-
1
-
-
84867740805
-
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
-
This ImmGen consortia study shows that tissue macrophages have a distinct transcriptional profile that depends on the tissue in which they reside, highlighting the potential contribution of tissue imprinting to macrophage identity.
-
Gautier, E. L. et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat. Immunol. 13, 1118-1128 (2012). This ImmGen consortia study shows that tissue macrophages have a distinct transcriptional profile that depends on the tissue in which they reside, highlighting the potential contribution of tissue imprinting to macrophage identity.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 1118-1128
-
-
Gautier, E.L.1
-
2
-
-
84908322844
-
Diversification of TAM receptor tyrosine kinase function
-
Zagorska, A., Traves, P. G., Lew, E. D., Dransfield, I. & Lemke, G. Diversification of TAM receptor tyrosine kinase function. Nat. Immunol. 15, 920-928 (2014).
-
(2014)
Nat. Immunol.
, vol.15
, pp. 920-928
-
-
Zagorska, A.1
Traves, P.G.2
Lew, E.D.3
Dransfield, I.4
Lemke, G.5
-
3
-
-
84883158032
-
Scavenger receptors in homeostasis and immunity
-
Canton, J., Neculai, D. & Grinstein, S. Scavenger receptors in homeostasis and immunity. Nat. Rev. Immunol. 13, 621-634 (2013).
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 621-634
-
-
Canton, J.1
Neculai, D.2
Grinstein, S.3
-
4
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
-
Kawai, T. & Akira, S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11, 373-384 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
5
-
-
84893652705
-
Alveolar macrophages: Plasticity in a tissue-specific context
-
Hussell, T. & Bell, T. J. Alveolar macrophages: plasticity in a tissue-specific context. Nat. Rev. Immunol. 14, 81-93 (2014).
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 81-93
-
-
Hussell, T.1
Bell, T.J.2
-
6
-
-
58249104981
-
Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis
-
This Study Reveals the Contribution of Tissue-derived Factors in Establishing Macrophage Functional Identity.
-
Kohyama, M. et al. Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis. Nature 457, 318-321 (2009). This study reveals the contribution of tissue-derived factors in establishing macrophage functional identity.
-
(2009)
Nature
, vol.457
, pp. 318-321
-
-
Kohyama, M.1
-
7
-
-
84901358607
-
Monocytes and macrophages: Developmental pathways and tissue homeostasis
-
Ginhoux, F. & Jung, S. Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat. Rev. Immunol. 14, 392-404 (2014).
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 392-404
-
-
Ginhoux, F.1
Jung, S.2
-
8
-
-
84920724791
-
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
-
Lavin, Y. et al. Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell 159, 1312-1326 (2014).
-
(2014)
Cell
, vol.159
, pp. 1312-1326
-
-
Lavin, Y.1
-
9
-
-
0014325451
-
The origin and kinetics of mononuclear phagocytes
-
van Furth, R. & Cohn, Z. A. The origin and kinetics of mononuclear phagocytes. J. Exp. Med. 128, 415-435 (1968).
-
(1968)
J. Exp. Med.
, vol.128
, pp. 415-435
-
-
Van Furth, R.1
Cohn, Z.A.2
-
10
-
-
0036906526
-
Langerhans cells renew in the skin throughout life under steady-state conditions
-
This is the first study that shows that adult mononuclear phagocytes of the epidermis are renewed locally and independently of circulating monocytes.
-
Merad, M. et al. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat. Immunol. 3, 1135-1141 (2002). This is the first study that shows that adult mononuclear phagocytes of the epidermis are renewed locally and independently of circulating monocytes.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1135-1141
-
-
Merad, M.1
-
11
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
This report describes the first fate mapping model that shows that YS-derived cells can contribute to adult microglia.
-
Ginhoux, F. et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330, 841-845 (2010). This report describes the first fate mapping model that shows that YS-derived cells can contribute to adult microglia.
-
(2010)
Science
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
-
12
-
-
36448994709
-
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
-
Ajami, B., Bennett, J. L., Krieger, C., Tetzlaff, W. & Rossi, F. M. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat. Neurosci. 10, 1538-1543 (2007).
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 1538-1543
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
Tetzlaff, W.4
Rossi, F.M.5
-
13
-
-
84876775203
-
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
-
Hashimoto, D. et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 38, 792-804 (2013).
-
(2013)
Immunity
, vol.38
, pp. 792-804
-
-
Hashimoto, D.1
-
14
-
-
84872765982
-
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
-
Yona, S. et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 38, 79-91 (2013).
-
(2013)
Immunity
, vol.38
, pp. 79-91
-
-
Yona, S.1
-
15
-
-
84892450644
-
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation
-
Epelman, S. et al. Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. Immunity 40, 91-104 (2014).
-
(2014)
Immunity
, vol.40
, pp. 91-104
-
-
Epelman, S.1
-
16
-
-
84885454468
-
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
-
This study establishes that fetal monocytes differentiate into alveolar macrophages in response to local CFS2.
-
Guilliams, M. et al. Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF. J. Exp. Med. 210, 1977-1992 (2013). This study establishes that fetal monocytes differentiate into alveolar macrophages in response to local CFS2.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 1977-1992
-
-
Guilliams, M.1
-
17
-
-
84884352076
-
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes
-
Jakubzick, C. et al. Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity 39, 599-610 (2013).
-
(2013)
Immunity
, vol.39
, pp. 599-610
-
-
Jakubzick, C.1
-
18
-
-
79951693243
-
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency
-
This study shows that macrophages are present in normal numbers in patients that lack monocytes.
-
Bigley, V. et al. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. J. Exp. Med. 208, 227-234 (2011). This study shows that macrophages are present in normal numbers in patients that lack monocytes.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 227-234
-
-
Bigley, V.1
-
19
-
-
79960219807
-
IRF8 mutations and human dendritic-cell immunodeficiency
-
Hambleton, S. et al. IRF8 mutations and human dendritic-cell immunodeficiency. N. Engl. J. Med. 365, 127-138 (2011).
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 127-138
-
-
Hambleton, S.1
-
20
-
-
10344255626
-
Turnover of epidermal Langerhans cells
-
This elegant study reports that, in a patient that received a hand allograft, grafted epidermal mononuclear phagocytes (also known as Langerhans cells) remain of donor origin for at least 5 years after transplant, which suggests that, similar to findings in mice, Langerhans cells can renew locally and independently of circulating precursors.
