-
1
-
-
79953046719
-
The inflammasome NLRs in immunity, inflammation, and associated diseases
-
Davis, B. K., Wen, H., and Ting, J. P. (2011) The inflammasome NLRs in immunity, inflammation, and associated diseases. Annu. Rev. Immunol. 29, 707-735
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 707-735
-
-
Davis, B.K.1
Wen, H.2
Ting, J.P.3
-
2
-
-
84855989829
-
Inflammasomes in health and disease
-
Strowig, T., Henao-Mejia, J., Elinav, E., and Flavell, R. (2012) Inflammasomes in health and disease. Nature 481, 278-286
-
(2012)
Nature
, vol.481
, pp. 278-286
-
-
Strowig, T.1
Henao-Mejia, J.2
Elinav, E.3
Flavell, R.4
-
3
-
-
77950362382
-
The inflammasomes
-
Schroder, K., and Tschopp, J. (2010) The inflammasomes. Cell 140, 821-832
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
4
-
-
84869504451
-
Inflammasomes and their roles in health and disease
-
Lamkanfi, M., and Dixit, V. M. (2012) Inflammasomes and their roles in health and disease. Annu. Rev. Cell Dev. Biol. 28, 137-161
-
(2012)
Annu. Rev. Cell Dev. Biol.
, vol.28
, pp. 137-161
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
5
-
-
84875542536
-
Recognition of bacteria by inflammasomes
-
von Moltke, J., Ayres, J. S., Kofoed, E. M., Chavarría-Smith, J., and Vance, R. E. (2013) Recognition of bacteria by inflammasomes. Annu. Rev. Immunol. 31, 73-106
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 73-106
-
-
Von Moltke, J.1
Ayres, J.S.2
Kofoed, E.M.3
Chavarría-Smith, J.4
Vance, R.E.5
-
6
-
-
84858688293
-
Regulation of inflammasome signaling
-
Rathinam, V. A., Vanaja, S. K., and Fitzgerald, K. A. (2012) Regulation of inflammasome signaling. Nat. Immunol. 13, 333-342
-
(2012)
Nat. Immunol.
, vol.13
, pp. 333-342
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Fitzgerald, K.A.3
-
7
-
-
84884332722
-
Mechanisms of NOD-like receptor-associated inflammasome activation
-
Wen, H., Miao, E. A., and Ting, J. P. (2013) Mechanisms of NOD-like receptor-associated inflammasome activation. Immunity 39, 432-441
-
(2013)
Immunity
, vol.39
, pp. 432-441
-
-
Wen, H.1
Miao, E.A.2
Ting, J.P.3
-
8
-
-
84856857478
-
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
-
Menu, P., Mayor, A., Zhou, R., Tardivel, A., Ichijo, H., Mori, K., and Tschopp, J. (2012) ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death Dis. 3, e261
-
(2012)
Cell Death Dis.
, vol.3
-
-
Menu, P.1
Mayor, A.2
Zhou, R.3
Tardivel, A.4
Ichijo, H.5
Mori, K.6
Tschopp, J.7
-
9
-
-
84870508924
-
2+ and cAMP
-
2+ and cAMP. Nature 492, 123-127
-
(2012)
Nature
, vol.492
, pp. 123-127
-
-
Lee, G.S.1
Subramanian, N.2
Kim, A.I.3
Aksentijevich, I.4
Goldbach-Mansky, R.5
Sacks, D.B.6
Germain, R.N.7
Kastner, D.L.8
Chae, J.J.9
-
10
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami, T., Ockinger, J., Yu, J., Byles, V., McColl, A., Hofer, A. M., and Horng, T. (2012) Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc. Natl. Acad. Sci. U.S.A. 109, 11282-11287
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
Horng, T.7
-
11
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou, R., Yazdi, A. S., Menu, P., and Tschopp, J. (2011) A role for mitochondria in NLRP3 inflammasome activation. Nature 469, 221-225
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
12
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
Wen, H., Gris, D., Lei, Y., Jha, S., Zhang, L., Huang, M. T., Brickey, W. J., and Ting, J. P. (2011) Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat. Immunol. 12, 408-415
-
(2011)
Nat. Immunol.
