-
1
-
-
0026762988
-
Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation
-
Stein M., et al. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 1992, 176:287-292.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 287-292
-
-
Stein, M.1
-
2
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser D.M., Edwards J.P. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 2008, 8:958-969.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
3
-
-
77953268611
-
Alternative activation of macrophages: mechanism and functions
-
Gordon S., Martinez F.O. Alternative activation of macrophages: mechanism and functions. Immunity 2010, 32:593-604.
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
4
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
Gordon S., Taylor P.R. Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 2005, 5:953-964.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
5
-
-
67650485985
-
Alternative activation of macrophages: an immunologic functional perspective
-
Martinez F.O., et al. Alternative activation of macrophages: an immunologic functional perspective. Annu. Rev. Immunol. 2009, 27:451-483.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 451-483
-
-
Martinez, F.O.1
-
6
-
-
0036839143
-
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani A., et al. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol. 2002, 23:549-555.
-
(2002)
Trends Immunol.
, vol.23
, pp. 549-555
-
-
Mantovani, A.1
-
7
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
-
Biswas S.K., Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat. Immunol. 2010, 11:889-896.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
8
-
-
63149088164
-
Trophic macrophages in development and disease
-
Pollard J.W. Trophic macrophages in development and disease. Nat. Rev. Immunol. 2009, 9:259-270.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 259-270
-
-
Pollard, J.W.1
-
9
-
-
33750813483
-
Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression
-
Martinez F.O., et al. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 2006, 177:7303-7311.
-
(2006)
J. Immunol.
, vol.177
, pp. 7303-7311
-
-
Martinez, F.O.1
-
10
-
-
77749260592
-
Differential regulation of iron homeostasis during human macrophage polarized activation
-
Recalcati S., et al. Differential regulation of iron homeostasis during human macrophage polarized activation. Eur. J. Immunol. 2010, 40:824-835.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 824-835
-
-
Recalcati, S.1
-
12
-
-
78449290415
-
The struggle for iron-a metal at the host-pathogen interface
-
Nairz M., et al. The struggle for iron-a metal at the host-pathogen interface. Cell. Microbiol. 2010, 12:1691-1702.
-
(2010)
Cell. Microbiol.
, vol.12
, pp. 1691-1702
-
-
Nairz, M.1
-
13
-
-
64049100955
-
Iron in innate immunity: starve the invaders
-
Ganz T. Iron in innate immunity: starve the invaders. Curr. Opin. Immunol. 2009, 21:63-67.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 63-67
-
-
Ganz, T.1
-
14
-
-
50549086197
-
Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium
-
Nairz M., et al. Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium. Eur. J. Immunol. 2008, 38:1923-1936.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1923-1936
-
-
Nairz, M.1
-
15
-
-
33646345331
-
The iron efflux protein ferroportin regulates the intracellular growth of Salmonella enterica
-
Chlosta S., et al. The iron efflux protein ferroportin regulates the intracellular growth of Salmonella enterica. Infect. Immun. 2006, 74:3065-3067.
-
(2006)
Infect. Immun.
, vol.74
, pp. 3065-3067
-
-
Chlosta, S.1
-
16
-
-
34547863499
-
The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimurium
-
Nairz M., et al. The co-ordinated regulation of iron homeostasis in murine macrophages limits the availability of iron for intracellular Salmonella typhimurium. Cell. Microbiol. 2007, 9:2126-2140.
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 2126-2140
-
-
Nairz, M.1
-
17
-
-
50949104554
-
Iron depletion limits intracellular bacterial growth in macrophages
-
Paradkar P.N., et al. Iron depletion limits intracellular bacterial growth in macrophages. Blood 2008, 112:866-874.
-
(2008)
Blood
, vol.112
, pp. 866-874
-
-
Paradkar, P.N.1
-
18
-
-
33947381278
-
Nramp1 phagocyte intracellular metal withdrawal defense
-
Cellier M.F., et al. Nramp1 phagocyte intracellular metal withdrawal defense. Microbes Infect. 2007, 9:1662-1670.