-
Kanitakis, J., Petruzzo, P. & Dubernard, J. M. Turnover of epidermal Langerhans cells. N. Engl. J. Med. 351, 2661-2662 (2004). This elegant study reports that, in a patient that received a hand allograft, grafted epidermal mononuclear phagocytes (also known as Langerhans cells) remain of donor origin for at least 5 years after transplant, which suggests that, similar to findings in mice, Langerhans cells can renew locally and independently of circulating precursors.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2661-2662
-
-
Kanitakis, J.1
Petruzzo, P.2
Dubernard, J.M.3
-
21
-
-
31344469849
-
The fate of human Langerhans cells in hematopoietic stem cell transplantation
-
Collin, M. P. et al. The fate of human Langerhans cells in hematopoietic stem cell transplantation. J. Exp. Med. 203, 27-33 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 27-33
-
-
Collin, M.P.1
-
22
-
-
84907598045
-
Langerhans cell homeostasis and turnover after nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation
-
Mielcarek, M. et al. Langerhans cell homeostasis and turnover after nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation. Transplantation 98, 563-568 (2014).
-
(2014)
Transplantation
, vol.98
, pp. 563-568
-
-
Mielcarek, M.1
-
23
-
-
0034049748
-
Origins and functions of phagocytes in the embryo
-
Lichanska, A. M. & Hume, D. A. Origins and functions of phagocytes in the embryo. Exp. Hematol. 28, 601-611 (2000).
-
(2000)
Exp. Hematol.
, vol.28
, pp. 601-611
-
-
Lichanska, A.M.1
Hume, D.A.2
-
24
-
-
0029996102
-
Development, differentiation, and phenotypic heterogeneity of murine tissue macrophages
-
Naito, M. et al. Development, differentiation, and phenotypic heterogeneity of murine tissue macrophages. J. Leukoc. Biol. 59, 133-138 (1996).
-
(1996)
J. Leukoc. Biol.
, vol.59
, pp. 133-138
-
-
Naito, M.1
-
25
-
-
0024533561
-
Differentiation maturation, and proliferation of macrophages in the mouse yolk sac: A light-microscopic, enzyme-cytochemical, immunohistochemical, and ultrastructural study
-
This study shows that YS-derived primitive macrophages actively proliferate and colonize the embryonic tissues, where they differentiate into fetal macrophages before the development of monocytes.
-
Takahashi, K., Yamamura, F. & Naito, M. Differentiation, maturation, and proliferation of macrophages in the mouse yolk sac: a light-microscopic, enzyme-cytochemical, immunohistochemical, and ultrastructural study. J. Leukoc. Biol. 45, 87-96 (1989). This study shows that YS-derived primitive macrophages actively proliferate and colonize the embryonic tissues, where they differentiate into fetal macrophages before the development of monocytes.
-
(1989)
J. Leukoc. Biol.
, vol.45
, pp. 87-96
-
-
Takahashi, K.1
Yamamura, F.2
Naito, M.3
-
26
-
-
0025289476
-
Development differentiation, and maturation of macrophages in the fetal mouse liver
-
Naito, M., Takahashi, K. & Nishikawa, S. Development, differentiation, and maturation of macrophages in the fetal mouse liver. J. Leukoc. Biol. 48, 27-37 (1990).
-
(1990)
J. Leukoc. Biol.
, vol.48
, pp. 27-37
-
-
Naito, M.1
Takahashi, K.2
Nishikawa, S.3
-
27
-
-
0035887068
-
Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process
-
This study shows that YS-derived macrophages colonize zebrafish embryos before the onset of blood circulation.
-
Herbomel, P., Thisse, B. & Thisse, C. Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process. Dev. Biol. 238, 274-288 (2001). This study shows that YS-derived macrophages colonize zebrafish embryos before the onset of blood circulation.
-
(2001)
Dev. Biol.
, vol.238
, pp. 274-288
-
-
Herbomel, P.1
Thisse, B.2
Thisse, C.3
-
28
-
-
27644497255
-
Three pathways to mature macrophages in the early mouse yolk sac
-
This study describes the different waves of myelopoiesis in the mouse YS.
-
Bertrand, J. Y. et al. Three pathways to mature macrophages in the early mouse yolk sac. Blood 106, 3004-3011 (2005). This study describes the different waves of myelopoiesis in the mouse YS.
-
(2005)
Blood
, vol.106
, pp. 3004-3011
-
-
Bertrand, J.Y.1
-
29
-
-
0033405452
-
Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
-
This study identifies YS-derived cells with erythroid and myeloid potential.
-
Palis, J., Robertson, S., Kennedy, M., Wall, C. & Keller, G. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development 126, 5073-5084 (1999). This study identifies YS-derived cells with erythroid and myeloid potential.
-
(1999)
Development
, vol.126
, pp. 5073-5084
-
-
Palis, J.1
Robertson, S.2
Kennedy, M.3
Wall, C.4
Keller, G.5
-
30
-
-
21444446678
-
Embryonic development of the human hematopoietic system
-
Tavian, M. & Péault, B. Embryonic development of the human hematopoietic system. Int. J. Dev. Biol. 49, 243-250 (2005).
-
(2005)
Int. J. Dev. Biol.
, vol.49
, pp. 243-250
-
-
Tavian, M.1
Péault, B.2
-
31
-
-
0037370698
-
Circulation is established in a stepwise pattern in the mammalian embryo
-
McGrath, K. E., Koniski, A. D., Malik, J. & Palis, J. Circulation is established in a stepwise pattern in the mammalian embryo. Blood 101, 1669-1676 (2003).
-
(2003)
Blood
, vol.101
, pp. 1669-1676
-
-
McGrath, K.E.1
Koniski, A.D.2
Malik, J.3
Palis, J.4
-
32
-
-
0034909083
-
Yolk-sac hematopoiesis: The first blood cells of mouse and man
-
Palis, J. & Yoder, M. C. Yolk-sac hematopoiesis: the first blood cells of mouse and man. Exp. Hematol. 29, 927-936 (2001)
-
(2001)
Exp. Hematol.
, vol.29
, pp. 927-936
-
-
Palis, J.1
Yoder, M.C.2
-
33
-
-
0036848557
-
Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): Role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver
-
Kumaravelu, P. et al. Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver. Development 129, 4891-4899 (2002).
-
(2002)
Development
, vol.129
, pp. 4891-4899
-
-
Kumaravelu, P.1
-
34
-
-
39349096526
-
Hematopoiesis: An evolving paradigm for stem cell biology
-
Orkin, S. H. & Zon, L. I. Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132, 631-644 (2008).
-
(2008)
Cell
, vol.132
, pp. 631-644
-
-
Orkin, S.H.1
Zon, L.I.2
-
35
-
-
34247896991
-
Ontogeny of the hematopoietic system
-
Cumano, A. & Godin, I. Ontogeny of the hematopoietic system. Annu. Rev. Immunol. 25, 745-785 (2007).
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 745-785
-
-
Cumano, A.1
Godin, I.2
-
36
-
-
34247601504
-
Cell tracing shows the contribution of the yolk sac to adult haematopoiesis
-
This is the first fate mapping model to trace the progeny of YS-derived cells.
