-
1
-
-
0036318851
-
Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
-
Ahmad-Nejad, P., Hacker, H., Rutz, M., Bauer, S., Vabulas, R.M., and Wagner, H. (2002) Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 32: 1958-1968.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1958-1968
-
-
Ahmad-Nejad, P.1
Hacker, H.2
Rutz, M.3
Bauer, S.4
Vabulas, R.M.5
Wagner, H.6
-
2
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira, S., Uematsu, S., and Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124: 783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
3
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou, L., Holt, A.C., Medzhitov, R., and Flavell, R.A. (2001) Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413: 732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
4
-
-
65649083024
-
Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2
-
Bamming, D., and Horvath, C.M. (2009) Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2. J Biol Chem 284: 9700-9712.
-
(2009)
J Biol Chem
, vol.284
, pp. 9700-9712
-
-
Bamming, D.1
Horvath, C.M.2
-
5
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
Bauer, S., Kirschning, C.J., Hacker, H., Redecke, V., Hausmann, S., Akira, S., etal. (2001) Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Natl Acad Sci USA 98: 9237-9242.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9237-9242
-
-
Bauer, S.1
Kirschning, C.J.2
Hacker, H.3
Redecke, V.4
Hausmann, S.5
Akira, S.6
-
6
-
-
23344431978
-
The molecular structure of the Toll-like receptor 3 ligand-binding domain
-
Bell, J.K., Botos, I., Hall, P.R., Askins, J., Shiloach, J., Segal, D.M., etal. (2005) The molecular structure of the Toll-like receptor 3 ligand-binding domain. Proc Natl Acad Sci USA 102: 10976-10980.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10976-10980
-
-
Bell, J.K.1
Botos, I.2
Hall, P.R.3
Askins, J.4
Shiloach, J.5
Segal, D.M.6
-
7
-
-
84859427527
-
MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA
-
Berke, I.C., and Modis, Y. (2012) MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA. EMBO J 31: 1714-1726.
-
(2012)
EMBO J
, vol.31
, pp. 1714-1726
-
-
Berke, I.C.1
Modis, Y.2
-
8
-
-
84868538362
-
MDA5 assembles into a polar helical filament on double-stranded RNA
-
Berke, I.C., Yu, X., Modis, Y., and Egelman, E.H. (2012) MDA5 assembles into a polar helical filament on double-stranded RNA. Proc Natl Acad Sci USA 109: 18437-18441.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 18437-18441
-
-
Berke, I.C.1
Yu, X.2
Modis, Y.3
Egelman, E.H.4
-
9
-
-
31344476404
-
Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH
-
de Bouteiller, O., Merck, E., Hasan, U.A., Hubac, S., Benguigui, B., Trinchieri, G., etal. (2005) Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH. J Biol Chem 280: 38133-38145.
-
(2005)
J Biol Chem
, vol.280
, pp. 38133-38145
-
-
de Bouteiller, O.1
Merck, E.2
Hasan, U.A.3
Hubac, S.4
Benguigui, B.5
Trinchieri, G.6
-
10
-
-
23044445303
-
Crystal structure of human toll-like receptor 3 (TLR3) ectodomain
-
Choe, J., Kelker, M.S., and Wilson, I.A. (2005) Crystal structure of human toll-like receptor 3 (TLR3) ectodomain. Science 309: 581-585.
-
(2005)
Science
, vol.309
, pp. 581-585
-
-
Choe, J.1
Kelker, M.S.2
Wilson, I.A.3
-
11
-
-
80255141860
-
The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling
-
Civril, F., Bennett, M., Moldt, M., Deimling, T., Witte, G., Schiesser, S., etal. (2011) The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling. EMBO Rep 12: 1127-1134.
-
(2011)
EMBO Rep
, vol.12
, pp. 1127-1134
-
-
Civril, F.1
Bennett, M.2
Moldt, M.3
Deimling, T.4
Witte, G.5
Schiesser, S.6
-
12
-
-
38649089789
-
The C-terminal regulatory domain is the RNA 5′-triphosphate sensor of RIG-I
-
Cui, S., Eisenacher, K., Kirchhofer, A., Brzozka, K., Lammens, A., Lammens, K., etal. (2008) The C-terminal regulatory domain is the RNA 5′-triphosphate sensor of RIG-I. Mol Cell 29: 169-179.
