ATP hydrolysis enhances RNA recognition and antiviral signal transduction by the innate immune sensor, laboratory of genetics and physiology 2 (LGP2)

Journal of Biological Chemistry

Volumn 288, Issue 2, 2013, Pages 938-946

  Bruns, Annie M ^a   Pollpeter, Darja ^a   Hadizadeh, Nastaran ^a   Myong, Sua ^b   Marko, John F ^a   Horvath, Curt M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP HYDROLYSIS; ATP-HYDROLYSIS ACTIVITY; BIOCHEMICAL ASSAY; BIOLOGICAL RESPONSE; ENZYMATIC ACTIVITIES; ENZYMATIC PROPERTIES; HYDROLYSIS ACTIVITY; IN-VIVO; MOLECULAR SIGNATURES; PATTERN RECOGNITION RECEPTORS; RNA INTERACTION; RNA RECOGNITION; SINGLE-MOLECULE ANALYSIS; VIRUS INFECTION;

CHROMOSOMES; PATTERN RECOGNITION; PHYSIOLOGY; RNA; SIGNAL TRANSDUCTION; VIRUSES;

HYDROLYSIS;

ADENOSINE TRIPHOSPHATE; BETA INTERFERON; DOUBLE STRANDED RNA; LABORATORY OF GENETICS AND PHYSIOLOGY 2 PROTEIN; MUTANT PROTEIN; PATTERN RECOGNITION RECEPTOR; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN MDA5; PROTEIN VARIANT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; ENCEPHALOMYOCARDITIS VIRUS INFECTION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SUBSTRATE COMPLEX; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; QUANTITATIVE ANALYSIS; RNA ANALYSIS; RNA INTERFERENCE; RNA VIRUS INFECTION; SIGNAL TRANSDUCTION; VIRUS INFECTION; VIRUS INHIBITION;

ADENOSINE TRIPHOSPHATE; ANTIVIRAL AGENTS; BASE SEQUENCE; HEK293 CELLS; HUMANS; HYDROLYSIS; IMMUNITY, INNATE; MUTAGENESIS, SITE-DIRECTED; RNA; RNA HELICASES; SIGNAL TRANSDUCTION;

ENCEPHALOMYOCARDITIS VIRUS;

EID: 84872348735     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.424416     Document Type: Article

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