037097756
-
Phagocytosis of apoptotic cells by liver: A morphological study
-
Dini L, Pagliara P, Carla EC. Phagocytosis of apoptotic cells by liver: a morphological study. Microsc Res Tech. 2002; 57: 530-540.
-
(2002)
Microsc Res Tech
, vol.57
, pp. 530-540
-
-
Dini, L.1
Pagliara, P.2
Carla, E.C.3
-
10
-
-
84937639203
-
Microglia function during brain development: New insights from animal models
-
Bilimoria PM, Stevens B. Microglia function during brain development: new insights from animal models. Brain Res. 2015; 1617: 7-17.
-
(2015)
Brain Res
, vol.1617
, pp. 7-17
-
-
Bilimoria, P.M.1
Stevens, B.2
-
11
-
-
84872930976
-
Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation
-
Juncadella IJ, Kadl A, Sharma AK, Shim YM, Hochreiter-Hufford A, Borish L, et al. Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation. Nature. 2013; 493: 547-551.
-
(2013)
Nature
, vol.493
, pp. 547-551
-
-
Juncadella, I.J.1
Kadl, A.2
Sharma, A.K.3
Shim, Y.M.4
Hochreiter-Hufford, A.5
Borish, L.6
-
12
-
-
77956945047
-
Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo
-
Elliott MR, Zheng S, Park D, Woodson RI, Reardon MA, Juncadella IJ, et al. Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo. Nature. 2010; 467: 333-337.
-
(2010)
Nature
, vol.467
, pp. 333-337
-
-
Elliott, M.R.1
Zheng, S.2
Park, D.3
Woodson, R.I.4
Reardon, M.A.5
Juncadella, I.J.6
-
13
-
-
84880551919
-
Noncanonical autophagy promotes the visual cycle
-
Kim JY, Zhao H, Martinez J, Doggett TA, Kolesnikov AV, Tang PH, et al. Noncanonical autophagy promotes the visual cycle. Cell. 2013; 154: 365-376.
-
(2013)
Cell
, vol.154
, pp. 365-376
-
-
Kim, J.Y.1
Zhao, H.2
Martinez, J.3
Doggett, T.A.4
Kolesnikov, A.V.5
Tang, P.H.6
-
14
-
-
77956913114
-
Dangerous attraction: Phagocyte recruitment, and danger signals of apoptotic, and necrotic cells
-
Peter C, Wesselborg S, Herrmann M, Lauber K. Dangerous attraction: phagocyte recruitment, and danger signals of apoptotic, and necrotic cells. Apoptosis. 2010; 15: 1007-1028.
-
(2010)
Apoptosis
, vol.15
, pp. 1007-1028
-
-
Peter, C.1
Wesselborg, S.2
Herrmann, M.3
Lauber, K.4
-
15
-
-
77956255766
-
Find-me, and eat-me signals in apoptotic cell clearance: Progress, and conundrums
-
Ravichandran KS. Find-me, and eat-me signals in apoptotic cell clearance: progress, and conundrums. J Exp Med. 2010; 207: 1807-1817.
-
(2010)
J Exp Med
, vol.207
, pp. 1807-1817
-
-
Ravichandran, K.S.1
-
17
-
-
77649152255
-
Autoimmunity, and the clearance of dead cells
-
Nagata S, Hanayama R, Kawane K. Autoimmunity, and the clearance of dead cells. Cell. 2010; 140: 619-630.
-
(2010)
Cell
, vol.140
, pp. 619-630
-
-
Nagata, S.1
Hanayama, R.2
Kawane, K.3
-
18
-
-
84896690342
-
Apoptotic cell clearance: Basic biology, and therapeutic potential
-
Poon IK, Lucas CD, Rossi AG, Ravichandran KS. Apoptotic cell clearance: basic biology, and therapeutic potential. Nat Rev Immunol. 2014; 14: 166-180.
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 166-180
-
-
Poon, I.K.1
Lucas, C.D.2
Rossi, A.G.3
Ravichandran, K.S.4
-
19
-
-
70249090374
-
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
-
Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF, et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature. 2009; 461: 282-286.
-
(2009)
Nature
, vol.461
, pp. 282-286
-
-
Elliott, M.R.1
Chekeni, F.B.2
Trampont, P.C.3
Lazarowski, E.R.4
Kadl, A.5
Walk, S.F.6
-
20
-
-
0033771902
-
CED-2/CrkII, and CED-10/Rac control phagocytosis, and cell migration in Caenorhabditis elegans
-
Reddien PW, Horvitz HR. CED-2/CrkII, and CED-10/Rac control phagocytosis, and cell migration in Caenorhabditis elegans. Nat Cell Biol. 2000; 2: 131-136.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 131-136
-
-
Reddien, P.W.1
Horvitz, H.R.2
-
21
-
-
0035849895
-
Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans
-
Hoeppner DJ, Hengartner MO, Schnabel R. Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans. Nature. 2001; 412: 202-206.
-
(2001)
Nature
, vol.412
, pp. 202-206
-
-
Hoeppner, D.J.1
Hengartner, M.O.2
Schnabel, R.3
-
22
-
-
84872027397
-
Clearing the dead: Apoptotic cell sensing, recognition, engulfment, and digestion
-
Hochreiter-Hufford A, Ravichandran KS. Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion. Cold Spring Harb Perspect Biol. 2013; 5: a008748.
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
, pp. a008748
-
-
Hochreiter-Hufford, A.1
Ravichandran, K.S.2
-
23
-
-
77957942834
-
Pannexin 1 channels mediate find-me signal release, and membrane permeability during apoptosis
-
Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER, et al. Pannexin 1 channels mediate find-me signal release, and membrane permeability during apoptosis. Nature. 2010; 467: 863-867.
-
(2010)
Nature
, vol.467
, pp. 863-867
-
-
Chekeni, F.B.1
Elliott, M.R.2
Sandilos, J.K.3
Walk, S.F.4
Kinchen, J.M.5
Lazarowski, E.R.6
-
24
-
-
58149398634
-
CX3CL1/.fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis
-
Truman LA, Ford CA, Pasikowska M, Pound JD, Wilkinson SJ, Dumitriu IE, et al. CX3CL1/.fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis. Blood. 2008; 112: 5026-5036.
-
(2008)
Blood
, vol.112
, pp. 5026-5036
-
-
Truman, L.A.1
Ford, C.A.2
Pasikowska, M.3
Pound, J.D.4
Wilkinson, S.J.5
Dumitriu, I.E.6
-
25
-
-
41949104092
-
Migration to apoptotic find-me signals is mediated via the phagocyte receptor G2A
-
Peter C, Waibel M, Radu CG, Yang LV, Witte ON, Schulze-Osthoff K, et al. Migration to apoptotic find-me signals is mediated via the phagocyte receptor G2A. J Biol Chem. 2008; 283: 5296-5305.
-
(2008)
J Biol Chem
, vol.283
, pp. 5296-5305
-
-
Peter, C.1
Waibel, M.2
Radu, C.G.3
Yang, L.V.4
Witte, O.N.5
Schulze-Osthoff, K.6
-
26
-
-
48749121214
-
Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a come-And get-me signal
-
Gude DR, Alvarez SE, Paugh SW, Mitra P, Yu J, Griffiths R, et al. Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a come-And get-me signal. FASEB J. 2008; 22: 2629-2638.
-
(2008)
FASEB J.
, vol.22
, pp. 2629-2638
-
-
Gude, D.R.1
Alvarez, S.E.2
Paugh, S.W.3
Mitra, P.4
Yu, J.5
Griffiths, R.6
-
27
-
-
73949118676
-
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
-
Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, et al. Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci USA. 2009; 106: 20388-20393.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20388-20393
-
-
Iyer, S.S.1
Pulskens, W.P.2
Sadler, J.J.3
Butter, L.M.4
Teske, G.J.5
Ulland, T.K.6
-
28
-
-
77149138338
-
Inhibition of eosinophil migration by lactoferrin
-
Bournazou I, Mackenzie KJ, Duffin R, Rossi AG, Gregory CD. Inhibition of eosinophil migration by lactoferrin. Immunol Cell Biol. 2010; 88: 220-223.
-
(2010)
Immunol Cell Biol
, vol.88
, pp. 220-223
-
-
Bournazou, I.1
Mackenzie, K.J.2
Duffin, R.3
Rossi, A.G.4
Gregory, C.D.5
-
29
-
-
61749084352
-
Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin
-
Bournazou I, Pound JD, Duffin R, Bournazos S, Melville LA, Brown SB, et al. Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin. J Clin Invest. 2009; 119: 20-32.
-
(2009)
J Clin Invest
, vol.119
, pp. 20-32
-
-
Bournazou, I.1
Pound, J.D.2
Duffin, R.3
Bournazos, S.4
Melville, L.A.5
Brown, S.B.6
-
30
-
-
77953187290
-
Uric acid promotes an acute inflammatory response to sterile cell death in mice
-
Kono H, Chen CJ, Ontiveros F, Rock KL. Uric acid promotes an acute inflammatory response to sterile cell death in mice. J Clin Invest. 2010; 120: 1939-1949.
-
(2010)
J Clin Invest
, vol.120
, pp. 1939-1949
-
-
Kono, H.1
Chen, C.J.2
Ontiveros, F.3
Rock, K.L.4
-
31
-
-
2442665179
-
Autoimmune disease, and impaired uptake of apoptotic cells in MFG-E8-deficient mice
-
Hanayama R, Tanaka M, Miyasaka K, Aozasa K, Koike M, Uchiyama Y, et al. Autoimmune disease, and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science. 2004; 304: 1147-1150.
-
(2004)
Science
, vol.304
, pp. 1147-1150
-
-
Hanayama, R.1
Tanaka, M.2
Miyasaka, K.3
Aozasa, K.4
Koike, M.5
Uchiyama, Y.6
-
32
-
-
84856789589
-
Two-step engulfment of apoptotic cells
-
Toda S, Hanayama R, Nagata S. Two-step engulfment of apoptotic cells. Mol Cell Biol. 2012; 32: 118-125.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 118-125
-
-
Toda, S.1
Hanayama, R.2
Nagata, S.3
-
33
-
-
77956940121
-
Clearance of dead cells: Mechanisms, immune responses, and implication in the development of diseases
-
Krysko DV, Vandenabeele P. Clearance of dead cells: mechanisms, immune responses, and implication in the development of diseases. Apoptosis. 2010; 15: 995-997.
-
(2010)
Apoptosis
, vol.15
, pp. 995-997
-
-
Krysko, D.V.1
Vandenabeele, P.2
-
34
-
-
0037938686
-
Aminophospholipid asymmetry: A matter of life, and death
-
Balasubramanian K, Schroit AJ. Aminophospholipid asymmetry: a matter of life, and death. Ann Rev Physiol. 2003; 65: 701-734.
-
(2003)
Ann Rev Physiol
, vol.65
, pp. 701-734
-
-
Balasubramanian, K.1
Schroit, A.J.2
-
35
-
-
84880758440
-
Xk-related protein 8, and CED-8 promote phosphatidylserine exposure in apoptotic cells
-
Suzuki J, Denning DP, Imanishi E, Horvitz HR, Nagata S. Xk-related protein 8, and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science. 2013; 341: 403-406.
