-
1
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
Boya, P. et al. Inhibition of macroautophagy triggers apoptosis. Mol. Cell Biol. 25, 1025-1040 (2005).
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
-
2
-
-
14044277429
-
The molecular machinery of autophagy: Unanswered questions
-
Klionsky, D. J. The molecular machinery of autophagy: Unanswered questions. J. Cell Sci. 118, 7-18 (2005).
-
(2005)
J. Cell Sci.
, vol.118
, pp. 7-18
-
-
Klionsky, D.J.1
-
3
-
-
12944308330
-
Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
-
Levine, B. Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense. Cell 120, 159-162 (2005).
-
(2005)
Cell
, vol.120
, pp. 159-162
-
-
Levine, B.1
-
4
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine, B. & Klionsky, D. J. Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev. Cell 6, 463-477 (2004).
-
(2004)
Dev. Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
5
-
-
20344406240
-
Autophagy in metazoans: Cell survival in the land of plenty
-
Lum, J. J., DeBerardinis, R. J. & Thompson, C. B. Autophagy in metazoans: Cell survival in the land of plenty. Nature Rev. Mol. Cell Biol. 6, 439-448 (2005).
-
(2005)
Nature Rev. Mol. Cell Biol.
, vol.6
, pp. 439-448
-
-
Lum, J.J.1
DeBerardinis, R.J.2
Thompson, C.B.3
-
6
-
-
0035809160
-
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
-
Kihara, A., Noda, T., Ishihara, N. & Ohsumi, Y. Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J. Cell Biol. 152, 519-530 (2001).
-
(2001)
J. Cell Biol.
, vol.152
, pp. 519-530
-
-
Kihara, A.1
Noda, T.2
Ishihara, N.3
Ohsumi, Y.4
-
7
-
-
0035503594
-
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
-
Suzuki, K. et al. The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J. 20, 5971-5981 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 5971-5981
-
-
Suzuki, K.1
-
8
-
-
39049194057
-
The evolutionarily conserved domain of beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
-
Furuya N., Yu J., Byfield M., Pattingre S & B., L. The evolutionarily conserved domain of beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 1, 46-52 (2005).
-
(2005)
Autophagy
, vol.1
, pp. 46-52
-
-
Furuya, N.1
Yu, J.2
Byfield, M.3
Pattingre, S.B.L.4
-
9
-
-
0344142468
-
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
-
Aita, V. M. et al. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 59, 59-65 (1999).
-
(1999)
Genomics
, vol.59
, pp. 59-65
-
-
Aita, V.M.1
-
10
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang, X. H. et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402, 672-676 (1999).
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
-
11
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu, X. et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J. Clin. Invest. 112, 1809-1820 (2003).
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
-
12
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue, Z., Jin, S., Yang, C., Levine, A. J. & Heintz, N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc. Natl Acad. Sci. USA 100, 15077-15082 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
13
-
-
2442482810
-
Autophagy as a cell death and tumor suppressor mechanism
-
Gozuacik, D. & Kimchi, A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23, 2891-2906 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 2891-2906
-
-
Gozuacik, D.1
Kimchi, A.2
-
14
-
-
0030883558
-
Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells
-
Jia, L. et al. Inhibition of autophagy abrogates tumour necrosis factor alpha induced apoptosis in human T-lymphoblastic leukaemic cells. Br. J. Haematol. 98, 673-685 (1997).
-
(1997)
Br. J. Haematol.
, vol.98
, pp. 673-685
-
-
Jia, L.1
-
15
-
-
1542513774
-
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro
-
Mills, K. R., Reginato, M., Debnath, J., Queenan, B. & Brugge, J. S. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro. Proc. Natl Acad. Sci. USA 101, 3438-3443 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 3438-3443
-
-
Mills, K.R.1
Reginato, M.2
Debnath, J.3
Queenan, B.4
Brugge, J.S.5
-
16
-
-
14844310233
-
Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells
-
Thorburn, J. et al. Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells. Mol. Biol. Cell 16, 1189-1199 (2005).
