Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis

Nature Medicine

Volumn 7, Issue 2, 2001, Pages 215-221

  Angelillo Scherrer, Anne ^a   De Frutos, Pablo Garcia ^b   Aparicio, Cristina ^b   Melis, Els ^a   Savi, Pierre ^c   Lupu, Florea ^d   Arnout, Jef ^a   Dewerchin, Mieke ^a   Hoylaerts, Marc F ^a   Herbert, Jean Marc ^c   Collen, Désiré ^a   Dahlbäck, Björn ^b   Carmeliet, Peter ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b LUND UNIVERSITY   (Sweden)

^c SANOFI   (France)

^d THROMBOSIS RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; CALCIMYCIN; COLLAGEN; GENE PRODUCT; GROWTH ARREST SPECIFIC PROTEIN 6; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN S; RECOMBINANT PROTEIN GAS6; THROMBIN; THROMBOXANE A2 DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; CONTROLLED STUDY; GENE AMPLIFICATION; GROWTH INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; THROMBOCYTE DYSFUNCTION; THROMBOSIS PREVENTION;

ANIMALS; BLOOD PLATELETS; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HEMOSTASIS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, KNOCKOUT; PHENOTYPE; PLATELET AGGREGATION; PROTEINS; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; THROMBOSIS;

ANIMALIA;

EID: 0035126319     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/84667     Document Type: Article

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