-
(2013)
Science
, vol.341
, pp. 403-406
-
-
Suzuki, J.1
Denning, D.P.2
Imanishi, E.3
Horvitz, H.R.4
Nagata, S.5
-
36
-
-
84901849205
-
Caspasemediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure
-
Segawa K, Kurata S, Yanagihashi Y, Brummelkamp TR, Matsuda F, Nagata S. Caspasemediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure. Science. 2014; 344: 1164-1168.
-
(2014)
Science
, vol.344
, pp. 1164-1168
-
-
Segawa, K.1
Kurata, S.2
Yanagihashi, Y.3
Brummelkamp, T.R.4
Matsuda, F.5
Nagata, S.6
-
37
-
-
77952687335
-
T, and B cell hyperactivity, and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice
-
Rodriguez-Manzanet R, Sanjuan MA, Wu HY, Quintana FJ, Xiao S, Anderson AC, et al. T, and B cell hyperactivity, and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice. Proc Natl Acad Sci USA. 2010; 107: 8706-8711.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8706-8711
-
-
Rodriguez-Manzanet, R.1
Sanjuan, M.A.2
Wu, H.Y.3
Quintana, F.J.4
Xiao, S.5
Anderson, A.C.6
-
38
-
-
36248987290
-
BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
-
Park D, Tosello-Trampont AC, Elliott MR, Lu M, Haney LB, Ma Z, et al. BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature. 2007; 450: 430-434.
-
(2007)
Nature
, vol.450
, pp. 430-434
-
-
Park, D.1
Tosello-Trampont, A.C.2
Elliott, M.R.3
Lu, M.4
Haney, L.B.5
Ma, Z.6
-
39
-
-
37349029518
-
Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor
-
Park SY, Jung MY, Kim HJ, Lee SJ, Kim SY, Lee BH, et al. Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor. Cell Death Differ. 2008; 15: 192-201.
-
(2008)
Cell Death Differ
, vol.15
, pp. 192-201
-
-
Park, S.Y.1
Jung, M.Y.2
Kim, H.J.3
Lee, S.J.4
Kim, S.Y.5
Lee, B.H.6
-
40
-
-
0037046580
-
Identification of a factor that links apoptotic cells to phagocytes
-
Hanayama R, Tanaka M, Miwa K, Shinohara A, Iwamatsu A, Nagata S. Identification of a factor that links apoptotic cells to phagocytes. Nature. 2002; 417: 182-187.
-
(2002)
Nature
, vol.417
, pp. 182-187
-
-
Hanayama, R.1
Tanaka, M.2
Miwa, K.3
Shinohara, A.4
Iwamatsu, A.5
Nagata, S.6
-
41
-
-
0034073163
-
Promotion of the uptake of PS liposomes, and apoptotic cells by a product of growth arrest-specific gene, gas6
-
Ishimoto Y, Ohashi K, Mizuno K, Nakano T. Promotion of the uptake of PS liposomes, and apoptotic cells by a product of growth arrest-specific gene, gas6. J Biochem. 2000; 127: 411-417.
-
(2000)
J Biochem
, vol.127
, pp. 411-417
-
-
Ishimoto, Y.1
Ohashi, K.2
Mizuno, K.3
Nakano, T.4
-
42
-
-
84866554651
-
Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization, and MerTK induction
-
Zizzo G, Hilliard BA, Monestier M, Cohen PL. Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization, and MerTK induction. J Immunol. 2012; 189: 3508-3520.
-
(2012)
J Immunol
, vol.189
, pp. 3508-3520
-
-
Zizzo, G.1
Hilliard, B.A.2
Monestier, M.3
Cohen, P.L.4
-
43
-
-
0032445073
-
Roles of ICAM-3, and CD14 in the recognition, and phagocytosis of apoptotic cells by macrophages
-
Gregory CD, Devitt A, Moffatt O. Roles of ICAM-3, and CD14 in the recognition, and phagocytosis of apoptotic cells by macrophages. Biochem Soc Trans. 1998; 26: 644-649.
-
(1998)
Biochem Soc Trans
, vol.26
, pp. 644-649
-
-
Gregory, C.D.1
Devitt, A.2
Moffatt, O.3
-
44
-
-
26844468253
-
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through transactivation of LRP on the phagocyte
-
Gardai SJ, McPhillips KA, Frasch SC, Janssen WJ, Starefeldt A, Murphy-Ullrich JE, et al. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through transactivation of LRP on the phagocyte. Cell. 2005; 123: 321-334.
-
(2005)
Cell
, vol.123
, pp. 321-334
-
-
Gardai, S.J.1
McPhillips, K.A.2
Frasch, S.C.3
Janssen, W.J.4
Starefeldt, A.5
Murphy-Ullrich, J.E.6
-
45
-
-
0032972614
-
Macrophage-restricted molecules: Role in differentiation, and activation
-
Gordon S. Macrophage-restricted molecules: role in differentiation, and activation. Immunol Lett. 1999; 65: 5-8.
-
(1999)
Immunol Lett
, vol.65
, pp. 5-8
-
-
Gordon, S.1
-
46
-
-
0025608606
-
Molecular characterization of the human macrophage mannose receptor: Demonstration of multiple carbohydrate recognition-like domains, and phagocytosis of yeasts in Cos-1 cells
-
Ezekowitz RA, Sastry K, Bailly P, Warner A. Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains, and phagocytosis of yeasts in Cos-1 cells. J Exp Med. 1990; 172: 1785-1794.
-
(1990)
J Exp Med
, vol.172
, pp. 1785-1794
-
-
Ezekowitz, R.A.1
Sastry, K.2
Bailly, P.3
Warner, A.4
-
47
-
-
82755163551
-
Constitutive exposure of phosphatidylserine on viable cells
-
Segawa K, Suzuki J, Nagata S. Constitutive exposure of phosphatidylserine on viable cells. Proc Natl Acad Sci USA. 2011; 108: 19246-19251.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19246-19251
-
-
Segawa, K.1
Suzuki, J.2
Nagata, S.3
-
48
-
-
0034764237
-
Transient expression of phosphatidylserine at cell-cell contact areas is required for myotube formation
-
van den Eijnde SM, van den Hoff MJ, Reutelingsperger CP, van Heerde WL, Henfling ME, Vermeij-Keers C, et al. Transient expression of phosphatidylserine at cell-cell contact areas is required for myotube formation. J Cell Sci. 2001; 114(Pt 20): 3631-3642.
-
(2001)
J Cell Sci
, vol.114
, pp. 3631-3642
-
-
Van Den Eijnde, S.M.1
Van Den Hoff, M.J.2
Reutelingsperger, C.P.3
Van Heerde, W.L.4
Henfling, M.E.5
Vermeij-Keers, C.6
-
49
-
-
0034674421
-
Role of CD47 as a marker of self on red blood cells
-
Oldenborg PA, Zheleznyak A, Fang YF, Lagenaur CF, Gresham HD, Lindberg FP. Role of CD47 as a marker of self on red blood cells. Science. 2000; 288: 2051-2054.
-
(2000)
Science
, vol.288
, pp. 2051-2054
-
-
Oldenborg, P.A.1
Zheleznyak, A.2
Fang, Y.F.3
Lagenaur, C.F.4
Gresham, H.D.5
Lindberg, F.P.6
-
50
-
-
27744503953
-
CD46 plays a key role in tailoring innate immune recognition of apoptotic, and necrotic cells
-
Elward K, Griffiths M, Mizuno M, Harris CL, Neal JW, Morgan BP, et al. CD46 plays a key role in tailoring innate immune recognition of apoptotic, and necrotic cells. J Biol Chem. 2005; 280: 36342-36354.
-
(2005)
J Biol Chem
, vol.280
, pp. 36342-36354
-
-
Elward, K.1
Griffiths, M.2
Mizuno, M.3
Harris, C.L.4
Neal, J.W.5
Morgan, B.P.6
-
52
-
-
35649024275
-
Ulcerative colitis, and autoimmunity induced by loss of myeloid alphav integrins
-
Lacy-Hulbert A, Smith AM, Tissire H, Barry M, Crowley D, Bronson RT, et al. Ulcerative colitis, and autoimmunity induced by loss of myeloid alphav integrins. Proc Natl Acad Sci USA. 2007; 104: 15823-15828.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15823-15828
-
-
Lacy-Hulbert, A.1
Smith, A.M.2
Tissire, H.3
Barry, M.4
Crowley, D.5
Bronson, R.T.6
-
53
-
-
0036645294
-
Delayed apoptotic cell clearance, and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase
-
Cohen PL, Caricchio R, Abraham V, Camenisch TD, Jennette JC, Roubey RA, et al. Delayed apoptotic cell clearance, and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase. J Exp Med. 2002; 196: 135-140.
-
(2002)
J Exp Med
, vol.196
, pp. 135-140
-
-
Cohen, P.L.1
Caricchio, R.2
Abraham, V.3
Camenisch, T.D.4
Jennette, J.C.5
Roubey, R.A.6
-
54
-
-
0035338504
-
Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: Role of proteases
-
Fadok VA, Bratton DL, Guthrie L, Henson PM. Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteases. J Immunol. 2001; 166: 6847-6854.
-
(2001)
J Immunol
, vol.166
, pp. 6847-6854
-
-
Fadok, V.A.1
Bratton, D.L.2
Guthrie, L.3
Henson, P.M.4
-
55
-
-
80054825045
-
Microtubuleassociated protein 1 light chain 3 alpha (LC3)-Associated phagocytosis is required for the efficient clearance of dead cells
-
Martinez J, Almendinger J, Oberst A, Ness R, Dillon CP, Fitzgerald P, et al. Microtubuleassociated protein 1 light chain 3 alpha (LC3)-Associated phagocytosis is required for the efficient clearance of dead cells. Proc Natl Acad Sci USA. 2011; 108: 17396-17401.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17396-17401
-
-
Martinez, J.1
Almendinger, J.2
Oberst, A.3
Ness, R.4
Dillon, C.P.5
Fitzgerald, P.6
-
56
-
-
40849135716
-
Apoptotic mechanisms involved in neurodegenerative diseases: Experimental, and therapeutic approaches
-
Camins A, Pallas M, Silvestre JS. Apoptotic mechanisms involved in neurodegenerative diseases: experimental, and therapeutic approaches. Methods Find Exp Clin Pharmacol. 2008; 30: 43-65.
-
(2008)
Methods Find Exp Clin Pharmacol
, vol.30
, pp. 43-65
-
-
Camins, A.1
Pallas, M.2
Silvestre, J.S.3
-
57
-
-
80054090725
-
Molecular targeting of atherosclerotic plaques by a stabilin-2-specific peptide ligand
-
Lee GY, Kim JH, Oh GT, Lee BH, Kwon IC, Kim IS. Molecular targeting of atherosclerotic plaques by a stabilin-2-specific peptide ligand . J Control Release. 2011; 155: 211-217.
-
(2011)
J Control Release
, vol.155
, pp. 211-217
-
-
Lee, G.Y.1
Kim, J.H.2
Oh, G.T.3
Lee, B.H.4
Kwon, I.C.5
Kim, I.S.6
-
58
-
-
79953657142
-
Phagocytic clearance in neurodegeneration
-
Sokolowski JD, Mandell JW. Phagocytic clearance in neurodegeneration. Am J Pathol. 2011; 178: 1416-1428.