-
(2008)
Mol Cell
, vol.29
, pp. 169-179
-
-
Cui, S.1
Eisenacher, K.2
Kirchhofer, A.3
Brzozka, K.4
Lammens, A.5
Lammens, K.6
-
13
-
-
84861653411
-
The 'complexities' of life and death: death receptor signalling platforms
-
Dickens, L.S., Powley, I.R., Hughes, M.A., and MacFarlane, M. (2012) The 'complexities' of life and death: death receptor signalling platforms. Exp Cell Res 318: 1269-1277.
-
(2012)
Exp Cell Res
, vol.318
, pp. 1269-1277
-
-
Dickens, L.S.1
Powley, I.R.2
Hughes, M.A.3
MacFarlane, M.4
-
14
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold, S.S., Kaisho, T., Hemmi, H., Akira, S., and Reis e Sousa, C. (2004) Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303: 1529-1531.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis e Sousa, C.5
-
15
-
-
57349191215
-
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
-
Ewald, S.E., Lee, B.L., Lau, L., Wickliffe, K.E., Shi, G.P., Chapman, H.A., etal. (2008) The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. Nature 456: 658-662.
-
(2008)
Nature
, vol.456
, pp. 658-662
-
-
Ewald, S.E.1
Lee, B.L.2
Lau, L.3
Wickliffe, K.E.4
Shi, G.P.5
Chapman, H.A.6
-
16
-
-
79955743119
-
Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase
-
Ewald, S.E., Engel, A., Lee, J., Wang, M., Bogyo, M., and Barton, G.M. (2011) Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase. J Exp Med 208: 643-651.
-
(2011)
J Exp Med
, vol.208
, pp. 643-651
-
-
Ewald, S.E.1
Engel, A.2
Lee, J.3
Wang, M.4
Bogyo, M.5
Barton, G.M.6
-
17
-
-
84861732291
-
Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily
-
Ferrao, R., Li, J., Bergamin, E., and Wu, H. (2012) Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily. Sci Signal 5: re3.
-
(2012)
Sci Signal
, vol.5
-
-
Ferrao, R.1
Li, J.2
Bergamin, E.3
Wu, H.4
-
18
-
-
84861861142
-
Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling
-
Garcia-Cattaneo, A., Gobert, F.X., Muller, M., Toscano, F., Flores, M., Lescure, A., etal. (2012) Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling. Proc Natl Acad Sci USA 109: 9053-9058.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 9053-9058
-
-
Garcia-Cattaneo, A.1
Gobert, F.X.2
Muller, M.3
Toscano, F.4
Flores, M.5
Lescure, A.6
-
19
-
-
79952100792
-
What the Myddosome structure tells us about the initiation of innate immunity
-
Gay, N.J., Gangloff, M., and O'Neill, L.A. (2011) What the Myddosome structure tells us about the initiation of innate immunity. Trends Immunol 32: 104-109.
-
(2011)
Trends Immunol
, vol.32
, pp. 104-109
-
-
Gay, N.J.1
Gangloff, M.2
O'Neill, L.A.3
-
20
-
-
44049095441
-
Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity
-
Gee, P., Chua, P.K., Gevorkyan, J., Klumpp, K., Najera, I., Swinney, D.C., etal. (2008) Essential role of the N-terminal domain in the regulation of RIG-I ATPase activity. J Biol Chem 283: 9488-9496.
-
(2008)
J Biol Chem
, vol.283
, pp. 9488-9496
-
-
Gee, P.1
Chua, P.K.2
Gevorkyan, J.3
Klumpp, K.4
Najera, I.5
Swinney, D.C.6
-
21
-
-
33748065439
-
Conserved features in the extracellular domain of human toll-like receptor 8 are essential for pH-dependent signaling
-
Gibbard, R.J., Morley, P.J., and Gay, N.J. (2006) Conserved features in the extracellular domain of human toll-like receptor 8 are essential for pH-dependent signaling. J Biol Chem 281: 27503-27511.
-
(2006)
J Biol Chem
, vol.281
, pp. 27503-27511
-
-
Gibbard, R.J.1
Morley, P.J.2
Gay, N.J.3
-
22
-
-
0242391997
-
The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
-
Heil, F., Ahmad-Nejad, P., Hemmi, H., Hochrein, H., Ampenberger, F., Gellert, T., etal. (2003) The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol 33: 2987-2997.
