The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly

Molecular Cell

Volumn 55, Issue 5, 2014, Pages 771-781

  Bruns, AnnieM ^a   Leser, GeorgeP ^a   Lamb, RobertA ^a   Horvath, CurtM ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DOUBLE STRANDED RNA; LGP2 PROTEIN; MDA5 PROTEIN; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; VIRUS RNA; DEAD BOX PROTEIN; DHX58 PROTEIN, HUMAN; IFIH1 PROTEIN, HUMAN; RNA HELICASE;

ARTICLE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IN VIVO STUDY; INNATE IMMUNITY; NONHUMAN; OLIGOMERIZATION; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; SIGNAL TRANSDUCTION; VIRUS ASSEMBLY; CHEMISTRY; HEK293 CELL LINE; HYDROLYSIS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; DEAD-BOX RNA HELICASES; HEK293 CELLS; HUMANS; HYDROLYSIS; IMMUNITY, INNATE; RNA HELICASES; RNA, DOUBLE-STRANDED; RNA, VIRAL; SIGNAL TRANSDUCTION;

EID: 84926104091     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.07.003     Document Type: Article

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