-
(2011)
Am J Pathol
, vol.178
, pp. 1416-1428
-
-
Sokolowski, J.D.1
Mandell, J.W.2
-
59
-
-
0033625871
-
Alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells
-
Albert ML, Kim JI, Birge RB. alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat Cell Biol. 2000; 2: 899-905.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 899-905
-
-
Albert, M.L.1
Kim, J.I.2
Birge, R.B.3
-
60
-
-
14644411712
-
A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells
-
Wu Y, Singh S, Georgescu MM, Birge RB A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells. J Cell Sci. 2005; 118(Pt 3): 539-553.
-
(2005)
J Cell Sci
, vol.118
, pp. 539-553
-
-
Wu, Y.1
Singh, S.2
Georgescu, M.M.3
Birge, R.B.4
-
61
-
-
44749083712
-
Requirement of adaptor protein GULP during stabilin-2-mediated cell corpse engulfment
-
Park SY, Kang KB, Thapa N, Kim SY, Lee SJ, Kim IS. Requirement of adaptor protein GULP during stabilin-2-mediated cell corpse engulfment. J Biol Chem. 2008; 283: 10593-10600.
-
(2008)
J Biol Chem
, vol.283
, pp. 10593-10600
-
-
Park, S.Y.1
Kang, K.B.2
Thapa, N.3
Kim, S.Y.4
Lee, S.J.5
Kim, I.S.6
-
63
-
-
0037023693
-
Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1, and CD91/low density lipoprotein receptor-related protein (LRP
-
Su HP, Nakada-Tsukui K, Tosello-Trampont AC, Li Y, Bu G, Henson PM, et al. Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1, and CD91/low density lipoprotein receptor-related protein (LRP). J Biol Chem. 2002; 277: 11772-11779.
-
(2002)
J Biol Chem
, vol.277
, pp. 11772-11779
-
-
Su, H.P.1
Nakada-Tsukui, K.2
Tosello-Trampont, A.C.3
Li, Y.4
Bu, G.5
Henson, P.M.6
-
64
-
-
60349123136
-
The phosphatidylserine receptor TIM-4 does not mediate direct signaling
-
Park D, Hochreiter-Hufford A, Ravichandran KS. The phosphatidylserine receptor TIM-4 does not mediate direct signaling. Curr Biol. 2009; 19: 346-351.
-
(2009)
Curr Biol
, vol.19
, pp. 346-351
-
-
Park, D.1
Hochreiter-Hufford, A.2
Ravichandran, K.S.3
-
65
-
-
0038024241
-
Rocks: Multifunctional kinases in cell behaviour
-
Riento K, Ridley AJ. Rocks: multifunctional kinases in cell behaviour. Nat Revi Mol Cell Biol. 2003; 4: 446-456.
-
(2003)
Nat Revi Mol Cell Biol
, vol.4
, pp. 446-456
-
-
Riento, K.1
Ridley, A.J.2
-
66
-
-
0037143448
-
Rho-kinase, and myosin-II control phagocytic cup formation during CR, but not FcgammaR, phagocytosis
-
Olazabal IM, Caron E, May RC, Schilling K, Knecht DA, Machesky LM. Rho-kinase, and myosin-II control phagocytic cup formation during CR, but not FcgammaR, phagocytosis. Curr Biol. 2002; 12: 1413-1418.
-
(2002)
Curr Biol
, vol.12
, pp. 1413-1418
-
-
Olazabal, I.M.1
Caron, E.2
May, R.C.3
Schilling, K.4
Knecht, D.A.5
Machesky, L.M.6
-
67
-
-
33646828766
-
Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages
-
Nakaya M, Tanaka M, Okabe Y, Hanayama R, Nagata S. Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages. J Biol Chem. 2006; 281: 8836-8842.
-
(2006)
J Biol Chem
, vol.281
, pp. 8836-8842
-
-
Nakaya, M.1
Tanaka, M.2
Okabe, Y.3
Hanayama, R.4
Nagata, S.5
-
68
-
-
0036045768
-
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex
-
Brugnera E, Haney L, Grimsley C, Lu M, Walk SF, Tosello-Trampont AC, et al. Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol. 2002; 4: 574-582.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 574-582
-
-
Brugnera, E.1
Haney, L.2
Grimsley, C.3
Lu, M.4
Walk, S.F.5
Tosello-Trampont, A.C.6
-
69
-
-
0032403083
-
WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac
-
Miki H, Suetsugu S, Takenawa T. WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J. 1998; 17: 6932-6941.
-
(1998)
EMBO J.
, vol.17
, pp. 6932-6941
-
-
Miki, H.1
Suetsugu, S.2
Takenawa, T.3
-
70
-
-
0033832788
-
Membrane recruitment of Rac1 triggers phagocytosis
-
Castellano F, Montcourrier P, Chavrier P. Membrane recruitment of Rac1 triggers phagocytosis. J Cell Sci. 2000; 113(Pt 17): 2955-2961.
-
(2000)
J Cell Sci
, vol.113
, pp. 2955-2961
-
-
Castellano, F.1
Montcourrier, P.2
Chavrier, P.3
-
71
-
-
0035871703
-
Cutting edge: The Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells
-
Leverrier Y, Lorenzi R, Blundell MP, Brickell P, Kinnon C, Ridley AJ, et al. Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells. J Immunol. 2001; 166: 4831-4834.
-
(2001)
J Immunol
, vol.166
, pp. 4831-4834
-
-
Leverrier, Y.1
Lorenzi, R.2
Blundell, M.P.3
Brickell, P.4
Kinnon, C.5
Ridley, A.J.6
-
72
-
-
33750465224
-
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
-
Kawane K, Ohtani M, Miwa K, Kizawa T, Kanbara Y, Yoshioka Y, et al. Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages. Nature. 2006; 443: 998-1002.
-
(2006)
Nature
, vol.443
, pp. 998-1002
-
-
Kawane, K.1
Ohtani, M.2
Miwa, K.3
Kizawa, T.4
Kanbara, Y.5
Yoshioka, Y.6
-
73
-
-
84878793136
-
The relationship between metabolism, and the autophagy machinery during the innate immune response
-
Martinez J, Verbist K, Wang R, Green DR. The relationship between metabolism, and the autophagy machinery during the innate immune response. Cell Metab. 2013; 17: 895-900.
-
(2013)
Cell Metab
, vol.17
, pp. 895-900
-
-
Martinez, J.1
Verbist, K.2
Wang, R.3
Green, D.R.4
-
74
-
-
84934287492
-
Molecular characterization of LC3-Associated phagocytosis (LAP) reveals distinct roles for Rubicon NOX2 and autophagy proteins
-
Martinez J, Malireddi RK, Lu Q, Cunha LD, Pelletier S, Gingras S, et al. Molecular characterization of LC3-Associated phagocytosis (LAP) reveals distinct roles for Rubicon, NOX2, and autophagy proteins. Nat Cell Biol. 2015; 17: 893-906.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 893-906
-
-
Martinez, J.1
Malireddi, R.K.2
Lu, Q.3
Cunha, L.D.4
Pelletier, S.5
Gingras, S.6
-
75
-
-
84870861513
-
Noncanonical autophagy is required for type i interferon secretion in response to DNA-immune complexes
-
Henault J, Martinez J, Riggs JM, Tian J, Mehta P, Clarke L, et al. Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. Immunity. 2012; 37: 986-997.
-
(2012)
Immunity
, vol.37
, pp. 986-997
-
-
Henault, J.1
Martinez, J.2
Riggs, J.M.3
Tian, J.4
Mehta, P.5
Clarke, L.6
-
76
-
-
80455122654
-
Autophagy machinery mediates macroendocytic processing, and entotic cell death by targeting single membranes
-
Florey O, Kim SE, Sandoval CP, Haynes CM, Overholtzer M. Autophagy machinery mediates macroendocytic processing, and entotic cell death by targeting single membranes. Nat Cell Biol. 2011; 13: 1335-1343.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1335-1343
-
-
Florey, O.1
Kim, S.E.2
Sandoval, C.P.3
Haynes, C.M.4
Overholtzer, M.5
-
77
-
-
37549043217
-
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
-
Sanjuan MA, Dillon CP, Tait SW, Moshiach S, Dorsey F, Connell S, et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature. 2007; 450: 1253-1257.
-
(2007)
Nature
, vol.450
, pp. 1253-1257
-
-
Sanjuan, M.A.1
Dillon, C.P.2
Tait, S.W.3
Moshiach, S.4
Dorsey, F.5
Connell, S.6
-
78
-
-
84934287492
-
Molecular characterization of LC3-Associated phagocytosis reveals distinct roles for Rubicon NOX2 and autophagy proteins
-
Martinez J, Malireddi RK, Lu Q, Cunha LD, Pelletier S, Gingras S, et al. Molecular characterization of LC3-Associated phagocytosis reveals distinct roles for Rubicon, NOX2, and autophagy proteins. Nat Cell Biol. 2015; 17: 893-906.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 893-906
-
-
Martinez, J.1
Malireddi, R.K.2
Lu, Q.3
Cunha, L.D.4
Pelletier, S.5
Gingras, S.6
-
80
-
-
34347344990
-
Ambra1 regulates autophagy, and development of the nervous system
-
Fimia GM, Stoykova A, Romagnoli A, Giunta L, Di Bartolomeo S, Nardacci R, et al. Ambra1 regulates autophagy, and development of the nervous system. Nature. 2007; 447: 1121-1125.
-
(2007)
Nature
, vol.447
, pp. 1121-1125
-
-
Fimia, G.M.1
Stoykova, A.2
Romagnoli, A.3
Giunta, L.4
Di Bartolomeo, S.5
Nardacci, R.6
-
81
-
-
77953726483
-
Mammalian Atg18 (WIPI2) localizes to omegasome-Anchored phagophores, and positively regulates LC3 lipidation
-
Polson HE, de Lartigue J, Rigden DJ, Reedijk M, Urbe S, Clague MJ, et al. Mammalian Atg18 (WIPI2) localizes to omegasome-Anchored phagophores, and positively regulates LC3 lipidation. Autophagy. 2010; 6: 506-522.
-
(2010)
Autophagy
, vol.6
, pp. 506-522
-
-
Polson, H.E.1
De Lartigue, J.2
Rigden, D.J.3
Reedijk, M.4
Urbe, S.5
Clague, M.J.6
-
82
-
-
34548700796
-
Unveiling the roles of autophagy in innate, and adaptive immunity
-
Levine B, Deretic V. Unveiling the roles of autophagy in innate, and adaptive immunity. Nat Rev Immunol. 2007; 7: 767-777.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
83
-
-
59249089394
-
Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14, and UVRAG
-
Itakura E, Kishi C, Inoue K, Mizushima N. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14, and UVRAG. Mol Biol Cell. 2008; 19: 5360-5372.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 5360-5372
-
-
Itakura, E.1
Kishi, C.2
Inoue, K.3
Mizushima, N.4
-
84
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L, and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, et al. Distinct regulation of autophagic activity by Atg14L, and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol. 2009; 11: 468-476.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
Wang, Q.J.2
Li, X.3
Yan, Y.4
Backer, J.M.5
Chait, B.T.6
-
85
-
-
84891370240
-
Essential role for UVRAG in autophagy, and maintenance of cardiac function
-
Song Z, An L, Ye Y, Wu J, Zou Y, He L, et al. Essential role for UVRAG in autophagy, and maintenance of cardiac function. Cardiovasc Res. 2014; 101: 48-56.
