The Specific and Essential Role of MAVS in Antiviral Innate Immune Responses

Immunity

Volumn 24, Issue 5, 2006, Pages 633-642

  Sun, Qinmiao ^a   Sun, Lijun ^a   Liu, Hong Hsing ^a   Chen, Xiang ^a   Seth, Rashu B ^a   Forman, James ^a   Chen, Zhijian J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

MICROBIO; MOLIMMUNO; SIGNALING

Indexed keywords

DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; MITOCHONDRIAL PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL TYPE; CONTROLLED STUDY; CYTOSOL; DENDRITIC CELL; FERTILITY; FIBROBLAST; IMMUNE RESPONSE; IN VIVO STUDY; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; MACROPHAGE; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; VIRUS INDUCTION; VIRUS INFECTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, SOUTHERN; BLOTTING, WESTERN; FIBROBLASTS; IMMUNITY, NATURAL; INTERFERON REGULATORY FACTOR-3; INTERFERONS; LISTERIA INFECTIONS; MACROPHAGES; MICE; MICE, MUTANT STRAINS; MITOCHONDRIAL PROTEINS; NF-KAPPA B; RHABDOVIRIDAE INFECTIONS; VESICULAR STOMATITIS-INDIANA VIRUS; VIRUS DISEASES;

EID: 33646592188     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2006.04.004     Document Type: Article

References (39)

