-
1
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene
-
Alam J., Stewart D., Touchard C., Boinapally S., Choi A.M., Cook J.L. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J. Biol. Chem. 1999, 274:26071-26078.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
Boinapally, S.4
Choi, A.M.5
Cook, J.L.6
-
2
-
-
33646831500
-
NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox
-
Anrather J., Racchumi G., Iadecola C. NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. J. Biol. Chem. 2006, 281:5657-5667.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5657-5667
-
-
Anrather, J.1
Racchumi, G.2
Iadecola, C.3
-
3
-
-
80054114689
-
Hepcidin regulation by innate immune and infectious stimuli
-
Armitage A.E., Eddowes L.A., Gileadi U., Cole S., Spottiswoode N., Selvakumar T.A., Ho L.P., Townsend A.R., Drakesmith H. Hepcidin regulation by innate immune and infectious stimuli. Blood 2011, 118:4129-4139.
-
(2011)
Blood
, vol.118
, pp. 4129-4139
-
-
Armitage, A.E.1
Eddowes, L.A.2
Gileadi, U.3
Cole, S.4
Spottiswoode, N.5
Selvakumar, T.A.6
Ho, L.P.7
Townsend, A.R.8
Drakesmith, H.9
-
4
-
-
38949110010
-
Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages
-
Ashino T., Yamanaka R., Yamamoto M., Shimokawa H., Sekikawa K., Iwakura Y., Shioda S., Numazawa S., Yoshida T. Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages. Mol. Immunol. 2008, 45:2106-2115.
-
(2008)
Mol. Immunol.
, vol.45
, pp. 2106-2115
-
-
Ashino, T.1
Yamanaka, R.2
Yamamoto, M.3
Shimokawa, H.4
Sekikawa, K.5
Iwakura, Y.6
Shioda, S.7
Numazawa, S.8
Yoshida, T.9
-
5
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
-
Beckman J.S., Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am. J. Physiol. 1996, 271:C1424-C1437.
-
(1996)
Am. J. Physiol.
, vol.271
, pp. C1424-C1437
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
6
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
-
Bedard K., Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 2007, 87:245-313.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
7
-
-
33644649611
-
Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice
-
Belcher J.D., Mahaseth H., Welch T.E., Otterbein L.E., Hebbel R.P., Vercellotti G.M. Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice. J. Clin. Invest. 2006, 116:808-816.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 808-816
-
-
Belcher, J.D.1
Mahaseth, H.2
Welch, T.E.3
Otterbein, L.E.4
Hebbel, R.P.5
Vercellotti, G.M.6
-
8
-
-
32444442757
-
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury
-
Berger T., Togawa A., Duncan G.S., Elia A.J., You-Ten A., Wakeham A., Fong H.E., Cheung C.C., Mak T.W. Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proc. Natl. Acad. Sci. USA 2006, 103:1834-1839.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 1834-1839
-
-
Berger, T.1
Togawa, A.2
Duncan, G.S.3
Elia, A.J.4
You-Ten, A.5
Wakeham, A.6
Fong, H.E.7
Cheung, C.C.8
Mak, T.W.9
-
9
-
-
84904216760
-
Aryl hydrocarbon receptor control of a disease tolerance defence pathway
-
Bessede A., Gargaro M., Pallotta M.T., Matino D., Servillo G., Brunacci C., Bicciato S., Mazza E.M., Macchiarulo A., Vacca C., et al. Aryl hydrocarbon receptor control of a disease tolerance defence pathway. Nature 2014, 511:184-190.
-
(2014)
Nature
, vol.511
, pp. 184-190
-
-
Bessede, A.1
Gargaro, M.2
Pallotta, M.T.3
Matino, D.4
Servillo, G.5
Brunacci, C.6
Bicciato, S.7
Mazza, E.M.8
Macchiarulo, A.9
Vacca, C.10
-
10
-
-
33646579079
-
Carbon monoxide orchestrates a protective response through PPARgamma
-
Bilban M., Bach F.H., Otterbein S.L., Ifedigbo E., d'Avila J.C., Esterbauer H., Chin B.Y., Usheva A., Robson S.C., Wagner O., Otterbein L.E. Carbon monoxide orchestrates a protective response through PPARgamma. Immunity 2006, 24:601-610.
-
(2006)
Immunity
, vol.24
, pp. 601-610
-
-
Bilban, M.1
Bach, F.H.2
Otterbein, S.L.3
Ifedigbo, E.4
d'Avila, J.C.5
Esterbauer, H.6
Chin, B.Y.7
Usheva, A.8
Robson, S.C.9
Wagner, O.10
Otterbein, L.E.11
-
11
-
-
0016598722
-
Tryptophan 2,3-dioxygenase: a review of the roles of the heme and copper cofactors in catalysis
-
Brady F.O. Tryptophan 2,3-dioxygenase: a review of the roles of the heme and copper cofactors in catalysis. Bioinorg. Chem. 1975, 5:167-182.
-
(1975)
Bioinorg. Chem.
, vol.5
, pp. 167-182
-
-
Brady, F.O.1
-
12
-
-
0036191387
-
The physiology of lactoferrin
-
Brock J.H. The physiology of lactoferrin. Biochem. Cell Biol. 2002, 80:1-6.
-
(2002)
Biochem. Cell Biol.
, vol.80
, pp. 1-6
-
-
Brock, J.H.1
-
13
-
-
0034596874
-
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis
-
Brouard S., Otterbein L.E., Anrather J., Tobiasch E., Bach F.H., Choi A.M., Soares M.P. Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J. Exp. Med. 2000, 192:1015-1026.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1015-1026
-
-
Brouard, S.1
Otterbein, L.E.2
Anrather, J.3
Tobiasch, E.4
Bach, F.H.5
Choi, A.M.6
Soares, M.P.7
-
14
-
-
79957723868
-
Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype
-
Cairo G., Recalcati S., Mantovani A., Locati M. Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype. Trends Immunol. 2011, 32:241-247.
-
(2011)
Trends Immunol.
, vol.32
, pp. 241-247
-
-
Cairo, G.1
Recalcati, S.2
Mantovani, A.3
Locati, M.4
-
15
-
-
84956999697
-
High Affinity Heme Binding to a Heme Regulatory Motif on the Nuclear Receptor Rev-erbbeta Leads to its Degradation and Indirectly Regulates its Interaction with Nuclear Receptor Corepressor
-
Carter E.L., Gupta N., Ragsdale S.W. High Affinity Heme Binding to a Heme Regulatory Motif on the Nuclear Receptor Rev-erbbeta Leads to its Degradation and Indirectly Regulates its Interaction with Nuclear Receptor Corepressor. J. Biol. Chem. 2015, 291:2196-2222.
-
(2015)
J. Biol. Chem.
, vol.291
, pp. 2196-2222
-
-
Carter, E.L.1
Gupta, N.2
Ragsdale, S.W.3
-
17
-
-
84907543940
-
MTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity
-
Cheng S.C., Quintin J., Cramer R.A., Shepardson K.M., Saeed S., Kumar V., Giamarellos-Bourboulis E.J., Martens J.H., Rao N.A., Aghajanirefah A., et al. mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity. Science 2014, 345:1250684.
-
(2014)
Science
, vol.345
, pp. 1250684
-
-
Cheng, S.C.1
Quintin, J.2
Cramer, R.A.3
Shepardson, K.M.4
Saeed, S.5
Kumar, V.6
Giamarellos-Bourboulis, E.J.7
Martens, J.H.8
Rao, N.A.9
Aghajanirefah, A.10
-
18
-
-
34247571886
-
Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning
-
Chin B.Y., Jiang G., Wegiel B., Wang H.J., Macdonald T., Zhang X.C., Gallo D., Cszimadia E., Bach F.H., Lee P.J., Otterbein L.E. Hypoxia-inducible factor 1alpha stabilization by carbon monoxide results in cytoprotective preconditioning. Proc. Natl. Acad. Sci. USA 2007, 104:5109-5114.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 5109-5114
-
-
Chin, B.Y.1
Jiang, G.2
Wegiel, B.3
Wang, H.J.4
Macdonald, T.5
Zhang, X.C.6
Gallo, D.7
Cszimadia, E.8
Bach, F.H.9
Lee, P.J.10
Otterbein, L.E.11
-
19
-
-
84899155461
-
Stress, inflammation, and defense of homeostasis
-
Chovatiya R., Medzhitov R. Stress, inflammation, and defense of homeostasis. Mol. Cell 2014, 54:281-288.