-
(2007)
Microbes Infect.
, vol.9
, pp. 1662-1670
-
-
Cellier, M.F.1
-
19
-
-
33845878232
-
Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages
-
Olakanmi O., et al. Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages. J. Leukoc. Biol. 2007, 81:195-204.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 195-204
-
-
Olakanmi, O.1
-
20
-
-
0030894809
-
Inappropriately high iron regulatory protein activity in monocytes of patients with genetic hemochromatosis
-
Cairo G., et al. Inappropriately high iron regulatory protein activity in monocytes of patients with genetic hemochromatosis. Blood 1997, 89:2546-2553.
-
(1997)
Blood
, vol.89
, pp. 2546-2553
-
-
Cairo, G.1
-
21
-
-
70449471723
-
Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2
-
Nairz M., et al. Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. Blood 2009, 114:3642-3651.
-
(2009)
Blood
, vol.114
, pp. 3642-3651
-
-
Nairz, M.1
-
22
-
-
68449102680
-
Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease
-
Bacci M., et al. Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease. Am. J. Pathol. 2009, 175:547-556.
-
(2009)
Am. J. Pathol.
, vol.175
, pp. 547-556
-
-
Bacci, M.1
-
23
-
-
33646455658
-
Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation
-
Verreck F.A., et al. Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation. J. Leukoc. Biol. 2006, 79:285-293.
-
(2006)
J. Leukoc. Biol.
, vol.79
, pp. 285-293
-
-
Verreck, F.A.1
-
24
-
-
78149250305
-
Polarization dictates iron handling by inflammatory and alternatively activated macrophages
-
Corna G., et al. Polarization dictates iron handling by inflammatory and alternatively activated macrophages. Haematologica 2010, 95:1814-1822.
-
(2010)
Haematologica
, vol.95
, pp. 1814-1822
-
-
Corna, G.1
-
25
-
-
77955412821
-
Heme oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release
-
Sierra-Filardi E., et al. Heme oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release. Immunobiology 2010, 215:788-795.
-
(2010)
Immunobiology
, vol.215
, pp. 788-795
-
-
Sierra-Filardi, E.1
-
26
-
-
33747338455
-
CD163 positive subsets of blood dendritic cells: the scavenging macrophage receptors CD163 and CD91 are coexpressed on human dendritic cells and monocytes
-
Maniecki M.B., et al. CD163 positive subsets of blood dendritic cells: the scavenging macrophage receptors CD163 and CD91 are coexpressed on human dendritic cells and monocytes. Immunobiology 2006, 211:407-417.
-
(2006)
Immunobiology
, vol.211
, pp. 407-417
-
-
Maniecki, M.B.1
-
27
-
-
38949115537
-
Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation
-
Schaer C.A., et al. Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation. J. Leukoc. Biol. 2008, 83:325-333.
-
(2008)
J. Leukoc. Biol.
, vol.83
, pp. 325-333
-
-
Schaer, C.A.1
-
28
-
-
33751244559
-
Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
-
Qiu A., et al. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell 2006, 127:917-928.
-
(2006)
Cell
, vol.127
, pp. 917-928
-
-
Qiu, A.1
-
29
-
-
63249102414
-
A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis
-
Zhao R., et al. A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis. J. Biol. Chem. 2009, 284:4267-4274.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 4267-4274
-
-
Zhao, R.1
-
30
-
-
73649093148
-
Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages
-
Puig-Kroger A., et al. Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages. Cancer Res. 2009, 69:9395-9403.
-
(2009)
Cancer Res.
