메뉴 건너뛰기




Volumn 61, Issue 7, 2012, Pages 1052-1064

Amelioration of intracerebroventricular streptozotocin induced cognitive impairment by Evolvulus alsinoides in rats: In vitro and in vivo evidence

Author keywords

Cholinesterase; Evolvulus alsinoides; In vitro; Oxidative stress; Rho kinase (ROCK II); Streptozotocin

Indexed keywords

ACETYLCHOLINESTERASE; BUTYRYLCHOLINESTRASE; CATECHOL METHYLTRANSFERASE; CHOLINESTERASE; EVOLVULUS ALSINOIDES EXTRACT; FLAVANOID; FREE RADICAL; GLUTATHIONE; GLYCOGEN SYNTHASE KINASE 3BETA; LIPOXYGENASE; MALONALDEHYDE; NITRIC OXIDE; PHENOL; PLANT EXTRACT; PROLYL ENDOPEPTIDASE; RHO KINASE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

EID: 84870058377     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2012.07.022     Document Type: Article
Times cited : (26)

References (69)
  • 1
    • 77649274672 scopus 로고    scopus 로고
    • Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat
    • R. Agrawal, B. Mishra, E. Tyagi, C. Nath, and R. Shukla Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat Pharmacol. Res. 61 2010 247 252
    • (2010) Pharmacol. Res. , vol.61 , pp. 247-252
    • Agrawal, R.1    Mishra, B.2    Tyagi, E.3    Nath, C.4    Shukla, R.5
  • 2
    • 60349128460 scopus 로고    scopus 로고
    • A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia
    • R. Agrawal, E. Tyagi, R. Shukla, and C. Nath A study of brain insulin receptors, AChE activity and oxidative stress in rat model of ICV STZ induced dementia Neuropharmacology 56 2009 779 787
    • (2009) Neuropharmacology , vol.56 , pp. 779-787
    • Agrawal, R.1    Tyagi, E.2    Shukla, R.3    Nath, C.4
  • 3
    • 11744367986 scopus 로고    scopus 로고
    • Antioxidative power of phytochemicals with special reference to cereals
    • W. Andlauer, and P. Fürst Antioxidative power of phytochemicals with special reference to cereals Cereal Foods World 43 1998 356 360
    • (1998) Cereal Foods World , vol.43 , pp. 356-360
    • Andlauer, W.1    Fürst, P.2
  • 4
    • 0025764520 scopus 로고
    • Longitudinal study on age-related changes of working and reference memory in the rat
    • S. Ando, and Y. Ohashi Longitudinal study on age-related changes of working and reference memory in the rat Neurosci. Lett. 128 1991 17 20
    • (1991) Neurosci. Lett. , vol.128 , pp. 17-20
    • Ando, S.1    Ohashi, Y.2
  • 5
    • 0037295775 scopus 로고    scopus 로고
    • Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases
    • B. Auddy, M. Ferreira, F. Blasina, L. Lafon, F. Arredondo, F. Dajas, P.C. Tripathi, T. Seal, and B. Mukherjee Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases J. Ethnopharmacol. 84 2003 131 138
    • (2003) J. Ethnopharmacol. , vol.84 , pp. 131-138
    • Auddy, B.1    Ferreira, M.2    Blasina, F.3    Lafon, L.4    Arredondo, F.5    Dajas, F.6    Tripathi, P.C.7    Seal, T.8    Mukherjee, B.9
  • 6
    • 73549106545 scopus 로고    scopus 로고
    • Protective effect of curcumin against intracerebral streptozotocin induced impairment in memory and cerebral blood flow
    • H. Awasthi, S. Tota, K. Hanif, C. Nath, and R. Shukla Protective effect of curcumin against intracerebral streptozotocin induced impairment in memory and cerebral blood flow Life Sci. 86 2010 87 94
    • (2010) Life Sci. , vol.86 , pp. 87-94
    • Awasthi, H.1    Tota, S.2    Hanif, K.3    Nath, C.4    Shukla, R.5