-
Samokhvalov, I. M., Samokhvalova, N. I. & Nishikawa, S. Cell tracing shows the contribution of the yolk sac to adult haematopoiesis. Nature 446, 1056-1061 (2007). This is the first fate mapping model to trace the progeny of YS-derived cells.
-
(2007)
Nature
, vol.446
, pp. 1056-1061
-
-
Samokhvalov, I.M.1
Samokhvalova, N.I.2
Nishikawa, S.3
-
37
-
-
84864298329
-
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages
-
Hoeffel, G. et al. Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J. Exp. Med. 209, 1167-1181 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1167-1181
-
-
Hoeffel, G.1
-
38
-
-
84928189502
-
C-myb+ erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages
-
This study reveals the contribution of the distinct YS haematopoiesis waves to microglia versus other tissue-resident macrophages.
-
Hoeffel, G. et al. C-myb+ erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages. Immunity 42, 665-678 (2015). This study reveals the contribution of the distinct YS haematopoiesis waves to microglia versus other tissue-resident macrophages.
-
(2015)
Immunity
, vol.42
, pp. 665-678
-
-
Hoeffel, G.1
-
39
-
-
84908148912
-
Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
-
Schneider, C. et al. Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages. Nat. Immunol. 15, 1026-1037 (2014).
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1026-1037
-
-
Schneider, C.1
-
40
-
-
84859508307
-
A lineage of myeloid cells independent of Myb and hematopoietic stem cells
-
This study shows that MYB-deficient mice retain fetal F4/80hi macrophages.
-
Schulz, C. et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 336, 86-90 (2012). This study shows that MYB-deficient mice retain fetal F4/80hi macrophages.
-
(2012)
Science
, vol.336
, pp. 86-90
-
-
Schulz, C.1
-
41
-
-
84925465211
-
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
-
Gomez Perdiguero, E. et al. Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature 518, 547-551 (2015).
-
(2015)
Nature
, vol.518
, pp. 547-551
-
-
Gomez Perdiguero, E.1
-
42
-
-
84933677570
-
Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo
-
McGrath, K. E. et al. Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo. Cell Rep. 11, 1892-1904 (2015).
-
(2015)
Cell Rep.
, vol.11
, pp. 1892-1904
-
-
McGrath, K.E.1
-
43
-
-
38349043771
-
Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo
-
Bertrand, J. Y. et al. Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development 134, 4147-4156 (2007).
-
(2007)
Development
, vol.134
, pp. 4147-4156
-
-
Bertrand, J.Y.1
-
44
-
-
79958715229
-
Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation
-
This study indicates that, upon helminth infection, the T helper 2-type cytokine IL-4 drives the expansion of pleural tissue-resident macrophages without any contribution from monocyte-derived macrophages.
-
Jenkins, S. J. et al. Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science 332, 1284-1288 (2011). This study indicates that, upon helminth infection, the T helper 2-type cytokine IL-4 drives the expansion of pleural tissue-resident macrophages without any contribution from monocyte-derived macrophages.
-
(2011)
Science
, vol.332
, pp. 1284-1288
-
-
Jenkins, S.J.1
-
45
-
-
77249144840
-
Two physically, functionally, and developmentally distinct peritoneal macrophage subsets
-
Ghosn, E. E. et al. Two physically, functionally, and developmentally distinct peritoneal macrophage subsets. Proc. Natl Acad. Sci. USA 107, 2568-2573 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 2568-2573
-
-
Ghosn, E.E.1
-
46
-
-
84886816349
-
IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1
-
Jenkins, S. J. et al. IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1. J. Exp. Med. 210, 2477-2491 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2477-2491
-
-
Jenkins, S.J.1
-
47
-
-
80052246111
-
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
-
This study shows that monocyte-derived macrophages infiltrate, but do not engraft long term in, the inflamed brain.
-
Ajami, B., Bennett, J. L., Krieger, C., McNagny, K. M. & Rossi, F. M. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat. Neurosci. 14, 1142-1149 (2011). This study shows that monocyte-derived macrophages infiltrate, but do not engraft long term in, the inflamed brain.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1142-1149
-
-
Ajami, B.1
Bennett, J.L.2
Krieger, C.3
McNagny, K.M.4
Rossi, F.M.5
-
48
-
-
70049098070
-
Origin of the lamina propria dendritic cell network
-
Bogunovic, M. et al. Origin of the lamina propria dendritic cell network. Immunity 31, 513-525 (2009).
-
(2009)
Immunity
, vol.31
, pp. 513-525
-
-
Bogunovic, M.1
-
49
-
-
70049099836
-
Intestinal lamina propria dendritic cell subsets have different origin and functions
-
Varol, C. et al. Intestinal lamina propria dendritic cell subsets have different origin and functions. Immunity 31, 502-512 (2009).
-
(2009)
Immunity
, vol.31
, pp. 502-512
-
-
Varol, C.1
-
50
-
-
84887616366
-
Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin
-
Tamoutounour, S. et al. Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin. Immunity 39, 925-938 (2013).
-
(2013)
Immunity
, vol.39
, pp. 925-938
-
-
Tamoutounour, S.1
-
51
-
-
84908227801
-
Progressive replacement of embryo-derived cardiac macrophages with age
-
Molawi, K. et al. Progressive replacement of embryo-derived cardiac macrophages with age. J. Exp. Med. 211, 2151-2158 (2014).
-
(2014)
J. Exp. Med.
, vol.211
, pp. 2151-2158
-
-
Molawi, K.1
-
52
-
-
84869229157
-
Two distinct types of Langerhans cells populate the skin during steady state and inflammation
-
Sere, K. et al. Two distinct types of Langerhans cells populate the skin during steady state and inflammation. Immunity 37, 905-916 (2012).
-
(2012)
Immunity
, vol.37
, pp. 905-916
-
-
Sere, K.1
-
53
-
-
84864124259
-
Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin
-
Nagao, K. et al. Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin. Nat. Immunol. 13, 744-752 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 744-752
-
-
Nagao, K.1
-
54
-
-
84921284050
-
Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection
-
Blériot, C. et al. Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection. Immunity 42, 145-158 (2015).
-
(2015)
Immunity
, vol.42
, pp. 145-158
-
-
Blériot, C.1
-
55
-
-
84903625203
-
Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury
-
Zigmond, E. et al. Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury. J. Immunol. 193, 344-353 (2014).
-
(2014)
J. Immunol.
, vol.193
, pp. 344-353
-
-
Zigmond, E.1
-
56
-
-
84909594606
-
Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart
-
Lavine, K. J. et al. Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart. Proc. Natl Acad. Sci. USA 111, 16029-16034 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 16029-16034
-
-
Lavine, K.J.1
-
57
-
-
84865418665
-
Deciphering the transcriptional network of the dendritic cell lineage
-
Miller, J. C. et al. Deciphering the transcriptional network of the dendritic cell lineage. Nat. Immunol. 13, 888-899 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 888-899
-
-
Miller, J.C.1
-
58
-
-
84905989433
-
The role of chromatin dynamics in immune cell development
-
Winter, D. R. & Amit, I. The role of chromatin dynamics in immune cell development. Immunol. Rev. 261, 9-22 (2014).