, vol.69
, pp. 9395-9403
-
-
Puig-Kroger, A.1
-
31
-
-
68849122521
-
Haptoglobin halts hemoglobin's havoc
-
Kato G.J. Haptoglobin halts hemoglobin's havoc. J. Clin. Invest. 2009, 119:2140-2142.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2140-2142
-
-
Kato, G.J.1
-
32
-
-
77958023093
-
A central role for free heme in the pathogenesis of severe sepsis
-
Larsen R., et al. A central role for free heme in the pathogenesis of severe sepsis. Sci. Transl. Med. 2010, 2:51ra71.
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Larsen, R.1
-
33
-
-
77957331298
-
Hemoglobin-based oxygen carriers: from mechanisms of toxicity and clearance to rational drug design
-
Buehler P.W., et al. Hemoglobin-based oxygen carriers: from mechanisms of toxicity and clearance to rational drug design. Trends Mol. Med. 2010, 16:447-457.
-
(2010)
Trends Mol. Med.
, vol.16
, pp. 447-457
-
-
Buehler, P.W.1
-
34
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene
-
Alam J., et al. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J. Biol. Chem. 1999, 274:26071-26078.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
-
35
-
-
0036127426
-
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
-
Lee T.S., Chau L.Y. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nat. Med. 2002, 8:240-246.
-
(2002)
Nat. Med.
, vol.8
, pp. 240-246
-
-
Lee, T.S.1
Chau, L.Y.2
-
36
-
-
77949525185
-
Mechanisms of cell protection by heme oxygenase-1
-
Gozzelino R., et al. Mechanisms of cell protection by heme oxygenase-1. Annu. Rev. Pharmacol. Toxicol. 2010, 50:323-354.
-
(2010)
Annu. Rev. Pharmacol. Toxicol.
, vol.50
, pp. 323-354
-
-
Gozzelino, R.1
-
38
-
-
65249113865
-
Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants
-
Weis N., et al. Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants. Mol. Biol. Cell 2009, 20:1280-1288.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1280-1288
-
-
Weis, N.1
-
39
-
-
78049442406
-
Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential
-
Paine A., et al. Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem. Pharmacol. 2010, 80:1895-1903.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1895-1903
-
-
Paine, A.1
-
40
-
-
78149250096
-
Glucocorticoid treatment skews human monocyte differentiation into a hemoglobin-clearance phenotype with enhanced heme-iron recycling and antioxidant capacity
-
Vallelian F., et al. Glucocorticoid treatment skews human monocyte differentiation into a hemoglobin-clearance phenotype with enhanced heme-iron recycling and antioxidant capacity. Blood 2010, 116:5347-5356.
-
(2010)
Blood
, vol.116
, pp. 5347-5356
-
-
Vallelian, F.1
-
41
-
-
77954271890
-
Iron regulatory proteins: from molecular mechanisms to drug development
-
Recalcati S., et al. Iron regulatory proteins: from molecular mechanisms to drug development. Antioxid. Redox Signal. 2010, 13:1593-1616.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 1593-1616
-
-
Recalcati, S.1
-
42
-
-
0345688910
-
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages
-
Knutson M.D., et al. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood 2003, 102:4191-4197.
-
(2003)
Blood
, vol.102
, pp. 4191-4197
-
-
Knutson, M.D.1
-
43
-
-
41649110613
-
Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: early mRNA induction by haem, followed by iron-dependent protein expression
-
Delaby C., et al. Sequential regulation of ferroportin expression after erythrophagocytosis in murine macrophages: early mRNA induction by haem, followed by iron-dependent protein expression. Biochem. J. 2008, 411:123-131.
-
(2008)
Biochem. J.
, vol.411
, pp. 123-131
-
-
Delaby, C.1
-
44
-
-
77953713414
-
Heme controls ferroportin1 (FPN1) transcription involving Bach1 Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter
-
Marro S., et al. Heme controls ferroportin1 (FPN1) transcription involving Bach1 Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter. Haematologica 2010, 95:1261-1268.