-
(2014)
Cardiovasc Res
, vol.101
, pp. 48-56
-
-
Song, Z.1
An, L.2
Ye, Y.3
Wu, J.4
Zou, Y.5
He, L.6
-
86
-
-
64049086758
-
Two Beclin 1-binding proteins, Atg14L, and Rubicon, reciprocally regulate autophagy at different stages
-
Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, et al. Two Beclin 1-binding proteins, Atg14L, and Rubicon, reciprocally regulate autophagy at different stages. Nat Cell Biol. 2009; 11: 385-396.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 385-396
-
-
Matsunaga, K.1
Saitoh, T.2
Tabata, K.3
Omori, H.4
Satoh, T.5
Kurotori, N.6
-
87
-
-
78650600158
-
Rubicon controls endosome maturation as a Rab7 effector
-
Sun Q, Westphal W, Wong KN, Tan I, Zhong Q. Rubicon controls endosome maturation as a Rab7 effector. Proc Natl Acad Sci USA. 2010; 107: 19338-19343.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 19338-19343
-
-
Sun, Q.1
Westphal, W.2
Wong, K.N.3
Tan, I.4
Zhong, Q.5
-
88
-
-
84863373173
-
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation
-
Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, et al. Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation. Cell Host Microbe. 2012; 11: 264-276.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 264-276
-
-
Yang, C.S.1
Lee, J.S.2
Rodgers, M.3
Min, C.K.4
Lee, J.Y.5
Kim, H.J.6
-
89
-
-
78650936005
-
The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression
-
Sun Q, Zhang J, Fan W, Wong KN, Ding X, Chen S, et al. The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppression. J Biol Chem. 2011; 286: 185-191.
-
(2011)
J Biol Chem
, vol.286
, pp. 185-191
-
-
Sun, Q.1
Zhang, J.2
Fan, W.3
Wong, K.N.4
Ding, X.5
Chen, S.6
-
90
-
-
81755171486
-
Cooperation of p40(phox) with p47(phox) for Nox2-based NADPH oxidase activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis: Mechanism for acquisition of p40(phox) phosphatidylinositol 3-phosphate (PI(3)P) binding
-
Ueyama T, Nakakita J, Nakamura T, Kobayashi T, Kobayashi T, Son J, et al. Cooperation of p40(phox) with p47(phox) for Nox2-based NADPH oxidase activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis: mechanism for acquisition of p40(phox) phosphatidylinositol 3-phosphate (PI(3)P) binding. J Biol Chem. 2011; 286: 40693-40705.
-
(2011)
J Biol Chem
, vol.286
, pp. 40693-40705
-
-
Ueyama, T.1
Nakakita, J.2
Nakamura, T.3
Kobayashi, T.4
Kobayashi, T.5
Son, J.6
-
91
-
-
65549094988
-
Activation of antibacterial autophagy by NADPH oxidases
-
Huang J, Canadien V, Lam GY, Steinberg BE, Dinauer MC, Magalhaes MA, et al. Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci USA. 2009; 106: 6226-6231.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6226-6231
-
-
Huang, J.1
Canadien, V.2
Lam, G.Y.3
Steinberg, B.E.4
Dinauer, M.C.5
Magalhaes, M.A.6
-
92
-
-
84455200568
-
Metabolic connections during apoptotic cell engulfment
-
Han CZ, Ravichandran KS. Metabolic connections during apoptotic cell engulfment. Cell. 2011; 147: 1442-1445.
-
(2011)
Cell
, vol.147
, pp. 1442-1445
-
-
Han, C.Z.1
Ravichandran, K.S.2
-
93
-
-
8444251663
-
Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells
-
Kim S, Elkon KB, Ma X. Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells. Immunity. 2004; 21: 643-653.
-
(2004)
Immunity
, vol.21
, pp. 643-653
-
-
Kim, S.1
Elkon, K.B.2
Ma, X.3
-
94
-
-
68949145931
-
Apoptotic cells promote their own clearance, and immune tolerance through activation of the nuclear receptor LXR
-
A-Gonzalez N, Bensinger SJ, Hong C, Beceiro S, Bradley MN, Zelcer N, et al. Apoptotic cells promote their own clearance, and immune tolerance through activation of the nuclear receptor LXR. Immunity. 2009; 31: 245-258.
-
(2009)
Immunity
, vol.31
, pp. 245-258
-
-
A-Gonzalez, N.1
Bensinger, S.J.2
Hong, C.3
Beceiro, S.4
Bradley, M.N.5
Zelcer, N.6
-
95
-
-
79251561239
-
Autoimmune kidney disease, and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-Activated receptor gamma or retinoid X receptor alpha deficiency
-
Roszer T, Menendez-Gutierrez MP, Lefterova MI, Alameda D, Nunez V, Lazar MA, et al. Autoimmune kidney disease, and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-Activated receptor gamma or retinoid X receptor alpha deficiency. J Immunol. 2011; 186: 621-631.
-
(2011)
J Immunol
, vol.186
, pp. 621-631
-
-
Roszer, T.1
Menendez-Gutierrez, M.P.2
Lefterova, M.I.3
Alameda, D.4
Nunez, V.5
Lazar, M.A.6
-
96
-
-
70449094641
-
PPAR-delta senses, and orchestrates clearance of apoptotic cells to promote tolerance
-
Mukundan L, Odegaard JI, Morel CR, Heredia JE, Mwangi JW, Ricardo-Gonzalez RR, et al. PPAR-delta senses, and orchestrates clearance of apoptotic cells to promote tolerance. Nat Med. 2009; 15: 1266-1272.
-
(2009)
Nat Med
, vol.15
, pp. 1266-1272
-
-
Mukundan, L.1
Odegaard, J.I.2
Morel, C.R.3
Heredia, J.E.4
Mwangi, J.W.5
Ricardo-Gonzalez, R.R.6
-
97
-
-
33750957975
-
Apoptotic cells induce a phosphatidylserine-dependent homeostatic response from phagocytes
-
Kiss RS, Elliott MR, Ma Z, Marcel YL, Ravichandran KS. Apoptotic cells induce a phosphatidylserine-dependent homeostatic response from phagocytes. Curr Biol. 2006; 16: 2252-2258.
-
(2006)
Curr Biol
, vol.16
, pp. 2252-2258
-
-
Kiss, R.S.1
Elliott, M.R.2
Ma, Z.3
Marcel, Y.L.4
Ravichandran, K.S.5
-
98
-
-
0036143018
-
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion, and the resolution of inflammation
-
Huynh ML, Fadok VA, Henson PM. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion, and the resolution of inflammation. J Clin Invest. 2002; 109: 41-50.
-
(2002)
J Clin Invest
, vol.109
, pp. 41-50
-
-
Huynh, M.L.1
Fadok, V.A.2
Henson, P.M.3
-
99
-
-
70549107710
-
Mitochondrial cell death effectors
-
Brenner D, Mak TW. Mitochondrial cell death effectors. Curr Opin Cell Biol. 2009; 21: 871-877.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 871-877
-
-
Brenner, D.1
Mak, T.W.2
-
100
-
-
77956095537
-
Mitochondria, and cell death: Outer membrane permeabilization, and beyond
-
Tait SW, Green DR. Mitochondria, and cell death: outer membrane permeabilization, and beyond. Nat Rev Mol Cell Biol. 2010; 11: 621-632.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
101
-
-
81355146366
-
A unified model of mammalian BCL-2 protein family interactions at the mitochondria
-
Llambi F, Moldoveanu T, Tait SW, Bouchier-Hayes L, Temirov J, McCormick LL, et al A unified model of mammalian BCL-2 protein family interactions at the mitochondria. Mol Cell. 2011; 44: 517-531.
-
(2011)
Mol Cell
, vol.44
, pp. 517-531
-
-
Llambi, F.1
Moldoveanu, T.2
Tait, S.W.3
Bouchier-Hayes, L.4
Temirov, J.5
McCormick, L.L.6
-
102
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright KM, Renatus M, Scott FL, Sperandio S, Shin H, Pedersen IM, et al A unified model for apical caspase activation. Mol Cell. 2003; 11: 529-541.
-
(2003)
Mol Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
-
103
-
-
67349124914
-
Immunogenic, and tolerogenic cell death
-
Green DR, Ferguson T, Zitvogel L, Kroemer G. Immunogenic, and tolerogenic cell death. Nat Rev Immunol. 2009; 9: 353-363.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 353-363
-
-
Green, D.R.1
Ferguson, T.2
Zitvogel, L.3
Kroemer, G.4
-
104
-
-
84887623828
-
Crosstalk between apoptosis, necrosis, and autophagy
-
Nikoletopoulou V, Markaki M, Palikaras K, Tavernarakis N. Crosstalk between apoptosis, necrosis, and autophagy. Biochim Biophys acta. 2013; 1833: 3448-3459.
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 3448-3459
-
-
Nikoletopoulou, V.1
Markaki, M.2
Palikaras, K.3
Tavernarakis, N.4
-
105
-
-
0035433420
-
Four deaths, and a funeral: From caspases to alternative mechanisms
-
Leist M, Jaattela M. Four deaths, and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol. 2001; 2: 589-598.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
106
-
-
41149118513
-
How dying cells alert the immune system to danger
-
Kono H, Rock KL. How dying cells alert the immune system to danger. Nat Rev Immunol. 2008; 8: 279-289.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
107
-
-
84912086649
-
The two faces of receptor interacting protein kinase-1
-
Weinlich R, Green DR. The two faces of receptor interacting protein kinase-1. Mol Cell. 2014; 56: 469-480.
-
(2014)
Mol Cell
, vol.56
, pp. 469-480
-
-
Weinlich, R.1
Green, D.R.2
-
108
-
-
33645784245
-
Genetic disorders of programmed cell death in the immune system
-
Bidere N, Su HC, Lenardo MJ. Genetic disorders of programmed cell death in the immune system. Ann Revi Immunol. 2006; 24: 321-352.
-
(2006)
Ann Revi Immunol
, vol.24
, pp. 321-352
-
-
Bidere, N.1
Su, H.C.2
Lenardo, M.J.3
-
109
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser WJ, Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer LP, Hakem R, et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature. 2011; 471: 368-372.
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
-
110
-
-
79960922705
-
CIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova M, Geserick P, Kellert B, Dimitrova DP, Langlais C, Hupe M, et al. cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell. 2011; 43: 449-463.
-
(2011)
Mol Cell
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
Dimitrova, D.P.4
Langlais, C.5
Hupe, M.6
-
111
-
-
84929512041
-
RIPK1, and RIPK3: Critical regulators of inflammation, and cell death
-
Newton K. RIPK1, and RIPK3: critical regulators of inflammation, and cell death. Trends Cell Biol. 2015; 25: 347-353.
-
(2015)
Trends Cell Biol
, vol.25
, pp. 347-353
-
-
Newton, K.1
-
112
-
-
84949537573
-
Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis
-
Rodriguez DA, Weinlich R, Brown S, Guy C, Fitzgerald P, Dillon CP, et al. Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis. Cell Death Differ. 2015; 23: 76-88.