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 1189-1199
-
-
Thorburn, J.1
-
17
-
-
0035929650
-
The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
-
Arico, S. et al. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J. Biol. Chem. 276, 35243-35246 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35243-35246
-
-
Arico, S.1
-
18
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre, S. et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122, 927-939 (2005).
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
-
19
-
-
10344262564
-
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
-
Shimizu, S. et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nature Cell Biol. 6, 1221-1228 (2004).
-
(2004)
Nature Cell Biol.
, vol.6
, pp. 1221-1228
-
-
Shimizu, S.1
-
20
-
-
0030738667
-
Complete sequence and genomic analysis of murine gammaherpesvirus 68
-
Virgin, H. W. t. et al. Complete sequence and genomic analysis of murine gammaherpesvirus 68. J. Virol. 71, 5894-5904 (1997).
-
(1997)
J. Virol.
, vol.71
, pp. 5894-5904
-
-
Virgin, H.W.T.1
-
21
-
-
1442301767
-
Viral Bcl-2 homologs and their role in virus replication and associated diseases
-
Polster, B. M., Pevsner, J. & Hardwick, J. M. Viral Bcl-2 homologs and their role in virus replication and associated diseases. Biochim. Biophys. Acta. 1644, 211-227 (2004).
-
(2004)
Biochim. Biophys. Acta.
, vol.1644
, pp. 211-227
-
-
Polster, B.M.1
Pevsner, J.2
Hardwick, J.M.3
-
22
-
-
0034517673
-
Murine gammaherpesvirus M11 gene product inhibits apoptosis and is expressed during virus persistence
-
Roy, D. J., Ebrahimi, B. C., Dutia, B. M., Nash, A. A. & Stewart, J. P. Murine gammaherpesvirus M11 gene product inhibits apoptosis and is expressed during virus persistence. Arch. Virol. 145, 2411-2420 (2000).
-
(2000)
Arch. Virol.
, vol.145
, pp. 2411-2420
-
-
Roy, D.J.1
Ebrahimi, B.C.2
Dutia, B.M.3
Nash, A.A.4
Stewart, J.P.5
-
23
-
-
0032861298
-
The murine gammaherpesvirus-68 M11 protein inhibits Fas- and TNF-induced apoptosis
-
Wang, G. H., Garvey, T. L. & Cohen, J. I. The murine gammaherpesvirus-68 M11 protein inhibits Fas- and TNF-induced apoptosis. J. Gen. Virol. 80, 2737-2740 (1999).
-
(1999)
J. Gen. Virol.
, vol.80
, pp. 2737-2740
-
-
Wang, G.H.1
Garvey, T.L.2
Cohen, J.I.3
-
24
-
-
11444254723
-
Murine gammaherpesvirus 68 bcl-2 homologue contributes to latency establishment in vivo
-
de Lima, B. D., May, J. S., Marques, S., Simas, J. P. & Stevenson, P. G. Murine gammaherpesvirus 68 bcl-2 homologue contributes to latency establishment in vivo. J. Gen. Virol. 86, 31-40 (2005).
-
(2005)
J. Gen. Virol.
, vol.86
, pp. 31-40
-
-
de Lima, B.D.1
May, J.S.2
Marques, S.3
Simas, J.P.4
Stevenson, P.G.5
-
25
-
-
0036534608
-
Identification of the in vivo role of a viral bcl-2
-
Gangappa, S., van Dyk, L. F., Jewett, T. J., Speck, S. H. & Virgin, H. W. IV. Identification of the in vivo role of a viral bcl-2. J. Exp. Med. 195, 931-940 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 931-940
-
-
Gangappa, S.1
van Dyk, L.F.2
Jewett, T.J.3
Speck, S.H.4
Virgin IV, H.W.5
-
26
-
-
2642642963
-
Detailed map of a region commonly amplified at 11q13→q14 in human breast carcinoma
-
Bekri, S. et al. Detailed map of a region commonly amplified at 11q13→q14 in human breast carcinoma. Cytogenet. Cell. Genet. 79, 125-131 (1997).
