Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production

Blood

Volumn 119, Issue 10, 2012, Pages 2368-2375

  Fortes, Guilherme B ^a   Alves, Leticia S ^a   De Oliveira, Rosane ^a,b   Dutra, Fabianno F ^a   Rodrigues, Danielle ^a   Fernandez, Patricia L ^c   Souto Padron, Thais ^a   De Rosa, María José ^b   Kelliher, Michelle ^b   Golenbock, Douglas ^b   Chan, Francis K M ^b   Bozza, Marcelo T ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c INSTITUTO DE INVESTIGACIONES CIENTÍFICAS Y SERVICIOS DE ALTA TECNOLOGÍA   (Panama)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; HEME OXYGENASE 1; MYELOID DIFFERENTIATION FACTOR 88; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CELL DEATH; CELL MEMBRANE; CONTROLLED STUDY; CYTOTOXICITY; IRON CHELATION; MACROPHAGE; MOUSE; NECROSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 84858017083     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-08-375303     Document Type: Article

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