-
1
-
-
2342430991
-
Molecular mechanisms of endotoxin tolerance
-
Fan, H. & Cook, J. A. Molecular mechanisms of endotoxin tolerance. J. Endotoxin Res. 10, 71-84 (2004).
-
(2004)
J. Endotoxin Res.
, vol.10
, pp. 71-84
-
-
Fan, H.1
Cook, J.A.2
-
2
-
-
79959558906
-
Endotoxin tolerance represents a distinctive state of alternative polarization (M2) in human mononuclear cells
-
Pena, O. M., Pistolic, J., Raj, D., Fjell, C. D. & Hancock, R. E. Endotoxin tolerance represents a distinctive state of alternative polarization (M2) in human mononuclear cells. J. Immunol. 186, 7243-7254 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 7243-7254
-
-
Pena, O.M.1
Pistolic, J.2
Raj, D.3
Fjell, C.D.4
Hancock, R.E.5
-
3
-
-
79951671510
-
IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
-
Krausgruber, T. et al. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nature Immunol. 12, 231-238 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 231-238
-
-
Krausgruber, T.1
-
4
-
-
84862621234
-
Lipopolysaccharide-activated dendritic cells: ''exhausted'' or alert and waiting?
-
Abdi, K., Singh, N. J. & Matzinger, P. Lipopolysaccharide-activated dendritic cells: ''exhausted'' or alert and waiting? J. Immunol. 188, 5981-5989 (2012).
-
(2012)
J Immunol.
, vol.188
, pp. 5981-5989
-
-
Abdi, K.1
Singh, N.J.2
Matzinger, P.3
-
5
-
-
70349559403
-
Endotoxin tolerance: New mechanisms, molecules and clinical significance
-
Biswas, S. K. & Lopez-Collazo, E. Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol. 30, 475-487 (2009).
-
(2009)
Trends Immunol.
, vol.30
, pp. 475-487
-
-
Biswas, S.K.1
Lopez-Collazo, E.2
-
6
-
-
79959373435
-
Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages
-
Park, S. H., Park-Min, K. H., Chen, J., Hu, X. & Ivashkiv, L. B. Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages. Nature Immunol. 12, 607-615 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 607-615
-
-
Park, S.H.1
Park-Min, K.H.2
Chen, J.3
Hu, X.4
Ivashkiv, L.B.5
-
8
-
-
79952792921
-
Endogenous and exogenous ligands of aryl hydrocarbon receptor: Current state of art
-
Stejskalova, L., Dvorak, Z. & Pavek, P. Endogenous and exogenous ligands of aryl hydrocarbon receptor: current state of art. Curr. Drug Metab. 12, 198-212 (2011).
-
(2011)
Curr. Drug Metab.
, vol.12
, pp. 198-212
-
-
Stejskalova, L.1
Dvorak, Z.2
Pavek, P.3
-
9
-
-
84873318096
-
The aryl hydrocarbon receptor: A molecular pathway for the environmental control of the immune response
-
Quintana, F. J. The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response. Immunology 138, 183-189 (2013).
-
(2013)
Immunology
, vol.138
, pp. 183-189
-
-
Quintana, F.J.1
-
10
-
-
69549126213
-
Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses
-
Kimura, A. et al. Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses. J. Exp. Med. 206, 2027-2035 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2027-2035
-
-
Kimura, A.1
-
11
-
-
38949097735
-
The search for endogenous activators of the aryl hydrocarbon receptor
-
Nguyen, L. P. & Bradfield, C. A. The search for endogenous activators of the aryl hydrocarbon receptor. Chem. Res. Toxicol. 21, 102-116 (2008).
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 102-116
-
-
Nguyen, L.P.1
Bradfield, C.A.2
-
12
-
-
34247267836
-
The human indoleamine 2,3-dioxygenase gene and related human genes
-
Murray, M. F. The human indoleamine 2,3-dioxygenase gene and related human genes. Curr. Drug Metab. 8, 197-200 (2007).
-
(2007)
Curr. Drug Metab.