-
(2003)
Eur J Immunol
, vol.33
, pp. 2987-2997
-
-
Heil, F.1
Ahmad-Nejad, P.2
Hemmi, H.3
Hochrein, H.4
Ampenberger, F.5
Gellert, T.6
-
23
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., etal. (2004) Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303: 1526-1529.
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
-
24
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi, H., Kaisho, T., Takeuchi, O., Sato, S., Sanjo, H., Hoshino, K., etal. (2002) Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3: 196-200.
-
(2002)
Nat Immunol
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
-
25
-
-
33750976374
-
5′-Triphosphate RNA is the ligand for RIG-I
-
Hornung, V., Ellegast, J., Kim, S., Brzozka, K., Jung, A., Kato, H., etal. (2006) 5′-Triphosphate RNA is the ligand for RIG-I. Science 314: 994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
Kato, H.6
-
26
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
Hou, F., Sun, L., Zheng, H., Skaug, B., Jiang, Q.X., and Chen, Z.J. (2011) MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 146: 448-461.
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.1
Sun, L.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
Chen, Z.J.6
-
28
-
-
81555204380
-
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
-
Jiang, F., Ramanathan, A., Miller, M.T., Tang, G.Q., Gale, M., Patel, S.S., etal. (2011) Structural basis of RNA recognition and activation by innate immune receptor RIG-I. Nature 479: 423-427.
-
(2011)
Nature
, vol.479
, pp. 423-427
-
-
Jiang, F.1
Ramanathan, A.2
Miller, M.T.3
Tang, G.Q.4
Gale, M.5
Patel, S.S.6
-
29
-
-
84862994793
-
Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response
-
Jiang, X., Kinch, L.N., Brautigam, C.A., Chen, X., Du, F., Grishin, N.V., etal. (2012) Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response. Immunity 36: 959-973.
-
(2012)
Immunity
, vol.36
, pp. 959-973
-
-
Jiang, X.1
Kinch, L.N.2
Brautigam, C.A.3
Chen, X.4
Du, F.5
Grishin, N.V.6
-
30
-
-
80755140529
-
55 Amino acid linker between helicase and carboxyl terminal domains of RIG-I functions as a critical repression domain and determines inter-domain conformation
-
Kageyama, M., Takahasi, K., Narita, R., Hirai, R., Yoneyama, M., Kato, H., etal. (2011) 55 Amino acid linker between helicase and carboxyl terminal domains of RIG-I functions as a critical repression domain and determines inter-domain conformation. Biochem Biophys Res Commun 415: 75-81.
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 75-81
-
-
Kageyama, M.1
Takahasi, K.2
Narita, R.3
Hirai, R.4
Yoneyama, M.5
Kato, H.6
-
31
-
-
2442705429
-
Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3
-
Kariko, K., Bhuyan, P., Capodici, J., and Weissman, D. (2004) Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3. J Immunol 172: 6545-6549.
-
(2004)
J Immunol
, vol.172
, pp. 6545-6549
-
-
Kariko, K.1
Bhuyan, P.2
Capodici, J.3
Weissman, D.4
-
32
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., etal. (2006) Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441: 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
Matsui, K.6
-
33
-
-
46949097299
-
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5
-
Kato, H., Takeuchi, O., Mikamo-Satoh, E., Hirai, R., Kawai, T., Matsushita, K., etal. (2008) Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J Exp Med 205: 1601-1610.
-
(2008)
J Exp Med
, vol.205
, pp. 1601-1610
-
-
Kato, H.1
Takeuchi, O.2
Mikamo-Satoh, E.3
Hirai, R.4
Kawai, T.5
Matsushita, K.6
-
34
-
-
56549116047
-
Toll-like receptor and RIG-I-like receptor signaling
-
Kawai, T., and Akira, S. (2008) Toll-like receptor and RIG-I-like receptor signaling. Ann N Y Acad Sci 1143: 1-20.
-
(2008)
Ann N Y Acad Sci
, vol.1143
, pp. 1-20
-
-
Kawai, T.1
Akira, S.2
-
35
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
-
Kawai, T., and Akira, S. (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373-384.