-
(2015)
Cell Death Differ
, vol.23
, pp. 76-88
-
-
Rodriguez, D.A.1
Weinlich, R.2
Brown, S.3
Guy, C.4
Fitzgerald, P.5
Dillon, C.P.6
-
113
-
-
84892896075
-
Burning down the house: Cellular actions during pyroptosis
-
LaRock CN, Cookson BT. Burning down the house: cellular actions during pyroptosis. PLoS Pathog. 2013; 9: e1003793.
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003793
-
-
LaRock, C.N.1
Cookson, B.T.2
-
114
-
-
84927745897
-
Pyroptotic cell death defends against intracellular pathogens
-
Jorgensen I, Miao EA. Pyroptotic cell death defends against intracellular pathogens. Immunol Rev. 2015; 265: 130-142.
-
(2015)
Immunol Rev
, vol.265
, pp. 130-142
-
-
Jorgensen, I.1
Miao, E.A.2
-
115
-
-
34548398189
-
P2X 7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes, and ameliorates experimental autoimmune encephalomyelitis
-
Matute C, Torre I, Perez-Cerda F, Perez-Samartin A, Alberdi E, Etxebarria E, et al. P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes, and ameliorates experimental autoimmune encephalomyelitis. J Neurosci. 2007; 27: 9525-9533.
-
(2007)
J Neurosci
, vol.27
, pp. 9525-9533
-
-
Matute, C.1
Torre, I.2
Perez-Cerda, F.3
Perez-Samartin, A.4
Alberdi, E.5
Etxebarria, E.6
-
116
-
-
84879256660
-
Contribution of pannexin1 to experimental autoimmune encephalomyelitis
-
Lutz SE, Gonzalez-Fernandez E, Ventura JC, Perez-Samartin A, Tarassishin L, Negoro H, et al. Contribution of pannexin1 to experimental autoimmune encephalomyelitis. PloS ONE. 2013; 8: e66657.
-
(2013)
PloS ONE
, vol.8
, pp. e66657
-
-
Lutz, S.E.1
Gonzalez-Fernandez, E.2
Ventura, J.C.3
Perez-Samartin, A.4
Tarassishin, L.5
Negoro, H.6
-
117
-
-
79955491175
-
The P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptor-mediated seizure susceptibility in mice
-
Kim JE, Kang TC. The P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptor-mediated seizure susceptibility in mice. J Clin Invest. 2011; 121: 2037-2047.
-
(2011)
J Clin Invest
, vol.121
, pp. 2037-2047
-
-
Kim, J.E.1
Kang, T.C.2
-
118
-
-
84886721875
-
Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation
-
Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, et al. Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nat Immunol. 2013; 14: 1166-1172.
-
(2013)
Nat Immunol
, vol.14
, pp. 1166-1172
-
-
Garris, C.S.1
Wu, L.2
Acharya, S.3
Arac, A.4
Blaho, V.A.5
Huang, Y.6
-
119
-
-
37549004312
-
Role of lysophosphatidylcholine (LPC) in atherosclerosis
-
Matsumoto T, Kobayashi T, Kamata K. Role of lysophosphatidylcholine (LPC) in atherosclerosis. Curr Med Chem. 2007; 14: 3209-3220.
-
(2007)
Curr Med Chem
, vol.14
, pp. 3209-3220
-
-
Matsumoto, T.1
Kobayashi, T.2
Kamata, K.3
-
120
-
-
0035020493
-
Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome
-
Le LQ, Kabarowski JH, Weng Z, Satterthwaite AB, Harvill ET, Jensen ER, et al. Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome. Immunity. 2001; 14: 561-571.
-
(2001)
Immunity
, vol.14
, pp. 561-571
-
-
Le, L.Q.1
Kabarowski, J.H.2
Weng, Z.3
Satterthwaite, A.B.4
Harvill, E.T.5
Jensen, E.R.6
-
121
-
-
61949448303
-
G2A deficiency in mice promotes macrophage activation, and atherosclerosis
-
Bolick DT, Skaflen MD, Johnson LE, Kwon SC, Howatt D, Daugherty A, et al. G2A deficiency in mice promotes macrophage activation, and atherosclerosis. Circ Res. 2009; 104: 318-327.
-
(2009)
Circ Res
, vol.104
, pp. 318-327
-
-
Bolick, D.T.1
Skaflen, M.D.2
Johnson, L.E.3
Kwon, S.C.4
Howatt, D.5
Daugherty, A.6
-
122
-
-
68249095210
-
CX3CR1-deficiency is associated with increased severity of disease in experimental autoimmune uveitis
-
Dagkalis A, Wallace C, Hing B, Liversidge J, Crane IJ. CX3CR1-deficiency is associated with increased severity of disease in experimental autoimmune uveitis. Immunology. 2009; 128: 25-33.
-
(2009)
Immunology
, vol.128
, pp. 25-33
-
-
Dagkalis, A.1
Wallace, C.2
Hing, B.3
Liversidge, J.4
Crane, I.J.5
-
123
-
-
0034235306
-
The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia
-
Boehme SA, Lio FM, Maciejewski-Lenoir D, Bacon KB, Conlon PJ. The chemokine fractalkine inhibits Fas-mediated cell death of brain microglia. J Immunol. 2000; 165: 397-403.
-
(2000)
J Immunol
, vol.165
, pp. 397-403
-
-
Boehme, S.A.1
Lio, F.M.2
Maciejewski-Lenoir, D.3
Bacon, K.B.4
Conlon, P.J.5
-
124
-
-
0028830668
-
Circulating forms of icam-3 (cicam-3) elevated levels in autoimmune diseases, and lack of association with cicam-1
-
Martin S, Rieckmann P, Melchers I, Wagner R, Bertrams J, Voskuyl AE, et al. Circulating forms of ICAM-3 (cICAM-3). Elevated levels in autoimmune diseases, and lack of association with cICAM-1. J Immunol. 1995; 154: 1951-1955.
-
(1995)
J Immunol
, vol.154
, pp. 1951-1955
-
-
Martin, S.1
Rieckmann, P.2
Melchers, I.3
Wagner, R.4
Bertrams, J.5
Voskuyl, A.E.6
-
125
-
-
32744460953
-
Calreticulins role(s) in autoimmune disorders
-
Eggleton P, Michalak M (eds Chap 17. Springer: New York City, NY, USA
-
Sontheimer R, Racila D, Racila E, Eggleton P, Donnelly S. Calreticulins role(s) in autoimmune disorders. In: Eggleton P, Michalak M (eds). Calreticulin Molecular Biology Intelligence Unit, Chap 17. Springer: New York City, NY, USA, 2003, pp 180-192.
-
(2003)
Calreticulin Molecular Biology Intelligence Unit
, pp. 180-192
-
-
Sontheimer, R.1
Racila, D.2
Racila, E.3
Eggleton, P.4
Donnelly, S.5
-
126
-
-
0035849176
-
Complement. Second of two parts
-
Walport MJ. Complement. Second of two parts. N Engl J Med. 2001; 344: 1140-1144.
-
(2001)
N Engl J Med
, vol.344
, pp. 1140-1144
-
-
Walport, M.J.1
-
127
-
-
84864373441
-
Defect in regulatory B-cell function, and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice
-
Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, et al. Defect in regulatory B-cell function, and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice. Proc Natl Acad Sci USA. 2012; 109: 12105-12110.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 12105-12110
-
-
Xiao, S.1
Brooks, C.R.2
Zhu, C.3
Wu, C.4
Sweere, J.M.5
Petecka, S.6
-
128
-
-
0035204919
-
Identification of Tapr (an airway hyperreactivity regulatory locus), and the linked Tim gene family
-
McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, et al. Identification of Tapr (an airway hyperreactivity regulatory locus), and the linked Tim gene family. Nat Immunol. 2001; 2: 1109-1116.
-
(2001)
Nat Immunol
, vol.2
, pp. 1109-1116
-
-
McIntire, J.J.1
Umetsu, S.E.2
Akbari, O.3
Potter, M.4
Kuchroo, V.K.5
Barsh, G.S.6
-
129
-
-
84926352081
-
BAI1 regulates spatial learning, and synaptic plasticity in the hippocampus
-
Zhu D, Li C, Swanson AM, Villalba RM, Guo J, Zhang Z, et al. BAI1 regulates spatial learning, and synaptic plasticity in the hippocampus. J Clin Invest. 2015; 125: 1497-1508.
-
(2015)
J Clin Invest
, vol.125
, pp. 1497-1508
-
-
Zhu, D.1
Li, C.2
Swanson, A.M.3
Villalba, R.M.4
Guo, J.5
Zhang, Z.6
-
130
-
-
84887408112
-
Integrinmodulating therapy prevents fibrosis, and autoimmunity in mouse models of scleroderma
-
Gerber EE, Gallo EM, Fontana SC, Davis EC, Wigley FM, Huso DL, et al. Integrinmodulating therapy prevents fibrosis, and autoimmunity in mouse models of scleroderma. Nature. 2013; 503: 126-130.
-
(2013)
Nature
, vol.503
, pp. 126-130
-
-
Gerber, E.E.1
Gallo, E.M.2
Fontana, S.C.3
Davis, E.C.4
Wigley, F.M.5
Huso, D.L.6
-
131
-
-
0033757463
-
Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa
-
Gal A, Li Y, Thompson DA, Weir J, Orth U, Jacobson SG, et al. Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet. 2000; 26: 270-271.
-
(2000)
Nat Genet
, vol.26
, pp. 270-271
-
-
Gal, A.1
Li, Y.2
Thompson, D.A.3
Weir, J.4
Orth, U.5
Jacobson, S.G.6
-
132
-
-
52449109523
-
Mertk receptor mutation reduces efferocytosis efficiency, and promotes apoptotic cell accumulation, and plaque necrosis in atherosclerotic lesions of apoe-/- mice
-
Thorp E, Cui D, Schrijvers DM, Kuriakose G, Tabas I. Mertk receptor mutation reduces efferocytosis efficiency, and promotes apoptotic cell accumulation, and plaque necrosis in atherosclerotic lesions of apoe-/- mice. Arterioscler Thromb Vasc Biol. 2008; 28: 1421-1428.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1421-1428
-
-
Thorp, E.1
Cui, D.2
Schrijvers, D.M.3
Kuriakose, G.4
Tabas, I.5
-
133
-
-
34247524090
-
Lactadherin deficiency leads to apoptotic cell accumulation, and accelerated atherosclerosis in mice
-
Ait-Oufella H, Kinugawa K, Zoll J, Simon T, Boddaert J, Heeneman S, et al. Lactadherin deficiency leads to apoptotic cell accumulation, and accelerated atherosclerosis in mice. Circulation. 2007; 115: 2168-2177.
-
(2007)
Circulation
, vol.115
, pp. 2168-2177
-
-
Ait-Oufella, H.1
Kinugawa, K.2
Zoll, J.3
Simon, T.4
Boddaert, J.5
Heeneman, S.6
-
134
-
-
0023227876
-
Hereditary protein S deficiency: Clinical manifestations
-
Engesser L, Broekmans AW, Briet E, Brommer EJ, Bertina RM. Hereditary protein S deficiency: clinical manifestations. Ann Intern Med. 1987; 106: 677-682.