-
(2014)
Immunol. Rev.
, vol.261
, pp. 9-22
-
-
Winter, D.R.1
Amit, I.2
-
59
-
-
84907419194
-
Immunogenetics. Chromatin state dynamics during blood formation
-
Lara-Astiaso, D. et al. Immunogenetics. Chromatin state dynamics during blood formation. Science 345, 943-949 (2014).
-
(2014)
Science
, vol.345
, pp. 943-949
-
-
Lara-Astiaso, D.1
-
60
-
-
0023899769
-
Nuclease hypersensitive sites in chromatin
-
Gross, D. S. & Garrard, W. T. Nuclease hypersensitive sites in chromatin. Annu. Rev. Biochem. 57, 159-197 (1988).
-
(1988)
Annu. Rev. Biochem.
, vol.57
, pp. 159-197
-
-
Gross, D.S.1
Garrard, W.T.2
-
61
-
-
84866303839
-
A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals
-
Garber, M. et al. A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Mol. Cell 47, 810-822 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 810-822
-
-
Garber, M.1
-
62
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti, S. et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32, 317-328 (2010).
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
-
63
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz, S. et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589 (2010).
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
-
64
-
-
84920724792
-
Environment drives selection and function of enhancers controlling tissue-specific macrophage identities
-
Gosselin, D. et al. Environment drives selection and function of enhancers controlling tissue-specific macrophage identities. Cell 159, 1327-1340 (2014).
-
(2014)
Cell
, vol.159
, pp. 1327-1340
-
-
Gosselin, D.1
-
65
-
-
84886076123
-
Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages
-
Cain, D. W. et al. Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages. J. Immunol. 191, 4665-4675 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 4665-4675
-
-
Cain, D.W.1
-
66
-
-
70449393651
-
MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages
-
Aziz, A., Soucie, E., Sarrazin, S. & Sieweke, M. H. MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages. Science 326, 867-871 (2009).
-
(2009)
Science
, vol.326
, pp. 867-871
-
-
Aziz, A.1
Soucie, E.2
Sarrazin, S.3
Sieweke, M.H.4
-
67
-
-
0034595223
-
MafB is an inducer of monocytic differentiation
-
Kelly, L. M., Englmeier, U., Lafon, I., Sieweke, M. H. & Graf, T. MafB is an inducer of monocytic differentiation. EMBO J. 19, 1987-1997 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 1987-1997
-
-
Kelly, L.M.1
Englmeier, U.2
Lafon, I.3
Sieweke, M.H.4
Graf, T.5
-
68
-
-
84900413094
-
Tissue-specific signals control reversible program of localization and functional polarization of macrophages
-
Okabe, Y. & Medzhitov, R. Tissue-specific signals control reversible program of localization and functional polarization of macrophages. Cell 157, 832-844 (2014).
-
(2014)
Cell
, vol.157
, pp. 832-844
-
-
Okabe, Y.1
Medzhitov, R.2
-
69
-
-
84896366680
-
Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages
-
Haldar, M. et al. Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages. Cell 156, 1223-1234 (2014).
-
(2014)
Cell
, vol.156
, pp. 1223-1234
-
-
Haldar, M.1
-
70
-
-
84883181808
-
Sterols and oxysterols in immune cell function
-
Spann, N. J. & Glass, C. K. Sterols and oxysterols in immune cell function. Nat. Immunol. 14, 893-900 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 893-900
-
-
Spann, N.J.1
Glass, C.K.2
-
71
-
-
0028290252
-
Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse
-
Cecchini, M. G. et al. Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development 120, 1357-1372 (1994).
-
(1994)
Development
, vol.120
, pp. 1357-1372
-
-
Cecchini, M.G.1
-
72
-
-
0035412388
-
Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1op/Csf1op) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis
-
Ryan, G. R. et al. Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1op/Csf1op) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis. Blood 98, 74-84 (2001).
-
(2001)
Blood
, vol.98
, pp. 74-84
-
-
Ryan, G.R.1
-
73
-
-
1642541143
-
Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1-deficient Csf1op/Csf1op mice by transgenic expression of cell surface CSF-1
-
Dai, X. M., Zong, X. H., Sylvestre, V. & Stanley, E. R. Incomplete restoration of colony-stimulating factor 1 (CSF-1) function in CSF-1-deficient Csf1op/Csf1op mice by transgenic expression of cell surface CSF-1. Blood 103, 1114-1123 (2004).
-
(2004)
Blood
, vol.103
, pp. 1114-1123
-
-
Dai, X.M.1
Zong, X.H.2
Sylvestre, V.3
Stanley, E.R.4
-
74
-
-
33645953640
-
Langerhans cells arise from monocytes in vivo
-
Ginhoux, F. et al. Langerhans cells arise from monocytes in vivo. Nat. Immunol. 7, 265-273 (2006).
-
(2006)
Nat. Immunol.
, vol.7
, pp. 265-273
-
-
Ginhoux, F.1
-
75
-
-
79956068261
-
Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation
-
Hashimoto, D. et al. Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J. Exp. Med. 208, 1069-1082 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1069-1082
-
-
Hashimoto, D.1
-
76
-
-
78149462163
-
An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation
-
MacDonald, K. P. et al. An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation. Blood 116, 3955-3963 (2010).
-
(2010)
Blood
, vol.116
, pp. 3955-3963
-
-
MacDonald, K.P.1
-
77
-
-
33846408655
-
Monocytes give rise to mucosal, but not splenic, conventional dendritic cells
-
Varol, C. et al. Monocytes give rise to mucosal, but not splenic, conventional dendritic cells. J. Exp. Med. 204, 171-180 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 171-180
-
-
Varol, C.1
-
78
-
-
84904573974
-
Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility
-
This study shows that macrophages promote neuronal control of gut peristalsis.
-
Muller, P. A. et al. Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility. Cell 158, 300-313 (2014). This study shows that macrophages promote neuronal control of gut peristalsis.
-
(2014)
Cell
, vol.158
, pp. 300-313
-
-
Muller, P.A.1
-
79
-
-
84870907320
-
Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia
-
Greter, M. et al. Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia. Immunity 37, 1050-1060 (2012).
-
(2012)
Immunity
, vol.37
, pp. 1050-1060
-
-
Greter, M.1
-
80
-
-
77957115690
-
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells
-
Wei, S. et al. Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J. Leukoc. Biol. 88, 495-505 (2010).
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 495-505
-
-
Wei, S.1
-
81
-
-
44049092407
-
Discovery of a cytokine and its receptor by functional screening of the extracellular proteome
-
This study led to the identification of IL-34 in human blood, a novel cytokine that shares a receptor with CSF1.
