The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

Trends in Biochemical Sciences

Volumn 39, Issue 4, 2014, Pages 199-218

  Hayes, John D ^a   Dinkova Kostova, Albena T ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Fatty acid oxidation; Glutathione; GSK 3; Keap1; NADPH; Nrf2; Oxidative stress; Pentose phosphate pathway; Purine synthesis; Thioredoxin; TrCP

Indexed keywords

CR6 INTERACTING FACTOR 1; GLYCOGEN SYNTHASE KINASE 3BETA; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MICRORNA; PENTOSE PHOSPHATE; PROTEASOME; PURINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REGULATOR PROTEIN; RING FINGER PROTEIN; RING FINGER PROTEIN 4; SEVEN IN ABSENTIA HOMOLOG 2 PROTEIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; BRCA1 PROTEIN; GLUTAMINE; GLUTATHIONE DISULFIDE; GLUTATHIONE REDUCTASE; GLYCOGEN SYNTHASE KINASE 3; LIPID;

ACETYLATION; AUTOPHAGY; BINDING AFFINITY; CELL PROTECTION; DETOXIFICATION; DNA REPAIR; ENZYME INDUCTION; EPIGENETICS; FATTY ACID OXIDATION; GLUCONEOGENESIS; HUMAN; LIPID METABOLISM; LIPOGENESIS; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; NONHUMAN; NRF2 GENE; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PURINE SYNTHESIS; REGULATORY MECHANISM; REVIEW; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; AMINO ACID SYNTHESIS; CELL FUNCTION; DRUG METABOLISM; GENE CONTROL; OXIDATION REDUCTION POTENTIAL; PROTEIN ACETYLATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN MOTIF; TRANSLATION REGULATION;

GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIA; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION;

EID: 84897421970     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2014.02.002     Document Type: Review

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