  • 7
    • 0028223375 scopus 로고
    • Behavioral and biochemical effects of an ICV injection of streptozotocin in old Lewis rats
    • A. Blokland, and J. Jolles Behavioral and biochemical effects of an ICV injection of streptozotocin in old Lewis rats Pharmacol. Biochem. Behav. 47 1994 833 837
    • (1994) Pharmacol. Biochem. Behav. , vol.47 , pp. 833-837
    • Blokland, A.1    Jolles, J.2
  • 8
    • 1842505677 scopus 로고    scopus 로고
    • Proteomics: A new approach to investigate oxidative stress in Alzheimer's disease brain
    • D.A. Butterfield Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain Brain Res. 1000 2004 1 7
    • (2004) Brain Res. , vol.1000 , pp. 1-7
    • Butterfield, D.A.1
  • 10
    • 17344380047 scopus 로고    scopus 로고
    • Extending applicability of the oxygen radical absorbance capacity (ORAC-fluorescein) assay
    • A. Davalos, C. Gomez-Cordoves, and B. Bartolome Extending applicability of the oxygen radical absorbance capacity (ORAC-fluorescein) assay J. Agric. Food Chem. 52 2004 48 54
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 48-54
    • Davalos, A.1    Gomez-Cordoves, C.2    Bartolome, B.3
  • 11
    • 18044383529 scopus 로고    scopus 로고
    • Cholinesterase inhibitors in the treatment of dementia
    • J.M. Ellis Cholinesterase inhibitors in the treatment of dementia J. Am. Osteopathol. Assoc. 105 2005 145 158
    • (2005) J. Am. Osteopathol. Assoc. , vol.105 , pp. 145-158
    • Ellis, J.M.1
  • 14
    • 42049114647 scopus 로고    scopus 로고
    • 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease
    • O. Firuzi, J. Zhuo, C.M. Chinnici, T. Wisniewski, and D. Praticò 5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease FASEB J. 22 2008 1169 1178
    • (2008) FASEB J. , vol.22 , pp. 1169-1178
    • Firuzi, O.1    Zhuo, J.2    Chinnici, C.M.3    Wisniewski, T.4    Praticò, D.5
  • 16
    • 13644268560 scopus 로고    scopus 로고
    • Oxidative stress in Alzheimer's disease
    • E.G. Gary, and H. Hsueh-Meei Oxidative stress in Alzheimer's disease Neurobiol. Aging 26 2005 575 578
    • (2005) Neurobiol. Aging , vol.26 , pp. 575-578
    • Gary, E.G.1    Hsueh-Meei, H.2
  • 17
    • 0013939811 scopus 로고
    • Regional studies of catecholamines in the rat brain - I. The disposition of [3H] norepinephrine, [3H] dopamine and [3H] dopa in various regions of the brain
    • J. Glowinski, and L.L. Iversen Regional studies of catecholamines in the rat brain - I. The disposition of [3H] norepinephrine, [3H] dopamine and [3H] dopa in various regions of the brain J. Neurochem. 13 1966 655 670
    • (1966) J. Neurochem. , vol.13 , pp. 655-670
    • Glowinski, J.1    Iversen, L.L.2
  • 18
    • 0027959041 scopus 로고
    • Nordihydroguaiaretic acid protects hippocampal neurons against amyloid beta-peptide toxicity, and attenuates free radical and calcium accumulation
    • Y. Goodman, M.R. Steiner, S.M. Steiner, and M.P. Mattson Nordihydroguaiaretic acid protects hippocampal neurons against amyloid beta-peptide toxicity, and attenuates free radical and calcium accumulation Brain Res. 654 1994 171 176
    • (1994) Brain Res. , vol.654 , pp. 171-176
    • Goodman, Y.1    Steiner, M.R.2    Steiner, S.M.3    Mattson, M.P.4
  • 20
    • 28844433048 scopus 로고    scopus 로고
    • Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid)
