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Volumn 9, Issue 8, 2001, Pages 397-403

Divalent-metal transport by NRAMP proteins at the interface of host-pathogen interactions

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; DIVALENT CATION; GLYCOPROTEIN; IRON; IRON BINDING PROTEIN; MANGANESE; MUTANT PROTEIN; PROTEIN NRAMP1; PROTEIN NRAMP2; UNCLASSIFIED DRUG; ZINC;

EID: 0035421993     PISSN: 0966842X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-842X(01)02098-4     Document Type: Review
Times cited : (368)

References (68)
  • 1
    • 0031958788 scopus 로고    scopus 로고
    • Infection genomics: Nramp1 as a major determinant of natural resistance to intracellular infections
    • (1998) Annu. Rev. Med. , vol.49 , pp. 275-287
    • Skamene, E.1
  • 2
    • 0027262167 scopus 로고
    • Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg
    • (1993) Cell , vol.73 , pp. 469-485
    • Vidal, S.M.1
  • 4
    • 0029092312 scopus 로고
    • The Ity/Lsh/Bcg locus: Natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene
    • (1995) J. Exp. Med. , vol.182 , pp. 655-666
    • Vidal, S.1
  • 5
    • 0030017159 scopus 로고    scopus 로고
    • The Bcg/Ity/Lsh locus: Genetic transfer of resistance to infections in C57BL/6J mice transgenic for the Nramp1 Gly169 allele
    • (1996) Infect. Immun. , vol.64 , pp. 2923-2929
    • Govoni, G.1
  • 6
    • 0028099694 scopus 로고
    • Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression
    • (1994) J. Exp. Med. , vol.180 , pp. 1741-1752
    • Cellier, M.1
  • 7
    • 0031051831 scopus 로고    scopus 로고
    • Expression of the human NRAMP1 gene in professional primary phagocytes: Studies in blood cells and in HL-60 promyelocytic leukemia
    • (1997) J. Leuk. Biol. , vol.61 , pp. 96-105
    • Cellier, M.1
  • 9
    • 0033853675 scopus 로고    scopus 로고
    • Linkage of tuberculosis to chromosome 2q35 loci, including NRAMP1, in a large aboriginal Canadian family
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 405-416
    • Greenwood, C.M.1
  • 10
    • 0030767804 scopus 로고    scopus 로고
    • Cell-specific and inducible Nramp1 gene expression in mouse macrophages in vitro and in vivo
    • (1997) J. Leuk. Biol. , vol.62 , pp. 277-286
    • Govoni, G.1
  • 11
    • 0031033088 scopus 로고    scopus 로고
    • Natural resistance to infection with intracellular pathogens: The NRAMP1 protein is recruited to the membrane of the phagosome
    • (1997) J. Exp. Med. , vol.185 , pp. 717-730
    • Gruenheid, S.1
  • 12
    • 0032958593 scopus 로고    scopus 로고
    • Functional expression of Nramp1 in vitro in the murine macrophage line RAW264.7
    • (1999) Infect. Immun. , vol.67 , pp. 2225-2232
    • Govoni, G.1
  • 13
    • 0031730710 scopus 로고    scopus 로고
    • Localisation of NRAMP1 in macrophages: Modulation with activation and infection
    • (1998) J. Cell. Sci. , vol.111 , pp. 2855-2866
    • Searle, S.1
  • 14
    • 0031850526 scopus 로고    scopus 로고
    • Host resistance to intracellular infection: Mutation of natural resistance-associated macrophage protein 1 (NRAMP1) impairs phagosomal acidification
    • (1998) J. Exp. Med. , vol.188 , pp. 351-364
    • Hackam, D.J.1
  • 15
    • 0028962892 scopus 로고
    • Identification and characterization of a second mouse Nramp gene
    • (1995) Genomics , vol.25 , pp. 514-525
    • Gruenheid, S.1
  • 16
    • 0030755366 scopus 로고    scopus 로고
    • Cloning and characterization of a mammalian proton-coupled metal-ion transporter
    • (1997) Nature , vol.388 , pp. 482-488
    • Gunshin, H.1
  • 18
    • 0031127383 scopus 로고    scopus 로고
    • Cloning and characterization of the OsNramp family from Oryza sativa, a new family of membrane proteins possibly implicated in the transport of metal ions
    • (1997) Plant Mol. Biol. , vol.33 , pp. 1085-1092