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
36
-
-
80054703126
-
Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA
-
Kowalinski, E., Lunardi, T., McCarthy, A.A., Louber, J., Brunel, J., Grigorov, B., etal. (2011) Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA. Cell 147: 423-435.
-
(2011)
Cell
, vol.147
, pp. 423-435
-
-
Kowalinski, E.1
Lunardi, T.2
McCarthy, A.A.3
Louber, J.4
Brunel, J.5
Grigorov, B.6
-
37
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
Latz, E., Schoenemeyer, A., Visintin, A., Fitzgerald, K.A., Monks, B.G., Knetter, C.F., etal. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol 5: 190-198.
-
(2004)
Nat Immunol
, vol.5
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
Fitzgerald, K.A.4
Monks, B.G.5
Knetter, C.F.6
-
38
-
-
38349115933
-
The TLR3 signaling complex forms by cooperative receptor dimerization
-
Leonard, J.N., Ghirlando, R., Askins, J., Bell, J.K., Margulies, D.H., Davies, D.R., etal. (2008) The TLR3 signaling complex forms by cooperative receptor dimerization. Proc Natl Acad Sci USA 105: 258-263.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 258-263
-
-
Leonard, J.N.1
Ghirlando, R.2
Askins, J.3
Bell, J.K.4
Margulies, D.H.5
Davies, D.R.6
-
39
-
-
67651232539
-
Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5
-
Li, X., Lu, C., Stewart, M., Xu, H., Strong, R.K., Igumenova, T., etal. (2009) Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5. Arch Biochem Biophys 488: 23-33.
-
(2009)
Arch Biochem Biophys
, vol.488
, pp. 23-33
-
-
Li, X.1
Lu, C.2
Stewart, M.3
Xu, H.4
Strong, R.K.5
Igumenova, T.6
-
40
-
-
84863129261
-
DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature
-
Li, Y., Berke, I.C., and Modis, Y. (2012) DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature. EMBO J 31: 919-931.
-
(2012)
EMBO J
, vol.31
, pp. 919-931
-
-
Li, Y.1
Berke, I.C.2
Modis, Y.3
-
41
-
-
77953714711
-
Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
-
Lin, S.C., Lo, Y.C., and Wu, H. (2010) Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 465: 885-890.
-
(2010)
Nature
, vol.465
, pp. 885-890
-
-
Lin, S.C.1
Lo, Y.C.2
Wu, H.3
-
42
-
-
84861181618
-
The mitochondrial targeting chaperone 14-3-3epsilon regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity
-
Liu, H.M., Loo, Y.M., Horner, S.M., Zornetzer, G.A., Katze, M.G., and Gale, M., Jr (2012) The mitochondrial targeting chaperone 14-3-3epsilon regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity. Cell Host Microbe 11: 528-537.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 528-537
-
-
Liu, H.M.1
Loo, Y.M.2
Horner, S.M.3
Zornetzer, G.A.4
Katze, M.G.5
Gale Jr., M.6
-
43
-
-
42349090335
-
Structural basis of toll-like receptor 3 signaling with double-stranded RNA
-
Liu, L., Botos, I., Wang, Y., Leonard, J.N., Shiloach, J., Segal, D.M., etal. (2008) Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science 320: 379-381.
-
(2008)
Science
, vol.320
, pp. 379-381
-
-
Liu, L.1
Botos, I.2
Wang, Y.3
Leonard, J.N.4
Shiloach, J.5
Segal, D.M.6
-
44
-
-
37349052379
-
Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity
-
Loo, Y.M., Fornek, J., Crochet, N., Bajwa, G., Perwitasari, O., Martinez-Sobrido, L., etal. (2008) Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J Virol 82: 335-345.
-
(2008)
J Virol
, vol.82
, pp. 335-345
-
-
Loo, Y.M.1
Fornek, J.2
Crochet, N.3
Bajwa, G.4
Perwitasari, O.5
Martinez-Sobrido, L.6
-
45
-
-
80054685883
-
Structural insights into RNA recognition by RIG-I
-
Luo, D., Ding, S.C., Vela, A., Kohlway, A., Lindenbach, B.D., and Pyle, A.M. (2011) Structural insights into RNA recognition by RIG-I. Cell 147: 409-422.