-
(2014)
Mol. Cell
, vol.54
, pp. 281-288
-
-
Chovatiya, R.1
Medzhitov, R.2
-
20
-
-
77956605615
-
Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway
-
Cohen L.A., Gutierrez L., Weiss A., Leichtmann-Bardoogo Y., Zhang D.L., Crooks D.R., Sougrat R., Morgenstern A., Galy B., Hentze M.W., et al. Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. Blood 2010, 116:1574-1584.
-
(2010)
Blood
, vol.116
, pp. 1574-1584
-
-
Cohen, L.A.1
Gutierrez, L.2
Weiss, A.3
Leichtmann-Bardoogo, Y.4
Zhang, D.L.5
Crooks, D.R.6
Sougrat, R.7
Morgenstern, A.8
Galy, B.9
Hentze, M.W.10
-
21
-
-
0037423948
-
HIF-1alpha is essential for myeloid cell-mediated inflammation
-
Cramer T., Yamanishi Y., Clausen B.E., Förster I., Pawlinski R., Mackman N., Haase V.H., Jaenisch R., Corr M., Nizet V., et al. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell 2003, 112:645-657.
-
(2003)
Cell
, vol.112
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Förster, I.4
Pawlinski, R.5
Mackman, N.6
Haase, V.H.7
Jaenisch, R.8
Corr, M.9
Nizet, V.10
-
22
-
-
84894042926
-
Circadian clock proteins and immunity
-
Curtis A.M., Bellet M.M., Sassone-Corsi P., O'Neill L.A. Circadian clock proteins and immunity. Immunity 2014, 40:178-186.
-
(2014)
Immunity
, vol.40
, pp. 178-186
-
-
Curtis, A.M.1
Bellet, M.M.2
Sassone-Corsi, P.3
O'Neill, L.A.4
-
23
-
-
84886654275
-
Tissue-resident macrophages
-
Davies L.C., Jenkins S.J., Allen J.E., Taylor P.R. Tissue-resident macrophages. Nat. Immunol. 2013, 14:986-995.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 986-995
-
-
Davies, L.C.1
Jenkins, S.J.2
Allen, J.E.3
Taylor, P.R.4
-
24
-
-
84861541814
-
Ferroptosis: an iron-dependent form of nonapoptotic cell death
-
Dixon S.J., Lemberg K.M., Lamprecht M.R., Skouta R., Zaitsev E.M., Gleason C.E., Patel D.N., Bauer A.J., Cantley A.M., Yang W.S., et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 2012, 149:1060-1072.
-
(2012)
Cell
, vol.149
, pp. 1060-1072
-
-
Dixon, S.J.1
Lemberg, K.M.2
Lamprecht, M.R.3
Skouta, R.4
Zaitsev, E.M.5
Gleason, C.E.6
Patel, D.N.7
Bauer, A.J.8
Cantley, A.M.9
Yang, W.S.10
-
25
-
-
84868526205
-
Hepcidin and the iron-infection axis
-
Drakesmith H., Prentice A.M. Hepcidin and the iron-infection axis. Science 2012, 338:768-772.
-
(2012)
Science
, vol.338
, pp. 768-772
-
-
Drakesmith, H.1
Prentice, A.M.2
-
26
-
-
76349096031
-
Rapid reprogramming of haemoglobin structure-function exposes multiple dual-antimicrobial potencies
-
Du R., Ho B., Ding J.L. Rapid reprogramming of haemoglobin structure-function exposes multiple dual-antimicrobial potencies. EMBO J. 2010, 29:632-642.
-
(2010)
EMBO J.
, vol.29
, pp. 632-642
-
-
Du, R.1
Ho, B.2
Ding, J.L.3
-
27
-
-
84907546730
-
Hemolysis-induced lethality involves inflammasome activation by heme
-
Dutra F.F., Alves L.S., Rodrigues D., Fernandez P.L., de Oliveira R.B., Golenbock D.T., Zamboni D.S., Bozza M.T. Hemolysis-induced lethality involves inflammasome activation by heme. Proc. Natl. Acad. Sci. USA 2014, 111:E4110-E4118.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. E4110-E4118
-
-
Dutra, F.F.1
Alves, L.S.2
Rodrigues, D.3
Fernandez, P.L.4
de Oliveira, R.B.5
Golenbock, D.T.6
Zamboni, D.S.7
Bozza, M.T.8
-
28
-
-
84931058612
-
The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination
-
Elton L., Carpentier I., Verhelst K., Staal J., Beyaert R. The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination. Immunol. Rev. 2015, 266:208-221.
-
(2015)
Immunol. Rev.
, vol.266
, pp. 208-221
-
-
Elton, L.1
Carpentier, I.2
Verhelst, K.3
Staal, J.4
Beyaert, R.5
-
29
-
-
77958505493
-
Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation
-
Fernandez P.L., Dutra F.F., Alves L., Figueiredo R.T., Mourão-Sa D., Fortes G.B., Bergstrand S., Lönn D., Cevallos R.R., Pereira R.M., et al. Heme amplifies the innate immune response to microbial molecules through spleen tyrosine kinase (Syk)-dependent reactive oxygen species generation. J. Biol. Chem. 2010, 285:32844-32851.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32844-32851
-
-
Fernandez, P.L.1
Dutra, F.F.2
Alves, L.3
Figueiredo, R.T.4
Mourão-Sa, D.5
Fortes, G.B.6
Bergstrand, S.7
Lönn, D.8
Cevallos, R.R.9
Pereira, R.M.10
-
30
-
-
52549119182
-
A central role for free heme in the pathogenesis of severe malaria: the missing link?
-
Ferreira A., Balla J., Jeney V., Balla G., Soares M.P. A central role for free heme in the pathogenesis of severe malaria: the missing link?. J. Mol. Med. 2008, 86:1097-1111.
-
(2008)
J. Mol. Med.
, vol.86
, pp. 1097-1111
-
-
Ferreira, A.1
Balla, J.2
Jeney, V.3
Balla, G.4
Soares, M.P.5
-
31
-
-
79955528559
-
Sickle hemoglobin confers tolerance to Plasmodium infection
-
Ferreira A., Marguti I., Bechmann I., Jeney V., Chora A., Palha N.R., Rebelo S., Henri A., Beuzard Y., Soares M.P. Sickle hemoglobin confers tolerance to Plasmodium infection. Cell 2011, 145:398-409.
-
(2011)
Cell
, vol.145
, pp. 398-409
-
-
Ferreira, A.1
Marguti, I.2
Bechmann, I.3
Jeney, V.4
Chora, A.5
Palha, N.R.6
Rebelo, S.7
Henri, A.8
Beuzard, Y.9
Soares, M.P.10
-
32
-
-
34547120742
-
Characterization of heme as activator of Toll-like receptor 4
-
Figueiredo R.T., Fernandez P.L., Mourao-Sa D.S., Porto B.N., Dutra F.F., Alves L.S., Oliveira M.F., Oliveira P.L., Graça-Souza A.V., Bozza M.T. Characterization of heme as activator of Toll-like receptor 4. J. Biol. Chem. 2007, 282:20221-20229.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20221-20229
-
-
Figueiredo, R.T.1
Fernandez, P.L.2
Mourao-Sa, D.S.3
Porto, B.N.4
Dutra, F.F.5
Alves, L.S.6
Oliveira, M.F.7
Oliveira, P.L.8
Graça-Souza, A.V.9
Bozza, M.T.10
-
33
-
-
11144314814
-
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
-
Flo T.H., Smith K.D., Sato S., Rodriguez D.J., Holmes M.A., Strong R.K., Akira S., Aderem A. Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 2004, 432:917-921.
-
(2004)
Nature
, vol.432
, pp. 917-921
-
-
Flo, T.H.1
Smith, K.D.2
Sato, S.3
Rodriguez, D.J.4
Holmes, M.A.5
Strong, R.K.6
Akira, S.7
Aderem, A.8
-
34
-
-
0035421993
-
Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions
-
Forbes J.R., Gros P. Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions. Trends Microbiol. 2001, 9:397-403.
-
(2001)
Trends Microbiol.