    • Belouchi, A.1
  • 19
    • 0033773040 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae expresses three functionally distinct homologues of the Nramp family of metal transporters
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7893-7902
    • Portnoy, M.E.1
  • 20
    • 0032841842 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis expresses a novel pH-dependent divalent cation transporter belonging to the Nramp family
    • (1999) J. Exp. Med. , vol.190 , pp. 717-724
    • Agranoff, D.1
  • 21
    • 0028797538 scopus 로고
    • Malvolio, the Drosophila homologue of mouse Nramp1 (Bcg), is expressed in macrophages and in the nervous system and is required for normal taste behaviour
    • (1995) EMBO J. , vol.14 , pp. 3007-3020
    • Rodrigues, V.1
  • 22
    • 0034054897 scopus 로고    scopus 로고
    • Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter
    • (2000) Mol. Microbiol. , vol.35 , pp. 1065-1078
    • Makui, H.1
  • 23
    • 0034193304 scopus 로고    scopus 로고
    • Involvement of NRAMP1 from Arabidopsis thaliana in iron transport
    • (2000) Biochem. J. , vol.347 , pp. 749-755
    • Curie, C.1
  • 25
    • 0029859243 scopus 로고    scopus 로고
    • Bovine natural resistance associated macrophage protein 1 (Nramp1) gene
    • (1996) Genome Res. , vol.6 , pp. 956-964
    • Feng, J.1
  • 28
    • 0034234819 scopus 로고    scopus 로고
    • Heterologous expression, functional characterization and localization of two isoforms of the monkey iron transporter NRAMP2
    • (2000) Biochem. J. , vol.349 , pp. 289-297
    • Zhang, L.1
  • 29
    • 0034680828 scopus 로고    scopus 로고
    • NRAMP2 (DCT1/DMT1) expressed at the plasma membrane transports iron and other divalent cations into a calcein-accessible cytoplasmic pool
    • (2000) J. Biol. Chem. , vol.275 , pp. 35738-35745
    • Picard, V.1
  • 30
    • 0026786329 scopus 로고
    • Topology of the hydrophobic membrane-bound components of the histidine periplasmic permease. Comparison with other members of the family
    • (1992) J. Biol. Chem. , vol.267 , pp. 2329-2336
    • Kerppola, R.E.1    Ames, G.F.2
  • 31
    • 0031933728 scopus 로고    scopus 로고
    • Metal ions suppress the abnormal taste behavior of the Drosophila mutant Malvolio
    • (1998) J. Exp. Biol. , vol.201 , pp. 115-120
    • Orgad, S.1
  • 32
    • 0033166065 scopus 로고    scopus 로고
    • Functional complementation of the Malvolio mutation in the taste pathway of Drosophila melanogaster by the human natural resistance-associated macrophage protein 1 (Nramp1)
    • (1999) J. Exp. Biol. , vol.202 , pp. 1909-1915
    • D'Souza, J.1
  • 34
    • 0033521145 scopus 로고    scopus 로고
    • Yeast SMF1 mediates H(+)-coupled iron uptake with concomitant uncoupled cation currents
    • (1999) J. Biol. Chem. , vol.274 , pp. 35089-35094
    • Chen, X.Z.1
  • 35
    • 0035744950 scopus 로고    scopus 로고
    • Properties of the mammalian and yeast metal-ion transporters DCT1 and Smf1p expressed in Xenopus laevis oocytes
    • (2001) J. Exp. Biol. , vol.204 , pp. 1053-1061
    • Sacher, A.1
  • 36
    • 0030684012 scopus 로고    scopus 로고
    • Functional complementation of the yeast divalent cation transporter family SMF by NRAMP2, a member of the mammalian natural resistance-associated macrophage protein family
    • (1997) J. Biol. Chem. , vol.272 , pp. 28933-28938
    • Pinner, E.1
  • 38
    • 0033564656 scopus 로고    scopus 로고
    • Cellular and subcellular localization of the NRAMP2 iron transporter in the intestinal brush border and regulation by dietary iron
    • (1999) Blood , vol.93 , pp. 4406-4417
    • Canonne-Hergaux, F.1
  • 40
    • 0035138456 scopus 로고    scopus 로고
    • Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
    • (2001) Nat. Genet. , vol.27 , pp. 209-214
    • LaVaute, T.1
  • 42
    • 0034548853 scopus 로고    scopus 로고
