A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis

Arthritis Research and Therapy

Volumn 12, Issue 1, 2010, Pages

  Abreu, Joana R F ^a   Dontje, Wendy ^a   Krausz, Sarah ^a   de Launay, Daphne ^a   van Hennik, Paula B ^a   van Stalborch, Anne Marieke ^a   ten Klooster, Jean Paul ^a   Sanders, Marjolein E ^a   Reedquist, Kris A ^a   Vervoordeldonk, Margriet J ^a,b   Hordijk, Peter L ^a   Tak, Paul P ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b Arthrogen BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; RAC1 PROTEIN; T LYMPHOCYTE RECEPTOR; ANTIRHEUMATIC AGENT; AUTOANTIBODY; CYTOKINE; NEUROPEPTIDE; PEPTIDE; RAC PROTEIN; RAC1 PROTEIN, MOUSE;

ACTIN POLYMERIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CELL MEMBRANE PERMEABILITY; CELL SELECTION; DISEASE COURSE; JOINT DESTRUCTION; MALE; MOUSE; NONHUMAN; PAW EDEMA; PHENOTYPE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; ANIMAL; ARTHRITIS; BIOSYNTHESIS; DBA MOUSE; DRUG ANTAGONISM; DRUG EFFECT; EDEMA; ENZYME LINKED IMMUNOSORBENT ASSAY; HINDLIMB; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY; T LYMPHOCYTE;

ANIMALS; ANTIBODY FORMATION; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; B-LYMPHOCYTES; COLLAGEN TYPE II; CYTOKINES; EDEMA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HINDLIMB; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED DBA; NEUROPEPTIDES; PEPTIDES; RAC GTP-BINDING PROTEINS; T-LYMPHOCYTES;

EID: 77955490256     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2900     Document Type: Article

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