    • I. Gülçin Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid) Toxicology 217 2006 213 220
    • (2006) Toxicology , vol.217 , pp. 213-220
    • Gülçin, I.1
  • 21
    • 0028792111 scopus 로고
    • Lipid peroxidation and antioxidants as biomarkers of tissue damage
    • J.M. Gutteridge Lipid peroxidation and antioxidants as biomarkers of tissue damage Clin. Chem. 41 1995 1819 1828
    • (1995) Clin. Chem. , vol.41 , pp. 1819-1828
    • Gutteridge, J.M.1
  • 22
    • 70349125534 scopus 로고    scopus 로고
    • Molecular targets for the treatment of Alzheimer's disease
    • Seol-Heui Han Molecular targets for the treatment of Alzheimer's disease Dement. Neurol. Disord. 4 2005 53 58
    • (2005) Dement. Neurol. Disord. , vol.4 , pp. 53-58
    • Han, S.-H.1
  • 23
    • 41149114057 scopus 로고    scopus 로고
    • Acetylcholine esterase activity in mild cognitive impairment and Alzheimer's disease
    • K. Herholz Acetylcholine esterase activity in mild cognitive impairment and Alzheimer's disease Eur. J. Nucl. Med. Mol. Imaging 35 2008 S25 29
    • (2008) Eur. J. Nucl. Med. Mol. Imaging , vol.35 , pp. 25-29
    • Herholz, K.1
  • 24
    • 39849110726 scopus 로고    scopus 로고
    • The GSK3 hypothesis of Alzheimer's disease
    • C. Hooper, R. Killick, and S. Lovestone The GSK3 hypothesis of Alzheimer's disease J. Neurochem. 104 2008 1433 1439
    • (2008) J. Neurochem. , vol.104 , pp. 1433-1439
    • Hooper, C.1    Killick, R.2    Lovestone, S.3
  • 25
    • 84855189897 scopus 로고    scopus 로고
    • Changes in hippocampal synapses and learning-memory abilities in a streptozotocin-treated rat model and intervention by using fasudil hydrochloride
    • Y. Hou, L. Zhou, Q.D. Yang, X.P. Du, M. Li, M. Yuan, and Z.W. Zhou Changes in hippocampal synapses and learning-memory abilities in a streptozotocin-treated rat model and intervention by using fasudil hydrochloride Neuroscience 200 2012 120 129
    • (2012) Neuroscience , vol.200 , pp. 120-129
    • Hou, Y.1    Zhou, L.2    Yang, Q.D.3    Du, X.P.4    Li, M.5    Yuan, M.6    Zhou, Z.W.7
  • 26
    • 46149125926 scopus 로고    scopus 로고
    • Improvement of cognitive deficit and neuronal damage in rats with chronic cerebral ischemia via relative long-term inhibition of rho-kinase
    • L. Huang, Z. He, L. Guo, and H. Wang Improvement of cognitive deficit and neuronal damage in rats with chronic cerebral ischemia via relative long-term inhibition of rho-kinase Cell Mol. Neurobiol. 28 2008 757 768
    • (2008) Cell Mol. Neurobiol. , vol.28 , pp. 757-768
    • Huang, L.1    He, Z.2    Guo, L.3    Wang, H.4
  • 27
    • 33646596554 scopus 로고    scopus 로고
    • Coenzyme Q10 modulates cognitive impairment against intracerebro- ventricular infusion of streptozotocin in rats
    • T. Ishrat, M.B. Khan, M.N. Hoda, S. Yousuf, M. Ahmad, M.A. Ansari, A.S. Ahmad, and F. Islam Coenzyme Q10 modulates cognitive impairment against intracerebro-ventricular infusion of streptozotocin in rats Behav. Brain Res. 171 2006 9 16
    • (2006) Behav. Brain Res. , vol.171 , pp. 9-16
    • Ishrat, T.1    Khan, M.B.2    Hoda, M.N.3    Yousuf, S.4    Ahmad, M.5    Ansari, M.A.6    Ahmad, A.S.7    Islam, F.8
  • 28
    • 58149240957 scopus 로고    scopus 로고
    • Cognitive profiles in dementia: Alzheimer disease vs healthy brain aging