    • The NRAMP2/DMT1 iron transporter is induced in the duodenum of microcytic anemia mk mice but is not properly targeted to the intestinal brush border
    • (2000) Blood , vol.96 , pp. 3964-3970
    • Canonne-Hergaux, F.1
  • 44
    • 8244263621 scopus 로고    scopus 로고
    • Iron supplementation moderates but does not cure the Belgrade anemia
    • (1997) Biometals , vol.10 , pp. 65-76
    • Garrick, M.1
  • 46
    • 0033103978 scopus 로고    scopus 로고
    • The iron transport protein NRAMP2 is an integral membrane glycoprotein that colocalizes with transferrin in recycling endosomes
    • (1999) J. Exp. Med. , vol.189 , pp. 831-841
    • Gruenheid, S.1
  • 47
    • 0033984237 scopus 로고    scopus 로고
    • NRAMP2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells
    • (2000) J. Biol. Chem. , vol.275 , pp. 1023-1029
    • Tandy, S.1
  • 48
    • 0031783138 scopus 로고    scopus 로고
    • Evidence for a link between iron metabolism and Nramp1 gene function in innate resistance against Mycobacterium avium
    • (1998) Immunology , vol.95 , pp. 165-168
    • Gomes, M.S.1    Appelberg, R.2
  • 51
    • 0035154676 scopus 로고    scopus 로고
    • Iron transport into Mycobacterium avium-containing phagosomes from an Nramp1(Gly169)-transfected RAW264.7 macrophage cell line
    • (2001) J. Leuk. Biol. , vol.69 , pp. 43-49
    • Kuhn, D.E.1
  • 54
    • 0034613681 scopus 로고    scopus 로고
    • Natural resistance to intracellular infections: Natural resistance-associated macrophage protein 1 (NRAMP1) functions as a pH-dependent manganese transporter at the phagosomal membrane
    • (2000) J. Exp. Med. , vol.192 , pp. 1237-1248
    • Jabado, N.1
  • 58
    • 0037893024 scopus 로고    scopus 로고
    • The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen
    • (2000) Mol. Microbiol. , vol.36 , pp. 1085-1100
    • Kehres, D.G.1
  • 60
    • 0028927433 scopus 로고
    • Role of Salmonella typhimurium Mn-superoxide dismutase (SodA) in protection against early killing by J774 macrophages
    • (1995) Infect. Immun. , vol.63 , pp. 1739-1744
    • Tsolis, R.M.1
  • 61
    • 0025965210 scopus 로고
    • Genetic analysis of superoxide dismutase, the 23 kilodalton antigen of Mycobacterium tuberculosis
    • (1991) Mol. Microbiol. , vol.5 , pp. 381-391
    • Zhang, Y.1
  • 62
    • 0030795074 scopus 로고    scopus 로고
    • Enhanced hydrogen peroxide sensitivity and altered stress protein expression in iron-starved Mycobacterium smegmatis
    • (1997) Biometals , vol.10 , pp. 215-225
    • Lundrigan, M.D.1
  • 63
    • 0028909199 scopus 로고
    • Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited
    • (1995) J. Exp. Med. , vol.181 , pp. 257-270
    • Clemens, D.L.1    Horwitz, M.A.2
  • 64
    • 0031914958 scopus 로고    scopus 로고
    • Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages
    • (1998) J. Immunol. , vol.160 , pp. 1290-1296
    • Schaible, U.E.1
  • 65
    • 0030481130 scopus 로고    scopus 로고
    • Mycobacterium-containing phagosomes are accessible to early endosomes and reflect a transitional state in normal phagosome biogenesis
    • (1996) EMBO J. , vol.15 , pp. 6960-6968
    • Sturgill-Koszycki, S.1
  • 66
    • 0028087919 scopus 로고
    • Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages
    • (1994) J. Immunol. , vol.153 , pp. 2568-2578
    • Xu, S.1
  • 67
    • 0033553440 scopus 로고    scopus 로고
    • A coat protein on phagosomes involved in the intracellular survival of mycobacteria
    • (1999) Cell , vol.97 , pp. 435-447
    • Ferrari, G.1
  • 68
    • 0029858954 scopus 로고    scopus 로고
    • Contribution of TonB- and Feo-mediated iron uptake to growth of Salmonella typhimurium in the mouse
    • (1996) Infect. Immun. , vol.64 , pp. 4549-4556
    • Tsolis, R.M.1


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