Adaptor protein GULP is involved in stabilin-1-mediated phagocytosis

Biochemical and Biophysical Research Communications

Volumn 398, Issue 3, 2010, Pages 467-472

  Park, Seung Yoon ^b   Kim, Sang Yeob ^a   Kang, Kae Bok ^a   Kim, In San ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Dongguk University College of Medicine   (South Korea)

Author keywords

Aged RBC; GULP; Phagocytosis; Phosphatidylserine; Stabilin 1

Indexed keywords

ADAPTOR PROTEIN; PROTEIN GULP; RECEPTOR PROTEIN; STABILIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL ADHESION MOLECULES, NEURONAL; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MOLECULAR SEQUENCE DATA; PHAGOCYTOSIS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, LYMPHOCYTE HOMING;

EID: 77955282364     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.06.101     Document Type: Article

References (29)

1. Goerdt S., Walsh L.J., Murphy G.F., Pober J.S. Identification of a novel high molecular weight protein preferentially expressed by sinusoidal endothelial cells in normal human tissues. J. Cell Biol. 1991, 113:1425-1437.
2. Tamura Y., Adachi H., Osuga J., Ohashi K., Yahagi N., Sekiya M., Okazaki H., Tomita S., Iizuka Y., Shimano H., Nagai R., Kimura S., Tsujimoto M., Ishibashi S. FEEL-1 and FEEL-2 are endocytic receptors for advanced glycation end products. J. Biol. Chem. 2003, 278:12613-12617.
3. Adachi H., Tsujimoto M. FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities. J. Biol. Chem. 2002, 277:34264-34270.
4. Kzhyshkowska J., Gratchev A., Brundiers H., Mamidi S., Krusell L., Goerdt S. Phosphatidylinositide 3-kinase activity is required for stabilin-1-mediated endosomal transport of acLDL. Immunobiology 2005, 210:161-173.
5. Kzhyshkowska J., Workman G., Cardo-Vila M., Arap W., Pasqualini R., Gratchev A., Krusell L., Goerdt S., Sage E.H. Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC. J. Immunol. 2006, 176:5825-5832.
6. Kzhyshkowska J., Mamidi S., Gratchev A., Kremmer E., Schmuttermaier C., Krusell L., Haus G., Utikal J., Schledzewski K., Scholtze J., Goerdt S. Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway. Blood 2006, 107:3221-3228.
7. Kzhyshkowska J., Gratchev A., Schmuttermaier C., Brundiers H., Krusell L., Mamidi S., Zhang J., Workman G., Sage E.H., Anderle C., Sedlmayr P., Goerdt S. Alternatively activated macrophages regulate extracellular levels of the hormone placental lactogen via receptor-mediated uptake and transcytosis. J. Immunol. 2008, 180:3028-3037.
8. Park S.Y., Jung M.Y., Lee S.J., Kang K.B., Gratchev A., Riabov V., Kzhyshkowska J., Kim I.S. Stabilin-1 mediates phosphatidylserine-dependent clearance of cell corpses in alternatively activated macrophages. J. Cell Sci. 2009, 122:3365-3373.
9. Liu Q.A., Hengartner M.O. Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans. Cell 1998, 93:961-972.
10. Liu Q.A., Hengartner M.O. Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6. Curr. Biol. 1999, 9:1347-1350.
11. Su H.P., Nakada-Tsukui K., Tosello-Trampont A.C., Li Y., Bu G., Henson P.M., Ravichandran K.S. Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP). J. Biol. Chem. 2002, 277:11772-11779.
12. Suzuki E., Nakayama M. MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation. Exp. Cell Res. 2007.
13. Park S.Y., Kang K.B., Thapa N., Kim S.Y., Lee S.J., Kim I.S. Requirement of adaptor protein GULP during stabilin-2-mediated cell corpse engulfment. J. Biol. Chem. 2008, 283:10593-10600.
14. Kim J.E., Kim S.J., Lee B.H., Park R.W., Kim K.S., Kim I.S. Identification of motifs for cell adhesion within the repeated domains of transforming growth factor-beta-induced gene, betaig-h3. J. Biol. Chem. 2000, 275:30907-30915.
15. Park S.Y., Jung M.Y., Kim H.J., Lee S.J., Kim S.Y., Lee B.H., Kwon T.H., Park R.W., Kim I.S. Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor. Cell Death Differ. 2008, 15:192-201.
16. Park S.Y., Kim S.Y., Jung M.Y., Bae D.J., Kim I.S. Epidermal growth factor-like domain repeat of stabilin-2 recognizes phosphatidylserine during cell corpse clearance. Mol. Cell Biol. 2008, 28:5288-5298.
17. Hamon Y., Trompier D., Ma Z., Venegas V., Pophillat M., Mignotte V., Zhou Z., Chimini G. Cooperation between engulfment receptors: the case of ABCA1 and MEGF10. PLoS ONE 2006, 1:e120.
18. Gigli I., Nelson R.A. Complement dependent immune phagocytosis. I. Requirements for C'1, C'4, C'2, C'3. Exp. Cell Res. 1968, 51:45-67.
19. Gumienny T.L., Brugnera E., Tosello-Trampont A.C., Kinchen J.M., Haney L.B., Nishiwaki K., Walk S.F., Nemergut M.E., Macara I.G., Francis R., Schedl T., Qin Y., Van Aelst L., Hengartner M.O., Ravichandran K.S. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell 2001, 107:27-41.
20. Ellis R.E., Jacobson D.M., Horvitz H.R. Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics 1991, 129:79-94.
21. Park D., Tosello-Trampont A.C., Elliott M.R., Lu M., Haney L.B., Ma Z., Klibanov A.L., Mandell J.W., Ravichandran K.S. BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module. Nature 2007, 450:430-434.
22. Albert M.L., Kim J.I., Birge R.B. Alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells. Nat. Cell Biol. 2000, 2:899-905.
23. Wu Y., Singh S., Georgescu M.M., Birge R.B. A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells. J. Cell Sci. 2005, 118:539-553.
24. Zhou Z., Hartwieg E., Horvitz H.R. CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans. Cell 2001, 104:43-56.
25. Calderwood D.A., Fujioka Y., de Pereda J.M., Garcia-Alvarez B., Nakamoto T., Margolis B., McGlade C.J., Liddington R.C., Ginsberg M.H. Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling. Proc. Natl. Acad. Sci. USA 2003, 100:2272-2277.
26. Siegal G. The surprisingly flexible PTB domain. Nat. Struct. Biol. 1999, 6:7-10.
27. Kzhyshkowska J., Gratchev A., Martens J.H., Pervushina O., Mamidi S., Johansson S., Schledzewski K., Hansen B., He X., Tang J., Nakayama K., Goerdt S. Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors. J. Leukoc. Biol. 2004, 76:1151-1161.
28. Zhang J., Gratchev A., Riabov V., Mamidi S., Schmuttermaier C., Krusell L., Kremmer E., Workman G., Sage E.H., Jalkanen S., Goerdt S., Kzhyshkowska J. A novel GGA-binding site is required for intracellular sorting mediated by stabilin-1. Mol. Cell Biol. 2009, 29:6097-6105.
29. Adachi H., Tsujimoto M. Adaptor protein sorting nexin 17 interacts with the scavenger receptor FEEL-1/stabilin-1 and modulates its expression on the cell surface. Biochim. Biophys. Acta. 2010, 1803:553-563.