-
(2011)
Cell
, vol.147
, pp. 409-422
-
-
Luo, D.1
Ding, S.C.2
Vela, A.3
Kohlway, A.4
Lindenbach, B.D.5
Pyle, A.M.6
-
46
-
-
84863523165
-
Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure
-
Luo, J., Obmolova, G., Malia, T.J., Wu, S.J., Duffy, K.E., Marion, J.D., etal. (2012) Lateral clustering of TLR3:dsRNA signaling units revealed by TLR3ecd:3Fabs quaternary structure. J Mol Biol 421: 112-124.
-
(2012)
J Mol Biol
, vol.421
, pp. 112-124
-
-
Luo, J.1
Obmolova, G.2
Malia, T.J.3
Wu, S.J.4
Duffy, K.E.5
Marion, J.D.6
-
47
-
-
78649635776
-
Molecular cell death platforms and assemblies
-
Mace, P.D., and Riedl, S.J. (2010) Molecular cell death platforms and assemblies. Curr Opin Cell Biol 22: 828-836.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 828-836
-
-
Mace, P.D.1
Riedl, S.J.2
-
48
-
-
0041331693
-
Subcellular localization of Toll-like receptor 3 in human dendritic cells
-
Matsumoto, M., Funami, K., Tanabe, M., Oshiumi, H., Shingai, M., Seto, Y., etal. (2003) Subcellular localization of Toll-like receptor 3 in human dendritic cells. J Immunol 171: 3154-3162.
-
(2003)
J Immunol
, vol.171
, pp. 3154-3162
-
-
Matsumoto, M.1
Funami, K.2
Tanabe, M.3
Oshiumi, H.4
Shingai, M.5
Seto, Y.6
-
49
-
-
27744526784
-
TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements
-
Nishiya, T., Kajita, E., Miwa, S., and Defranco, A.L. (2005) TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements. J Biol Chem 280: 37107-37117.
-
(2005)
J Biol Chem
, vol.280
, pp. 37107-37117
-
-
Nishiya, T.1
Kajita, E.2
Miwa, S.3
Defranco, A.L.4
-
50
-
-
84865060036
-
Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity
-
Onomoto, K., Jogi, M., Yoo, J.S., Narita, R., Morimoto, S., Takemura, A., etal. (2012) Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity. PLoS One 7: e43031.
-
(2012)
PLoS One
, vol.7
-
-
Onomoto, K.1
Jogi, M.2
Yoo, J.S.3
Narita, R.4
Morimoto, S.5
Takemura, A.6
-
51
-
-
56349114913
-
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9
-
Park, B., Brinkmann, M.M., Spooner, E., Lee, C.C., Kim, Y.M., and Ploegh, H.L. (2008) Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nat Immunol 9: 1407-1414.
-
(2008)
Nat Immunol
, vol.9
, pp. 1407-1414
-
-
Park, B.1
Brinkmann, M.M.2
Spooner, E.3
Lee, C.C.4
Kim, Y.M.5
Ploegh, H.L.6
-
52
-
-
33846702221
-
Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex
-
Park, H.H., Logette, E., Raunser, S., Cuenin, S., Walz, T., Tschopp, J., etal. (2007) Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex. Cell 128: 533-546.
-
(2007)
Cell
, vol.128
, pp. 533-546
-
-
Park, H.H.1
Logette, E.2
Raunser, S.3
Cuenin, S.4
Walz, T.5
Tschopp, J.6
-
53
-
-
84862909216
-
Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition
-
Peisley, A., Lin, C., Wu, B., Orme-Johnson, M., Liu, M., Walz, T., etal. (2011) Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition. Proc Natl Acad Sci USA 108: 21010-21015.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 21010-21015
-
-
Peisley, A.1
Lin, C.2
Wu, B.3
Orme-Johnson, M.4
Liu, M.5
Walz, T.6
-
54
-
-
67649232601
-
Identification of an N-terminal recognition site in TLR9 that contributes to CpG-DNA-mediated receptor activation
-
Peter, M.E., Kubarenko, A.V., Weber, A.N., and Dalpke, A.H. (2009) Identification of an N-terminal recognition site in TLR9 that contributes to CpG-DNA-mediated receptor activation. J Immunol 182: 7690-7697.