1. Berg R.E., Crossley E., Murray S., and Forman J. Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen. J. Exp. Med. 198 (2003) 1583-1593
2. Bigger C.B., Guerra B., Brasky K.M., Hubbard G., Beard M.R., Luxon B.A., Lemon S.M., and Lanford R.E. Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzees. J. Virol. 78 (2004) 13779-13792
3. Dalton K.P., and Rose J.K. Vesicular stomatitis virus glycoprotein containing the entire green fluorescent protein on its cytoplasmic domain is incorporated efficiently into virus particles. Virology 279 (2001) 414-421
4. Darnell Jr. J.E., Kerr I.M., and Stark G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264 (1994) 1415-1421
5. Diebold S.S., Kaisho T., Hemmi H., Akira S., and Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303 (2004) 1529-1531
6. Fitzgerald K.A., McWhirter S.M., Faia K.L., Rowe D.C., Latz E., Golenbock D.T., Coyle A.J., Liao S.M., and Maniatis T. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nat. Immunol. 4 (2003) 491-496
7. Freundt E.C., and Lenardo M.J. Interfering with interferons: Hepatitis C virus counters innate immunity. Proc. Natl. Acad. Sci. USA 102 (2005) 17539-17540
8. Heil F., Hemmi H., Hochrein H., Ampenberger F., Kirschning C., Akira S., Lipford G., Wagner H., and Bauer S. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303 (2004) 1526-1529
9. Honda K., Yanai H., Takaoka A., and Taniguchi T. Regulation of the type I IFN induction: a current view. Int. Immunol. 17 (2005) 1367-1378
10. Hornung V., Schlender J., Guenthner-Biller M., Rothenfusser S., Endres S., Conzelmann K.K., and Hartmann G. Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus. J. Immunol. 173 (2004) 5935-5943
11. Ishii K.J., Coban C., Kato H., Takahashi K., Torii Y., Takeshita F., Ludwig H., Sutter G., Suzuki K., Hemmi H., et al. A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat. Immunol. 7 (2006) 40-48
12. Kato H., Sato S., Yoneyama M., Yamamoto M., Uematsu S., Matsui K., Tsujimura T., Takeda K., Fujita T., Takeuchi O., and Akira S. Cell type-specific involvement of RIG-I in antiviral response. Immunity 23 (2005) 19-28
13. Kato H., Takeuchi O., Sato S., Yoneyama M., Yamamoto M., Matsui K., Uematsu S., Jung A., Kawai T., Ishii K.J., et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441 (2006) 101-105
14. Kawai T., and Akira S. Innate immune recognition of viral infection. Nat. Immunol. 7 (2006) 131-137
15. Kawai T., Takahashi K., Sato S., Coban C., Kumar H., Kato H., Ishii K.J., Takeuchi O., and Akira S. IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat. Immunol. 6 (2005) 981-988
16. Lamarre D., Anderson P.C., Bailey M., Beaulieu P., Bolger G., Bonneau P., Bos M., Cameron D.R., Cartier M., Cordingley M.G., et al. An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus. Nature 426 (2003) 186-189
17. Lee J., Wu C.C., Lee K.J., Chuang T.H., Katakura K., Liu Y.T., Chan M., Tawatao R., Chung M., Shen C., et al. Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Proc. Natl. Acad. Sci. USA 103 (2006) 1828-1833
18. Levy D.E. Whence interferon? Variety in the production of interferon in response to viral infection. J. Exp. Med. 195 (2002) F15-F18
19. Li X.D., Sun L., Seth R.B., Pineda G., and Chen Z.J. Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc. Natl. Acad. Sci. USA 102 (2005) 17717-17722
20. Liu Y.J. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106 (2001) 259-262
21. Lund J.M., Alexopoulou L., Sato A., Karow M., Adams N.C., Gale N.W., Iwasaki A., and Flavell R.A. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc. Natl. Acad. Sci. USA 101 (2004) 5598-5603
22. Machida K., Cheng K.T., Sung V.M., Levine A.M., Foung S., and Lai M.M. Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6. J. Virol. 80 (2006) 866-874
23. Maniatis T., Falvo J.V., Kim T.H., Kim T.K., Lin C.H., Parekh B.S., and Wathelet M.G. Structure and function of the interferon-beta enhanceosome. Cold Spring Harb. Symp. Quant. Biol. 63 (1998) 609-620
24. McWhirter S.M., Tenoever B.R., and Maniatis T. Connecting mitochondria and innate immunity. Cell 122 (2005) 645-647
25. Meylan E., Curran J., Hofmann K., Moradpour D., Binder M., Bartenschlager R., and Tschopp J. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437 (2005) 1167-1172
26. O'Connell R.M., Vaidya S.A., Perry A.K., Saha S.K., Dempsey P.W., and Cheng G. Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1. J. Immunol. 174 (2005) 1602-1607
27. O'Neill L.A. Immunology. After the toll rush. Science 303 (2004) 1481-1482
28. Oganesyan G., Saha S.K., Guo B., He J.Q., Shahangian A., Zarnegar B., Perry A., and Cheng G. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 439 (2006) 208-211
29. Okabe Y., Kawane K., Akira S., Taniguchi T., and Nagata S. Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation. J. Exp. Med. 202 (2005) 1333-1339
30. Perry A.K., Chen G., Zheng D., Tang H., and Cheng G. The host type I interferon response to viral and bacterial infections. Cell Res. 15 (2005) 407-422
31. Seth R.B., Sun L., Ea C.K., and Chen Z.J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122 (2005) 669-682
32. Seth R.B., Sun L., and Chen Z.J. Antiviral innate immunity pathways. Cell Res. 16 (2006) 141-147
33. Sharma S., tenOever B.R., Grandvaux N., Zhou G.P., Lin R., and Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science 300 (2003) 1148-1151
34. Silverman N., and Maniatis T. NF-kappaB signaling pathways in mammalian and insect innate immunity. Genes Dev. 15 (2001) 2321-2342
35. Stetson D.B., and Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24 (2006) 93-103
36. Stockinger S., Reutterer B., Schaljo B., Schellack C., Brunner S., Materna T., Yamamoto M., Akira S., Taniguchi T., Murray P.J., et al. IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism. J. Immunol. 173 (2004) 7416-7425
37. Wieland S.F., and Chisari F.V. Stealth and cunning: hepatitis B and hepatitis C viruses. J. Virol. 79 (2005) 9369-9380
38. Xu L.G., Wang Y.Y., Han K.J., Li L.Y., Zhai Z., and Shu H.B. VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol. Cell 19 (2005) 727-740
39. Yoneyama M., Kikuchi M., Natsukawa T., Shinobu N., Imaizumi T., Miyagishi M., Taira K., Akira S., and Fujita T. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5 (2004) 730-737