-
Lin, H. et al. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science 320, 807-811 (2008). This study led to the identification of IL-34 in human blood, a novel cytokine that shares a receptor with CSF1.
-
(2008)
Science
, vol.320
, pp. 807-811
-
-
Lin, H.1
-
82
-
-
84862122306
-
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation
-
Nandi, S. et al. The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation. Dev. Biol. 367, 100-113 (2012).
-
(2012)
Dev. Biol.
, vol.367
, pp. 100-113
-
-
Nandi, S.1
-
83
-
-
84864152036
-
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
-
Wang, Y. et al. IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat. Immunol. 13, 753-760 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 753-760
-
-
Wang, Y.1
-
84
-
-
84893745524
-
Identification of a unique TGF-β- dependent molecular and functional signature in microglia
-
Butovsky, O. et al. Identification of a unique TGF-β- dependent molecular and functional signature in microglia. Nat. Neurosci. 17, 131-143 (2014).
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 131-143
-
-
Butovsky, O.1
-
85
-
-
0030456368
-
A role for endogenous transforming growth factor β1 in Langerhans cell biology: The skin of transforming growth factor β1 null mice is devoid of epidermal Langerhans cells
-
Borkowski, T. A., Letterio, J. J., Farr, A. G. & Udey, M. C. A role for endogenous transforming growth factor β1 in Langerhans cell biology: the skin of transforming growth factor β1 null mice is devoid of epidermal Langerhans cells. J. Exp. Med. 184, 2417-2422 (1996).
-
(1996)
J. Exp. Med.
, vol.184
, pp. 2417-2422
-
-
Borkowski, T.A.1
Letterio, J.J.2
Farr, A.G.3
Udey, M.C.4
-
86
-
-
84888348687
-
TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement
-
Bialas, A. R. & Stevens, B. TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement. Nat. Neurosci. 16, 1773-1782 (2013).
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1773-1782
-
-
Bialas, A.R.1
Stevens, B.2
-
87
-
-
84860666662
-
TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment
-
Abutbul, S. et al. TGF-β signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment. Glia 60, 1160-1171 (2012).
-
(2012)
Glia
, vol.60
, pp. 1160-1171
-
-
Abutbul, S.1
-
88
-
-
84862987203
-
Autocrine/paracrine TGF-β1 inhibits Langerhans cell migration
-
Bobr, A. et al. Autocrine/paracrine TGF-β1 inhibits Langerhans cell migration. Proc. Natl Acad. Sci. USA 109, 10492-10497 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 10492-10497
-
-
Bobr, A.1
-
89
-
-
35748948090
-
Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells
-
Kaplan, D. H. et al. Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells. J. Exp. Med. 204, 2545-2552 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2545-2552
-
-
Kaplan, D.H.1
-
90
-
-
84890809254
-
Langerhans cells are generated by two distinct PU. 1-dependent transcriptional networks
-
Chopin, M. et al. Langerhans cells are generated by two distinct PU. 1-dependent transcriptional networks. J. Exp. Med. 210, 2967-2980 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2967-2980
-
-
Chopin, M.1
-
91
-
-
0037386339
-
Transcriptional profiling identifies Id2 function in dendritic cell development
-
Hacker, C. et al. Transcriptional profiling identifies Id2 function in dendritic cell development. Nat. Immunol. 4, 380-386 (2003).
-
(2003)
Nat. Immunol.
, vol.4
, pp. 380-386
-
-
Hacker, C.1
-
92
-
-
80053156515
-
Dendritic cell and macrophage heterogeneity in vivo
-
Hashimoto, D., Miller, J. & Merad, M. Dendritic cell and macrophage heterogeneity in vivo. Immunity 35, 323-335 (2011).
-
(2011)
Immunity
, vol.35
, pp. 323-335
-
-
Hashimoto, D.1
Miller, J.2
Merad, M.3
-
93
-
-
84897053496
-
Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis
-
Mortha, A. et al. Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis. Science 343, 1249288 (2014).
-
(2014)
Science
, vol.343
, pp. 1249288
-
-
Mortha, A.1
-
94
-
-
84901379724
-
Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection
-
Schneider, C. et al. Alveolar macrophages are essential for protection from respiratory failure and associated morbidity following influenza virus infection. PLoS Pathog. 10, e1004053 (2014).
-
(2014)
PLoS Pathog.
, vol.10
, pp. e1004053
-
-
Schneider, C.1
-
95
-
-
38849170507
-
Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis
-
Sainathan, S. K. et al. Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis. Inflamm. Bowel Dis. 14, 88-99 (2008).
-
(2008)
Inflamm. Bowel Dis.
, vol.14
, pp. 88-99
-
-
Sainathan, S.K.1
-
96
-
-
76249096437
-
GM-CSF-facilitated dendritic cell recruitment and survival govern the intestinal mucosal response to a mouse enteric bacterial pathogen
-
Hirata, Y., Egea, L., Dann, S. M., Eckmann, L. & Kagnoff, M. F. GM-CSF-facilitated dendritic cell recruitment and survival govern the intestinal mucosal response to a mouse enteric bacterial pathogen. Cell Host Microbe 7, 151-163 (2010).
-
(2010)
Cell Host Microbe
, vol.7
, pp. 151-163
-
-
Hirata, Y.1
Egea, L.2
Dann, S.M.3
Eckmann, L.4
Kagnoff, M.F.5
-
97
-
-
0026178347
-
Interleukin-1 binds to specific receptors on human bronchial epithelial cells and upregulates granulocyte/macrophage colony-stimulating factor synthesis and release
-
Marini, M., Soloperto, M., Mezzetti, M., Fasoli, A. & Mattoli, S. Interleukin-1 binds to specific receptors on human bronchial epithelial cells and upregulates granulocyte/macrophage colony-stimulating factor synthesis and release. Am. J. Respir. Cell. Mol. Biol. 4, 519-524 (1991).
-
(1991)
Am. J. Respir. Cell. Mol. Biol.
, vol.4
, pp. 519-524
-
-
Marini, M.1
Soloperto, M.2
Mezzetti, M.3
Fasoli, A.4
Mattoli, S.5
-
98
-
-
84873542232
-
GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa
-
Egea, L. et al. GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa. J. Immunol. 190, 1702-1713 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 1702-1713
-
-
Egea, L.1
-
99
-
-
0031718359
-
Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family
-
de Groot, R. P., Coffer, P. J. & Koenderman, L. Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family. Cell. Signal. 10, 619-628 (1998).
-
(1998)
Cell. Signal.
, vol.10
, pp. 619-628
-
-
De Groot, R.P.1
Coffer, P.J.2
Koenderman, L.3
-
100
-
-
84875505809
-
The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells
-
Wan, C. K. et al. The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells. Immunity 38, 514-527 (2013).