-
(2009)
J Immunol
, vol.182
, pp. 7690-7697
-
-
Peter, M.E.1
Kubarenko, A.V.2
Weber, A.N.3
Dalpke, A.H.4
-
55
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′ phosphates
-
Pichlmair, A., Schulz, O., Tan, C.P., Naslund, T.I., Liljestrom, P., Weber, F., etal. (2006) RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′ phosphates. Science 314: 997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Naslund, T.I.4
Liljestrom, P.5
Weber, F.6
-
56
-
-
84866558003
-
Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization
-
Qi, R., Singh, D., and Kao, C.C. (2012) Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization. J Biol Chem 287: 32617-32629.
-
(2012)
J Biol Chem
, vol.287
, pp. 32617-32629
-
-
Qi, R.1
Singh, D.2
Kao, C.C.3
-
57
-
-
84859959656
-
A molecular view on signal transduction by the apoptosome
-
Reubold, T.F., and Eschenburg, S. (2012) A molecular view on signal transduction by the apoptosome. Cell Signal 24: 1420-1425.
-
(2012)
Cell Signal
, vol.24
, pp. 1420-1425
-
-
Reubold, T.F.1
Eschenburg, S.2
-
58
-
-
33846307026
-
Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2
-
Saito, T., Hirai, R., Loo, Y.M., Owen, D., Johnson, C.L., Sinha, S.C., etal. (2007) Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci USA 104: 582-587.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 582-587
-
-
Saito, T.1
Hirai, R.2
Loo, Y.M.3
Owen, D.4
Johnson, C.L.5
Sinha, S.C.6
-
59
-
-
68049089651
-
Recognition of 5′ triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus
-
Schlee, M., Roth, A., Hornung, V., Hagmann, C.A., Wimmenauer, V., Barchet, W., etal. (2009) Recognition of 5′ triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. Immunity 31: 25-34.
-
(2009)
Immunity
, vol.31
, pp. 25-34
-
-
Schlee, M.1
Roth, A.2
Hornung, V.3
Hagmann, C.A.4
Wimmenauer, V.5
Barchet, W.6
-
60
-
-
39649092731
-
Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses
-
Takahasi, K., Yoneyama, M., Nishihori, T., Hirai, R., Kumeta, H., Narita, R., etal. (2008) Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses. Mol Cell 29: 428-440.
-
(2008)
Mol Cell
, vol.29
, pp. 428-440
-
-
Takahasi, K.1
Yoneyama, M.2
Nishihori, T.3
Hirai, R.4
Kumeta, H.5
Narita, R.6
-
61
-
-
67650510680
-
Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors
-
Takahasi, K., Kumeta, H., Tsuduki, N., Narita, R., Shigemoto, T., Hirai, R., etal. (2009) Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors. J Biol Chem 284: 17465-17474.
-
(2009)
J Biol Chem
, vol.284
, pp. 17465-17474
-
-
Takahasi, K.1
Kumeta, H.2
Tsuduki, N.3
Narita, R.4
Shigemoto, T.5
Hirai, R.6
-
62
-
-
64049090624
-
MAVS self-association mediates antiviral innate immune signaling
-
Tang, E.D., and Wang, C.Y. (2009) MAVS self-association mediates antiviral innate immune signaling. J Virol 83: 3420-3428.
-
(2009)
J Virol
, vol.83
, pp. 3420-3428
-
-
Tang, E.D.1
Wang, C.Y.2
-
63
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., Miyagishi, M., etal. (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5: 730-737.
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
-
64
-
-
23844438864
-
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity
-
Yoneyama, M., Kikuchi, M., Matsumoto, K., Imaizumi, T., Miyagishi, M., Taira, K., etal. (2005) Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 175: 2851-2858.
-
(2005)
J Immunol
, vol.175
, pp. 2851-2858
-
-
Yoneyama, M.1
Kikuchi, M.2
Matsumoto, K.3
Imaizumi, T.4
Miyagishi, M.5
Taira, K.6
-
65
-
-
77951708374
-
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
-
Zeng, W., Sun, L., Jiang, X., Chen, X., Hou, F., Adhikari, A., etal. (2010) Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell 141: 315-330.
-
(2010)
Cell
, vol.141
, pp. 315-330
-
-
Zeng, W.1
Sun, L.2
Jiang, X.3
Chen, X.4
Hou, F.5
Adhikari, A.6
|