-
(2010)
Haematologica
, vol.95
, pp. 1261-1268
-
-
Marro, S.1
-
45
-
-
0030886381
-
Heme oxygenase 1 is required for mammalian iron reutilization
-
Poss K.D., Tonegawa S. Heme oxygenase 1 is required for mammalian iron reutilization. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:10919-10924.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 10919-10924
-
-
Poss, K.D.1
Tonegawa, S.2
-
46
-
-
78650676293
-
Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution
-
Kovtunovych G., et al. Dysfunction of the heme recycling system in heme oxygenase 1-deficient mice: effects on macrophage viability and tissue iron distribution. Blood 2010, 116:6054-6062.
-
(2010)
Blood
, vol.116
, pp. 6054-6062
-
-
Kovtunovych, G.1
-
47
-
-
0033161957
-
Haem oxygenase-1 prevents cell death by regulating cellular iron
-
Ferris C.D., et al. Haem oxygenase-1 prevents cell death by regulating cellular iron. Nat. Cell Biol. 1999, 1:152-157.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 152-157
-
-
Ferris, C.D.1
-
48
-
-
38949097546
-
A heme export protein is required for red blood cell differentiation and iron homeostasis
-
Keel S.B., et al. A heme export protein is required for red blood cell differentiation and iron homeostasis. Science 2008, 319:825-828.
-
(2008)
Science
, vol.319
, pp. 825-828
-
-
Keel, S.B.1
-
49
-
-
38849203158
-
Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276
-
Seldon M.P., et al. Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276. J. Immunol. 2007, 179:7840-7851.
-
(2007)
J. Immunol.
, vol.179
, pp. 7840-7851
-
-
Seldon, M.P.1
-
50
-
-
70449394604
-
Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice
-
Wang L., et al. Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. J. Clin. Invest. 2009, 119:3322-3328.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3322-3328
-
-
Wang, L.1
-
51
-
-
53149123286
-
Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation
-
Wang L., et al. Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. J. Immunol. 2008, 181:2723-2731.
-
(2008)
J. Immunol.
, vol.181
, pp. 2723-2731
-
-
Wang, L.1
-
52
-
-
35148828429
-
Hypoxia-inducible factor 1 (HIF-1) pathway
-
Semenza G.L. Hypoxia-inducible factor 1 (HIF-1) pathway. Sci. STKE 2007, 2007:cm8.
-
(2007)
Sci. STKE
, vol.2007
-
-
Semenza, G.L.1
-
53
-
-
77649177217
-
Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis
-
Takeda N., et al. Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. Genes Dev. 2010, 24:491-501.
-
(2010)
Genes Dev.
, vol.24
, pp. 491-501
-
-
Takeda, N.1
-
54
-
-
78649927286
-
Role of ferroportin in macrophage-mediated immunity
-
Johnson E.E., et al. Role of ferroportin in macrophage-mediated immunity. Infect. Immun. 2010, 78:5099-5106.
-
(2010)
Infect. Immun.
, vol.78
, pp. 5099-5106
-
-
Johnson, E.E.1
-
55
-
-
0028059950
-
Iron regulates nitric oxide synthase activity by controlling nuclear transcription
-
Weiss G., et al. Iron regulates nitric oxide synthase activity by controlling nuclear transcription. J. Exp. Med. 1994, 180:969-976.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 969-976
-
-
Weiss, G.1
-
56
-
-
0030911247
-
Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine
-
Melillo G., et al. Functional requirement of the hypoxia-responsive element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferrioxamine. J. Biol. Chem. 1997, 272:12236-12243.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12236-12243
-
-
Melillo, G.1
-
57
-
-
0033563095
-
Central role of transcription factor NF-IL6 for cytokine and iron-mediated regulation of murine inducible nitric oxide synthase expression
-
Dlaska M., Weiss G. Central role of transcription factor NF-IL6 for cytokine and iron-mediated regulation of murine inducible nitric oxide synthase expression. J. Immunol. 1999, 162:6171-6177.