, vol.9
, pp. 397-403
-
-
Forbes, J.R.1
Gros, P.2
-
35
-
-
84858017083
-
Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production
-
Fortes G.B., Alves L.S., de Oliveira R., Dutra F.F., Rodrigues D., Fernandez P.L., Souto-Padron T., De Rosa M.J., Kelliher M., Golenbock D., et al. Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production. Blood 2012, 119:2368-2375.
-
(2012)
Blood
, vol.119
, pp. 2368-2375
-
-
Fortes, G.B.1
Alves, L.S.2
de Oliveira, R.3
Dutra, F.F.4
Rodrigues, D.5
Fernandez, P.L.6
Souto-Padron, T.7
De Rosa, M.J.8
Kelliher, M.9
Golenbock, D.10
-
36
-
-
58149345129
-
Nramp1-functionality increases iNOS expression via repression of IL-10 formation
-
Fritsche G., Nairz M., Werner E.R., Barton H.C., Weiss G. Nramp1-functionality increases iNOS expression via repression of IL-10 formation. Eur. J. Immunol. 2008, 38:3060-3067.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 3060-3067
-
-
Fritsche, G.1
Nairz, M.2
Werner, E.R.3
Barton, H.C.4
Weiss, G.5
-
37
-
-
84937979159
-
Iron homeostasis in host defence and inflammation
-
Ganz T., Nemeth E. Iron homeostasis in host defence and inflammation. Nat. Rev. Immunol. 2015, 15:500-510.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 500-510
-
-
Ganz, T.1
Nemeth, E.2
-
38
-
-
33846016611
-
Monocyte differentiation, activation, and mycobacterial killing are linked to transsulfuration-dependent redox metabolism
-
Garg S., Vitvitsky V., Gendelman H.E., Banerjee R. Monocyte differentiation, activation, and mycobacterial killing are linked to transsulfuration-dependent redox metabolism. J. Biol. Chem. 2006, 281:38712-38720.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 38712-38720
-
-
Garg, S.1
Vitvitsky, V.2
Gendelman, H.E.3
Banerjee, R.4
-
39
-
-
84867740805
-
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
-
Gautier E.L., Shay T., Miller J., Greter M., Jakubzick C., Ivanov S., Helft J., Chow A., Elpek K.G., Gordonov S., et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat. Immunol. 2012, 13:1118-1128. Immunological Genome Consortium.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 1118-1128
-
-
Gautier, E.L.1
Shay, T.2
Miller, J.3
Greter, M.4
Jakubzick, C.5
Ivanov, S.6
Helft, J.7
Chow, A.8
Elpek, K.G.9
Gordonov, S.10
-
40
-
-
33646547951
-
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
-
Gilchrist M., Thorsson V., Li B., Rust A.G., Korb M., Roach J.C., Kennedy K., Hai T., Bolouri H., Aderem A. Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 2006, 441:173-178.
-
(2006)
Nature
, vol.441
, pp. 173-178
-
-
Gilchrist, M.1
Thorsson, V.2
Li, B.3
Rust, A.G.4
Korb, M.5
Roach, J.C.6
Kennedy, K.7
Hai, T.8
Bolouri, H.9
Aderem, A.10
-
41
-
-
84896353280
-
Coupling heme and iron metabolism via ferritin H chain
-
Gozzelino R., Soares M.P. Coupling heme and iron metabolism via ferritin H chain. Antioxid. Redox Signal. 2014, 20:1754-1769.
-
(2014)
Antioxid. Redox Signal.
, vol.20
, pp. 1754-1769
-
-
Gozzelino, R.1
Soares, M.P.2
-
43
-
-
84861845402
-
The updated biology of hypoxia-inducible factor
-
Greer S.N., Metcalf J.L., Wang Y., Ohh M. The updated biology of hypoxia-inducible factor. EMBO J. 2012, 31:2448-2460.
-
(2012)
EMBO J.
, vol.31
, pp. 2448-2460
-
-
Greer, S.N.1
Metcalf, J.L.2
Wang, Y.3
Ohh, M.4
-
44
-
-
0036138169
-
Regulation of cyclooxygenase by the heme-heme oxygenase system in microvessel endothelial cells
-
Haider A., Olszanecki R., Gryglewski R., Schwartzman M.L., Lianos E., Kappas A., Nasjletti A., Abraham N.G. Regulation of cyclooxygenase by the heme-heme oxygenase system in microvessel endothelial cells. J. Pharmacol. Exp. Ther. 2002, 300:188-194.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.300
, pp. 188-194
-
-
Haider, A.1
Olszanecki, R.2
Gryglewski, R.3
Schwartzman, M.L.4
Lianos, E.5
Kappas, A.6
Nasjletti, A.7
Abraham, N.G.8
-
45
-
-
84896366680
-
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages
-
Haldar M., Kohyama M., So A.Y., Kc W., Wu X., Briseño C.G., Satpathy A.T., Kretzer N.M., Arase H., Rajasekaran N.S., et al. Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell 2014, 156:1223-1234.
-
(2014)
Cell
, vol.156
, pp. 1223-1234
-
-
Haldar, M.1
Kohyama, M.2
So, A.Y.3
Kc, W.4
Wu, X.5
Briseño, C.G.6
Satpathy, A.T.7
Kretzer, N.M.8
Arase, H.9
Rajasekaran, N.S.10
-
46
-
-
84864297704
-
One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans
-
Hamza I., Dailey H.A. One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans. Biochim. Biophys. Acta 2012, 1823:1617-1632.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 1617-1632
-
-
Hamza, I.1
Dailey, H.A.2
-
47
-
-
0030608152
-
Ferritins - Molecular Properties, Iron Storage Function and Cellular Regulation
-
Harrison P.M., Arosio P. Ferritins - Molecular Properties, Iron Storage Function and Cellular Regulation. Biochimica et Biophysica Acta - Bioenergetics 1996, 1275:161-203.
-
(1996)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1275
, pp. 161-203
-
-
Harrison, P.M.1
Arosio, P.2
-
48
-
-
84897421970
-
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
-
Hayes J.D., Dinkova-Kostova A.T. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Trends Biochem. Sci. 2014, 39:199-218.
-
(2014)
Trends Biochem. Sci.
, vol.39
, pp. 199-218
-
-
Hayes, J.D.1
Dinkova-Kostova, A.T.2
-
49
-
-
84855548457
-
ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression
-
Hoetzenecker W., Echtenacher B., Guenova E., Hoetzenecker K., Woelbing F., Brück J., Teske A., Valtcheva N., Fuchs K., Kneilling M., et al. ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression. Nat. Med. 2012, 18:128-134.
-
(2012)
Nat. Med.
, vol.18
, pp. 128-134
-
-
Hoetzenecker, W.1
Echtenacher, B.2
Guenova, E.3
Hoetzenecker, K.4
Woelbing, F.5
Brück, J.6
Teske, A.7
Valtcheva, N.8
Fuchs, K.9
Kneilling, M.10
-
50
-
-
27144551314
-
Identification of the receptor scavenging hemopexin-heme complexes
-
Hvidberg V., Maniecki M.B., Jacobsen C., Højrup P., Møller H.J., Moestrup S.K. Identification of the receptor scavenging hemopexin-heme complexes. Blood 2005, 106:2572-2579.
-
(2005)
Blood
, vol.106
, pp. 2572-2579
-
-
Hvidberg, V.1
Maniecki, M.B.2
Jacobsen, C.3
Højrup, P.4
Møller, H.J.5
Moestrup, S.K.6
-
51
-
-
0034623232
-
Feedback control of cyclooxygenase-2 expression through PPARgamma
-
Inoue H., Tanabe T., Umesono K. Feedback control of cyclooxygenase-2 expression through PPARgamma. J. Biol. Chem. 2000, 275:28028-28032.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28028-28032
-
-
Inoue, H.1
Tanabe, T.2
Umesono, K.3
-
52
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 1999, 13:76-86.
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
53
-
-
0034613681
-
Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane
-
Jabado N., Jankowski A., Dougaparsad S., Picard V., Grinstein S., Gros P. Natural resistance to intracellular infections: natural resistance-associated macrophage protein 1 (Nramp1) functions as a pH-dependent manganese transporter at the phagosomal membrane. J. Exp. Med. 2000, 192:1237-1248.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1237-1248
-
-
Jabado, N.1
Jankowski, A.2
Dougaparsad, S.3
Picard, V.4
Grinstein, S.5
Gros, P.6
-
54
-
-
84904015307
-
Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man
-
Jais A., Einwallner E., Sharif O., Gossens K., Lu T.T., Soyal S.M., Medgyesi D., Neureiter D., Paier-Pourani J., Dalgaard K., et al. Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man. Cell 2014, 158:25-40.