, vol.8
, pp. 197-200
-
-
Murray, M.F.1
-
13
-
-
33645499663
-
Toward the identification of a tolerogenic signature in IDOcompetent dendritic cells
-
Orabona, C. et al. Toward the identification of a tolerogenic signature in IDOcompetent dendritic cells. Blood 107, 2846-2854 (2006).
-
(2006)
Blood
, vol.107
, pp. 2846-2854
-
-
Orabona, C.1
-
14
-
-
84873412061
-
An expanding range of targets for kynureninemetabolites of tryptophan
-
Stone, T. W., Stoy, N. & Darlington, L. G. An expanding range of targets for kynureninemetabolites of tryptophan. Trends Pharmacol. Sci. 34, 136-143 (2013).
-
(2013)
Trends Pharmacol. Sci.
, vol.34
, pp. 136-143
-
-
Stone, T.W.1
Stoy, N.2
Darlington, L.G.3
-
15
-
-
33646893538
-
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor f-chain and induce a regulatory phenotype in naive T cells
-
Fallarino, F. et al. The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor f-chain and induce a regulatory phenotype in naive T cells. J. Immunol. 176, 6752-6761 (2006).
-
(2006)
J. Immunol.
, vol.176
, pp. 6752-6761
-
-
Fallarino, F.1
-
16
-
-
78650560167
-
Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism
-
Nguyen, N. T. et al. Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism. Proc. Natl Acad. Sci. USA 107, 19961-19966 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 19961-19966
-
-
Nguyen, N.T.1
-
17
-
-
78649880396
-
An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells
-
Mezrich, J. D. et al. An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells. J. Immunol. 185, 3190-3198 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 3190-3198
-
-
Mezrich, J.D.1
-
18
-
-
38049115134
-
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease
-
Romani, L. et al. Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature 451, 211-215 (2008).
-
(2008)
Nature
, vol.451
, pp. 211-215
-
-
Romani, L.1
-
19
-
-
81855221935
-
Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis
-
Changsirivathanathamrong, D. et al. Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis. Crit. Care Med. 39, 2678-2683 (2011).
-
(2011)
Crit. Care Med.
, vol.39
, pp. 2678-2683
-
-
Changsirivathanathamrong, D.1
-
20
-
-
64849108173
-
Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock
-
Jung, I. D. et al. Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock. J. Immunol. 182, 3146-3154 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 3146-3154
-
-
Jung, I.D.1
-
21
-
-
71949098229
-
Hypersensitivity of aryl hydrocarbon receptor-deficient mice to lipopolysaccharide-induced septic shock
-
Sekine, H. et al. Hypersensitivity of aryl hydrocarbon receptor-deficient mice to lipopolysaccharide-induced septic shock. Mol. Cell. Biol. 29, 6391-6400 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 6391-6400
-
-
Sekine, H.1
-
22
-
-
67651171182
-
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17 TH1 and TH2 cells
-
Trifari, S., Kaplan, C. D., Tran, E. H., Crellin, N. K. & Spits, H. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells. Nature Immunol. 10, 864-871 (2009).
-
(2009)
Nature Mmunol.
, vol.10
, pp. 864-871
-
-
Trifari, S.1
Kaplan, C.D.2
Tran, E.H.3
Crellin, N.K.4
Spits, H.5
-
23
-
-
77951738344
-
Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists
-
Howard, G. J., Schlezinger, J. J., Hahn, M. E. & Webster, T. F. Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists. Environ. Health Perspect. 118, 666-672 (2009).
-
(2009)
Environ. Health Perspect.
, vol.118
, pp. 666-672
-
-
Howard, G.J.1
Schlezinger, J.J.2
Hahn, M.E.3
Webster, T.F.4
-
24
-
-
67649612842
-
Detection of the TCDD binding-fingerprint within the Ah receptor ligandbinding domain by structurally drivenmutagenesis and functionalanalysis
-
Pandini, A. et al. Detection of the TCDD binding-fingerprint within the Ah receptor ligandbinding domain by structurally drivenmutagenesis and functionalanalysis. Biochemistry 48, 5972-5983 (2009).
