Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2

Journal of Biological Chemistry

Volumn 284, Issue 15, 2009, Pages 9700-9712

  Bamming, Darja ^a   Horvath, Curt M ^a,b,c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Pancoe ENH Pavilion ^*  (United States)

^c Pancoe ENH Pavilion   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRAL ACTIVITIES; ATP HYDROLYSIS; CATALYTIC ACTIVITY; CELLULAR RESPONSE; ENZYMATIC ACTIVITIES; ESSENTIAL COMPONENT; HELICASE; HELICASE ACTIVITIES; I-MOTIF; INACTIVE MUTANTS; INTERFERON INDUCTION; PATTERN RECOGNITION RECEPTORS; RNA BINDING; RNA HELICASE; SEQUENCE MOTIFS; SIGNALING PROTEINS; TYPE I INTERFERONS; VIRUS INFECTION;

ANTIBIOTICS; BACTERIOPHAGES; GLYCOPROTEINS; HYDROLYSIS; NUCLEIC ACIDS; PATTERN RECOGNITION; PROTEINS; RNA; SIGNALING;

SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; CYTOKINE; INTERFERON; LGP2 HELICASE; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5; PATTERN RECOGNITION RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; RNA; RNA HELICASE; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; DHX58 PROTEIN, HUMAN; IFIH1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; ENZYME ACTIVITY; ENZYME INACTIVATION; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN INDUCTION; PROTEIN MOTIF; RNA BINDING; SIGNAL TRANSDUCTION; VESICULAR STOMATITIS VIRUS; VIRUS INTERFERENCE; VIRUS RESISTANCE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; INSECT; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; SEQUENCE HOMOLOGY;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIVIRAL AGENTS; DEAD-BOX RNA HELICASES; HUMANS; INSECTS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RNA HELICASES; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 65649083024     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807365200     Document Type: Article

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