Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

Journal of Experimental Medicine

Volumn 210, Issue 5, 2013, Pages 855-873

  Nairz, Manfred ^a   Schleicher, Ulrike ^c   Schroll, Andrea ^a   Sonnweber, Thomas ^a   Theurl, Igor ^a   Ludwiczek, Susanne ^a   Talasz, Heribert ^a   Brandacher, Gerald ^d   Moser, Patrizia L ^b   Muckenthaler, Martina U ^e   Fang, Ferric C ^f   Bogdan, Christian ^c   Weiss, Günter ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b MEDICAL UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFERASIROX; FERRIOXAMINE; FERROPORTIN 1; GAMMA INTERFERON; HEPCIDIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; IRON CHELATING AGENT; NITRIC OXIDE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; CATION TRANSPORT PROTEIN; DEFEROXAMINE; GREEN FLUORESCENT PROTEIN; IRON; METAL TRANSPORTING PROTEIN 1; MUTANT PROTEIN; NFE2L2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BIOACCUMULATION; CELL LEVEL; CONTROLLED STUDY; CYTOKINE RELEASE; HOST RESISTANCE; IMMUNE RESPONSE; INFECTION CONTROL; IRON BALANCE; IRON OVERLOAD; KNOCKOUT GENE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SALMONELLA TYPHIMURIUM; SALMONELLOSIS; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; ANIMAL SALMONELLOSIS; DISEASE RESISTANCE; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; HOMEOSTASIS; HUMAN; IMMUNOLOGY; LIVER CELL; METABOLISM; MICROBIOLOGY; PATHOLOGY; PERITONEUM MACROPHAGE; PROTEIN BINDING; SPLEEN;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; CATION TRANSPORT PROTEINS; DEFEROXAMINE; DISEASE RESISTANCE; FLUORESCENT ANTIBODY TECHNIQUE; GREEN FLUORESCENT PROTEINS; HEPATOCYTES; HOMEOSTASIS; HUMANS; IRON; IRON OVERLOAD; MACROPHAGES, PERITONEAL; MICE; MUTANT PROTEINS; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN BINDING; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; SPLEEN; TRANSFECTION;

MLCS; MLOWN;

EID: 84879571563     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121946     Document Type: Article

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