-
(1997)
Cytogenet. Cell. Genet.
, vol.79
, pp. 125-131
-
-
Bekri, S.1
-
27
-
-
0031149239
-
Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus
-
Perelman, B. et al. Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus. Genomics 41, 397-405 (1997).
-
(1997)
Genomics
, vol.41
, pp. 397-405
-
-
Perelman, B.1
-
28
-
-
0042836544
-
Ascending colon cancer with hepatic metastasis and cholecystolithiasis in a patient with situs inversus totalis without any expression of UVRAG mRNA: Report of a case
-
Goi, T. et al. Ascending colon cancer with hepatic metastasis and cholecystolithiasis in a patient with situs inversus totalis without any expression of UVRAG mRNA: Report of a case. Surg. Today 33, 702-706 (2003).
-
(2003)
Surg. Today
, vol.33
, pp. 702-706
-
-
Goi, T.1
-
29
-
-
1242296021
-
Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability
-
Ionov, Y., Nowak, N., Perucho, M., Markowitz, S. & Cowell, J. K. Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability. Oncogene 23, 639-645 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 639-645
-
-
Ionov, Y.1
Nowak, N.2
Perucho, M.3
Markowitz, S.4
Cowell, J.K.5
-
30
-
-
0001488499
-
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
-
Liang, X. H. et al. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. J. Virol. 72, 8586-8596 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 8586-8596
-
-
Liang, X.H.1
-
31
-
-
33745756937
-
A surface groove essential for viral bcl-2 function during chronic infection in vivo
-
Loh, J. et al. A surface groove essential for viral bcl-2 function during chronic infection in vivo. PLoS Pathog. 1, e10 (2005).
-
(2005)
PLoS Pathog.
, vol.1
-
-
Loh, J.1
-
32
-
-
4344624322
-
LC3 conjugation system in mammalian autophagy
-
Tanida, I., Ueno, T. & Kominami, E. LC3 conjugation system in mammalian autophagy. Int. J. Biochem. Cell. Biol. 36, 2503-2518 (2004).
-
(2004)
Int. J. Biochem. Cell. Biol.
, vol.36
, pp. 2503-2518
-
-
Tanida, I.1
Ueno, T.2
Kominami, E.3
-
33
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima, N., Yamamoto, A., Matsui, M., Yoshimori, T. & Ohsumi, Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol. Biol. Cell 15, 1101-1111 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
34
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya, Y. et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 19, 5720-5728 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
-
35
-
-
0035494493
-
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation
-
Vieira, O. V. et al. Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation. J. Cell Biol. 155, 19-25 (2001).
-
(2001)
J. Cell Biol.
, vol.155
, pp. 19-25
-
-
Vieira, O.V.1
-
36
-
-
25144506835
-
Autophagy in cell death: An innocent convict?
-
Levine, B. & Yuan, J. Autophagy in cell death: An innocent convict? J. Clin. Invest. 115, 2679-2688 (2005).
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2679-2688
-
-
Levine, B.1
Yuan, J.2
-
37
-
-
0034030932
-
Identification of a gene disrupted by inv(11)(q13.5;q25) in a patient with left-right axis malformation
-
Iida, A. et al. Identification of a gene disrupted by inv(11)(q13.5;q25) in a patient with left-right axis malformation. Hum. Genet. 106, 277-287 (2000).
-
(2000)
Hum. Genet.
, vol.106
, pp. 277-287
-
-
Iida, A.1
-
38
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum, J. J. et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120, 237-248 (2005).
-
(2005)
Cell
, vol.120
, pp. 237-248
-
-
Lum, J.J.1
-
39
-
-
26444575415
-
Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase
-
Nobukuni, T. et al. Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. Proc. Natl Acad. Sci. USA 102, 14238-14243 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 14238-14243
-
-
Nobukuni, T.1
|