-
(2009)
Biochemistry
, vol.48
, pp. 5972-5983
-
-
Pandini, A.1
-
25
-
-
80054041992
-
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
-
Opitz, C. A. et al. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature 478, 197-203 (2011).
-
(2011)
Nature
, vol.478
, pp. 197-203
-
-
Opitz, C.A.1
-
26
-
-
84864776540
-
Indoleamine 2,3-dioxygenase: From catalyst to signaling function
-
Fallarino, F., Grohmann, U. & Puccetti, P. Indoleamine 2,3-dioxygenase: from catalyst to signaling function. Eur. J. Immunol. 42, 1932-1937 (2012).
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1932-1937
-
-
Fallarino, F.1
Grohmann, U.2
Puccetti, P.3
-
27
-
-
37349076668
-
Functional yet balanced reactivity to Candida albicans requires TRIF MyD88 and IDO-dependent inhibition of Rorc
-
De Luca, A. et al. Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc. J. Immunol. 179, 5999-6008 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 5999-6008
-
-
De Luca, A.1
-
28
-
-
80052020183
-
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
-
Pallotta, M. T. et al. Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nature Immunol. 12, 870-878 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 870-878
-
-
Pallotta, M.T.1
-
29
-
-
79551618199
-
FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor
-
Dong, B. et al. FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor. Biochim. Biophys. Acta 1810, 427-431 (2011).
-
(2011)
Biochim. Biophys. Acta
, vol.1810
, pp. 427-431
-
-
Dong, B.1
-
30
-
-
39949085040
-
Hexachlorobenzene triggers AhR translocation to the nucleus, c-Src activation and EGFR transactivation in rat liver
-
Randi, A. S. et al. Hexachlorobenzene triggers AhR translocation to the nucleus, c-Src activation and EGFR transactivation in rat liver. Toxicol. Lett. 177, 116-122 (2008).
-
(2008)
Toxicol. Lett.
, vol.177
, pp. 116-122
-
-
Randi, A.S.1
-
31
-
-
4644356710
-
Regulation of aryl hydrocarbon receptor signal transduction by protein tyrosine kinases
-
Backlund, M. & Ingelman-Sundberg, M. Regulation of aryl hydrocarbon receptor signal transduction by protein tyrosine kinases. Cell. Signal. 17, 39-48 (2005).
-
(2005)
Cell. Signal.
, vol.17
, pp. 39-48
-
-
Backlund, M.1
Ingelman-Sundberg, M.2
-
32
-
-
80054806900
-
Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota
-
Thiennimitr, P. et al. Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota. Proc. Natl Acad. Sci. USA 108, 17480-17485 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 17480-17485
-
-
Thiennimitr, P.1
-
33
-
-
63149098784
-
Toll-like receptor 2deficiency is associated with enhanced severity of groupBstreptococcal disease
-
Puliti, M., Uematsu, S., Akira, S., Bistoni, F. & Tissi, L. Toll-like receptor 2deficiency is associated with enhanced severity of groupBstreptococcal disease. Infect. Immun. 77, 1524-1531 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 1524-1531
-
-
Puliti, M.1
Uematsu, S.2
Akira, S.3
Bistoni, F.4
Tissi, L.5
-
34
-
-
79952126441
-
Tissue-based class control: The other side of tolerance
-
Matzinger, P. & Kamala, T. Tissue-based class control: the other side of tolerance. Nature Rev. Immunol. 11, 221-230 (2011).
-
(2011)
Nature Rev. Immunol.
, vol.11
, pp. 221-230
-
-
Matzinger, P.1
Kamala, T.2
-
35
-
-
77954399377
-
Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function
-
Sander, L. E. et al. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J. Exp. Med. 207, 1453-1464 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1453-1464
-
-
Sander, L.E.1
-
36
-
-
33645984274
-
Protective tolerance to fungi: The role of IL-10 and tryptophan catabolism
-
Romani, L. & Puccetti, P. Protective tolerance to fungi: the role of IL-10 and tryptophan catabolism. Trends Microbiol. 14, 183-189 (2006).
-
(2006)
Trends Microbiol.