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.6
Brickey, W.J.7
Ting, J.P.8
-
13
-
-
84882614243
-
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation
-
Iyer, S. S., He, Q., Janczy, J. R., Elliott, E. I., Zhong, Z., Olivier, A. K., Sadler, J. J., Knepper-Adrian, V., Han, R., Qiao, L., Eisenbarth, S. C., Nauseef, W. M., Cassel, S. L., and Sutterwala, F. S. (2013) Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. Immunity 39, 311-323
-
(2013)
Immunity
, vol.39
, pp. 311-323
-
-
Iyer, S.S.1
He, Q.2
Janczy, J.R.3
Elliott, E.I.4
Zhong, Z.5
Olivier, A.K.6
Sadler, J.J.7
Knepper-Adrian, V.8
Han, R.9
Qiao, L.10
Eisenbarth, S.C.11
Nauseef, W.M.12
Cassel, S.L.13
Sutterwala, F.S.14
-
14
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira, K., Haspel, J. A., Rathinam, V. A., Lee, S. J., Dolinay, T., Lam, H. C., Englert, J. A., Rabinovitch, M., Cernadas, M., Kim, H. P., Fitzgerald, K. A., Ryter, S. W., and Choi, A. M. (2011) Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol. 12, 222-230
-
(2011)
Nat. Immunol.
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
15
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada, K., Crother, T. R., Karlin, J., Dagvadorj, J., Chiba, N., Chen, S., Ramanujan, V. K., Wolf, A. J., Vergnes, L., Ojcius, D. M., Rentsendorj, A., Vargas, M., Guerrero, C., Wang, Y., Fitzgerald, K. A., Underhill, D. M., Town, T., and Arditi, M. (2012) Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 36, 401-414
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
Ramanujan, V.K.7
Wolf, A.J.8
Vergnes, L.9
Ojcius, D.M.10
Rentsendorj, A.11
Vargas, M.12
Guerrero, C.13
Wang, Y.14
Fitzgerald, K.A.15
Underhill, D.M.16
Town, T.17
Arditi, M.18
-
16
-
-
84885944468
-
The emerging role of the Nrf2-Keap1 signaling pathway in cancer
-
Jaramillo, M. C., and Zhang, D. D. (2013) The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes Dev. 27, 2179-2191
-
(2013)
Genes Dev.
, vol.27
, pp. 2179-2191
-
-
Jaramillo, M.C.1
Zhang, D.D.2
-
17
-
-
84867034260
-
Role of nrf2 in oxidative stress and toxicity
-
Ma, Q. (2013) Role of nrf2 in oxidative stress and toxicity. Annu. Rev. Pharmacol. Toxicol. 53, 401-426
-
(2013)
Annu. Rev. Pharmacol. Toxicol.
, vol.53
, pp. 401-426
-
-
Ma, Q.1
-
18
-
-
84878572136
-
Toward clinical application of the Keap1-Nrf2 pathway
-
Suzuki, T., Motohashi, H., and Yamamoto, M. (2013) Toward clinical application of the Keap1-Nrf2 pathway. Trends Pharmacol. Sci. 34, 340-346
-
(2013)
Trends Pharmacol. Sci.
, vol.34
, pp. 340-346
-
-
Suzuki, T.1
Motohashi, H.2
Yamamoto, M.3
-
19
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
Kensler, T. W., Wakabayashi, N., and Biswal, S. (2007) Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 47, 89-116
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
20
-
-
33645530745
-
Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis
-
Thimmulappa, R. K., Lee, H., Rangasamy, T., Reddy, S. P., Yamamoto, M., Kensler, T. W., and Biswal, S. (2006) Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J. Clin. Invest. 116, 984-995
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 984-995
-
-
Thimmulappa, R.K.1
Lee, H.2
Rangasamy, T.3
Reddy, S.P.4
Yamamoto, M.5
Kensler, T.W.6
Biswal, S.7
-
21
-
-
80054713581
-
Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis
-
Kong, X., Thimmulappa, R., Craciun, F., Harvey, C., Singh, A., Kombairaju, P., Reddy, S. P., Remick, D., and Biswal, S. (2011) Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis. Am. J. Respir. Crit. Care Med. 184, 928-938
