The physiology of lactoferrin

Biochemistry and Cell Biology

Volumn 80, Issue 1, 2002, Pages 1-6

  Brock, Jeremy H ^a  

^a WESTERN INFIRMARY   (United Kingdom)

Author keywords

Immunology; Infection; Inflammation; Iron; Lactoferrin; Nutrition

Indexed keywords

IRON; PHYSIOLOGY; PROTEINS;

BASIC NATURE;

BIOCHEMISTRY;

AUTOANTIBODY; IRON; IRON BINDING PROTEIN; LACTOFERRIN; PROTEINASE; RIBONUCLEASE;

ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIVIRAL ACTIVITY; BREAST MILK; CARCINOGENESIS; CONFERENCE PAPER; ENZYME ACTIVITY; HUMAN; IMMUNOMODULATION; INFLAMMATION; IRON METABOLISM; NONHUMAN; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; TISSUE DISTRIBUTION; TRANSCRIPTION REGULATION;

ANIMALS; AUTOANTIBODIES; BACTERIA; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; IRON; LACTOFERRIN; NEOPLASMS; PARASITES; VIRUSES;

EID: 0036191387     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o01-212     Document Type: Conference Paper

References (60)

1. Expression of lactoferrin in the kidney: Implications for innate immunity and iron metabolism
2. Lactoferrin and cyclic lactoferricin inhibit the entry of human cytomegalovirus into human fibroblasts
3. A bactericidal effect for human lactoferrin
4. Lactoferrin and transferrin: Functional variations on a common structural framework
5. Lactoferrin: A multifunctional glycoprotein involved in the modulation of the inflammatory process
6. Identification of the bactericidal domain of lactoferrin
7. Lactoferrin in plasma measured by and ELISA technique: Evidence that plasma lactoferrin is an indicator of neutrophil turnover
8. Bactericidal effect of lactoferrin on Legionella pneumophila: Effect of the physiological state of the organism
9. Lactoferrin
10. Antibodies to lactoferrin. A possible link between cow's milk intolerance and autoimmune disease
11. Phagocytosis, killing, lymphocyte-mediated antibacterial activity, serum autoantibodies, and plasma endotoxins in inflammatory bowel disease
12. Inhibition of growth of Pneumocystis carinii by lactoferrins alone and in combination with pyrimethamine, clarithromycin and minocycline
13. Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells
14. Effects of human lactoferrin on NK cell cytotoxicity against haematopoietic and epithelial tumour cells
15. Lactoferrin contains structural motifs of ribonuclease
16. Effect of lactoferrin on Helicobacter felis induced gastritis
17. Multiple molecular forms of human lactoferrin. Identification of a class of lactoferrins that possess ribonuclease activity and lack iron-binding capacity
18. Interaction of tear lipocalin with lysozyme and lactoferrin
19. Antiviral activity of ovo-transferrin discloses an evolutionary strategy for the defensive activites of lactoferrin
20. Bacterial transferrin and lactoferrin receptors
21. Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans
22. The effects of local administration of lactoferrin on inflammation in murine autoimmune and infectious arthritis
23. Sequence specificity and transcriptional activation in the binding of lactoferrin to DNA
24. Characterization of antiviral activity of lactoferrin against hepatitis C virus infection in human cultured cells
25. Interaction of bovine lactoferrin with other proteins of milk whey
26. Lactoferrin: A general review
27. Detection of exon polymorphisms in the human lactoferrin gene
28. Lactoferrin in milk from different species
29. Binding and endocytosis of apo- and holo-lactoferrin by isolated rat hepatocytes
30. Iron overload alters innate and T helper cell responses to Candida albicans in mice
31. Lactoferrin-lipopolysaccharide interactions. Effect on lactoferrin binding to monocyte/macrophage-differentiated HL-60 cells
32. Autoimmune-related pancreatitis is associated with auto-antibodies and a Th1/Th2-type cellular immune response
33. Reduction of the infectivity of Toxoplasma gondii and Eimeria stiedai sporozoites by treatment with bovine lactoferricin
34. Primary iron overload
35. Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae
36. Isolation of lactoferrin cDNA from a human myeloid library and expression of mRNA during normal and leukemic myelopoiesis
37. Supplementation of an adapted formula with bovine lactoferrin: 1 Effect on the infant faecal flora
38. Biological role of lactoferrin
39. Dual interaction of the malaria circumsporozoite protein with the low density lipoprotein receptor-related protein (LRP) and heparan sulfate proteoglycans
40. Bovine lactoferrin peptidic fragments involved in inhibition of herpes simplex virus 1 infection type
41. Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines
42. Purification of a 76-kDa iron-binding protein from human seminal plasma by affinity chromatography specific for ribonuclease: Structural and functional identity with milk lactoferrin
43. Antibacterial activity of 15-residue lactoferricin derivatives
44. Important structural features of 15-residue lactoferrin derivatives and methods for improvement of anit-microbial activity
45. Characterization of mammalian receptors for lactoferrin
46. Tritrichomonas foetus: Iron acquisition from lactoferrin and transferrin
47. Liposomes as possible carriers for lactoferrin in the local treatment of inflammatory diseases
48. Cancer prevention by bovine lactoferrin and underlying mechanisms - A review of experimental and clinical studies
49. Inhibitory effects of bovine lactoferrin on intestinal polyposis in the Apc(Min) mouse
50. The involvement of lactoferrin in the hyposideremia of acute inflammation
51. Lactoferrin, a multifunctional glycoprotein
52. Inhibition of Helicobacter pylori infection by bovine milk glycoconjugates in a BAlb/cA mouse model
53. Restricted spatiotemporal expression of lactoferrin during murine embryonic development
54. Lactoferrin and host defense
55. Acquisition of iron and other nutrients in vivo
56. Antibacterial activity of lactoferrin and a pepsin-derived lactoferrin peptide fragment
57. Ribonuclease, cell-free translation-inhibitory and superoxide radical scavenging activities of the iron-binding protein lactoferrin from bovine milk
58. Apoptosis in human leukemic cells induced by lactoferricin, a bovine milk protein-derived peptide: Involvement of reactive oxygen species
59. Bacterial lactoferrin receptors: Insight from characterizing the Moraxella bovis receptors
60. Interaction of lactoferrin with ceruloplasmin