-
(2013)
Immunity
, vol.38
, pp. 514-527
-
-
Wan, C.K.1
-
101
-
-
0348230985
-
Peroxisome proliferator-activated receptor-γ is deficient in alveolar macrophages from patients with alveolar proteinosis
-
Bonfield, T. L. et al. Peroxisome proliferator-activated receptor-γ is deficient in alveolar macrophages from patients with alveolar proteinosis. Am. J. Respir. Cell. Mol. Biol. 29, 677-682 (2003).
-
(2003)
Am. J. Respir. Cell. Mol. Biol.
, vol.29
, pp. 677-682
-
-
Bonfield, T.L.1
-
102
-
-
84865410948
-
Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity
-
Gautier, E. L. et al. Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity. J. Immunol. 189, 2614-2624 (2012).
-
(2012)
J. Immunol.
, vol.189
, pp. 2614-2624
-
-
Gautier, E.L.1
-
103
-
-
0347517833
-
Pulmonary alveolar proteinosis
-
Trapnell, B. C., Whitsett, J. A. & Nakata, K. Pulmonary alveolar proteinosis. New Engl. J. Med. 349, 2527-2539 (2003).
-
(2003)
New Engl. J. Med.
, vol.349
, pp. 2527-2539
-
-
Trapnell, B.C.1
Whitsett, J.A.2
Nakata, K.3
-
104
-
-
0028263504
-
Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
-
This report demonstrates that the absence of local production of CSF2 leads to an accumulation of surfactant in the alveolar space of lung tissue.
-
Dranoff, G. et al. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 264, 713-716 (1994). This report demonstrates that the absence of local production of CSF2 leads to an accumulation of surfactant in the alveolar space of lung tissue.
-
(1994)
Science
, vol.264
, pp. 713-716
-
-
Dranoff, G.1
-
105
-
-
84886851330
-
Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function
-
Nakamura, A. et al. Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function. J. Exp. Med. 210, 2191-2204 (2013).
-
(2013)
J. Exp. Med.
, vol.210
, pp. 2191-2204
-
-
Nakamura, A.1
-
106
-
-
12244297799
-
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance
-
Niess, J. H. et al. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307, 254-258 (2005).
-
(2005)
Science
, vol.307
, pp. 254-258
-
-
Niess, J.H.1
-
107
-
-
84893859801
-
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
-
Chang, P. V., Hao, L., Offermanns, S. & Medzhitov, R. The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc. Natl Acad. Sci. USA 111, 2247-2252 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 2247-2252
-
-
Chang, P.V.1
Hao, L.2
Offermanns, S.3
Medzhitov, R.4
-
108
-
-
84900448316
-
Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis
-
Zigmond, E. et al. Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis. Immunity 40, 720-733 (2014).
-
(2014)
Immunity
, vol.40
, pp. 720-733
-
-
Zigmond, E.1
-
109
-
-
84900428511
-
Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function
-
Shouval, D. S. et al. Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function. Immunity 40, 706-719 (2014).
-
(2014)
Immunity
, vol.40
, pp. 706-719
-
-
Shouval, D.S.1
-
110
-
-
33847039159
-
Expression of peroxisome proliferator-activated receptor-γ in macrophage suppresses experimentally induced colitis
-
Shah, Y. M., Morimura, K. & Gonzalez, F. J. Expression of peroxisome proliferator-activated receptor-γ in macrophage suppresses experimentally induced colitis. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G657-G666 (2007).
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
, pp. G657-G666
-
-
Shah, Y.M.1
Morimura, K.2
Gonzalez, F.J.3
-
111
-
-
0031888958
-
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
-
Jiang, C., Ting, A. T. & Seed, B. PPAR-γ agonists inhibit production of monocyte inflammatory cytokines. Nature 391, 82-86 (1998).
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
112
-
-
84870886034
-
Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammation
-
Griseri, T., McKenzie, B. S., Schiering, C. & Powrie, F. Dysregulated hematopoietic stem and progenitor cell activity promotes interleukin-23-driven chronic intestinal inflammation. Immunity 37, 1116-1129 (2012).
-
(2012)
Immunity
, vol.37
, pp. 1116-1129
-
-
Griseri, T.1
McKenzie, B.S.2
Schiering, C.3
Powrie, F.4
-
113
-
-
77952524264
-
Pivotal advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products
-
This study shows that, similar to findings in mice and humans, IL-34 and CSF1 are present and use the same receptor in chickens.
-
Garceau, V. et al. Pivotal advance: avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products. J. Leukoc. Biol. 87, 753-764 (2010). This study shows that, similar to findings in mice and humans, IL-34 and CSF1 are present and use the same receptor in chickens.
-
(2010)
J. Leukoc. Biol.
, vol.87
, pp. 753-764
-
-
Garceau, V.1
-
114
-
-
84878191150
-
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses
-
Schlitzer, A. et al. IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity 38, 970-983 (2013).
-
(2013)
Immunity
, vol.38
, pp. 970-983
-
-
Schlitzer, A.1
-
115
-
-
0036201268
-
GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense
-
Trapnell, B. C. & Whitsett, J. A. GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense. Annu. Rev. Physiol. 64, 775-802 (2002).
-
(2002)
Annu. Rev. Physiol.
, vol.64
, pp. 775-802
-
-
Trapnell, B.C.1
Whitsett, J.A.2
-
116
-
-
72849113090
-
Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice
-
Bedoret, D. et al. Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. J. Clin. Invest. 119, 3723-3738 (2009).
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3723-3738
-
-
Bedoret, D.1
-
117
-
-
84866007988
-
Macrophages and systemic iron homeostasis
-
Ganz, T. Macrophages and systemic iron homeostasis. J. Innate Immun. 4, 446-453 (2012).
-
(2012)
J. Innate Immun.
, vol.4
, pp. 446-453
-
-
Ganz, T.1
-
118
-
-
79251569904
-
Robust erythrophagocytosis leads to macrophage apoptosis via a hemin-mediated redox imbalance: Role in hemolytic disorders
-
Cambos, M. & Scorza, T. Robust erythrophagocytosis leads to macrophage apoptosis via a hemin-mediated redox imbalance: role in hemolytic disorders. J. Leukoc. Biol. 89, 159-171 (2011).
-
(2011)
J. Leukoc. Biol.
, vol.89
, pp. 159-171
-
-
Cambos, M.1
Scorza, T.2
-
119
-
-
84878444005
-
CD169+ macrophages provide a niche promoting erythropoiesis under homeostasis and stress
-
Chow, A. et al. CD169+ macrophages provide a niche promoting erythropoiesis under homeostasis and stress. Nat. Med. 19, 429-436 (2013).
-
(2013)
Nat. Med.
, vol.19
, pp. 429-436
-
-
Chow, A.1
-
120
-
-
84900386841
-
The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal
-
Rosas, M. et al. The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal. Science 344, 645-648 (2014).