-
(1987)
Ann Intern Med
, vol.106
, pp. 677-682
-
-
Engesser, L.1
Broekmans, A.W.2
Briet, E.3
Brommer, E.J.4
Bertina, R.M.5
-
135
-
-
77954554268
-
TAM receptor ligand s in lupus: Protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus
-
Suh CH, Hilliard B, Li S, Merrill JT, Cohen PL. TAM receptor ligand s in lupus: protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus. Arthritis Res Ther. 2010; 12: R146.
-
(2010)
Arthritis Res Ther
, vol.12
, pp. R146
-
-
Suh, C.H.1
Hilliard, B.2
Li, S.3
Merrill, J.T.4
Cohen, P.L.5
-
136
-
-
84907376415
-
P85alpha recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression
-
Tian L, Choi SC, Murakami Y, Allen J, Morse HC 3rd, Qi CF, et al. p85alpha recruitment by the CD300f phosphatidylserine receptor mediates apoptotic cell clearance required for autoimmunity suppression. Nat Commun. 2014; 5: 3146.
-
(2014)
Nat Commun
, vol.5
, pp. 3146
-
-
Tian, L.1
Choi, S.C.2
Murakami, Y.3
Allen, J.4
Morse, H.C.5
Qi, C.F.6
-
137
-
-
80052494062
-
Phagocytic activity of neuronal progenitors regulates adult neurogenesis
-
Lu Z, Elliott MR, Chen Y, Walsh JT, Klibanov AL, Ravichandran KS, et al. Phagocytic activity of neuronal progenitors regulates adult neurogenesis. Nat Cell Biol. 2011; 13: 1076-1083.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1076-1083
-
-
Lu, Z.1
Elliott, M.R.2
Chen, Y.3
Walsh, J.T.4
Klibanov, A.L.5
Ravichandran, K.S.6
-
138
-
-
78349310110
-
DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4
-
Sanematsu F, Hirashima M, Laurin M, Takii R, Nishikimi A, Kitajima K, et al. DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4. Circ Res. 2010; 107: 1102-1105.
-
(2010)
Circ Res
, vol.107
, pp. 1102-1105
-
-
Sanematsu, F.1
Hirashima, M.2
Laurin, M.3
Takii, R.4
Nishikimi, A.5
Kitajima, K.6
-
139
-
-
55749114582
-
The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo
-
Laurin M, Fradet N, Blangy A, Hall A, Vuori K, Cote JF. The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. Proc Natl Acad Sci USA. 2008; 105: 15446-15451.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15446-15451
-
-
Laurin, M.1
Fradet, N.2
Blangy, A.3
Hall, A.4
Vuori, K.5
Cote, J.F.6
-
140
-
-
84874604710
-
GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance
-
Nakaya M, Tajima M, Kosako H, Nakaya T, Hashimoto A, Watari K, et al. GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance. Nat Commun. 2013; 4: 1532.
-
(2013)
Nat Commun
, vol.4
, pp. 1532
-
-
Nakaya, M.1
Tajima, M.2
Kosako, H.3
Nakaya, T.4
Hashimoto, A.5
Watari, K.6
-
141
-
-
77955490256
-
A Rac1 inhibitory peptide suppresses antibody production, and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis
-
Abreu JR, Dontje W, Krausz S, de Launay D, van Hennik PB, van Stalborch AM, et al A Rac1 inhibitory peptide suppresses antibody production, and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis. Arthritis Res Ther. 2010; 12: R2.
-
(2010)
Arthritis Res Ther
, vol.12
, pp. R2
-
-
Abreu, J.R.1
Dontje, W.2
Krausz, S.3
De Launay, D.4
Van Hennik, P.B.5
Van Stalborch, A.M.6
-
142
-
-
69449090770
-
Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity
-
Xu J, Wagoner G, Douglas JC, Drew PD. Liver X receptor agonist regulation of Th17 lymphocyte function in autoimmunity. J Leuk Biol. 2009; 86: 401-409.
-
(2009)
J Leuk Biol
, vol.86
, pp. 401-409
-
-
Xu, J.1
Wagoner, G.2
Douglas, J.C.3
Drew, P.D.4
-
143
-
-
79551545978
-
Liver X receptor (LXR) mediates negative regulation of mouse, and human Th17 differentiation
-
Cui G, Qin X, Wu L, Zhang Y, Sheng X, Yu Q, et al. Liver X receptor (LXR) mediates negative regulation of mouse, and human Th17 differentiation. J Clin Invest. 2011; 121: 658-670.
-
(2011)
J Clin Invest
, vol.121
, pp. 658-670
-
-
Cui, G.1
Qin, X.2
Wu, L.3
Zhang, Y.4
Sheng, X.5
Yu, Q.6
-
144
-
-
84855427447
-
Coordinate regulation of neutrophil homeostasis by liver X receptors in mice
-
Hong C, Kidani Y, A-Gonzalez N, Phung T, Ito A, Rong X, et al. Coordinate regulation of neutrophil homeostasis by liver X receptors in mice. J Clin Invest. 2012; 122: 337-347.
-
(2012)
J Clin Invest
, vol.122
, pp. 337-347
-
-
Hong, C.1
Kidani, Y.2
A-Gonzalez, N.3
Phung, T.4
Ito, A.5
Rong, X.6
-
145
-
-
84904057157
-
Liver X receptors alpha gene (NR1H3) promoter polymorphisms are associated with systemic lupus erythematosus in Koreans
-
Jeon JY, Nam JY, Kim HA, Park YB, Bae SC, Suh CH. Liver X receptors alpha gene (NR1H3) promoter polymorphisms are associated with systemic lupus erythematosus in Koreans. Arthritis Res Ther. 2014; 16: R112.
-
(2014)
Arthritis Res Ther
, vol.16
, pp. R112
-
-
Jeon, J.Y.1
Nam, J.Y.2
Kim, H.A.3
Park, Y.B.4
Bae, S.C.5
Suh, C.H.6
-
146
-
-
84899684795
-
Activation of liver X receptor alleviates ocular inflammation in experimental autoimmune uveitis
-
Yang H, Zheng S, Qiu Y, Yang Y, Wang C, Yang P, et al. Activation of liver X receptor alleviates ocular inflammation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2014; 55: 2795-2804.
-
(2014)
Invest Ophthalmol Vis Sci
, vol.55
, pp. 2795-2804
-
-
Yang, H.1
Zheng, S.2
Qiu, Y.3
Yang, Y.4
Wang, C.5
Yang, P.6
-
147
-
-
0037428442
-
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis
-
Cao G, Liang Y, Broderick CL, Oldham BA, Beyer TP, Schmidt RJ, et al. Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis. J Biol Chem. 2003; 278: 1131-1136.
-
(2003)
J Biol Chem
, vol.278
, pp. 1131-1136
-
-
Cao, G.1
Liang, Y.2
Broderick, C.L.3
Oldham, B.A.4
Beyer, T.P.5
Schmidt, R.J.6
-
148
-
-
0037188553
-
Synthetic LXR ligand inhibits the development of atherosclerosis in mice
-
Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, et al. Synthetic LXR ligand inhibits the development of atherosclerosis in mice. Proc Natl Acad Sci USA. 2002; 99: 7604-7609.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7604-7609
-
-
Joseph, S.B.1
McKilligin, E.2
Pei, L.3
Watson, M.A.4
Collins, A.R.5
Laffitte, B.A.6
-
149
-
-
0035132330
-
PPAR-gamma dependent, and independent effects on macrophage-gene expression in lipid metabolism, and inflammation
-
Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM. PPAR-gamma dependent, and independent effects on macrophage-gene expression in lipid metabolism, and inflammation. Nat Med. 2001; 7: 48-52.
-
(2001)
Nat Med
, vol.7
, pp. 48-52
-
-
Chawla, A.1
Barak, Y.2
Nagy, L.3
Liao, D.4
Tontonoz, P.5
Evans, R.M.6
-
150
-
-
23244451031
-
Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6, and lowdensity lipoprotein receptor-deficient mice
-
Babaev VR, Yancey PG, Ryzhov SV, Kon V, Breyer MD, Magnuson MA, et al. Conditional knockout of macrophage PPARgamma increases atherosclerosis in C57BL/6, and lowdensity lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2005; 25: 1647-1653.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1647-1653
-
-
Babaev, V.R.1
Yancey, P.G.2
Ryzhov, S.V.3
Kon, V.4
Breyer, M.D.5
Magnuson, M.A.6
-
151
-
-
84875221357
-
Adult cartilagespecific peroxisome proliferator-Activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype
-
Vasheghani F, Monemdjou R, Fahmi H, Zhang Y, Perez G, Blati M, et al. Adult cartilagespecific peroxisome proliferator-Activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype. Am J Pathol. 2013; 182: 1099-1106.
-
(2013)
Am J Pathol
, vol.182
, pp. 1099-1106
-
-
Vasheghani, F.1
Monemdjou, R.2
Fahmi, H.3
Zhang, Y.4
Perez, G.5
Blati, M.6
-
152
-
-
0034490992
-
Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency
-
Christiansen-Weber TA, Voland JR, Wu Y, Ngo K, Roland BL, Nguyen S, et al. Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency. Am J Pathol. 2000; 157: 1017-1029.
-
(2000)
Am J Pathol
, vol.157
, pp. 1017-1029
-
-
Christiansen-Weber, T.A.1
Voland, J.R.2
Wu, Y.3
Ngo, K.4
Roland, B.L.5
Nguyen, S.6
-
153
-
-
70349568520
-
The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice
-
Tsubota K, Nishiyama T, Mishima K, Inoue H, Doi T, Hattori Y, et al. The role of fractalkine as an accelerating factor on the autoimmune exocrinopathy in mice. Invest Ophthalmol Vis Sci. 2009; 50: 4753-4760.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 4753-4760
-
-
Tsubota, K.1
Nishiyama, T.2
Mishima, K.3
Inoue, H.4
Doi, T.5
Hattori, Y.6
-
154
-
-
0345734191
-
The CX3C chemokine fractalkine in allergic asthma, and rhinitis
-
Rimaniol AC, Till SJ, Garcia G, Capel F, Godot V, Balabanian K, et al. The CX3C chemokine fractalkine in allergic asthma, and rhinitis. J Allergy Clin Immunol. 2003; 112: 1139-1146.
-
(2003)
J Allergy Clin Immunol
, vol.112
, pp. 1139-1146
-
-
Rimaniol, A.C.1
Till, S.J.2
Garcia, G.3
Capel, F.4
Godot, V.5
Balabanian, K.6
-
155
-
-
0036845154
-
Migration of CX3CR1-positive T cells producing type 1 cytokines, and cytotoxic molecules into the synovium of patients with rheumatoid arthritis
-
Nanki T, Imai T, Nagasaka K, Urasaki Y, Nonomura Y, Taniguchi K, et al. Migration of CX3CR1-positive T cells producing type 1 cytokines, and cytotoxic molecules into the synovium of patients with rheumatoid arthritis. Arthritis Rheum. 2002; 46: 2878-2883.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2878-2883
-
-
Nanki, T.1
Imai, T.2
Nagasaka, K.3
Urasaki, Y.4
Nonomura, Y.5
Taniguchi, K.6
-
156
-
-
34548294270
-
P2Y2 nucleotide receptor activation up-regulates vascular cell adhesion molecule-1 [corrected] expression, and enhances lymphocyte adherence to a human submand ibular gland cell line
-
Baker OJ, Camden JM, Rome DE, Seye CI, Weisman GA. P2Y2 nucleotide receptor activation up-regulates vascular cell adhesion molecule-1 [corrected] expression, and enhances lymphocyte adherence to a human submand ibular gland cell line. Mol Immunol. 2008; 45: 65-75.
