Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses

Molecular Cell

Volumn 29, Issue 4, 2008, Pages 428-440

  Takahasi, Kiyohiro ^a   Yoneyama, Mitsutoshi ^b,d   Nishihori, Tatsuya ^a   Hirai, Reiko ^b   Kumeta, Hiroyuki ^a   Narita, Ryo ^b   Gale Jr , Michael ^c   Inagaki, Fuyuhiko ^a   Fujita, Takashi ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

MOLIMMUNO; RNA

Indexed keywords

ADENOSINE TRIPHOSPHATE; DOUBLE STRANDED RNA; PROTEINASE; RETINOIC ACID INDUCIBLE PROTEIN I; SINGLE STRANDED RNA; VIRUS RNA;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME METABOLISM; GENE REPRESSION; GENE STRUCTURE; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOSTIMULATION; MOLECULAR RECOGNITION; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RNA BINDING; STRUCTURE ANALYSIS; VIRUS IMMUNITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; DEAD-BOX RNA HELICASES; GENE EXPRESSION REGULATION; HUMANS; IMMUNE SYSTEM; INTERFERON REGULATORY FACTOR-3; INTERFERONS; MICE; MICE, KNOCKOUT; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RNA, DOUBLE-STRANDED; RNA, VIRAL; SEQUENCE ALIGNMENT;

EID: 39649092731     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2007.11.028     Document Type: Article

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