, vol.14
, pp. 183-189
-
-
Romani, L.1
Puccetti, P.2
-
37
-
-
60649100625
-
TGF-b and kynurenines as the key to infectious tolerance
-
Belladonna, M. L., Orabona, C., Grohmann, U. & Puccetti, P. TGF-b and kynurenines as the key to infectious tolerance. Trends Mol. Med. 15, 41-49 (2009).
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 41-49
-
-
Belladonna, M.L.1
Orabona, C.2
Grohmann, U.3
Puccetti, P.4
-
38
-
-
84857538593
-
Disease tolerance as a defense strategy
-
Medzhitov, R., Schneider, D. S. & Soares, M. P. Disease tolerance as a defense strategy. Science 335, 936-941 (2012).
-
(2012)
Science
, vol.335
, pp. 936-941
-
-
Medzhitov, R.1
Schneider, D.S.2
Soares, M.P.3
-
39
-
-
84878707549
-
High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway
-
Volpi, C. et al. High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway. Nature Commun. 4, 1852 (2013).
-
(2013)
Nature Commun.
, vol.4
, pp. 1852
-
-
Volpi, C.1
-
40
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann, U. et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nature Immunol. 3, 1097-1101 (2002).
-
(2002)
Nature Immunol.
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
-
41
-
-
0346119234
-
Modulation of tryptophan catabolismby regulatoryT cells
-
Fallarino, F. et al. Modulation of tryptophan catabolismby regulatoryT cells. Nature Immunol. 4, 1206-1212 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 1206-1212
-
-
Fallarino, F.1
-
42
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn, D. H. et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 281, 1191-1193 (1998).
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
-
43
-
-
84863619688
-
Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict
-
Samstein, R. M., Josefowicz, S. Z., Arvey, A., Treuting, P. M. & Rudensky, A. Y. Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict. Cell 150, 29-38 (2012).
-
(2012)
Cell
, vol.150
, pp. 29-38
-
-
Samstein, R.M.1
Josefowicz, S.Z.2
Arvey, A.3
Treuting, P.M.4
Rudensky, A.Y.5
-
44
-
-
84882664672
-
Tryptophan catabolites frommicrobiota engage aryl hydrocarbon receptor andbalancemucosal reactivity via interleukin-22
-
Zelante, T. et al. Tryptophan catabolites frommicrobiota engage aryl hydrocarbon receptor andbalancemucosal reactivity via interleukin-22. Immunity 39, 372-385 (2013).
-
(2013)
Immunity
, vol.39
, pp. 372-385
-
-
Zelante, T.1
-
45
-
-
58249103970
-
Indoleamine 2,3- dioxygenase in infection: The paradox of an evasive strategy that benefits the host
-
Zelante, T., Fallarino, F., Bistoni, F., Puccetti, P. & Romani, L. Indoleamine 2,3- dioxygenase in infection: the paradox of an evasive strategy that benefits the host. Microbes Infect. 11, 133-141 (2009).
-
(2009)
Microbes Infect.
, vol.11
, pp. 133-141
-
-
Zelante, T.1
Fallarino, F.2
Bistoni, F.3
Puccetti, P.4
Romani, L.5
-
46
-
-
80052016154
-
More than an enzyme
-
Chen, W. IDO: more than an enzyme. Nature Immunol. 12, 809-811 (2011).
-
(2011)
Nature Immunol.
, vol.12
, pp. 809-811
-
-
Chen, W.1
-
47
-
-
66749174867
-
The inflammasomes: Guardians of the body
-
Martinon, F., Mayor, A. & Tschopp, J. The inflammasomes: guardians of the body. Annu. Rev. Immunol. 27, 229-265 (2009).
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 229-265
-
-
Martinon, F.1
Mayor, A.2
Tschopp, J.3
-
48
-
-
84865544578
-
Balancing resistance and infection tolerance through metabolic means
-
Chambers, M. C. & Schneider, D. S. Balancing resistance and infection tolerance through metabolic means. Proc. Natl Acad. Sci. USA 109, 13886-13887 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 13886-13887
-
-
Chambers, M.C.1
Schneider, D.S.2
|