-
(2014)
Science
, vol.344
, pp. 645-648
-
-
Rosas, M.1
-
121
-
-
84904407541
-
Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival
-
Gautier, E. L. et al. Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. J. Exp. Med. 211, 1525-1531 (2014).
-
(2014)
J. Exp. Med.
, vol.211
, pp. 1525-1531
-
-
Gautier, E.L.1
-
122
-
-
79951694373
-
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
-
Chow, A. et al. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J. Exp. Med. 208, 261-271 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, pp. 261-271
-
-
Chow, A.1
-
123
-
-
84878299390
-
Rhythmic modulation of the hematopoietic niche through neutrophil clearance
-
Casanova-Acebes, M. et al. Rhythmic modulation of the hematopoietic niche through neutrophil clearance. Cell 153, 1025-1035 (2013).
-
(2013)
Cell
, vol.153
, pp. 1025-1035
-
-
Casanova-Acebes, M.1
-
124
-
-
77955646193
-
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
-
Mendez-Ferrer, S. et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 466, 829-834 (2010).
-
(2010)
Nature
, vol.466
, pp. 829-834
-
-
Mendez-Ferrer, S.1
-
125
-
-
35948935059
-
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells
-
Junt, T. et al. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature 450, 110-114 (2007).
-
(2007)
Nature
, vol.450
, pp. 110-114
-
-
Junt, T.1
-
126
-
-
34447623566
-
B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node
-
Carrasco, Y. R. & Batista, F. D. B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node. Immunity 27, 160-171 (2007).
-
(2007)
Immunity
, vol.27
, pp. 160-171
-
-
Carrasco, Y.R.1
Batista, F.D.2
-
127
-
-
34548044827
-
Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells
-
Phan, T. G., Grigorova, I., Okada, T. & Cyster, J. G. Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells. Nat. Immunol. 8, 992-1000 (2007).
-
(2007)
Nat. Immunol.
, vol.8
, pp. 992-1000
-
-
Phan, T.G.1
Grigorova, I.2
Okada, T.3
Cyster, J.G.4
-
128
-
-
67649221652
-
Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
-
Phan, T. G., Green, J. A., Gray, E. E., Xu, Y. & Cyster, J. G. Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation. Nat. Immunol. 10, 786-793 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 786-793
-
-
Phan, T.G.1
Green, J.A.2
Gray, E.E.3
Xu, Y.4
Cyster, J.G.5
-
129
-
-
84858761664
-
B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity
-
Moseman, E. A. et al. B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity. Immunity 36, 415-426 (2012).
-
(2012)
Immunity
, vol.36
, pp. 415-426
-
-
Moseman, E.A.1
-
130
-
-
77953920853
-
Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus
-
Iannacone, M. et al. Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus. Nature 465, 1079-1083 (2010).
-
(2010)
Nature
, vol.465
, pp. 1079-1083
-
-
Iannacone, M.1
-
131
-
-
84922373441
-
Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection
-
Gaya, M. et al. Host response. Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection. Science 347, 667-672 (2015).
-
(2015)
Science
, vol.347
, pp. 667-672
-
-
Gaya, M.1
-
132
-
-
0042161816
-
Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone
-
Karlsson, M. C. et al. Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone. J. Exp. Med. 198, 333-340 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 333-340
-
-
Karlsson, M.C.1
-
133
-
-
0042847262
-
Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses
-
Aichele, P. et al. Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responses. J. Immunol. 171, 1148-1155 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 1148-1155
-
-
Aichele, P.1
-
134
-
-
84880846105
-
The nuclear receptor LXRα controls the functional specialization of splenic macrophages
-
A.-Gonzalez, N. et al. The nuclear receptor LXRα controls the functional specialization of splenic macrophages. Nat. Immunol. 14, 831-839 (2013).
-
(2013)
Nat. Immunol.
, vol.14
, pp. 831-839
-
-
Gonzalez, N.A.1
-
135
-
-
5444235922
-
LXR-dependent gene expression is important for macrophage survival and the innate immune response
-
Joseph, S. B. et al. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell 119, 299-309 (2004).
-
(2004)
Cell
, vol.119
, pp. 299-309
-
-
Joseph, S.B.1
-
136
-
-
0023876497
-
Iron metabolism in the erythrophagocytosing Kupffer cell
-
Kondo, H., Saito, K., Grasso, J. P. & Aisen, P. Iron metabolism in the erythrophagocytosing Kupffer cell. Hepatology 8, 32-38 (1988).
-
(1988)
Hepatology
, vol.8
, pp. 32-38
-
-
Kondo, H.1
Saito, K.2
Grasso, J.P.3
Aisen, P.4
-
137
-
-
84860997131
-
An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile
-
Pinto, A. R. et al. An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. PLoS ONE 7, e36814 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e36814
-
-
Pinto, A.R.1
-
138
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser, D. M. & Edwards, J. P. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8, 958-969 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
139
-
-
80355146399
-
Transcriptional regulation of macrophage polarization: Enabling diversity with identity
-
Lawrence, T. & Natoli, G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat. Rev. Immunol. 11, 750-761 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 750-761
-
-
Lawrence, T.1
Natoli, G.2
-
140
-
-
0035658031
-
Targeting gene-modified hematopoietic cells to the central nervous system: Use of green fluorescent protein uncovers microglial engraftment
-
Priller, J. et al. Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment. Nat. Med. 7, 1356-1361 (2001).
-
(2001)
Nat. Med.
, vol.7
, pp. 1356-1361
-
-
Priller, J.1
-
141
-
-
37049003544
-
Kupffer cell heterogeneity: Functional properties of bone marrow derived and sessile hepatic macrophages
-
Klein, I. et al. Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages. Blood 110, 4077-4085 (2007).
-
(2007)
Blood
, vol.110
, pp. 4077-4085
-
-
Klein, I.1
-
142
-
-
84920940940
-
Pulmonary macrophage transplantation therapy
-
Suzuki, T. et al. Pulmonary macrophage transplantation therapy. Nature 514, 450-454 (2014).
-
(2014)
Nature
, vol.514
, pp. 450-454
-
-
Suzuki, T.1
-
143
-
-
0015395632
-
The origin of alveolar macrophages in mouse radiation chimeras
-
Godleski, J. J. & Brain, J. D. The origin of alveolar macrophages in mouse radiation chimeras. J. Exp. Med. 136, 630-643 (1972).
-
(1972)
J. Exp. Med.
, vol.136
, pp. 630-643
-
-
Godleski, J.J.1
Brain, J.D.2
-
144
-
-
84907381619
-
Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis
-
Happle, C. et al. Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis. Sci. Transl Med. 6, 250ra113 (2014).
-
(2014)
Sci. Transl Med.