-
(2014)
Cell
, vol.158
, pp. 25-40
-
-
Jais, A.1
Einwallner, E.2
Sharif, O.3
Gossens, K.4
Lu, T.T.5
Soyal, S.M.6
Medgyesi, D.7
Neureiter, D.8
Paier-Pourani, J.9
Dalgaard, K.10
-
56
-
-
3343024625
-
Reciprocal regulation of haem biosynthesis and the circadian clock in mammals
-
Kaasik K., Lee C.C. Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature 2004, 430:467-471.
-
(2004)
Nature
, vol.430
, pp. 467-471
-
-
Kaasik, K.1
Lee, C.C.2
-
57
-
-
0028131671
-
Hemoglobin, a newly recognized lipopolysaccharide (LPS)-binding protein that enhances LPS biological activity
-
Kaca W., Roth R.I., Levin J. Hemoglobin, a newly recognized lipopolysaccharide (LPS)-binding protein that enhances LPS biological activity. J. Biol. Chem. 1994, 269:25078-25084.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25078-25084
-
-
Kaca, W.1
Roth, R.I.2
Levin, J.3
-
58
-
-
84942982260
-
Metabolic reprogramming in macrophages and dendritic cells in innate immunity
-
Kelly B., O'Neill L.A. Metabolic reprogramming in macrophages and dendritic cells in innate immunity. Cell Res. 2015, 25:771-784.
-
(2015)
Cell Res.
, vol.25
, pp. 771-784
-
-
Kelly, B.1
O'Neill, L.A.2
-
59
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler T.W., Wakabayashi N., Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 2007, 47:89-116.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
60
-
-
75649138332
-
Expression of stress-response ATF3 is mediated by Nrf2 in astrocytes
-
Kim K.H., Jeong J.Y., Surh Y.J., Kim K.W. Expression of stress-response ATF3 is mediated by Nrf2 in astrocytes. Nucleic Acids Res. 2010, 38:48-59.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 48-59
-
-
Kim, K.H.1
Jeong, J.Y.2
Surh, Y.J.3
Kim, K.W.4
-
61
-
-
84937509395
-
Biological significance and applications of heme c proteins and peptides
-
Kleingardner J.G., Bren K.L. Biological significance and applications of heme c proteins and peptides. Acc. Chem. Res. 2015, 48:1845-1852.
-
(2015)
Acc. Chem. Res.
, vol.48
, pp. 1845-1852
-
-
Kleingardner, J.G.1
Bren, K.L.2
-
62
-
-
13444252281
-
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
-
Knutson M.D., Oukka M., Koss L.M., Aydemir F., Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc. Natl. Acad. Sci. USA 2005, 102:1324-1328.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1324-1328
-
-
Knutson, M.D.1
Oukka, M.2
Koss, L.M.3
Aydemir, F.4
Wessling-Resnick, M.5
-
63
-
-
58249104981
-
Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis
-
Kohyama M., Ise W., Edelson B.T., Wilker P.R., Hildner K., Mejia C., Frazier W.A., Murphy T.L., Murphy K.M. Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis. Nature 2009, 457:318-321.
-
(2009)
Nature
, vol.457
, pp. 318-321
-
-
Kohyama, M.1
Ise, W.2
Edelson, B.T.3
Wilker, P.R.4
Hildner, K.5
Mejia, C.6
Frazier, W.A.7
Murphy, T.L.8
Murphy, K.M.9
-
64
-
-
0029162965
-
Identification of a cis-regulatory element for delta 12-prostaglandin J2-induced expression of the rat heme oxygenase gene
-
Koizumi T., Odani N., Okuyama T., Ichikawa A., Negishi M. Identification of a cis-regulatory element for delta 12-prostaglandin J2-induced expression of the rat heme oxygenase gene. J. Biol. Chem. 1995, 270:21779-21784.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21779-21784
-
-
Koizumi, T.1
Odani, N.2
Okuyama, T.3
Ichikawa, A.4
Negishi, M.5
-
65
-
-
84929186045
-
Macrophages and iron trafficking at the birth and death of red cells
-
Korolnek T., Hamza I. Macrophages and iron trafficking at the birth and death of red cells. Blood 2015, 125:2893-2897.
-
(2015)
Blood
, vol.125
, pp. 2893-2897
-
-
Korolnek, T.1
Hamza, I.2
-
66
-
-
77956256281
-
Redox cycling in iron uptake, efflux, and trafficking
-
Kosman D.J. Redox cycling in iron uptake, efflux, and trafficking. J. Biol. Chem. 2010, 285:26729-26735.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 26729-26735
-
-
Kosman, D.J.1
-
67
-
-
84923357083
-
Homeostasis, inflammation, and disease susceptibility
-
Kotas M.E., Medzhitov R. Homeostasis, inflammation, and disease susceptibility. Cell 2015, 160:816-827.
-
(2015)
Cell
, vol.160
, pp. 816-827
-
-
Kotas, M.E.1
Medzhitov, R.2
-
68
-
-
78650676293
-
Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution
-
Kovtunovych G., Eckhaus M.A., Ghosh M.C., Ollivierre-Wilson H., Rouault T.A. Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution. Blood 2010, 116:6054-6062.
-
(2010)
Blood
, vol.116
, pp. 6054-6062
-
-
Kovtunovych, G.1
Eckhaus, M.A.2
Ghosh, M.C.3
Ollivierre-Wilson, H.4
Rouault, T.A.5
-
69
-
-
0035843134
-
Identification of the haemoglobin scavenger receptor
-
Kristiansen M., Graversen J.H., Jacobsen C., Sonne O., Hoffman H.J., Law S.K., Moestrup S.K. Identification of the haemoglobin scavenger receptor. Nature 2001, 409:198-201.
-
(2001)
Nature
, vol.409
, pp. 198-201
-
-
Kristiansen, M.1
Graversen, J.H.2
Jacobsen, C.3
Sonne, O.4
Hoffman, H.J.5
Law, S.K.6
Moestrup, S.K.7
-
70
-
-
0028981059
-
Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha
-
Kwak E.L., Larochelle D.A., Beaumont C., Torti S.V., Torti F.M. Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha. J. Biol. Chem. 1995, 270:15285-15293.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15285-15293
-
-
Kwak, E.L.1
Larochelle, D.A.2
Beaumont, C.3
Torti, S.V.4
Torti, F.M.5
-
71
-
-
84879694221
-
Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription
-
Lam M.T., Cho H., Lesch H.P., Gosselin D., Heinz S., Tanaka-Oishi Y., Benner C., Kaikkonen M.U., Kim A.S., Kosaka M., et al. Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription. Nature 2013, 498:511-515.
-
(2013)
Nature
, vol.498
, pp. 511-515
-
-
Lam, M.T.1
Cho, H.2
Lesch, H.P.3
Gosselin, D.4
Heinz, S.5
Tanaka-Oishi, Y.6
Benner, C.7
Kaikkonen, M.U.8
Kim, A.S.9
Kosaka, M.10
-
72
-
-
77958023093
-
A central role for free heme in the pathogenesis of severe sepsis
-
Larsen R., Gozzelino R., Jeney V., Tokaji L., Bozza F.A., Japiassú A.M., Bonaparte D., Cavalcante M.M., Chora A., Ferreira A., et al. A central role for free heme in the pathogenesis of severe sepsis. Sci. Transl. Med. 2010, 2:51ra71.
-
(2010)
Sci. Transl. Med.
, vol.2
, pp. 51ra71
-
-
Larsen, R.1
Gozzelino, R.2
Jeney, V.3
Tokaji, L.4
Bozza, F.A.5
Japiassú, A.M.6
Bonaparte, D.7
Cavalcante, M.M.8
Chora, A.9
Ferreira, A.10
-
73
-
-
84948661916
-
Regulation of macrophage development and function in peripheral tissues
-
Lavin Y., Mortha A., Rahman A., Merad M. Regulation of macrophage development and function in peripheral tissues. Nat. Rev. Immunol. 2015, 15:731-744.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 731-744
-
-
Lavin, Y.1
Mortha, A.2
Rahman, A.3
Merad, M.4
-
74
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: enabling diversity with identity
-
Lawrence T., Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat. Rev. Immunol. 2011, 11:750-761.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
75
-
-
0036127426
-
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
-
Lee T.S., Chau L.Y. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med. 2002, 8:240-246.
