Rapid reprogramming of haemoglobin structure-function exposes multiple dual-antimicrobial potencies

EMBO Journal

Volumn 29, Issue 3, 2010, Pages 632-642

  Du, Ruijuan ^a   Ho, Bow ^b   Ding, Jeak Ling ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Dual antimicrobial activity; Haemoglobin free radicals; Limited proteolysis; Microbe binding and oxidative shock; Reprogramming structure function of haemoglobin

Indexed keywords

ANTIINFECTIVE AGENT; BLOOD SUBSTITUTE; FREE RADICAL; HEMOGLOBIN; PEROXIDASE;

AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG POTENCY; FLOW CYTOMETRY; INVERTEBRATE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROORGANISM; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PSEUDOMONAS AERUGINOSA; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; VIRULENCE;

ADAPTATION, BIOLOGICAL; ANIMALS; ANTI-INFECTIVE AGENTS; BLOOD SUBSTITUTES; HEMOGLOBINS; HORSESHOE CRABS; HUMANS; MICROBIAL SENSITIVITY TESTS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PEROXIDASE; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP;

INVERTEBRATA;

EID: 76349096031     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.380     Document Type: Article

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