-
(1999)
J. Immunol.
, vol.162
, pp. 6171-6177
-
-
Dlaska, M.1
Weiss, G.2
-
58
-
-
35148896954
-
Phagocyte-derived catecholamines enhance acute inflammatory injury
-
Flierl M.A., et al. Phagocyte-derived catecholamines enhance acute inflammatory injury. Nature 2007, 449:721-725.
-
(2007)
Nature
, vol.449
, pp. 721-725
-
-
Flierl, M.A.1
-
59
-
-
41649103251
-
Catecholamines-crafty weapons in the inflammatory arsenal of immune/inflammatory cells or opening pandora's box?
-
Flierl M.A., et al. Catecholamines-crafty weapons in the inflammatory arsenal of immune/inflammatory cells or opening pandora's box?. Mol. Med. 2008, 14:195-204.
-
(2008)
Mol. Med.
, vol.14
, pp. 195-204
-
-
Flierl, M.A.1
-
60
-
-
84887212575
-
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response
-
Flierl M.A., et al. Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response. PLoS ONE 2009, 4:e4414.
-
(2009)
PLoS ONE
, vol.4
-
-
Flierl, M.A.1
-
61
-
-
73649092092
-
Elucidation of the mechanism by which catecholamine stress hormones liberate iron from the innate immune defense proteins transferrin and lactoferrin
-
Sandrini S.M., et al. Elucidation of the mechanism by which catecholamine stress hormones liberate iron from the innate immune defense proteins transferrin and lactoferrin. J. Bacteriol. 2010, 192:587-594.
-
(2010)
J. Bacteriol.
, vol.192
, pp. 587-594
-
-
Sandrini, S.M.1
-
62
-
-
0037431758
-
Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes
-
Lyte M., et al. Stimulation of Staphylococcus epidermidis growth and biofilm formation by catecholamine inotropes. Lancet 2003, 361:130-135.
-
(2003)
Lancet
, vol.361
, pp. 130-135
-
-
Lyte, M.1
-
63
-
-
33645307685
-
A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18
-
Prasse A., et al. A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18. Am. J. Respir. Crit. Care Med. 2006, 173:781-792.
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.173
, pp. 781-792
-
-
Prasse, A.1
-
64
-
-
0030937832
-
Nitric oxide and macrophage function
-
MacMicking J., et al. Nitric oxide and macrophage function. Annu. Rev. Immunol. 1997, 15:323-350.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 323-350
-
-
MacMicking, J.1
-
65
-
-
33749173797
-
Activation of alveolar macrophages via the alternative pathway in herpesvirus-induced lung fibrosis
-
Mora A.L., et al. Activation of alveolar macrophages via the alternative pathway in herpesvirus-induced lung fibrosis. Am. J. Respir. Cell Mol. Biol. 2006, 35:466-473.
-
(2006)
Am. J. Respir. Cell Mol. Biol.
, vol.35
, pp. 466-473
-
-
Mora, A.L.1
-
66
-
-
0038156301
-
The heme-heme oxygenase system: a molecular switch in wound healing
-
Wagener F.A., et al. The heme-heme oxygenase system: a molecular switch in wound healing. Blood 2003, 102:521-528.
-
(2003)
Blood
, vol.102
, pp. 521-528
-
-
Wagener, F.A.1
-
67
-
-
79952279351
-
The heme-heme oxygenase system in wound healing; implications for scar formation
-
Wagener F.A., et al. The heme-heme oxygenase system in wound healing; implications for scar formation. Curr. Drug Targets 2010, 11:1571-1585.
-
(2010)
Curr. Drug Targets
, vol.11
, pp. 1571-1585
-
-
Wagener, F.A.1
-
68
-
-
79952135247
-
An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice
-
Sindrilaru A., et al. An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J. Clin. Invest. 2011, 121:985-997.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 985-997
-
-
Sindrilaru, A.1
-
69
-
-
77955607931
-
Ferroportin and iron regulation in breast cancer progression and prognosis
-
Pinnix Z.K., et al. Ferroportin and iron regulation in breast cancer progression and prognosis. Sci. Transl. Med. 2010, 2:43ra56.
