Protection of streptozotocin induced insulin receptor dysfunction, neuroinflammation and amyloidogenesis in astrocytes by insulin

Neuropharmacology

Volumn 86, Issue , 2014, Pages 337-352

  Rajasekar, N ^a,b   Dwivedi, Subhash ^a   Nath, Chandishwar ^a,b   Hanif, Kashif ^a,b   Shukla, Rakesh ^a,b  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

Amyloidogenic protein expression; Astrocytes; Glial insulin signaling; Neuroinflammation; Streptozotocin

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; CASPASE; CYCLOOXYGENASE 2; GLIAL FIBRILLARY ACIDIC PROTEIN; INSULIN; INSULIN RECEPTOR; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; STREPTOZOCIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; AMYLOID; NEUROPROTECTIVE AGENT;

AMYLOIDOGENESIS; ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL PROTECTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; GENE EXPRESSION; INSULIN RECEPTOR GENE; MOLECULAR PATHOLOGY; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NEUROTOXICITY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL SURVIVAL; DRUG EFFECTS; IMMUNOMODULATION; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

AMYLOID; ANIMALS; APOPTOSIS; ASTROCYTES; CELL LINE, TUMOR; CELL SURVIVAL; INSULIN; NEUROIMMUNOMODULATION; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RECEPTOR, INSULIN; STREPTOZOCIN;

EID: 84907729319     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.08.013     Document Type: Article

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