-
(2002)
Nat. Med.
, vol.8
, pp. 240-246
-
-
Lee, T.S.1
Chau, L.Y.2
-
76
-
-
0038143233
-
Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2
-
Lee T.S., Tsai H.L., Chau L.Y. Induction of heme oxygenase-1 expression in murine macrophages is essential for the anti-inflammatory effect of low dose 15-deoxy-Delta 12,14-prostaglandin J2. J. Biol. Chem. 2003, 278:19325-19330.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19325-19330
-
-
Lee, T.S.1
Tsai, H.L.2
Chau, L.Y.3
-
77
-
-
40349103525
-
Macrophages function as a ferritin iron source for cultured human erythroid precursors
-
Leimberg M.J., Prus E., Konijn A.M., Fibach E. Macrophages function as a ferritin iron source for cultured human erythroid precursors. J. Cell. Biochem. 2008, 103:1211-1218.
-
(2008)
J. Cell. Biochem.
, vol.103
, pp. 1211-1218
-
-
Leimberg, M.J.1
Prus, E.2
Konijn, A.M.3
Fibach, E.4
-
78
-
-
67649289870
-
Physiological and pharmacological features of the novel gasotransmitter: hydrogen sulfide
-
Mancardi D., Penna C., Merlino A., Del Soldato P., Wink D.A., Pagliaro P. Physiological and pharmacological features of the novel gasotransmitter: hydrogen sulfide. Biochim. Biophys. Acta 2009, 1787:864-872.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 864-872
-
-
Mancardi, D.1
Penna, C.2
Merlino, A.3
Del Soldato, P.4
Wink, D.A.5
Pagliaro, P.6
-
79
-
-
84899746695
-
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy
-
Mancias J.D., Wang X., Gygi S.P., Harper J.W., Kimmelman A.C. Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy. Nature 2014, 509:105-109.
-
(2014)
Nature
, vol.509
, pp. 105-109
-
-
Mancias, J.D.1
Wang, X.2
Gygi, S.P.3
Harper, J.W.4
Kimmelman, A.C.5
-
80
-
-
77953713414
-
Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter
-
Marro S., Chiabrando D., Messana E., Stolte J., Turco E., Tolosano E., Muckenthaler M.U. Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter. Haematologica 2010, 95:1261-1268.
-
(2010)
Haematologica
, vol.95
, pp. 1261-1268
-
-
Marro, S.1
Chiabrando, D.2
Messana, E.3
Stolte, J.4
Turco, E.5
Tolosano, E.6
Muckenthaler, M.U.7
-
81
-
-
33750813483
-
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
-
Martinez F.O., Gordon S., Locati M., Mantovani A. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 2006, 177:7303-7311.
-
(2006)
J. Immunol.
, vol.177
, pp. 7303-7311
-
-
Martinez, F.O.1
Gordon, S.2
Locati, M.3
Mantovani, A.4
-
82
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R. Origin and physiological roles of inflammation. Nature 2008, 454:428-435.
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
84
-
-
0036513249
-
Does nitric oxide modulate mitochondrial energy generation and apoptosis?
-
Moncada S., Erusalimsky J.D. Does nitric oxide modulate mitochondrial energy generation and apoptosis?. Nat. Rev. Mol. Cell Biol. 2002, 3:214-220.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 214-220
-
-
Moncada, S.1
Erusalimsky, J.D.2
-
85
-
-
84875261622
-
Indoleamine 2,3 dioxygenase and metabolic control of immune responses
-
Munn D.H., Mellor A.L. Indoleamine 2,3 dioxygenase and metabolic control of immune responses. Trends Immunol. 2013, 34:137-143.
-
(2013)
Trends Immunol.
, vol.34
, pp. 137-143
-
-
Munn, D.H.1
Mellor, A.L.2
-
87
-
-
84879571563
-
Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection
-
Nairz M., Schleicher U., Schroll A., Sonnweber T., Theurl I., Ludwiczek S., Talasz H., Brandacher G., Moser P.L., Muckenthaler M.U., et al. Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection. J. Exp. Med. 2013, 210:855-873.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 855-873
-
-
Nairz, M.1
Schleicher, U.2
Schroll, A.3
Sonnweber, T.4
Theurl, I.5
Ludwiczek, S.6
Talasz, H.7
Brandacher, G.8
Moser, P.L.9
Muckenthaler, M.U.10
-
88
-
-
0026755754
-
Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat
-
Nath K.A., Balla G., Vercellotti G.M., Balla J., Jacob H.S., Levitt M.D., Rosenberg M.E. Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat. J. Clin. Invest. 1992, 90:267-270.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 267-270
-
-
Nath, K.A.1
Balla, G.2
Vercellotti, G.M.3
Balla, J.4
Jacob, H.S.5
Levitt, M.D.6
Rosenberg, M.E.7
-
89
-
-
0034255209
-
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
-
Nathan C., Shiloh M.U. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc. Natl. Acad. Sci. USA 2000, 97:8841-8848.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8841-8848
-
-
Nathan, C.1
Shiloh, M.U.2
-
90
-
-
0028092958
-
Nitric oxide synthases: roles, tolls, and controls
-
Nathan C., Xie Q.W. Nitric oxide synthases: roles, tolls, and controls. Cell 1994, 78:915-918.
-
(1994)
Cell
, vol.78
, pp. 915-918
-
-
Nathan, C.1
Xie, Q.W.2
-
91
-
-
0038662619
-
Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
-
Nemeth E., Valore E.V., Territo M., Schiller G., Lichtenstein A., Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood 2003, 101:2461-2463.
-
(2003)
Blood
, vol.101
, pp. 2461-2463
-
-
Nemeth, E.1
Valore, E.V.2
Territo, M.3
Schiller, G.4
Lichtenstein, A.5
Ganz, T.6
-
92
-
-
70249099576
-
Interdependence of hypoxic and innate immune responses
-
Nizet V., Johnson R.S. Interdependence of hypoxic and innate immune responses. Nat. Rev. Immunol. 2009, 9:609-617.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 609-617
-
-
Nizet, V.1
Johnson, R.S.2
-
93
-
-
17944372665
-
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1
-
Ogawa K., Sun J., Taketani S., Nakajima O., Nishitani C., Sassa S., Hayashi N., Yamamoto M., Shibahara S., Fujita H., Igarashi K. Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J. 2001, 20:2835-2843.
-
(2001)
EMBO J.
, vol.20
, pp. 2835-2843
-
-
Ogawa, K.1
Sun, J.2
Taketani, S.3
Nakajima, O.4
Nishitani, C.5
Sassa, S.6
Hayashi, N.7
Yamamoto, M.8
Shibahara, S.9
Fujita, H.10
Igarashi, K.11
-
94
-
-
84951320286
-
Tissue biology perspective on macrophages
-
Okabe Y., Medzhitov R. Tissue biology perspective on macrophages. Nat. Immunol. 2015, 17:9-17.
-
(2015)
Nat. Immunol.
, vol.17
, pp. 9-17
-
-
Okabe, Y.1
Medzhitov, R.2
-
95
-
-
0034071424
-
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
-
Otterbein L.E., Bach F.H., Alam J., Soares M., Tao Lu H., Wysk M., Davis R.J., Flavell R.A., Choi A.M.K. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat. Med. 2000, 6:422-428.
-
(2000)
Nat. Med.
, vol.6
, pp. 422-428
-
-
Otterbein, L.E.1
Bach, F.H.2
Alam, J.3
Soares, M.4
Tao Lu, H.5
Wysk, M.6
Davis, R.J.7
Flavell, R.A.8
Choi, A.M.K.9
-
96
-
-
2442664117
-
Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase
-
Palacios-Callender M., Quintero M., Hollis V.S., Springett R.J., Moncada S. Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase. Proc. Natl. Acad. Sci. USA 2004, 101:7630-7635.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7630-7635
-
-
Palacios-Callender, M.1
Quintero, M.2
Hollis, V.S.3
Springett, R.J.4
Moncada, S.5
-
97
-
-
34250008488
-
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
-
Pamplona A., Ferreira A., Balla J., Jeney V., Balla G., Epiphanio S., Chora A., Rodrigues C.D., Gregoire I.P., Cunha-Rodrigues M., et al. Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria. Nat. Med. 2007, 13:703-710.