    • D.K. Johnson, M. Storandt, J.C. Morris, Z.D. Langford, and J.E. Galvin Cognitive profiles in dementia: Alzheimer disease vs healthy brain aging Neurology 71 2008 1783 1789
    • (2008) Neurology , vol.71 , pp. 1783-1789
    • Johnson, D.K.1    Storandt, M.2    Morris, J.C.3    Langford, Z.D.4    Galvin, J.E.5
  • 29
    • 0030822531 scopus 로고    scopus 로고
    • Prevention of Amyloid-like deposition by a selective prolyl endopeptidase inhibitor, Y-29794, in senescence-accelerated mouse
    • A. Kato, A. Fukunari, S. Yoko, and N. Tohru Prevention of Amyloid-like deposition by a selective prolyl endopeptidase inhibitor, Y-29794, in senescence-accelerated mouse J. Pharmacol. Exp. Ther. 283 1997 328 335
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 328-335
    • Kato, A.1    Fukunari, A.2    Yoko, S.3    Tohru, N.4
  • 33
    • 3042753797 scopus 로고    scopus 로고
    • Microplate screening assay to identify inhibitors of human catechol-O-methyltransferase
    • M. Kurkela, A. Siiskonen, M. Finel, P. Tammela, J. Taskinen, and P. Vuorela Microplate screening assay to identify inhibitors of human catechol-O-methyltransferase Anal. Biochem. 331 2004 198 200
    • (2004) Anal. Biochem. , vol.331 , pp. 198-200
    • Kurkela, M.1    Siiskonen, A.2    Finel, M.3    Tammela, P.4    Taskinen, J.5    Vuorela, P.6
  • 34
    • 0031797937 scopus 로고    scopus 로고
    • Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats
    • H. Lannert, and S. Hoyer Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats Behav. Neurosci. 112 1998 1199 1208
    • (1998) Behav. Neurosci. , vol.112 , pp. 1199-1208
    • Lannert, H.1    Hoyer, S.2
  • 36
    • 0038491473 scopus 로고    scopus 로고
    • Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics
    • R. Liu, I.Y. Liu, X. Bi, R.F. Thompson, S.R. Doctrow, B. Malfroy, and M. Baudry Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics Proc. Natl. Acad. Sci. USA 100 2001 8526 8531
    • (2001) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8526-8531
    • Liu, R.1    Liu, I.Y.2    Bi, X.3    Thompson, R.F.4    Doctrow, S.R.5    Malfroy, B.6    Baudry, M.7
  • 37
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • J.J. Lucas, F. Hernández, P. Gómez-Ramos, M.A. Morán, R. Hen, and J. Avila Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice EMBO J. 20 2001 27 39
    • (2001) EMBO J. , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernández, F.2    Gómez-Ramos, P.3    Morán, M.A.4    Hen, R.5    Avila, J.6
  • 38
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • S. Marklund, and G. Marklund Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase Eur. J. Biochem. 47 1974 469 474
    • (1974) Eur. J. Biochem. , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 39
    • 15344344684 scopus 로고    scopus 로고
    • Diagnosis and treatment of Alzheimer's disease
    • M. Monczor Diagnosis and treatment of Alzheimer's disease Curr. Med. Chem - CNS Agents 5 2005 5 13
    • (2005) Curr. Med. Chem - CNS Agents , vol.5 , pp. 5-13
    • Monczor, M.1
  • 40
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • R. Morris Developments of a water-maze procedure for studying spatial learning in the rat J. Neurosci. Methods 11 1984 47 60
    • (1984) J. Neurosci. Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 41
    • 37849032383 scopus 로고    scopus 로고
    • Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity
    • P.K. Mukherjee, V. Kumar, and P.J. Houghton Screening of Indian medicinal plants for acetylcholinesterase inhibitory activity Phytother. Res. 21 2007 1142 1145
    • (2007) Phytother. Res. , vol.21 , pp. 1142-1145
    • Mukherjee, P.K.1    Kumar, V.2    Houghton, P.J.3
  • 42
    • 77951534184 scopus 로고    scopus 로고
    • Effect of E. alsinoides Linn. on learning behavior and memory enhancement activity in rodents
    • A. Nahata, U.K. Patil, and V.K. Dixit Effect of E. alsinoides Linn. on learning behavior and memory enhancement activity in rodents Phytother. Res. 24 2010 486 493
    • (2010) Phytother. Res. , vol.24 , pp. 486-493
    • Nahata, A.1    Patil, U.K.2    Dixit, V.K.3
  • 44
    • 0025737376 scopus 로고
    • Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex
    • R. Nitsch, and S. Hoyer Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex Neurosci. Lett. 128 1991 199 202
    • (1991) Neurosci. Lett. , vol.128 , pp. 199-202
    • Nitsch, R.1    Hoyer, S.2
  • 45
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animals tissues by thiobarbituric acid reaction
    • H. Ohkawa, N. Ohishi, and K. Yagi Assay for lipid peroxides in animals tissues by thiobarbituric acid reaction Anal. Biochem. 95 1979 351 358
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 46
    • 48249087702 scopus 로고    scopus 로고
    • Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity
    • I. Orhan, F. Tosun, and B. Sener Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity Z. Naturforsch, C. 63 2008 366 370
    • (2008) Z. Naturforsch, C. , vol.63 , pp. 366-370
    • Orhan, I.1    Tosun, F.2    Sener, B.3
  • 47
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • P.G. Pietta Flavonoids as antioxidants J. Nat. Prod. 63 2000 1035 1042
    • (2000) J. Nat. Prod. , vol.63 , pp. 1035-1042
    • Pietta, P.G.1
  • 48
    • 0029977323 scopus 로고    scopus 로고
    • New prolyl endopeptidase inhibitors: In vitro and in vivo activities of azabicyclo[2.2.2] octane, azabicyclo[2.2.1]heptane, and perhydroindole derivatives
    • B. Portevin, A. Benoist, G. Remond, Y. Herve, M. Vincent, J. Lepagnol, and G. De Nanteuil New prolyl endopeptidase inhibitors: in vitro and in vivo activities of azabicyclo[2.2.2] octane, azabicyclo[2.2.1]heptane, and perhydroindole derivatives J. Med. Chem. 39 1996 2379 2391
    • (1996) J. Med. Chem. , vol.39 , pp. 2379-2391
    • Portevin, B.1    Benoist, A.2    Remond, G.3    Herve, Y.4    Vincent, M.5    Lepagnol, J.6    De Nanteuil, G.7
  • 50
    • 71849093750 scopus 로고    scopus 로고
    • Curcumin is protective against phenytoin-induced cognitive impairment and oxidative stress in rats
    • K.H. Reeta, J. Mehla, and Y.K. Gupta Curcumin is protective against phenytoin-induced cognitive impairment and oxidative stress in rats Brain Res. 1301 2009 52 60
    • (2009) Brain Res. , vol.1301 , pp. 52-60
    • Reeta, K.H.1    Mehla, J.2    Gupta, Y.K.3
  • 51
    • 34249661686 scopus 로고    scopus 로고
    • Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice
    • G. Saxena, S.P. Singh, R. Pal, S. Singh, R. Pratap, and C. Nath Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice Pharmacol. Biochem. Behav. 86 2007 797 805
    • (2007) Pharmacol. Biochem. Behav. , vol.86 , pp. 797-805