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.184
, pp. 928-938
-
-
Kong, X.1
Thimmulappa, R.2
Craciun, F.3
Harvey, C.4
Singh, A.5
Kombairaju, P.6
Reddy, S.P.7
Remick, D.8
Biswal, S.9
-
22
-
-
22344438250
-
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
-
DOI 10.1084/jem.20050538
-
Rangasamy, T., Guo, J., Mitzner, W. A., Roman, J., Singh, A., Fryer, A. D., Yamamoto, M., Kensler, T. W., Tuder, R. M., Georas, S. N., and Biswal, S. (2005) Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J. Exp. Med. 202, 47-59 (Pubitemid 41002909)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.1
, pp. 47-59
-
-
Rangasamy, T.1
Guo, J.2
Mitzner, W.A.3
Roman, J.4
Singh, A.5
Fryer, A.D.6
Yamamoto, M.7
Kensler, T.W.8
Tuder, R.M.9
Georas, S.N.10
Biswal, S.11
-
23
-
-
58449116694
-
Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease
-
Cho, H. Y., Imani, F., Miller-DeGraff, L., Walters, D., Melendi, G. A., Yamamoto, M., Polack, F. P., and Kleeberger, S. R. (2009) Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease. Am. J. Respir. Crit. Care Med. 179, 138-150
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
, pp. 138-150
-
-
Cho, H.Y.1
Imani, F.2
Miller-DeGraff, L.3
Walters, D.4
Melendi, G.A.5
Yamamoto, M.6
Polack, F.P.7
Kleeberger, S.R.8
-
24
-
-
70449723401
-
Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice
-
Reddy, N. M., Suryanarayana, V., Kalvakolanu, D. V., Yamamoto, M., Kensler, T. W., Hassoun, P. M., Kleeberger, S. R., and Reddy, S. P. (2009) Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice. J. Immunol. 183, 4601-4608
-
(2009)
J. Immunol.
, vol.183
, pp. 4601-4608
-
-
Reddy, N.M.1
Suryanarayana, V.2
Kalvakolanu, D.V.3
Yamamoto, M.4
Kensler, T.W.5
Hassoun, P.M.6
Kleeberger, S.R.7
Reddy, S.P.8
-
25
-
-
84863558315
-
Oxidative stress fuels Trypanosoma cruzi infection in mice
-
Paiva, C. N., Feijó, D. F., Dutra, F. F., Carneiro, V. C., Freitas, G. B., Alves, L. S., Mesquita, J., Fortes, G. B., Figueiredo, R. T., Souza, H. S., Fantappié, M. R., Lannes-Vieira, J., and Bozza, M. T. (2012) Oxidative stress fuels Trypanosoma cruzi infection in mice. J. Clin. Invest. 122, 2531-2542
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2531-2542
-
-
Paiva, C.N.1
Feijó, D.F.2
Dutra, F.F.3
Carneiro, V.C.4
Freitas, G.B.5
Alves, L.S.6
Mesquita, J.7
Fortes, G.B.8
Figueiredo, R.T.9
Souza, H.S.10
Fantappié, M.R.11
Lannes-Vieira, J.12
Bozza, M.T.13
-
26
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
DOI 10.1172/JCI200421146
-
Rangasamy, T., Cho, C. Y., Thimmulappa, R. K., Zhen, L., Srisuma, S. S., Kensler, T. W., Yamamoto, M., Petrache, I., Tuder, R. M., and Biswal, S. (2004) Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J. Clin. Invest. 114, 1248-1259 (Pubitemid 40385296)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.9
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
27
-
-
56849124834
-
Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates apoE-mediated atherosclerosis in mice
-
Sussan, T. E., Jun, J., Thimmulappa, R., Bedja, D., Antero, M., Gabrielson, K. L., Polotsky, V. Y., and Biswal, S. (2008) Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates apoE-mediated atherosclerosis in mice. PLoS ONE 3, e3791
-
(2008)
PLoS ONE
, vol.3
-
-
Sussan, T.E.1
Jun, J.2
Thimmulappa, R.3
Bedja, D.4
Antero, M.5
Gabrielson, K.L.6
Polotsky, V.Y.7
Biswal, S.8
-
28
-
-
78650913866
-
NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection
-