-
(2007)
Nat. Med.
, vol.13
, pp. 703-710
-
-
Pamplona, A.1
Ferreira, A.2
Balla, J.3
Jeney, V.4
Balla, G.5
Epiphanio, S.6
Chora, A.7
Rodrigues, C.D.8
Gregoire, I.P.9
Cunha-Rodrigues, M.10
-
98
-
-
84896339411
-
The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis
-
Pekovic-Vaughan V., Gibbs J., Yoshitane H., Yang N., Pathiranage D., Guo B., Sagami A., Taguchi K., Bechtold D., Loudon A., et al. The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis. Genes Dev. 2014, 28:548-560.
-
(2014)
Genes Dev.
, vol.28
, pp. 548-560
-
-
Pekovic-Vaughan, V.1
Gibbs, J.2
Yoshitane, H.3
Yang, N.4
Pathiranage, D.5
Guo, B.6
Sagami, A.7
Taguchi, K.8
Bechtold, D.9
Loudon, A.10
-
99
-
-
22144492953
-
HIF-1alpha expression regulates the bactericidal capacity of phagocytes
-
Peyssonnaux C., Datta V., Cramer T., Doedens A., Theodorakis E.A., Gallo R.L., Hurtado-Ziola N., Nizet V., Johnson R.S. HIF-1alpha expression regulates the bactericidal capacity of phagocytes. J. Clin. Invest. 2005, 115:1806-1815.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1806-1815
-
-
Peyssonnaux, C.1
Datta, V.2
Cramer, T.3
Doedens, A.4
Theodorakis, E.A.5
Gallo, R.L.6
Hurtado-Ziola, N.7
Nizet, V.8
Johnson, R.S.9
-
100
-
-
8344260568
-
Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species
-
Pham C.G., Bubici C., Zazzeroni F., Papa S., Jones J., Alvarez K., Jayawardena S., De Smaele E., Cong R., Beaumont C., et al. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell 2004, 119:529-542.
-
(2004)
Cell
, vol.119
, pp. 529-542
-
-
Pham, C.G.1
Bubici, C.2
Zazzeroni, F.3
Papa, S.4
Jones, J.5
Alvarez, K.6
Jayawardena, S.7
De Smaele, E.8
Cong, R.9
Beaumont, C.10
-
101
-
-
0032169723
-
Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin
-
Phelan D., Winter G.M., Rogers W.J., Lam J.C., Denison M.S. Activation of the Ah receptor signal transduction pathway by bilirubin and biliverdin. Arch. Biochem. Biophys. 1998, 357:155-163.
-
(1998)
Arch. Biochem. Biophys.
, vol.357
, pp. 155-163
-
-
Phelan, D.1
Winter, G.M.2
Rogers, W.J.3
Lam, J.C.4
Denison, M.S.5
-
102
-
-
0030886381
-
Heme oxygenase 1 is required for mammalian iron reutilization
-
Poss K.D., Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc. Natl. Acad. Sci. USA 1997, 94:10919-10924.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10919-10924
-
-
Poss, K.D.1
Tonegawa, S.2
-
103
-
-
36849084107
-
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta
-
Raghuram S., Stayrook K.R., Huang P., Rogers P.M., Nosie A.K., McClure D.B., Burris L.L., Khorasanizadeh S., Burris T.P., Rastinejad F. Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta. Nat. Struct. Mol. Biol. 2007, 14:1207-1213.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 1207-1213
-
-
Raghuram, S.1
Stayrook, K.R.2
Huang, P.3
Rogers, P.M.4
Nosie, A.K.5
McClure, D.B.6
Burris, L.L.7
Khorasanizadeh, S.8
Burris, T.P.9
Rastinejad, F.10
-
104
-
-
45749113782
-
Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins
-
Rajagopal A., Rao A.U., Amigo J., Tian M., Upadhyay S.K., Hall C., Uhm S., Mathew M.K., Fleming M.D., Paw B.H., et al. Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins. Nature 2008, 453:1127-1131.
-
(2008)
Nature
, vol.453
, pp. 1127-1131
-
-
Rajagopal, A.1
Rao, A.U.2
Amigo, J.3
Tian, M.4
Upadhyay, S.K.5
Hall, C.6
Uhm, S.7
Mathew, M.K.8
Fleming, M.D.9
Paw, B.H.10
-
105
-
-
77749260592
-
Differential regulation of iron homeostasis during human macrophage polarized activation
-
Recalcati S., Locati M., Marini A., Santambrogio P., Zaninotto F., De Pizzol M., Zammataro L., Girelli D., Cairo G. Differential regulation of iron homeostasis during human macrophage polarized activation. Eur. J. Immunol. 2010, 40:824-835.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 824-835
-
-
Recalcati, S.1
Locati, M.2
Marini, A.3
Santambrogio, P.4
Zaninotto, F.5
De Pizzol, M.6
Zammataro, L.7
Girelli, D.8
Cairo, G.9
-
106
-
-
84868540827
-
Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria
-
Regev D., Surolia R., Karki S., Zolak J., Montes-Worboys A., Oliva O., Guroji P., Saini V., Steyn A.J., Agarwal A., Antony V.B. Heme oxygenase-1 promotes granuloma development and protects against dissemination of mycobacteria. Lab. Invest. 2012, 92:1541-1552.
-
(2012)
Lab. Invest.
, vol.92
, pp. 1541-1552
-
-
Regev, D.1
Surolia, R.2
Karki, S.3
Zolak, J.4
Montes-Worboys, A.5
Oliva, O.6
Guroji, P.7
Saini, V.8
Steyn, A.J.9
Agarwal, A.10
Antony, V.B.11
-
107
-
-
4344584558
-
Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide
-
Ricchetti G.A., Williams L.M., Foxwell B.M. Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide. J. Leukoc. Biol. 2004, 76:719-726.
-
(2004)
J. Leukoc. Biol.
, vol.76
, pp. 719-726
-
-
Ricchetti, G.A.1
Williams, L.M.2
Foxwell, B.M.3
-
108
-
-
44849100198
-
NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha
-
Rius J., Guma M., Schachtrup C., Akassoglou K., Zinkernagel A.S., Nizet V., Johnson R.S., Haddad G.G., Karin M. NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature 2008, 453:807-811.
-
(2008)
Nature
, vol.453
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
Johnson, R.S.7
Haddad, G.G.8
Karin, M.9
-
109
-
-
84876906830
-
TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species
-
Roca F.J., Ramakrishnan L. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Cell 2013, 153:521-534.
-
(2013)
Cell
, vol.153
, pp. 521-534
-
-
Roca, F.J.1
Ramakrishnan, L.2
-
110
-
-
66349127141
-
Cyclooxygenases: structural and functional insights
-
Rouzer C.A., Marnett L.J. Cyclooxygenases: structural and functional insights. J. Lipid Res. 2009, 50(Suppl):S29-S34.
-
(2009)
J. Lipid Res.
, vol.50
, pp. S29-S34
-
-
Rouzer, C.A.1
Marnett, L.J.2
-
111
-
-
25444449505
-
Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C
-
Rushworth S.A., Chen X.L., Mackman N., Ogborne R.M., O'Connell M.A. Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C. J. Immunol. 2005, 175:4408-4415.
