Regulation of innate antiviral defenses through a shared repressor domain in RIG-1 and LGP2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 2, 2007, Pages 582-587

  Saito, Takeshi ^a   Hirai, Reiko ^b   Loo, Yueh Ming ^a   Owen, David ^a   Johnson, Cynthia L ^a   Sinha, Sangita C ^a   Akira, Shizuo ^c   Fujita, Takashi ^b   Gale Jr , Michael ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b KYOTO UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Cardif; Hepatitis C virus; IFN; IPS 1; MAVS

Indexed keywords

ADAPTOR PROTEIN; ALPHA INTERFERON; BETA INTERFERON; CASPASE RECRUITMENT DOMAIN PROTEIN; CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERFERON REGULATORY FACTOR 3; PROTEIN IPS 1; PROTEIN LGP2; PROTEIN MDA5; PROTEIN RIG I; REPRESSOR PROTEIN; RNA HELICASE; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIGEN RECOGNITION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; HEPATITIS C VIRUS; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNOREGULATION; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ANTIVIRAL AGENTS; CELL LINE; DEAD-BOX RNA HELICASES; HEPACIVIRUS; HUMANS; IMMUNITY, NATURAL; MODELS, IMMUNOLOGICAL; PROTEIN STRUCTURE, TERTIARY; RNA HELICASES; RNA, VIRAL; SIGNAL TRANSDUCTION;

HEPATITIS C VIRUS;

EID: 33846307026     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0606699104     Document Type: Article

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