, vol.6
, pp. 250ra113
-
-
Happle, C.1
-
145
-
-
79955750055
-
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic
-
continuum
-
Bendall, S. C. et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 332, 687-696 (2011).
-
(2011)
Science
, vol.332
, pp. 687-696
-
-
Bendall, S.C.1
-
146
-
-
84911016319
-
High-dimensional analysis of the murine myeloid cell system
-
Becher, B. et al. High-dimensional analysis of the murine myeloid cell system. Nat. Immunol. 15, 1181-1189 (2014).
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1181-1189
-
-
Becher, B.1
-
147
-
-
84880280631
-
ViSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia
-
Amir el, A. D. et al. viSNE enables visualization of high dimensional single-cell data and reveals phenotypic heterogeneity of leukemia. Nat. Biotech. 31, 545-552 (2013).
-
(2013)
Nat. Biotech.
, vol.31
, pp. 545-552
-
-
Amir, A.D.1
-
148
-
-
84934442835
-
Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis
-
Levine, J. H. et al. Data-driven phenotypic dissection of AML reveals progenitor-like cells that correlate with prognosis. Cell 162, 184-197 (2015).
-
(2015)
Cell
, vol.162
, pp. 184-197
-
-
Levine, J.H.1
-
149
-
-
84875207585
-
High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states
-
Blecher-Gonen, R. et al. High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states. Nat. Protoc. 8, 539-554 (2013).
-
(2013)
Nat. Protoc.
, vol.8
, pp. 539-554
-
-
Blecher-Gonen, R.1
-
150
-
-
84925546982
-
Epigenetic control of myeloid cell differentiation, identity and function
-
Alvarez-Errico, D., Vento-Tormo, R., Sieweke, M. & Ballestar, E. Epigenetic control of myeloid cell differentiation, identity and function. Nat. Rev. Immunol. 15, 7-17 (2014).
-
(2014)
Nat. Rev. Immunol.
, vol.15
, pp. 7-17
-
-
Alvarez-Errico, D.1
Vento-Tormo, R.2
Sieweke, M.3
Ballestar, E.4
-
151
-
-
84893905629
-
Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types
-
Jaitin, D. A. et al. Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types. Science 343, 776-779 (2014).
-
(2014)
Science
, vol.343
, pp. 776-779
-
-
Jaitin, D.A.1
-
152
-
-
84903185013
-
Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
-
Shalek, A. K. et al. Single-cell RNA-seq reveals dynamic paracrine control of cellular variation. Nature 510, 363-369 (2014).
-
(2014)
Nature
, vol.510
, pp. 363-369
-
-
Shalek, A.K.1
-
153
-
-
84883459000
-
In situ sequencing for RNA analysis in preserved tissue and cells
-
Ke, R. et al. In situ sequencing for RNA analysis in preserved tissue and cells. Nat. Methods 10, 857-860 (2013).
-
(2013)
Nat. Methods
, vol.10
, pp. 857-860
-
-
Ke, R.1
-
154
-
-
84897090228
-
Highly multiplexed subcellular RNA sequencing in situ
-
Lee, J. H. et al. Highly multiplexed subcellular RNA sequencing in situ. Science 343, 1360-1363 (2014).
-
(2014)
Science
, vol.343
, pp. 1360-1363
-
-
Lee, J.H.1
-
155
-
-
84898402897
-
Multiplexed ion beam imaging of human breast tumors
-
Angelo, M. et al. Multiplexed ion beam imaging of human breast tumors. Nat. Med. 20, 436-442 (2014).
-
(2014)
Nat. Med.
, vol.20
, pp. 436-442
-
-
Angelo, M.1
-
156
-
-
84897954497
-
Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry
-
Giesen, C. et al. Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry. Nat. Methods 11, 417-422 (2014).
-
(2014)
Nat. Methods
, vol.11
, pp. 417-422
-
-
Giesen, C.1
-
157
-
-
33344460032
-
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation)
-
Biswas, S. K. et al. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-κB and enhanced IRF-3/STAT1 activation). Blood 107, 2112-2122 (2006).
-
(2006)
Blood
, vol.107
, pp. 2112-2122
-
-
Biswas, S.K.1
-
158
-
-
77955038532
-
Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6Chigh monocytes
-
Movahedi, K. et al. Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6Chigh monocytes. Cancer Res. 70, 5728-5739 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5728-5739
-
-
Movahedi, K.1
-
159
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
Bingle, L., Brown, N. J. & Lewis, C. E. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196, 254-265 (2002).
-
(2002)
J. Pathol.
, vol.196
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
160
-
-
77949345555
-
Tumor-associated macrophages and survival in classic Hodgkins lymphoma
-
Steidl, C. et al. Tumor-associated macrophages and survival in classic Hodgkins lymphoma. N. Engl. J. Med. 362, 875-885 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 875-885
-
-
Steidl, C.1
-
161
-
-
33947432482
-
High macrophage infiltration along the tumor front correlates with improved survival in colon cancer
-
Forssell, J. et al. High macrophage infiltration along the tumor front correlates with improved survival in colon cancer. Clin. Cancer Res. 13, 1472-1479 (2007).
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1472-1479
-
-
Forssell, J.1
-
162
-
-
40849118333
-
High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer
-
Kim, D. W. et al. High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer. Br. J. Cancer 98, 1118-1124 (2008).
-
(2008)
Br. J. Cancer
, vol.98
, pp. 1118-1124
-
-
Kim, D.W.1
-
163
-
-
20444436815
-
Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop
-
This study describes the crosstalk between macrophages and tumour cells that promotes tumour cell invasion.
-
Goswami, S. et al. Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop. Cancer Res. 65, 5278-5283 (2005). This study describes the crosstalk between macrophages and tumour cells that promotes tumour cell invasion.
-
(2005)
Cancer Res.
, vol.65
, pp. 5278-5283
-
-
Goswami, S.1
-
164
-
-
73649122504
-
Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor
-
Patsialou, A. et al. Invasion of human breast cancer cells in vivo requires both paracrine and autocrine loops involving the colony-stimulating factor-1 receptor. Cancer Res. 69, 9498-9506 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 9498-9506
-
-
Patsialou, A.1
-
165
-
-
84875892857
-
Microglia emerge from erythromyeloid precursors via Pu. 1- and Irf8-dependent pathways
-
This study shows that microglia derive from an early wave of YS-derived EMPs.
-
Kierdorf, K. et al. Microglia emerge from erythromyeloid precursors via Pu. 1- and Irf8-dependent pathways. Nat. Neurosci. 16, 273-280 (2013). This study shows that microglia derive from an early wave of YS-derived EMPs.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 273-280
-
-
Kierdorf, K.1
-
166
-
-
84921313153
-
Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
-
Bain, C. C. et al. Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice. Nat. Immunol. 15, 929-937 (2014).
-
(2014)
Nat. Immunol.
, vol.15
, pp. 929-937
-
-
Bain, C.C.1
|