-
(2005)
J. Immunol.
, vol.175
, pp. 4408-4415
-
-
Rushworth, S.A.1
Chen, X.L.2
Mackman, N.3
Ogborne, R.M.4
O'Connell, M.A.5
-
112
-
-
65249123199
-
Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications
-
Sakamoto K., Iwasaki K., Sugiyama H., Tsuji Y. Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications. Mol. Biol. Cell 2009, 20:1606-1617.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1606-1617
-
-
Sakamoto, K.1
Iwasaki, K.2
Sugiyama, H.3
Tsuji, Y.4
-
113
-
-
84954358205
-
Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases
-
Schneider D.S., Ayres J.S. Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases. Nat. Rev. Immunol. 2008, 8:889-895.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 889-895
-
-
Schneider, D.S.1
Ayres, J.S.2
-
114
-
-
70349448718
-
Heme oxygenase-1 affords protection against noncerebral forms of severe malaria
-
Seixas E., Gozzelino R., Chora A., Ferreira A., Silva G., Larsen R., Rebelo S., Penido C., Smith N.R., Coutinho A., Soares M.P. Heme oxygenase-1 affords protection against noncerebral forms of severe malaria. Proc. Natl. Acad. Sci. USA 2009, 106:15837-15842.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 15837-15842
-
-
Seixas, E.1
Gozzelino, R.2
Chora, A.3
Ferreira, A.4
Silva, G.5
Larsen, R.6
Rebelo, S.7
Penido, C.8
Smith, N.R.9
Coutinho, A.10
Soares, M.P.11
-
115
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
Semenza G.L. Hypoxia-inducible factors in physiology and medicine. Cell 2012, 148:399-408.
-
(2012)
Cell
, vol.148
, pp. 399-408
-
-
Semenza, G.L.1
-
116
-
-
84947983178
-
Conformational control of cofactors in nature - the influence of protein-induced macrocycle distortion on the biological function of tetrapyrroles
-
Senge M.O., MacGowan S.A., O'Brien J.M. Conformational control of cofactors in nature - the influence of protein-induced macrocycle distortion on the biological function of tetrapyrroles. Chem. Commun. (Camb.) 2015, 51:17031-17063.
-
(2015)
Chem. Commun. (Camb.)
, vol.51
, pp. 17031-17063
-
-
Senge, M.O.1
MacGowan, S.A.2
O'Brien, J.M.3
-
117
-
-
43049170080
-
Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection
-
Shiloh M.U., Manzanillo P., Cox J.S. Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection. Cell Host Microbe 2008, 3:323-330.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 323-330
-
-
Shiloh, M.U.1
Manzanillo, P.2
Cox, J.S.3
-
118
-
-
85027948564
-
Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen
-
Siegert I., Schödel J., Nairz M., Schatz V., Dettmer K., Dick C., Kalucka J., Franke K., Ehrenschwender M., Schley G., et al. Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen. Cell Rep. 2015, 13:2048-2055.
-
(2015)
Cell Rep.
, vol.13
, pp. 2048-2055
-
-
Siegert, I.1
Schödel, J.2
Nairz, M.3
Schatz, V.4
Dettmer, K.5
Dick, C.6
Kalucka, J.7
Franke, K.8
Ehrenschwender, M.9
Schley, G.10
-
119
-
-
84879426573
-
Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection
-
Silva-Gomes S., Appelberg R., Larsen R., Soares M.P., Gomes M.S. Heme catabolism by heme oxygenase-1 confers host resistance to Mycobacterium infection. Infect. Immun. 2013, 81:2536-2545.
-
(2013)
Infect. Immun.
, vol.81
, pp. 2536-2545
-
-
Silva-Gomes, S.1
Appelberg, R.2
Larsen, R.3
Soares, M.P.4
Gomes, M.S.5
-
120
-
-
34249809406
-
Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase
-
Singh S., Madzelan P., Banerjee R. Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase. Nat. Prod. Rep. 2007, 24:631-639.
-
(2007)
Nat. Prod. Rep.
, vol.24
, pp. 631-639
-
-
Singh, S.1
Madzelan, P.2
Banerjee, R.3
-
121
-
-
84951922225
-
Red alert: labile heme is an alarmin
-
Soares M.P., Bozza M.T. Red alert: labile heme is an alarmin. Curr. Opin. Immunol. 2016, 38:94-100.
-
(2016)
Curr. Opin. Immunol.
, vol.38
, pp. 94-100
-
-
Soares, M.P.1
Bozza, M.T.2
-
122
-
-
84946068281
-
The Iron age of host-microbe interactions
-
Soares M.P., Weiss G. The Iron age of host-microbe interactions. EMBO Rep. 2015, 16:1482-1500.
-
(2015)
EMBO Rep.
, vol.16
, pp. 1482-1500
-
-
Soares, M.P.1
Weiss, G.2
-
124
-
-
84896935541
-
The aryl hydrocarbon receptor: multitasking in the immune system
-
Stockinger B., Di Meglio P., Gialitakis M., Duarte J.H. The aryl hydrocarbon receptor: multitasking in the immune system. Annu. Rev. Immunol. 2014, 32:403-432.
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 403-432
-
-
Stockinger, B.1
Di Meglio, P.2
Gialitakis, M.3
Duarte, J.H.4
-
125
-
-
0028228808
-
Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states
-
Stone J.R., Marletta M.A. Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states. Biochemistry 1994, 33:5636-5640.
-
(1994)
Biochemistry
, vol.33
, pp. 5636-5640
-
-
Stone, J.R.1
Marletta, M.A.2
-
126
-
-
18644378321
-
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene
-
Sun J., Hoshino H., Takaku K., Nakajima O., Muto A., Suzuki H., Tashiro S., Takahashi S., Shibahara S., Alam J., et al. Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J. 2002, 21:5216-5224.
-
(2002)
EMBO J.
, vol.21
, pp. 5216-5224
-
-
Sun, J.1
Hoshino, H.2
Takaku, K.3
Nakajima, O.4
Muto, A.5
Suzuki, H.6
Tashiro, S.7
Takahashi, S.8
Shibahara, S.9
Alam, J.10
-
127
-
-
1242319573
-
Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network
-
Sun J., Brand M., Zenke Y., Tashiro S., Groudine M., Igarashi K. Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network. Proc. Natl. Acad. Sci. USA 2004, 101:1461-1466.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1461-1466
-
-
Sun, J.1
Brand, M.2
Zenke, Y.3
Tashiro, S.4
Groudine, M.5
Igarashi, K.6
-
128
-
-
77953012548
-
Stress-activated cap'n'collar transcription factors in aging and human disease
-
Sykiotis G.P., Bohmann D. Stress-activated cap'n'collar transcription factors in aging and human disease. Sci. Signal. 2010, 3:re3.
-
(2010)
Sci. Signal.
, vol.3
, pp. re3
-
-
Sykiotis, G.P.1
Bohmann, D.2
-
129
-
-
3142581994
-
Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability
-
Taillé C., El-Benna J., Lanone S., Dang M.C., Ogier-Denis E., Aubier M., Boczkowski J. Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability. J. Biol. Chem. 2004, 279:28681-28688.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28681-28688
-
-
Taillé, C.1
El-Benna, J.2
Lanone, S.3
Dang, M.C.4
Ogier-Denis, E.5
Aubier, M.6
Boczkowski, J.7
-
130
-
-
21844468521
-
Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle
-
Taillé C., El-Benna J., Lanone S., Boczkowski J., Motterlini R. Mitochondrial respiratory chain and NAD(P)H oxidase are targets for the antiproliferative effect of carbon monoxide in human airway smooth muscle. J. Biol. Chem. 2005, 280:25350-25360.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 25350-25360
-
-
Taillé, C.1
El-Benna, J.2
Lanone, S.3
Boczkowski, J.4
Motterlini, R.5
-
131
-
-
33645530745
-
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
-
Thimmulappa R.K., Lee H., Rangasamy T., Reddy S.P., Yamamoto M., Kensler T.W., Biswal S. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J. Clin. Invest. 2006, 116:984-995.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 984-995
-
-
Thimmulappa, R.K.1
Lee, H.2
Rangasamy, T.3
Reddy, S.P.4
Yamamoto, M.5
Kensler, T.W.6
Biswal, S.7
-
132
-
-
0018803696
-
On the haemoprotein character of prostaglandin endoperoxide synthetase
-
van der Ouderaa F.J., Buytenhek M., Slikkerveer F.J., van Dorp D.A. On the haemoprotein character of prostaglandin endoperoxide synthetase. Biochim. Biophys. Acta 1979, 572:29-42.
-
(1979)
Biochim. Biophys. Acta
, vol.572
, pp. 29-42
-
-
van der Ouderaa, F.J.1
Buytenhek, M.2
Slikkerveer, F.J.3
van Dorp, D.A.4
-
133
-
-
0030587961
-
Natural resistance to intracellular infections: Nramp1 encodes a membrane phosphoglycoprotein absent in macrophages from susceptible (Nramp1 D169) mouse strains
-
Vidal S.M., Pinner E., Lepage P., Gauthier S., Gros P. Natural resistance to intracellular infections: Nramp1 encodes a membrane phosphoglycoprotein absent in macrophages from susceptible (Nramp1 D169) mouse strains. J. Immunol. 1996, 157:3559-3568.