    • Saxena, G.1    Singh, S.P.2    Pal, R.3    Singh, S.4    Pratap, R.5    Nath, C.6
  • 52
    • 79952017778 scopus 로고    scopus 로고
    • Free radicals, antioxidant, disease and phytomedicines: Current status and future prospect
    • S. Sen, R. Chakraborty, C. Sridhar, Y.S.R. Reddy, and B. De Free radicals, antioxidant, disease and phytomedicines: current status and future prospect Int. J. Pharm. Sci. Rev. Res. 3 2010 91 100
    • (2010) Int. J. Pharm. Sci. Rev. Res. , vol.3 , pp. 91-100
    • Sen, S.1    Chakraborty, R.2    Sridhar, C.3    Reddy, Y.S.R.4    De, B.5
  • 53
    • 0041347741 scopus 로고    scopus 로고
    • Effect of alpha lipoic acid on intracerebroventricular streptozotocin model of cognitive impairment in rats
    • M. Sharma, and Y.K. Gupta Effect of alpha lipoic acid on intracerebroventricular streptozotocin model of cognitive impairment in rats Eur. Neuropsychopharmacol. 13 2003 241 247
    • (2003) Eur. Neuropsychopharmacol. , vol.13 , pp. 241-247
    • Sharma, M.1    Gupta, Y.K.2
  • 55
    • 74149094268 scopus 로고    scopus 로고
    • Umbelliferone - An antioxidant isolated from Acacia nilotica (L.) Willd. Ex. Del
    • R. Singh, B. Singh, S. Singh, N. Kumar, S. Kumar, and S. Arora Umbelliferone - an antioxidant isolated from Acacia nilotica (L.) Willd. Ex. Del. Food Chem. 120 2010 825 830
    • (2010) Food Chem. , vol.120 , pp. 825-830
    • Singh, R.1    Singh, B.2    Singh, S.3    Kumar, N.4    Kumar, S.5    Arora, S.6
  • 56
    • 0000359845 scopus 로고
    • Colorimetry of total phenolics with phosphomolybdic phosphotungstic acid reagents
    • V.L. Singleton, and Jr. Rossi Colorimetry of total phenolics with phosphomolybdic phosphotungstic acid reagents Am. J. Enol. Viticult. 16 1965 144 158
    • (1965) Am. J. Enol. Viticult. , vol.16 , pp. 144-158
    • Singleton, V.L.1    Rossi, J.R.2
  • 58
    • 20944442186 scopus 로고    scopus 로고
    • Alzheimer's associated inflammation, potential drug targets and future therapies
    • G. Stuchbury, and G. Munch Alzheimer's associated inflammation, potential drug targets and future therapies J. Neural Transm. 112 2005 429 453
    • (2005) J. Neural Transm. , vol.112 , pp. 429-453
    • Stuchbury, G.1    Munch, G.2
  • 60
    • 0031695652 scopus 로고    scopus 로고
    • Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons
    • A. Takashima, T. Honda, K. Yasutake, G. Michel, O. Murayama, M. Murayama, K. Ishiguro, and H. Yamaguchi Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons Neurosci. Res. 31 1998 317 323
    • (1998) Neurosci. Res. , vol.31 , pp. 317-323
    • Takashima, A.1    Honda, T.2    Yasutake, K.3    Michel, G.4    Murayama, O.5    Murayama, M.6    Ishiguro, K.7    Yamaguchi, H.8
  • 61
    • 0029027926 scopus 로고
    • JTP-4819, a novel PEP inhibitor with potential as cognitive enhancer
    • K. Toide, Y. Iwamoto, T. Fujiwara, and H. Abe JTP-4819, a novel PEP inhibitor with potential as cognitive enhancer J. Pharmacol. Exp. Ther. 274 1995 1370 1378
    • (1995) J. Pharmacol. Exp. Ther. , vol.274 , pp. 1370-1378
    • Toide, K.1    Iwamoto, Y.2    Fujiwara, T.3    Abe, H.4
  • 62
    • 77249130189 scopus 로고    scopus 로고
    • Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice
    • S. Tota, H. Awasthi, P.K. Kamat, C. Nath, and K. Hanif Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice Behav. Brain Res. 209 2010 73 79