-
(2008)
Mol Immunol
, vol.45
, pp. 65-75
-
-
Baker, O.J.1
Camden, J.M.2
Rome, D.E.3
Seye, C.I.4
Weisman, G.A.5
-
157
-
-
84923309303
-
P2Y2R deficiency attenuates experimental autoimmune uveitis development
-
Relvas LJ, Makhoul M, Dewispelaere R, Caspers L, Communi D, Boeynaems JM, et al. P2Y2R deficiency attenuates experimental autoimmune uveitis development. PLoS ONE. 2015; 10: e0116518.
-
(2015)
PLoS ONE
, vol.10
, pp. e0116518
-
-
Relvas, L.J.1
Makhoul, M.2
Dewispelaere, R.3
Caspers, L.4
Communi, D.5
Boeynaems, J.M.6
-
158
-
-
78649819162
-
Alphav Integrin expression by DCs is required for Th17 cell differentiation, and development of experimental autoimmune encephalomyelitis in mice
-
Acharya M, Mukhopadhyay S, Paidassi H, Jamil T, Chow C, Kissler S, et al. alphav Integrin expression by DCs is required for Th17 cell differentiation, and development of experimental autoimmune encephalomyelitis in mice. J Clin Invest. 2010; 120: 4445-4452.
-
(2010)
J Clin Invest
, vol.120
, pp. 4445-4452
-
-
Acharya, M.1
Mukhopadhyay, S.2
Paidassi, H.3
Jamil, T.4
Chow, C.5
Kissler, S.6
-
159
-
-
61549130869
-
Heat-shock proteins can promote as well as regulate autoimmunity
-
Rajaiah R, Moudgil KD. Heat-shock proteins can promote as well as regulate autoimmunity. Autoimmun Rev. 2009; 8: 388-393.
-
(2009)
Autoimmun Rev
, vol.8
, pp. 388-393
-
-
Rajaiah, R.1
Moudgil, K.D.2
-
160
-
-
0037351507
-
Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
-
Yan SS, Wu ZY, Zhang HP, Furtado G, Chen X, Yan SF, et al. Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system. Nat Med. 2003; 9: 287-293.
-
(2003)
Nat Med
, vol.9
, pp. 287-293
-
-
Yan, S.S.1
Wu, Z.Y.2
Zhang, H.P.3
Furtado, G.4
Chen, X.5
Yan, S.F.6
-
161
-
-
0033603241
-
RAGE mediates a novel proinflammatory axis: A central cell surface receptor for S100/calgranulin polypeptides
-
Hofmann MA, Drury S, Fu C, Qu W, Taguchi A, Lu Y, et al. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell. 1999; 97: 889-901.
-
(1999)
Cell
, vol.97
, pp. 889-901
-
-
Hofmann, M.A.1
Drury, S.2
Fu, C.3
Qu, W.4
Taguchi, A.5
Lu, Y.6
-
162
-
-
0035126319
-
Deficiency or inhibition of Gas6 causes platelet dysfunction, and protects mice against thrombosis
-
Angelillo-Scherrer A, de Frutos P, Aparicio C, Melis E, Savi P, Lupu F, et al. Deficiency or inhibition of Gas6 causes platelet dysfunction, and protects mice against thrombosis. Nat Med. 2001; 7: 215-221.
-
(2001)
Nat Med
, vol.7
, pp. 215-221
-
-
Angelillo-Scherrer, A.1
De Frutos, P.2
Aparicio, C.3
Melis, E.4
Savi, P.5
Lupu, F.6
-
163
-
-
0036076461
-
Essential role of Gas6 for glomerular injury in nephrotoxic nephritis
-
Yanagita M, Ishimoto Y, Arai H, Nagai K, Ito T, Nakano T, et al. Essential role of Gas6 for glomerular injury in nephrotoxic nephritis. J Clin Invest. 2002; 110: 239-246.
-
(2002)
J Clin Invest
, vol.110
, pp. 239-246
-
-
Yanagita, M.1
Ishimoto, Y.2
Arai, H.3
Nagai, K.4
Ito, T.5
Nakano, T.6
-
164
-
-
84876452991
-
Serum growth arrest-specific protein 6 levels are a reliable biomarker of disease activity in systemic lupus erythematosus
-
Kim HA, Nam JY, Jeon JY, An JM, Jung JY, Bae CB, et al. Serum growth arrest-specific protein 6 levels are a reliable biomarker of disease activity in systemic lupus erythematosus. J Clin Immunol. 2013; 33: 143-150.
-
(2013)
J Clin Immunol
, vol.33
, pp. 143-150
-
-
Kim, H.A.1
Nam, J.Y.2
Jeon, J.Y.3
An, J.M.4
Jung, J.Y.5
Bae, C.B.6
-
165
-
-
84872727437
-
Chronic granulomatous disease
-
viii
-
Holland SM. Chronic granulomatous disease. Hematol Oncol Clin North Am. 2013; 27: 89-99, viii
-
(2013)
Hematol Oncol Clin North Am
, vol.27
, pp. 89-99
-
-
Holland, S.M.1
-
166
-
-
0034709603
-
Activation of NADPH oxidase in Alzheimers disease brains
-
Shimohama S, Tanino H, Kawakami N, Okamura N, Kodama H, Yamaguchi T, et al. Activation of NADPH oxidase in Alzheimers disease brains. Biochem Biophys Res Commun. 2000; 273: 5-9.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 5-9
-
-
Shimohama, S.1
Tanino, H.2
Kawakami, N.3
Okamura, N.4
Kodama, H.5
Yamaguchi, T.6
-
167
-
-
84919681188
-
The role of the NADPH oxidase NOX2 in prion pathogenesis
-
Sorce S, Nuvolone M, Keller A, Falsig J, Varol A, Schwarz P, et al. The role of the NADPH oxidase NOX2 in prion pathogenesis. PLoS Pathog. 2014; 10: e1004531.
-
(2014)
PLoS Pathog
, vol.10
, pp. e1004531
-
-
Sorce, S.1
Nuvolone, M.2
Keller, A.3
Falsig, J.4
Varol, A.5
Schwarz, P.6
-
168
-
-
84892436917
-
The Salih ataxia mutation impairs Rubicon endosomal localization
-
Assoum M, Salih MA, Drouot N, Hnia K, Martelli A, Koenig M. The Salih ataxia mutation impairs Rubicon endosomal localization. Cerebellum. 2013; 12: 835-840.
-
(2013)
Cerebellum
, vol.12
, pp. 835-840
-
-
Assoum, M.1
Salih, M.A.2
Drouot, N.3
Hnia, K.4
Martelli, A.5
Koenig, M.6
-
169
-
-
0344142468
-
Cloning, and genomic organization of beclin 1, a cand idate tumor suppressor gene on chromosome 17q21
-
Aita VM, Liang XH, Murty VV, Pincus DL, Yu W, Cayanis E, et al. Cloning, and genomic organization of beclin 1, a cand idate tumor suppressor gene on chromosome 17q21. Genomics. 1999; 59: 59-65.
-
(1999)
Genomics
, vol.59
, pp. 59-65
-
-
Aita, V.M.1
Liang, X.H.2
Murty, V.V.3
Pincus, D.L.4
Yu, W.5
Cayanis, E.6
-
170
-
-
0000906170
-
Induction of autophagy, and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, et al. Induction of autophagy, and inhibition of tumorigenesis by beclin 1. Nature. 1999; 402: 672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
-
171
-
-
84855196235
-
Decreased expression of Beclin-1, and LC3 in human lung cancer
-
Jiang ZF, Shao LJ, Wang WM, Yan XB, Liu RY. Decreased expression of Beclin-1, and LC3 in human lung cancer. Mol Biol Rep. 2012; 39: 259-267.
-
(2012)
Mol Biol Rep
, vol.39
, pp. 259-267
-
-
Jiang, Z.F.1
Shao, L.J.2
Wang, W.M.3
Yan, X.B.4
Liu, R.Y.5
-
172
-
-
77956396747
-
Defective CFTR induces aggresome formation, and lung inflammation in cystic fibrosis through ROSmediated autophagy inhibition
-
Luciani A, Villella VR, Esposito S, Brunetti-Pierri N, Medina D, Settembre C, et al. Defective CFTR induces aggresome formation, and lung inflammation in cystic fibrosis through ROSmediated autophagy inhibition. Nat Cell Biol. 2010; 12: 863-875.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 863-875
-
-
Luciani, A.1
Villella, V.R.2
Esposito, S.3
Brunetti-Pierri, N.4
Medina, D.5
Settembre, C.6
-
173
-
-
45749114895
-
The autophagyrelated protein beclin 1 shows reduced expression in early Alzheimer disease, and regulates amyloid beta accumulation in mice
-
Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, et al. The autophagyrelated protein beclin 1 shows reduced expression in early Alzheimer disease, and regulates amyloid beta accumulation in mice. J Clin Invest. 2008; 118: 2190-2199.
-
(2008)
J Clin Invest
, vol.118
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
-
175
-
-
42749084544
-
Investigation of variants in the promoter region of PIK3C3 in schizophrenia
-
Tang R, Zhao X, Fang C, Tang W, Huang K, Wang L, et al. Investigation of variants in the promoter region of PIK3C3 in schizophrenia. Neurosci Lett. 2008; 437: 42-44.
-
(2008)
Neurosci Lett
, vol.437
, pp. 42-44
-
-
Tang, R.1
Zhao, X.2
Fang, C.3
Tang, W.4
Huang, K.5
Wang, L.6
-
176
-
-
45049083880
-
Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
-
Kim MS, Jeong EG, Ahn CH, Kim SS, Lee SH, Yoo NJ. Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability. Hum Pathol. 2008; 39: 1059-1063.
-
(2008)
Hum Pathol
, vol.39
, pp. 1059-1063
-
-
Kim, M.S.1
Jeong, E.G.2
Ahn, C.H.3
Kim, S.S.4
Lee, S.H.5
Yoo, N.J.6
-
177
-
-
77954856461
-
Association of UVRAG polymorphisms with susceptibility to non-segmental vitiligo in a Korean sample
-
Jeong TJ, Shin MK, Uhm YK, Kim HJ, Chung JH, Lee MH. Association of UVRAG polymorphisms with susceptibility to non-segmental vitiligo in a Korean sample. Exp Dermatol. 2010; 19: e323-e325.
-
(2010)
Exp Dermatol
, vol.19
, pp. e323-e325
-
-
Jeong, T.J.1
Shin, M.K.2
Uhm, Y.K.3
Kim, H.J.4
Chung, J.H.5
Lee, M.H.6
-
178
-
-
33745751085
-
Autophagic, and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, et al. Autophagic, and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol. 2006; 8: 688-699.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Dotan, I.4
Canaani, D.5
Oh, B.H.6
-
179
-
-
84859951546
-
Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma
-
Martin LJ, Gupta J, Jyothula SS, Butsch Kovacic M, Biagini Myers JM, Patterson TL, et al. Functional variant in the autophagy-related 5 gene promotor is associated with childhood asthma. PLoS ONE. 2012; 7: e33454.