Barajas, B., Che, N., Yin, F., Rowshanrad, A., Orozco, L. D., Gong, K. W., Wang, X., Castellani, L. W., Reue, K., Lusis, A. J., and Araujo, J. A. (2011) NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arterioscler. Thromb. Vasc. Biol. 31, 58-66
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, pp. 58-66
-
-
Barajas, B.1
Che, N.2
Yin, F.3
Rowshanrad, A.4
Orozco, L.D.5
Gong, K.W.6
Wang, X.7
Castellani, L.W.8
Reue, K.9
Lusis, A.J.10
Araujo, J.A.11
-
29
-
-
79959732295
-
Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis
-
Freigang, S., Ampenberger, F., Spohn, G., Heer, S., Shamshiev, A. T., Kisielow, J., Hersberger, M., Yamamoto, M., Bachmann, M. F., and Kopf, M. (2011) Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis. Eur. J. Immunol. 41, 2040-2051
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 2040-2051
-
-
Freigang, S.1
Ampenberger, F.2
Spohn, G.3
Heer, S.4
Shamshiev, A.T.5
Kisielow, J.6
Hersberger, M.7
Yamamoto, M.8
Bachmann, M.F.9
Kopf, M.10
-
30
-
-
77950553993
-
Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity
-
Pi, J., Leung, L., Xue, P., Wang, W., Hou, Y., Liu, D., Yehuda-Shnaidman, E., Lee, C., Lau, J., Kurtz, T. W., and Chan, J. Y. (2010) Deficiency in the nuclear factor E2-related factor-2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J. Biol. Chem. 285, 9292-9300
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9292-9300
-
-
Pi, J.1
Leung, L.2
Xue, P.3
Wang, W.4
Hou, Y.5
Liu, D.6
Yehuda-Shnaidman, E.7
Lee, C.8
Lau, J.9
Kurtz, T.W.10
Chan, J.Y.11
-
31
-
-
80053389113
-
Nrf2 represses FGF21 during long-term high-fat diet-induced obesity in mice
-
Chartoumpekis, D. V., Ziros, P. G., Psyrogiannis, A. I., Papavassiliou, A. G., Kyriazopoulou, V. E., Sykiotis, G. P., and Habeos, I. G. (2011) Nrf2 represses FGF21 during long-term high-fat diet-induced obesity in mice. Diabetes 60, 2465-2473
-
(2011)
Diabetes
, vol.60
, pp. 2465-2473
-
-
Chartoumpekis, D.V.1
Ziros, P.G.2
Psyrogiannis, A.I.3
Papavassiliou, A.G.4
Kyriazopoulou, V.E.5
Sykiotis, G.P.6
Habeos, I.G.7
-
32
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell, P., Kono, H., Rayner, K. J., Sirois, C. M., Vladimer, G., Bauernfeind, F. G., Abela, G. S., Franchi, L., Nuñez, G., Schnurr, M., Espevik, T., Lien, E., Fitzgerald, K. A., Rock, K. L., Moore, K. J., Wright, S. D., Hornung, V., and Latz, E. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464, 1357-1361
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nuñez, G.9
Schnurr, M.10
Espevik, T.11
Lien, E.12
Fitzgerald, K.A.13
Rock, K.L.14
Moore, K.J.15
Wright, S.D.16
Hornung, V.17
Latz, E.18
-
33
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
-
Masters, S. L., Dunne, A., Subramanian, S. L., Hull, R. L., Tannahill, G. M., Sharp, F. A., Becker, C., Franchi, L., Yoshihara, E., Chen, Z., Mullooly, N., Mielke, L. A., Harris, J., Coll, R. C., Mills, K. H., Mok, K. H., Newsholme, P., Nuñez, G., Yodoi, J., Kahn, S. E., Lavelle, E. C., and O'Neill, L. A. (2010) Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes. Nat. Immunol. 11, 897-904
-
(2010)
Nat. Immunol.
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
Franchi, L.8
Yoshihara, E.9
Chen, Z.10
Mullooly, N.11
Mielke, L.A.12
Harris, J.13
Coll, R.C.14
Mills, K.H.15
Mok, K.H.16
Newsholme, P.17
Nuñez, G.18
Yodoi, J.19
Kahn, S.E.20
Lavelle, E.C.21
O'Neill, L.A.22
more..
-
34
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar, B., Youm, Y. H., Ravussin, A., Galgani, J. E., Stadler, K., Mynatt, R. L., Ravussin, E., Stephens, J. M., and Dixit, V. D. (2011) The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat. Med. 17, 179-188
-
(2011)
Nat. Med.