    • (2010) Behav. Brain Res. , vol.209 , pp. 73-79
    • Tota, S.1    Awasthi, H.2    Kamat, P.K.3    Nath, C.4    Hanif, K.5
  • 63
    • 61349185049 scopus 로고    scopus 로고
    • Candesartan improves memory decline in mice: Involvement of AT1 receptors in memory deficit induced by intracerebral streptozotocin
    • S. Tota, P.K. Kamat, H. Awasthi, N. Singh, R. Raghubir, C. Nath, and K. Hanif Candesartan improves memory decline in mice: involvement of AT1 receptors in memory deficit induced by intracerebral streptozotocin Behav. Brain Res. 199 2009 235 240
    • (2009) Behav. Brain Res. , vol.199 , pp. 235-240
    • Tota, S.1    Kamat, P.K.2    Awasthi, H.3    Singh, N.4    Raghubir, R.5    Nath, C.6    Hanif, K.7
  • 64
    • 0038809806 scopus 로고    scopus 로고
    • Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats
    • M.H. Veerendra Kumar, and Y.K. Gupta Effect of Centella asiatica on cognition and oxidative stress in an intracerebroventricular streptozotocin model of Alzheimer's disease in rats Clin. Exp. Pharmacol. Physiol. 30 2003 336 342
    • (2003) Clin. Exp. Pharmacol. Physiol. , vol.30 , pp. 336-342
    • Veerendra Kumar, M.H.1    Gupta, Y.K.2
  • 65
    • 58149392154 scopus 로고    scopus 로고
    • Impairment in emotion recognition abilities in patients with mild cognitive impairment, early and moderate Alzheimer disease compared with healthy comparison subjects
    • E.M. Weiss, C.G. Kohler, J. Vonbank, E. Stadelmann, G. Kemmler, H. Hinterhuber, and J. Marksteiner Impairment in emotion recognition abilities in patients with mild cognitive impairment, early and moderate Alzheimer disease compared with healthy comparison subjects Am. J. Geriatr. Psychiatry 16 2008 974 980
    • (2008) Am. J. Geriatr. Psychiatry , vol.16 , pp. 974-980
    • Weiss, E.M.1    Kohler, C.G.2    Vonbank, J.3    Stadelmann, E.4    Kemmler, G.5    Hinterhuber, H.6    Marksteiner, J.7
  • 67
    • 33746508651 scopus 로고    scopus 로고
    • Peroxynitrite induces Alzheimer-like tau modifications and accumulation in rat brain and its underlying mechanisms
    • Y.J. Zhang, Y.F. Xu, Y.H. Liu, J. Yin, H.L. Li, Q. Wang, and J.Z. Wang Peroxynitrite induces Alzheimer-like tau modifications and accumulation in rat brain and its underlying mechanisms FASEB J. 20 2006 1431 1442
    • (2006) FASEB J. , vol.20 , pp. 1431-1442
    • Zhang, Y.J.1    Xu, Y.F.2    Liu, Y.H.3    Yin, J.4    Li, H.L.5    Wang, Q.6    Wang, J.Z.7
  • 68
    • 0033004729 scopus 로고    scopus 로고
    • The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals
    • J. Zhishen, T. Mengcheng, and W. Jianming The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals Food Chem. 64 1999 555 559
    • (1999) Food Chem. , vol.64 , pp. 555-559
    • Zhishen, J.1    Mengcheng, T.2    Jianming, W.3
  • 69
    • 59849118023 scopus 로고    scopus 로고
    • Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee
    • B.T. Zhu, P. Wang, M. Nagai, Y. Wen, and H.W. Bai Inhibition of human catechol-O-methyltransferase (COMT)-mediated O-methylation of catechol estrogens by major polyphenolic components present in coffee J. Steroid Biochem. Mol. Biol. 113 2009 65 74
    • (2009) J. Steroid Biochem. Mol. Biol. , vol.113 , pp. 65-74
    • Zhu, B.T.1    Wang, P.2    Nagai, M.3    Wen, Y.4    Bai, H.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.