-
(2010)
Sci. Transl. Med.
, vol.2
-
-
Pinnix, Z.K.1
-
70
-
-
79953761269
-
An outsider's perspective-ecotaxis revisited: an integrative review of cancer environment, iron and immune system cells
-
de Sousa M. An outsider's perspective-ecotaxis revisited: an integrative review of cancer environment, iron and immune system cells. Integr. Biol. (Camb.) 2011, 3:343-349.
-
(2011)
Integr. Biol. (Camb.)
, vol.3
, pp. 343-349
-
-
de Sousa, M.1
-
71
-
-
77957802876
-
Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein
-
Choi Y.K., et al. Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein. J. Biol. Chem. 2010, 285:32116-32125.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32116-32125
-
-
Choi, Y.K.1
-
72
-
-
65449130775
-
The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1
-
Wang X.M., et al. The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1. J. Immunol. 2009, 182:3809-3818.
-
(2009)
J. Immunol.
, vol.182
, pp. 3809-3818
-
-
Wang, X.M.1
-
73
-
-
0034071424
-
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
-
Otterbein L.E., et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat. Med. 2000, 6:422-428.
-
(2000)
Nat. Med.
, vol.6
, pp. 422-428
-
-
Otterbein, L.E.1
-
74
-
-
33750461301
-
CD163-Mediated hemoglobin-heme uptake activates macrophage HO-1, providing an antiinflammatory function
-
Abraham N.G., Drummond G. CD163-Mediated hemoglobin-heme uptake activates macrophage HO-1, providing an antiinflammatory function. Circ. Res. 2006, 99:911-914.
-
(2006)
Circ. Res.
, vol.99
, pp. 911-914
-
-
Abraham, N.G.1
Drummond, G.2
-
75
-
-
33749322644
-
Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts
-
Nakahira K., et al. Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J. Exp. Med. 2006, 203:2377-2389.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2377-2389
-
-
Nakahira, K.1
-
76
-
-
28444478749
-
Leishmania pifanoi amastigotes avoid macrophage production of superoxide by inducing heme degradation
-
Pham N.K., et al. Leishmania pifanoi amastigotes avoid macrophage production of superoxide by inducing heme degradation. Infect. Immun. 2005, 73:8322-8333.
-
(2005)
Infect. Immun.
, vol.73
, pp. 8322-8333
-
-
Pham, N.K.1
-
77
-
-
33750624054
-
Heme oxygenase and cyclooxygenase in the central nervous system: a functional interplay
-
Mancuso C., et al. Heme oxygenase and cyclooxygenase in the central nervous system: a functional interplay. J. Neurosci. Res. 2006, 84:1385-1391.
-
(2006)
J. Neurosci. Res.
, vol.84
, pp. 1385-1391
-
-
Mancuso, C.1
-
78
-
-
70349581878
-
Macrophage diversity and polarization in atherosclerosis: a question of balance
-
Mantovani A., et al. Macrophage diversity and polarization in atherosclerosis: a question of balance. Arterioscler. Thromb. Vasc. Biol. 2009, 29:1419-1423.
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 1419-1423
-
-
Mantovani, A.1
-
79
-
-
34548429748
-
Macrophage iron, hepcidin, and atherosclerotic plaque stability
-
Sullivan J.L. Macrophage iron, hepcidin, and atherosclerotic plaque stability. Exp. Biol. Med. (Maywood) 2007, 232:1014-1020.
-
(2007)
Exp. Biol. Med. (Maywood)
, vol.232
, pp. 1014-1020
-
-
Sullivan, J.L.1
-
80
-
-
34250831495
-
Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis
-
Orozco L.D., et al. Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis. Circ. Res. 2007, 100:1703-1711.
