RIG-I-like receptors evolved adaptively in mammals, with parallel evolution at LGP2 and RIG-I

Journal of Molecular Biology

Volumn 426, Issue 6, 2014, Pages 1351-1365

  Cagliani, Rachele ^a   Forni, Diego ^a   Tresoldi, Claudia ^a   Pozzoli, Uberto ^a   Filippi, Giulia ^b   Rainone, Veronica ^c   De Gioia, Luca ^b   Clerici, Mario ^c,d   Sironi, Manuela ^a  

^a SCIENTIFIC INSTITUTE   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

LGP2; MDA5; positive selection; RIG I; RIG I like receptors

Indexed keywords

ANTIVIRUS AGENT; RETINOIC ACID INDUCIBLE PROTEIN I; RIG 1 LIKE RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN V;

ALPHA HELIX; ARTICLE; DIVERSIFYING SELECTION; HUMAN; INNATE IMMUNITY; NONHUMAN; PARAINFLUENZA VIRUS 5; PRIORITY JOURNAL; PURIFYING SELECTION; VIRUS CELL INTERACTION;

MAMMALIA; PARAINFLUENZA VIRUS;

LGP2; MDA5; POSITIVE SELECTION; RIG-I; RIG-I-LIKE RECEPTORS;

ADAPTIVE IMMUNITY; AMINO ACID SEQUENCE; ANIMALS; DEAD-BOX RNA HELICASES; EVOLUTION, MOLECULAR; HOST-PATHOGEN INTERACTIONS; HUMANS; MAMMALS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, PATTERN RECOGNITION; RECEPTORS, RETINOIC ACID; RNA HELICASES; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84896689557     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.10.040     Document Type: Article

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