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
35
-
-
80053087484
-
Inflammasome is a central player in the induction of obesity and insulin resistance
-
Stienstra, R., van Diepen, J. A., Tack, C. J., Zaki, M. H., van de Veerdonk, F. L., Perera, D., Neale, G. A., Hooiveld, G. J., Hijmans, A., Vroegrijk, I., van den Berg, S., Romijn, J., Rensen, P. C., Joosten, L. A., Netea, M. G., and Kanneganti, T. D. (2011) Inflammasome is a central player in the induction of obesity and insulin resistance. Proc. Natl. Acad. Sci. U.S.A. 108, 15324-15329
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 15324-15329
-
-
Stienstra, R.1
Van Diepen, J.A.2
Tack, C.J.3
Zaki, M.H.4
Van De Veerdonk, F.L.5
Perera, D.6
Neale, G.A.7
Hooiveld, G.J.8
Hijmans, A.9
Vroegrijk, I.10
Van Den Berg, S.11
Romijn, J.12
Rensen, P.C.13
Joosten, L.A.14
Netea, M.G.15
Kanneganti, T.D.16
-
36
-
-
78649498271
-
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
-
Stienstra, R., Joosten, L. A., Koenen, T., van Tits, B., van Diepen, J. A., van den Berg, S. A., Rensen, P. C., Voshol, P. J., Fantuzzi, G., Hijmans, A., Kersten, S., Müller, M., van den Berg, W. B., van Rooijen, N., Wabitsch, M., Kullberg, B. J., van der Meer, J. W., Kanneganti, T., Tack, C. J., and Netea, M. G. (2010) The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab. 12, 593-605
-
(2010)
Cell Metab.
, vol.12
, pp. 593-605
-
-
Stienstra, R.1
Joosten, L.A.2
Koenen, T.3
Van Tits, B.4
Van Diepen, J.A.5
Van Den Berg, S.A.6
Rensen, P.C.7
Voshol, P.J.8
Fantuzzi, G.9
Hijmans, A.10
Kersten, S.11
Müller, M.12
Van Den Berg, W.B.13
Van Rooijen, N.14
Wabitsch, M.15
Kullberg, B.J.16
Van Der Meer, J.W.17
Kanneganti, T.18
Tack, C.J.19
Netea, M.G.20
more..
-
37
-
-
33644985564
-
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
-
Sutterwala, F. S., Ogura, Y., Szczepanik, M., Lara-Tejero, M., Lichtenberger, G. S., Grant, E. P., Bertin, J., Coyle, A. J., Galán, J. E., Askenase, P. W., and Flavell, R. A. (2006) Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24, 317-327
-
(2006)
Immunity
, vol.24
, pp. 317-327
-
-
Sutterwala, F.S.1
Ogura, Y.2
Szczepanik, M.3
Lara-Tejero, M.4
Lichtenberger, G.S.5
Grant, E.P.6
Bertin, J.7
Coyle, A.J.8
Galán, J.E.9
Askenase, P.W.10
Flavell, R.A.11
-
38
-
-
3142654767
-
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
-
DOI 10.1038/nature02664
-
Mariathasan, S., Newton, K., Monack, D. M., Vucic, D., French, D. M., Lee, W. P., Roose-Girma, M., Erickson, S., and Dixit, V. M. (2004) Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf. Nature 430, 213-218 (Pubitemid 38902430)
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 213-218
-
-
Mariathasan, S.1
Hewton, K.2
Monack, D.M.3
Vucic, D.4
French, D.M.5
Lee, W.P.6
Roose-Girma, M.7
Erickson, S.8
Dixit, V.M.9
-
39
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
DOI 10.1006/bbrc.1997.6943
-
Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., Yamamoto, M., and Nabeshima, Y. (1997) An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236, 313-322 (Pubitemid 27373291)
-
(1997)
Biochemical and Biophysical Research Communications
, vol.236
, Issue.2
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.-I.12
-
40
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
-
Fernandes-Alnemri, T., Yu, J. W., Juliana, C., Solorzano, L., Kang, S., Wu, J., Datta, P., McCormick, M., Huang, L., McDermott, E., Eisenlohr, L., Landel, C. P., and Alnemri, E. S. (2010) The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nat. Immunol. 11, 385-393
-
(2010)
Nat. Immunol.