-
(2012)
PLoS ONE
, vol.7
, pp. e33454
-
-
Martin, L.J.1
Gupta, J.2
Jyothula, S.S.3
Butsch Kovacic, M.4
Biagini Myers, J.M.5
Patterson, T.L.6
-
180
-
-
79957629559
-
Genetic association of PRDM1-ATG5 intergenic region, and autophagy with systemic lupus erythematosus in a Chinese population
-
Zhou XJ, Lu XL, Lv JC, Yang HZ, Qin LX, Zhao MH, et al. Genetic association of PRDM1-ATG5 intergenic region, and autophagy with systemic lupus erythematosus in a Chinese population. Ann Rheum Dis. 2011; 70: 1330-1337.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1330-1337
-
-
Zhou, X.J.1
Lu, X.L.2
Lv, J.C.3
Yang, H.Z.4
Qin, L.X.5
Zhao, M.H.6
-
181
-
-
84855516226
-
Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells
-
Ireland JM, Unanue ER. Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells. J Exp Med. 2011; 208: 2625-2632.
-
(2011)
J Exp Med
, vol.208
, pp. 2625-2632
-
-
Ireland, J.M.1
Unanue, E.R.2
-
182
-
-
79957917512
-
A small-molecule enhancer of autophagy decreases levels of Abeta, and APP-CTF via Atg5-dependent autophagy pathway
-
Tian Y, Bustos V, Flajolet M, Greengard P A small-molecule enhancer of autophagy decreases levels of Abeta, and APP-CTF via Atg5-dependent autophagy pathway. FASEB J. 2011; 25: 1934-1942.
-
(2011)
FASEB J.
, vol.25
, pp. 1934-1942
-
-
Tian, Y.1
Bustos, V.2
Flajolet, M.3
Greengard, P.4
-
183
-
-
70350629871
-
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
-
Han JW, Zheng HF, Cui Y, Sun LD, Ye DQ, Hu Z, et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet. 2009; 41: 1234-1237.
-
(2009)
Nat Genet
, vol.41
, pp. 1234-1237
-
-
Han, J.W.1
Zheng, H.F.2
Cui, Y.3
Sun, L.D.4
Ye, D.Q.5
Hu, Z.6
-
184
-
-
84862791715
-
Macrophage autophagy plays a protective role in advanced atherosclerosis
-
Liao X, Sluimer JC, Wang Y, Subramanian M, Brown K, Pattison JS, et al. Macrophage autophagy plays a protective role in advanced atherosclerosis. Cell Metab. 2012; 15: 545-553.
-
(2012)
Cell Metab
, vol.15
, pp. 545-553
-
-
Liao, X.1
Sluimer, J.C.2
Wang, Y.3
Subramanian, M.4
Brown, K.5
Pattison, J.S.6
-
185
-
-
56249135538
-
A key role for autophagy, and the autophagy gene Atg16l1 in mouse, and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, et al A key role for autophagy, and the autophagy gene Atg16l1 in mouse, and human intestinal Paneth cells. Nature. 2008; 456: 259-263.
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
-
186
-
-
84933074128
-
ATG16L1 expression in carotid atherosclerotic plaques is associated with plaque vulnerability
-
Magne J, Gustafsson P, Jin H, Maegdefessel L, Hultenby K, Wernerson A, et al. ATG16L1 expression in carotid atherosclerotic plaques is associated with plaque vulnerability. Arterioscler Thromb Vasc Biol. 2015; 35: 1226-1235.
-
(2015)
Arterioscler Thromb Vasc Biol
, vol.35
, pp. 1226-1235
-
-
Magne, J.1
Gustafsson, P.2
Jin, H.3
Maegdefessel, L.4
Hultenby, K.5
Wernerson, A.6
-
187
-
-
84926659754
-
Autophagy is activated in systemic lupus erythematosus, and required for plasmablast development
-
Clarke AJ, Ellinghaus U, Cortini A, Stranks A, Simon AK, Botto M, et al. Autophagy is activated in systemic lupus erythematosus, and required for plasmablast development. Ann Rheum Dis. 2015; 74: 912-920.
-
(2015)
Ann Rheum Dis
, vol.74
, pp. 912-920
-
-
Clarke, A.J.1
Ellinghaus, U.2
Cortini, A.3
Stranks, A.4
Simon, A.K.5
Botto, M.6
-
188
-
-
84907195348
-
Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis
-
Bhattacharya A, Parillon X, Zeng S, Han S, Eissa NT. Deficiency of autophagy in dendritic cells protects against experimental autoimmune encephalomyelitis. J Biol Chem. 2014; 289: 26525-26532.
-
(2014)
J Biol Chem
, vol.289
, pp. 26525-26532
-
-
Bhattacharya, A.1
Parillon, X.2
Zeng, S.3
Han, S.4
Eissa, N.T.5
-
189
-
-
70649086092
-
Genetic variants at CD28 PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
-
Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, et al. Genetic variants at CD28, PRDM1, and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet. 2009; 41: 1313-1318.
-
(2009)
Nat Genet
, vol.41
, pp. 1313-1318
-
-
Raychaudhuri, S.1
Thomson, B.P.2
Remmers, E.F.3
Eyre, S.4
Hinks, A.5
Guiducci, C.6
-
190
-
-
84890072367
-
Enhanced autophagy ameliorates cardiac proteinopathy
-
Bhuiyan MS, Pattison JS, Osinska H, James J, Gulick J, McLendon PM, et al. Enhanced autophagy ameliorates cardiac proteinopathy. J Clin Invest. 2013; 123: 5284-5297.
-
(2013)
J Clin Invest
, vol.123
, pp. 5284-5297
-
-
Bhuiyan, M.S.1
Pattison, J.S.2
Osinska, H.3
James, J.4
Gulick, J.5
McLendon, P.M.6
-
191
-
-
77954992496
-
A balancing act for autophagin
-
Till A, Subramani S A balancing act for autophagin. J Clin Invest. 2010; 120: 2273-2276.
-
(2010)
J Clin Invest
, vol.120
, pp. 2273-2276
-
-
Till, A.1
Subramani, S.2
-
192
-
-
84900404767
-
LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains
-
Satoh J, Motohashi N, Kino Y, Ishida T, Yagishita S, Jinnai K, et al. LC3, an autophagosome marker, is expressed on oligodendrocytes in Nasu-Hakola disease brains. Orphanet J Rare Dis. 2014; 9: 68.
-
(2014)
Orphanet J Rare Dis
, vol.9
, pp. 68
-
-
Satoh, J.1
Motohashi, N.2
Kino, Y.3
Ishida, T.4
Yagishita, S.5
Jinnai, K.6
-
193
-
-
67349150186
-
Autophagy in human type 2 diabetes pancreatic beta cells
-
Masini M, Bugliani M, Lupi R, del Guerra S, Boggi U, Filipponi F, et al. Autophagy in human type 2 diabetes pancreatic beta cells. Diabetologia. 2009; 52: 1083-1086.
-
(2009)
Diabetologia
, vol.52
, pp. 1083-1086
-
-
Masini, M.1
Bugliani, M.2
Lupi, R.3
Del Guerra, S.4
Boggi, U.5
Filipponi, F.6
-
194
-
-
79955790354
-
Genetic variation in the autophagy gene ULK1, and risk of Crohns disease
-
Henckaerts L, Cleynen I, Brinar M, John JM, Van Steen K, Rutgeerts P, et al. Genetic variation in the autophagy gene ULK1, and risk of Crohns disease. Inflamm Bowel Dis. 2011; 17: 1392-1397.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1392-1397
-
-
Henckaerts, L.1
Cleynen, I.2
Brinar, M.3
John, J.M.4
Van Steen, K.5
Rutgeerts, P.6
-
195
-
-
65549159637
-
Inactivation of FIP200 leads to inflammatory skin disorder, but not tumorigenesis, in conditional knock-out mouse models
-
Wei H, Gan B, Wu X, Guan JL. Inactivation of FIP200 leads to inflammatory skin disorder, but not tumorigenesis, in conditional knock-out mouse models. J Biol Chem. 2009; 284: 6004-6013.
-
(2009)
J Biol Chem
, vol.284
, pp. 6004-6013
-
-
Wei, H.1
Gan, B.2
Wu, X.3
Guan, J.L.4
-
196
-
-
77951665859
-
Cargo recognition failure is responsible for inefficient autophagy in Huntingtons disease
-
Martinez-Vicente M, Talloczy Z, Wong E, Tang G, Koga H, Kaushik S, et al. Cargo recognition failure is responsible for inefficient autophagy in Huntingtons disease. Nat Neurosci. 2010; 13: 567-576.
-
(2010)
Nat Neurosci
, vol.13
, pp. 567-576
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Wong, E.3
Tang, G.4
Koga, H.5
Kaushik, S.6
-
197
-
-
84871952426
-
Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy
-
Cullup T, Kho AL, Dionisi-Vici C, Brandmeier B, Smith F, Urry Z, et al. Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy. Nat Genet. 2013; 45: 83-87.
-
(2013)
Nat Genet
, vol.45
, pp. 83-87
-
-
Cullup, T.1
Kho, A.L.2
Dionisi-Vici, C.3
Brandmeier, B.4
Smith, F.5
Urry, Z.6
-
198
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM, and multiple other replicating loci contribute to Crohns disease susceptibility
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, et al. Sequence variants in the autophagy gene IRGM, and multiple other replicating loci contribute to Crohns disease susceptibility. Nat Genet. 2007; 39: 830-832.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
-
199
-
-
77950296637
-
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22, and 22q13 (IL17REL
-
Franke A, Balschun T, Sina C, Ellinghaus D, Hasler R, Mayr G, et al. Genome-wide association study for ulcerative colitis identifies risk loci at 7q22, and 22q13 (IL17REL). Nat Genet. 2010; 42: 292-294.
-
(2010)
Nat Genet
, vol.42
, pp. 292-294
-
-
Franke, A.1
Balschun, T.2
Sina, C.3
Ellinghaus, D.4
Hasler, R.5
Mayr, G.6
-
200
-
-
84875757691
-
De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood
-
449e1
-
Saitsu H, Nishimura T, Muramatsu K, Kodera H, Kumada S, Sugai K, et al. De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood. Nat Genet. 2013; 45: 445-449, 449e1.
-
(2013)
Nat Genet
, vol.45
, pp. 445-449
-
-
Saitsu, H.1
Nishimura, T.2
Muramatsu, K.3
Kodera, H.4
Kumada, S.5
Sugai, K.6
-
201
-
-
2442668926
-
Hereditary early-onset Parkinsons disease caused bymutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, et al. Hereditary early-onset Parkinsons disease caused bymutations in PINK1. Science. 2004; 304: 1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
-
202
-
-
75949130828
-
PINK1/Parkinmediated mitophagy is dependent on VDAC1, and p62/SQSTM1
-
Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, et al. PINK1/Parkinmediated mitophagy is dependent on VDAC1, and p62/SQSTM1. Nat Cell Biol. 2010; 12: 119-131.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
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