Streptozotocin Intracerebroventricular-Induced Neurotoxicity and Brain Insulin Resistance: a Therapeutic Intervention for Treatment of Sporadic Alzheimer’s Disease (sAD)-Like Pathology

Molecular Neurobiology

Volumn 53, Issue 7, 2016, Pages 4548-4562

  Kamat, Pradip K ^a   Kalani, Anuradha ^b   Rai, Shivika ^c,d   Tota, Santosh Kumar ^c   Kumar, Ashok ^e   Ahmad, Abdullah S ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b University of Louisville School of Medicine   (United States)

^c CENTRAL DRUG RESEARCH INSTITUTE   (India)

^d ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

^e UNIVERSITY OF FLORIDA   (United States)

Author keywords

Alzheimer s disease; Insulin; Kinase; Neuroinflammation; Streptozotocin

Indexed keywords

ALZHEIMER DISEASE VACCINE; AMYLOID BETA PROTEIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIOXIDANT; CALCIUM CHANNEL BLOCKING AGENT; CHOLINESTERASE INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DONEPEZIL; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; IRON CHELATING AGENT; MELATONIN; MOOD STABILIZER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROTROPHIN DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PHENOL DERIVATIVE; PROTON PUMP INHIBITOR; QUERCETIN; RUTOSIDE; SILIBININ; STREPTOZOCIN; TACRINE; TAU PROTEIN; TESTOSTERONE; TRITERPENOID; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALZHEIMER DISEASE; CHEMICAL STRUCTURE; ENZYME ACTIVATION; HORMONE SUBSTITUTION; IMMUNOTHERAPY; INSULIN RESISTANCE; NERVOUS SYSTEM INFLAMMATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN PHOSPHORYLATION; REVIEW; SYNAPSE; ANIMAL; BRAIN; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; HUMAN; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; TREATMENT OUTCOME;

ALZHEIMER DISEASE; ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; INJECTIONS, INTRAVENTRICULAR; INSULIN RESISTANCE; OXIDATIVE STRESS; STREPTOZOCIN; TREATMENT OUTCOME;

EID: 84939864491     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9384-y     Document Type: Review

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