, vol.11
, pp. 385-393
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Juliana, C.3
Solorzano, L.4
Kang, S.5
Wu, J.6
Datta, P.7
McCormick, M.8
Huang, L.9
McDermott, E.10
Eisenlohr, L.11
Landel, C.P.12
Alnemri, E.S.13
-
41
-
-
77957237159
-
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
-
Malhotra, D., Portales-Casamar, E., Singh, A., Srivastava, S., Arenillas, D., Happel, C., Shyr, C., Wakabayashi, N., Kensler, T. W., Wasserman, W. W., and Biswal, S. (2010) Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res. 38, 5718-5734
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 5718-5734
-
-
Malhotra, D.1
Portales-Casamar, E.2
Singh, A.3
Srivastava, S.4
Arenillas, D.5
Happel, C.6
Shyr, C.7
Wakabayashi, N.8
Kensler, T.W.9
Wasserman, W.W.10
Biswal, S.11
-
42
-
-
84869076474
-
Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks
-
Hirotsu, Y., Katsuoka, F., Funayama, R., Nagashima, T., Nishida, Y., Nakayama, K., Engel, J. D., and Yamamoto, M. (2012) Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks. Nucleic Acids Res. 40, 10228-10239
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 10228-10239
-
-
Hirotsu, Y.1
Katsuoka, F.2
Funayama, R.3
Nagashima, T.4
Nishida, Y.5
Nakayama, K.6
Engel, J.D.7
Yamamoto, M.8
-
43
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
DOI 10.1038/sj.cdd.4402194, PII 4402194
-
Fernandes-Alnemri, T., Wu, J., Yu, J. W., Datta, P., Miller, B., Jankowski, W., Rosenberg, S., Zhang, J., and Alnemri, E. S. (2007) The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 14, 1590-1604 (Pubitemid 47278845)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.9
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.-W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
Rosenberg, S.7
Zhang, J.8
Alnemri, E.S.9
-
44
-
-
79960542894
-
Cutting edge: Reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
Bauernfeind, F., Bartok, E., Rieger, A., Franchi, L., Núñez, G., and Hornung, V. (2011) Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J. Immunol. 187, 613-617
-
(2011)
J. Immunol.
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Núñez, G.5
Hornung, V.6
-
46
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
DOI 10.1126/science.1156995
-
Dostert, C., Pétrilli, V., Van Bruggen, R., Steele, C., Mossman, B. T., and Tschopp, J. (2008) Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320, 674-677 (Pubitemid 351928351)
-
(2008)
Science
, vol.320
, Issue.5876
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
47
-
-
79951740151
-
Type I interferon inhibits interleukin-1 production and inflammasome activation
-
Guarda, G., Braun, M., Staehli, F., Tardivel, A., Mattmann, C., Förster, I., Farlik, M., Decker, T., Du Pasquier, R. A., Romero, P., and Tschopp, J. (2011) Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 34, 213-223
-
(2011)
Immunity
, vol.34
, pp. 213-223
-
-
Guarda, G.1
Braun, M.2
Staehli, F.3
Tardivel, A.4
Mattmann, C.5
Förster, I.6
Farlik, M.7
Decker, T.8
Du Pasquier, R.A.9
Romero, P.10
Tschopp, J.11
-
48
-
-
75649096002
-
Thi-oredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou, R., Tardivel, A., Thorens, B., Choi, I., and Tschopp, J. (2010) Thi-oredoxin-interacting protein links oxidative stress to inflammasome activation. Nat. Immunol. 11, 136-140
-
(2010)
Nat. Immunol.
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
49
-
-
79955542142
-
Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression
-
Piantadosi, C. A., Withers, C. M., Bartz, R. R., MacGarvey, N. C., Fu, P., Sweeney, T. E., Welty-Wolf, K. E., and Suliman, H. B. (2011) Heme oxygenase-1 couples activation of mitochondrial biogenesis to anti-inflammatory cytokine expression. J. Biol. Chem. 286, 16374-16385
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 16374-16385
-
-
Piantadosi, C.A.1
Withers, C.M.2
Bartz, R.R.3
MacGarvey, N.C.4
Fu, P.5
Sweeney, T.E.6
Welty-Wolf, K.E.7
Suliman, H.B.8
-
50
-
-
47849120473
-
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
-
Meissner, F., Molawi, K., and Zychlinsky, A. (2008) Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. Nat. Immunol. 9, 866-872
-
(2008)
Nat. Immunol.
, vol.9
, pp. 866-872
-
-
Meissner, F.1
Molawi, K.2
Zychlinsky, A.3
|