LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling

Cytokine

Volumn 74, Issue 2, 2015, Pages 198-206

  Bruns, Annie M ^a   Horvath, Curt M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Antiviral immunity; LGP2; MDA5; RIG I like receptors

Indexed keywords

ADENOSINE TRIPHOSPHATE; DOUBLE STRANDED RNA; LABORATORY OF GENETICS AND PHYSIOLOGY 2 PROTEIN; PROTEIN MDA5; RETINOIC ACID INDUCIBLE GENE I LIKE RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; RNA; RNA HELICASE; UNCLASSIFIED DRUG; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; DHX58 PROTEIN, HUMAN; IFIH1 PROTEIN, HUMAN; INTERFERON INDUCED HELICASE C DOMAIN CONTAINING PROTEIN 1; VIRUS RNA;

BINDING SITE; CONFORMATIONAL TRANSITION; CYTOPLASM; DISSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE REARRANGEMENT; HUMAN; HYDROLYSIS; MAMMAL CELL; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN STRUCTURE; REVIEW; RNA ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; IMMUNOLOGY;

ANIMALS; DEAD BOX PROTEIN 58; DEAD-BOX RNA HELICASES; HUMANS; INTERFERON-INDUCED HELICASE, IFIH1; RNA HELICASES; RNA, DOUBLE-STRANDED; RNA, VIRAL; SIGNAL TRANSDUCTION;

EID: 84949725975     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2015.02.010     Document Type: Review

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