-
(2007)
Circ. Res.
, vol.100
, pp. 1703-1711
-
-
Orozco, L.D.1
-
81
-
-
4644310922
-
Iron-source preference of Staphylococcus aureus infections
-
Skaar E.P., et al. Iron-source preference of Staphylococcus aureus infections. Science 2004, 305:1626-1628.
-
(2004)
Science
, vol.305
, pp. 1626-1628
-
-
Skaar, E.P.1
-
82
-
-
33745484154
-
Control of iron metabolism in Mycobacterium tuberculosis
-
Rodriguez G.M. Control of iron metabolism in Mycobacterium tuberculosis. Trends Microbiol. 2006, 14:320-327.
-
(2006)
Trends Microbiol.
, vol.14
, pp. 320-327
-
-
Rodriguez, G.M.1
-
83
-
-
0032841842
-
Mycobacterium tuberculosis expresses a novel pH-dependent divalent cation transporter belonging to the Nramp family
-
Agranoff D., et al. Mycobacterium tuberculosis expresses a novel pH-dependent divalent cation transporter belonging to the Nramp family. J. Exp. Med. 1999, 190:717-724.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 717-724
-
-
Agranoff, D.1
-
84
-
-
0035209779
-
SLC11A1 (formerly NRAMP1) and disease resistance
-
Blackwell J.M., et al. SLC11A1 (formerly NRAMP1) and disease resistance. Cell. Microbiol. 2001, 3:773-784.
-
(2001)
Cell. Microbiol.
, vol.3
, pp. 773-784
-
-
Blackwell, J.M.1
-
85
-
-
58149291350
-
Leishmania donovani depletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth
-
Das N.K., et al. Leishmania donovani depletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth. Cell. Microbiol. 2009, 11:83-94.
-
(2009)
Cell. Microbiol.
, vol.11
, pp. 83-94
-
-
Das, N.K.1
-
86
-
-
38049186501
-
Iron acquisition within host cells and the pathogenicity of Leishmania
-
Huynh C., Andrews N.W. Iron acquisition within host cells and the pathogenicity of Leishmania. Cell. Microbiol. 2008, 10:293-300.
-
(2008)
Cell. Microbiol.
, vol.10
, pp. 293-300
-
-
Huynh, C.1
Andrews, N.W.2
-
87
-
-
0038579427
-
Bacterial iron homeostasis
-
Andrews S.C., et al. Bacterial iron homeostasis. FEMS Microbiol. Rev. 2003, 27:215-237.
-
(2003)
FEMS Microbiol. Rev.
, vol.27
, pp. 215-237
-
-
Andrews, S.C.1
-
88
-
-
22744439747
-
Ironing out the problem: new mechanisms of iron homeostasis
-
Masse E., Arguin M. Ironing out the problem: new mechanisms of iron homeostasis. Trends Biochem. Sci. 2005, 30:462-468.
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 462-468
-
-
Masse, E.1
Arguin, M.2
-
89
-
-
34447117474
-
Hepcidin regulation: ironing out the details
-
De Domenico I., et al. Hepcidin regulation: ironing out the details. J. Clin. Invest. 2007, 117:1755-1758.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1755-1758
-
-
De Domenico, I.1
-
90
-
-
67349115201
-
Iron metabolism in the anemia of chronic disease
-
Weiss G. Iron metabolism in the anemia of chronic disease. Biochim. Biophys. Acta 2009, 1790:682-693.
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, pp. 682-693
-
-
Weiss, G.1
-
91
-
-
70449729523
-
Stress hormones: physiological stress and regulation of metabolism
-
Kyrou I., Tsigos C. Stress hormones: physiological stress and regulation of metabolism. Curr. Opin. Pharmacol. 2009, 9:787-793.
-
(2009)
Curr. Opin. Pharmacol.
, vol.9
, pp. 787-793
-
-
Kyrou, I.1
Tsigos, C.2
|