-
(1996)
J. Immunol.
, vol.157
, pp. 3559-3568
-
-
Vidal, S.M.1
Pinner, E.2
Lepage, P.3
Gauthier, S.4
Gros, P.5
-
134
-
-
79959559692
-
The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle
-
Warnatz H.J., Schmidt D., Manke T., Piccini I., Sultan M., Borodina T., Balzereit D., Wruck W., Soldatov A., Vingron M., et al. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. J. Biol. Chem. 2011, 286:23521-23532.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 23521-23532
-
-
Warnatz, H.J.1
Schmidt, D.2
Manke, T.3
Piccini, I.4
Sultan, M.5
Borodina, T.6
Balzereit, D.7
Wruck, W.8
Soldatov, A.9
Vingron, M.10
-
135
-
-
84908610651
-
Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation
-
Wegiel B., Larsen R., Gallo D., Chin B.Y., Harris C., Mannam P., Kaczmarek E., Lee P.J., Zuckerbraun B.S., Flavell R., et al. Macrophages sense and kill bacteria through carbon monoxide-dependent inflammasome activation. J. Clin. Invest. 2014, 124:4926-4940.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 4926-4940
-
-
Wegiel, B.1
Larsen, R.2
Gallo, D.3
Chin, B.Y.4
Harris, C.5
Mannam, P.6
Kaczmarek, E.7
Lee, P.J.8
Zuckerbraun, B.S.9
Flavell, R.10
-
136
-
-
0016614384
-
Nutritional immunity. Host's attempt to withold iron from microbial invaders
-
Weinberg E.D. Nutritional immunity. Host's attempt to withold iron from microbial invaders. JAMA 1975, 231:39-41.
-
(1975)
JAMA
, vol.231
, pp. 39-41
-
-
Weinberg, E.D.1
-
137
-
-
84876409224
-
Anaemia in inflammatory rheumatic diseases
-
Weiss G., Schett G. Anaemia in inflammatory rheumatic diseases. Nat. Rev. Rheumatol. 2013, 9:205-215.
-
(2013)
Nat. Rev. Rheumatol.
, vol.9
, pp. 205-215
-
-
Weiss, G.1
Schett, G.2
-
138
-
-
0026766458
-
Iron modulates interferon-gamma effects in the human myelomonocytic cell line THP-1
-
Weiss G., Fuchs D., Hausen A., Reibnegger G., Werner E.R., Werner-Felmayer G., Wachter H. Iron modulates interferon-gamma effects in the human myelomonocytic cell line THP-1. Exp. Hematol. 1992, 20:605-610.
-
(1992)
Exp. Hematol.
, vol.20
, pp. 605-610
-
-
Weiss, G.1
Fuchs, D.2
Hausen, A.3
Reibnegger, G.4
Werner, E.R.5
Werner-Felmayer, G.6
Wachter, H.7
-
139
-
-
0026735580
-
Nitric oxide synthase is a cytochrome P-450 type hemoprotein
-
White K.A., Marletta M.A. Nitric oxide synthase is a cytochrome P-450 type hemoprotein. Biochemistry 1992, 31:6627-6631.
-
(1992)
Biochemistry
, vol.31
, pp. 6627-6631
-
-
White, K.A.1
Marletta, M.A.2
-
140
-
-
84873338198
-
HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis
-
White C., Yuan X., Schmidt P.J., Bresciani E., Samuel T.K., Campagna D., Hall C., Bishop K., Calicchio M.L., Lapierre A., et al. HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis. Cell Metab. 2013, 17:261-270.
-
(2013)
Cell Metab.
, vol.17
, pp. 261-270
-
-
White, C.1
Yuan, X.2
Schmidt, P.J.3
Bresciani, E.4
Samuel, T.K.5
Campagna, D.6
Hall, C.7
Bishop, K.8
Calicchio, M.L.9
Lapierre, A.10
-
141
-
-
84876800337
-
Macrophage biology in development, homeostasis and disease
-
Wynn T.A., Chawla A., Pollard J.W. Macrophage biology in development, homeostasis and disease. Nature 2013, 496:445-455.
-
(2013)
Nature
, vol.496
, pp. 445-455
-
-
Wynn, T.A.1
Chawla, A.2
Pollard, J.W.3
-
142
-
-
0027939931
-
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase
-
Xie Q.W., Kashiwabara Y., Nathan C. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J. Biol. Chem. 1994, 269:4705-4708.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 4705-4708
-
-
Xie, Q.W.1
Kashiwabara, Y.2
Nathan, C.3
-
143
-
-
0032893958
-
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency
-
Yachie A., Niida Y., Wada T., Igarashi N., Kaneda H., Toma T., Ohta K., Kasahara Y., Koizumi S. Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J. Clin. Invest. 1999, 103:129-135.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 129-135
-
-
Yachie, A.1
Niida, Y.2
Wada, T.3
Igarashi, N.4
Kaneda, H.5
Toma, T.6
Ohta, K.7
Kasahara, Y.8
Koizumi, S.9
-
144
-
-
47949112304
-
A novel heme-regulatory motif mediates heme-dependent degradation of the circadian factor period 2
-
Yang J., Kim K.D., Lucas A., Drahos K.E., Santos C.S., Mury S.P., Capelluto D.G., Finkielstein C.V. A novel heme-regulatory motif mediates heme-dependent degradation of the circadian factor period 2. Mol. Cell. Biol. 2008, 28:4697-4711.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4697-4711
-
-
Yang, J.1
Kim, K.D.2
Lucas, A.3
Drahos, K.E.4
Santos, C.S.5
Mury, S.P.6
Capelluto, D.G.7
Finkielstein, C.V.8
-
145
-
-
37249086610
-
Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways
-
Yin L., Wu N., Curtin J.C., Qatanani M., Szwergold N.R., Reid R.A., Waitt G.M., Parks D.J., Pearce K.H., Wisely G.B., Lazar M.A. Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways. Science 2007, 318:1786-1789.
-
(2007)
Science
, vol.318
, pp. 1786-1789
-
-
Yin, L.1
Wu, N.2
Curtin, J.C.3
Qatanani, M.4
Szwergold, N.R.5
Reid, R.A.6
Waitt, G.M.7
Parks, D.J.8
Pearce, K.H.9
Wisely, G.B.10
Lazar, M.A.11
-
146
-
-
0032493445
-
Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase
-
Yu L., Quinn M.T., Cross A.R., Dinauer M.C. Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase. Proc. Natl. Acad. Sci. USA 1998, 95:7993-7998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7993-7998
-
-
Yu, L.1
Quinn, M.T.2
Cross, A.R.3
Dinauer, M.C.4
-
147
-
-
34748886623
-
Heme induces ubiquitination and degradation of the transcription factor Bach1
-
Zenke-Kawasaki Y., Dohi Y., Katoh Y., Ikura T., Ikura M., Asahara T., Tokunaga F., Iwai K., Igarashi K. Heme induces ubiquitination and degradation of the transcription factor Bach1. Mol. Cell. Biol. 2007, 27:6962-6971.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 6962-6971
-
-
Zenke-Kawasaki, Y.1
Dohi, Y.2
Katoh, Y.3
Ikura, T.4
Ikura, M.5
Asahara, T.6
Tokunaga, F.7
Iwai, K.8
Igarashi, K.9
-
148
-
-
84902440210
-
Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation
-
Zhao C., Gillette D.D., Li X., Zhang Z., Wen H. Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J. Biol. Chem. 2014, 289:17020-17029.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 17020-17029
-
-
Zhao, C.1
Gillette, D.D.2
Li, X.3
Zhang, Z.4
Wen, H.5
-
149
-
-
33947628672
-
Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species
-
Zuckerbraun B.S., Chin B.Y., Bilban M., d'Avila J.C., Rao J., Billiar T.R., Otterbein L.E. Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species. FASEB J. 2007, 21:1099-1106.
-
(2007)
FASEB J.
, vol.21
, pp. 1099-1106
-
-
Zuckerbraun, B.S.1
Chin, B.Y.2
Bilban, M.3
d'Avila, J.C.4
Rao, J.5
Billiar, T.R.6
Otterbein, L.E.7
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